ライフサイエンスコーパス: tectorial membrane

1 s similar in dead mice and in mice lacking a tectorial membrane.

2 chanical coupling of outer hair cells to the tectorial membrane.

3 hearing between the reticular lamina and the tectorial membrane.

4 ir cell stereocilia by mirroring them on the tectorial membrane.

5 als for precise collagen organisation in the tectorial membrane.

6 to produce fast lateral displacements of the tectorial membrane.

7 id-filled space between reticular lamina and tectorial membrane.

8 nd influences the physical properties of the tectorial membrane.

9 d graded mechanical properties of guinea pig tectorial membrane.

10 affects interactions of stereocilia with the tectorial membrane.

11 and sensory epithelium, and deformity of the tectorial membrane.

12 mechanical link of outer hair cells with the tectorial membrane.

13 lia to maintain stable interactions with the tectorial membrane.

14 ilar membrane, the reticular lamina, and the tectorial membrane.

15 of the outer hair cells are imbedded in the tectorial membrane, a sheet of extracellular matrix that

16 non-syndromic hearing loss, and suggest that tectorial membrane abnormalities may be one aetiology of

17 These mutants have tectorial membrane abnormalities, including a prominent

18 rin (encoded by Tecta) is a component of the tectorial membrane, an extracellular matrix of the cochl

19 beta-tectorin reveal multiple roles for the tectorial membrane, an extracellular matrix unique to th

20 silar membrane, the radial vibrations of the tectorial membrane and reticular lamina were tuned.

21 structures that deflect the OHC bundle, the tectorial membrane and reticular lamina, to the transver

22 imulate the outer hair cell stereocilia, the tectorial membrane and reticular lamina, were sharply tu

23 ations, except in the narrow gap between the tectorial membrane and reticular lamina, where lubricati

24 ted to a reduction in the acting mass of the tectorial membrane and reveal a new function for this st

25 interactions between the organ of Corti, the tectorial membrane and the subtectorial fluid, and/or el

26 th (especially of the inner hair cells), the tectorial membrane appeared to be more resistant to post

27 stic trachea as well as the extension of the tectorial membrane are not correlated to the tonotopy.

28 real cochlea, the motions of the basilar and tectorial membranes are fundamentally different during i

29 ir bundles are not attached to the overlying tectorial membrane, are a notable exception.

30 , tip links are only sensitive to BAPTA, and tectorial membrane attachment crowns are removed by subt

31 nks appear around the base of the bundle and tectorial membrane attachment crowns are seen at the ste

32 s: tip links, horizontal top connectors, and tectorial membrane attachment crowns.

33 The radial stiffness of the tectorial membrane attachment was found to be a crucial

34 The tectorial membrane contains radially organized collagen

35 of Corti sandwiched between the basilar and tectorial membranes, contains the outer hair cells that

36 gap size between the IHC stereocilia and the tectorial membrane determine the characteristic frequenc

37 Combined with the changes in tectorial membrane dimensions from base to apex, the rad

38 Because the tectorial membrane directly overlies the inner hair cell

39 ticular lamina greatly surpasses that of the tectorial membrane, giving rise to shear that deflects t

40 al workings of the organ of Corti and of the tectorial membrane have resisted exploration.

41 tically isolated a second major role for the tectorial membrane in hearing: it enables the motion of

42 s with electron-lucent cytoplasm; and 4) the tectorial membrane in the BWC papilla was narrow, coveri

43 r noncollagenous components of the mammalian tectorial membrane in the inner ear.

44 in a cross section of the organ of Corti and tectorial membrane in the mammalian cochlea, and quantif

45 ctorin (Tecta) is a major constituent of the tectorial membrane in the mammalian cochlea.

46 r matrices, including otoconial, cupular and tectorial membranes, in Oc90 null mice, likely due to an

47 The tectorial membrane is an extracellular structure of the

48 ated in Tecta(C1509G/C1509G) mice, where the tectorial membrane is detached from OHC stereocilia, arg

49 micromechanics of the organ of Corti and the tectorial membrane is then analyzed by our new method.

