ライフサイエンスコーパス: telomerase reverse transcriptase

1 humans, rather than endogenous mTERT (mouse telomerase reverse transcriptase).

2 erase RNA; hTER) and the core protein (human telomerase reverse transcriptase).

3 NA) and a protein subunit named hTERT (human telomerase reverse transcriptase).

4 ) decreases the mRNA expression of the human telomerase reverse transcriptase.

5 the MRP ribonucleoprotein ribozyme and human telomerase reverse transcriptase.

6 form stable complexes with the TEN domain of telomerase reverse transcriptase.

7 nds to a peptide sequence derived from human telomerase reverse transcriptase.

8 tative polymerase chain reaction using human telomerase reverse transcriptase.

9 higher-order multimers of telomerase RNA and telomerase reverse transcriptase.

10 -circle formation in normal cells expressing telomerase reverse transcriptase.

11 he synthesis of the telomeric repeats by the telomerase reverse transcriptase.

12 f two genes, asparagine synthetase and human telomerase reverse transcriptase.

13 otide that targets the RNA template of human telomerase reverse transcriptase.

14 and P6.1 to correctly fold and interact with telomerase reverse transcriptase.

15 nts with heterozygous mutations in TERT, the telomerase reverse transcriptase, a 50% reduction in tel

16 ligo also inhibited mRNA expression of human telomerase reverse transcriptase, a catalytic subunit of

17 The telomerase reverse transcriptase adds de novo DNA repeat

18 n Atm(-/-) mice engineered with an inducible telomerase reverse transcriptase allele.

19 Telomerases from all organisms contain a telomerase reverse transcriptase and a telomerase RNA (T

20 rmore, we showed that reducing expression of telomerase reverse transcriptase and telomerase activity

21 tations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, res

22 ikely to change conformation in complex with telomerase reverse transcriptase and that it provides a

23 tumor antigen vaccine derived from the human telomerase reverse transcriptase and the antiapoptotic p

24 the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play

25 Thus, p43 joins the telomerase reverse transcriptase and the yeast proteins

26 riction decreased expression of hTERT (human telomerase reverse transcriptase) and increased expressi

27 expressed higher levels of K5, CD133, Oct4, telomerase reverse transcriptase, and C-X-C chemokine li

28 iched for expression of Ki-67, ZAP-70, human telomerase reverse transcriptase, and telomerase activit

29 ry, these data suggest that cells expressing telomerase reverse transcriptase are not a progenitor-ce

30 tension (CTE) domain of Arabidopsis thaliana telomerase reverse transcriptase as baits to screen an A

31 d beta1 integrins, DeltaNp63alpha, CD44, and telomerase reverse transcriptase, as well as decreased N

32 ted from chimera mice expressed collagen and telomerase reverse transcriptase but not alpha-smooth mu

33 n) were identified in TERT, the gene for the telomerase reverse transcriptase catalytic enzyme, among

34 ertion in fingers domain" (IFD) in the human telomerase reverse transcriptase catalytic subunit (hTER

35 ll-known "telomere disorder." RMRP binds the telomerase reverse transcriptase (catalytic subunit) in

36 ular and cytogenetic features of the chicken telomerase reverse transcriptase (chTERT) gene and prote

37 use myocardium, and transgenic expression of telomerase reverse transcriptase conferred protection fr

38 were consistently more effective than PSA or telomerase reverse transcriptase CTL to lyse tumor targe

39 lmonary fibrosis by activation of fibroblast telomerase reverse transcriptase-dependent proliferation

40 for malignant behavior, expression of human telomerase reverse transcriptase enabled cells from seri

41 lls, whereas interleukin-31 strongly induced telomerase reverse transcriptase expression in fibroblas

42 report that BRCA1 knockdown causes increased telomerase reverse transcriptase expression, telomerase

43 The organization of the t/PK on telomerase reverse transcriptase for medaka and human is

44 ss various N-terminal fusion proteins of the telomerase reverse transcriptase from its endogenous loc

45 f renal tumor-associated antigens, including telomerase reverse transcriptase, G250, and oncofetal an

46 -Myc can activate transcription of the human telomerase reverse transcriptase gene (hTERT), we addres

47 oted c-Myc-dependent expression of the human telomerase reverse transcriptase gene (hTERT).

48 ty, which is accompanied by induction of the telomerase reverse transcriptase gene (TERT).

49 hromosomal region at 5p15.33 proximal of the telomerase reverse transcriptase gene (TERT).