50 band, when the hair bundle was loaded with a tectorial membrane mass.

51 a imprint pattern at the undersurface of the tectorial membrane may provide a way to detect possible

52 ngs are as follows: The reticular lamina and tectorial membrane move in unison with essentially no sq

53 chlear resonance, presumably the basilar and tectorial membranes, move together in phase during the o

54 l and Deiters cells and was deposited in the tectorial membrane of the cochlea between postnatal days

55 Electron microscopy of the tectorial membrane of these mice revealed loss of organi

56 ably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and b

57 Inertial loading of a hair bundle by the tectorial membrane reduces the bundle's reactive load, a

58 lear partition upon tip-link destruction and tectorial-membrane removal, suggesting that these struct

59 otion were hundreds of times larger than the tectorial membrane, reticular lamina (RL), and pillar ce

60 ene mutation for alpha-tectorin indicate the tectorial membrane's key role in the mechanoelectrical t

61 abnormalities do not seriously influence the tectorial membrane's known role in ensuring that cochlea

62 mice with the Y1870C mutation in Tecta, the tectorial membrane's matrix structure is disrupted, and

63 e inner ear, direct experimental data on the tectorial membrane's physical properties are limited, an

64 the hemicochlea, we are able to show that a tectorial membrane stiffness gradient exists along the c

65 Unlike the natural situation where the tectorial membrane stimulates hair-cell stereocilia even

66 also exhibited obvious abnormalities in the tectorial membrane, supporting cells, and Reissner's mem

67 We found that the tectorial membrane sustains traveling wave propagation.

68 ar motion and endolymphatic flow between the tectorial membrane (TM) and reticular lamina (RL), is co

69 The tectorial membrane (TM) clearly plays a mechanical role

70 The tectorial membrane (TM) has a significantly larger stiff

71 However, genetic studies targeting the tectorial membrane (TM) have demonstrated both sharper a

72 were used to measure shear impedance of the tectorial membrane (TM) in two dimensions.

73 The solid component of the tectorial membrane (TM) is a porous matrix made up of th

74 The tectorial membrane (TM) is widely believed to play an im

75 The tectorial membrane (TM) of the mammalian cochlea is a co

76 relation and the pore radius of the isolated tectorial membrane (TM) of the mouse were determined.

77 altering the mechanical load applied by the tectorial membrane (TM) on the outer hair cell HB.

78 ent studies suggest that wave motions of the tectorial membrane (TM) play a critical role in determin

79 The tectorial membrane (TM) plays a key role in this process

80 e spatial extent and propagation velocity of tectorial membrane (TM) travelling waves and that these

81 The motion of the tectorial membrane (TM) with respect to the reticular la

82 In the Otoa(EGFP/EGFP) mouse, the tectorial membrane (TM), a ribbon-like strip of ECM that

83 is a modular, non-collagenous protein of the tectorial membrane (TM), an extracellular matrix of the

84 creted glycoproteins that are present in the tectorial membrane (TM), an extracellular structure over

85 , and DC shift on the basilar membrane (BM), tectorial membrane (TM), and OHC potentials are predicte

86 uency selectivity and wave properties of the tectorial membrane (TM).

87 the BM and another extracellular matrix, the tectorial membrane (TM).

88 the tips of the tallest stereocilia and the tectorial membrane (TM).

89 pared with basilar membrane traveling waves, tectorial membrane traveling waves have larger dynamic r

90 uted to decreases in spread of excitation of tectorial membrane traveling waves.

91 in the hair cell epithelium is distinct from tectorial membrane tuning.

92 ort, to our knowledge, the first measures of tectorial membrane vibration within the unopened cochlea

93 ere we show that the spread of excitation of tectorial membrane waves is similar in humans and mice,

94 In cochlear sections of Ceacam16(-/-) mice tectorial membranes were significantly more often stretc