50 ecruited by Myc to the promoter of the human telomerase reverse transcriptase gene, and p300/CBP stim

51 mice was not affected by inactivation of the telomerase reverse transcriptase gene, indicating that e

52 ome clone containing the entire hTERT (human telomerase reverse transcriptase) gene was introduced in

53 in TERC (telomerase RNA component) and TERT (telomerase reverse transcriptase) have been found in aut

54 When Fancc(-/-) mice were crossed into a telomerase reverse transcriptase heterozygous or null ba

55 The human telomerase reverse transcriptase hTERT is highly express

56 therapy, the immunological properties of the telomerase reverse transcriptase hTERT suggest that the

57 Here, we demonstrate that human telomerase reverse transcriptase (hTERT) activates vascu

58 the core components of telomerase, the human telomerase reverse transcriptase (hTERT) and associated

59 dopts a new conformation on binding to human telomerase reverse transcriptase (hTERT) and reconstitut

60 LA-DR-restricted peptides derived from human telomerase reverse transcriptase (hTERT) and referred as

61 Higher expression of human telomerase reverse transcriptase (hTERT) and subsequent

62 In humans, this enzyme is composed of the telomerase reverse transcriptase (hTERT) and telomerase

63 , the cells were exposed to retroviral human telomerase reverse transcriptase (hTERT) and/or SV40 lar

64 Mutations in the gene for telomerase reverse transcriptase (hTERT) are associated

65 S signaling pathways and activation of human telomerase reverse transcriptase (hTERT) are common in h

66 expression and telomerase activity of human telomerase reverse transcriptase (hTERT) are hallmarks o

67 The mRNA and promoter activities of human telomerase reverse transcriptase (hTERT) are stimulated

68 Expression of human telomerase reverse transcriptase (hTERT) catalytic subun

69 lects E6-enhanced transcription of the human telomerase reverse transcriptase (hTERT) catalytic subun

70 ce mechanism, ALT+ human fibroblasts require telomerase reverse transcriptase (hTERT) for tumor forma

71 optical methods to measure changes in human telomerase reverse transcriptase (hTERT) gene expression

72 The endogenous human telomerase reverse transcriptase (hTERT) gene is repress

73 The human telomerase reverse transcriptase (hTERT) gene is repress

74 s to and regulates the activity of the human telomerase reverse transcriptase (hTERT) gene promoter.

75 e ectopic expression of telomerase via human telomerase reverse transcriptase (hTERT) gene transfecti

76 life span, telomerase, was modified by human telomerase reverse transcriptase (hTERT) gene transfer t

77 so by transcriptionally activating the human telomerase reverse transcriptase (hTERT) gene, which enc

78 Transcriptional activation of the human telomerase reverse transcriptase (hTERT) gene, which rem

79 G-quadruplexes in the promoter of the human telomerase reverse transcriptase (hTERT) gene.

80 BV and three HPV integrations into the human telomerase reverse transcriptase (hTERT) gene.

81 s (DCs) transfected with mRNA encoding human telomerase reverse transcriptase (hTERT) have been shown

82 increased mRNA expression of CSF1R in human telomerase reverse transcriptase (hTERT) immortalized hu

83 e we report that ectopic expression of human telomerase reverse transcriptase (hTERT) in BMSSCs exten

84 of endogenous human telomerase RNA (hTR) and telomerase reverse transcriptase (hTERT) in HeLa cervica

85 in reaction (RT-PCR) for expression of human telomerase reverse transcriptase (hTERT) in mediastinal

86 to knock down factors cooperating with human telomerase reverse transcriptase (hTERT) in the immortal

87 onal conversion, whereas expression of human telomerase reverse transcriptase (hTERT) induces it.

88 Human telomerase reverse transcriptase (hTERT) is also often o

89 The transcriptional activation of human telomerase reverse transcriptase (hTERT) is an important

90 mechanisms governing expression of the human telomerase reverse transcriptase (hTERT) is important fo

91 Human telomerase reverse transcriptase (hTERT) is localized to

92 The human telomerase reverse transcriptase (hTERT) is nearly unive

93 Human telomerase reverse transcriptase (hTERT) is overexpresse

94 Human telomerase reverse transcriptase (hTERT) is overexpresse

95 s of the active full-length isoform of human telomerase reverse transcriptase (hTERT) may be expresse

96 analyses showed that leptin increased human telomerase reverse transcriptase (hTERT) mRNA expression

97 Although Tax impaired induction of human telomerase reverse transcriptase (hTERT) mRNA in respons

98 ,25(OH)(2)VD(3) decreases the level of human telomerase reverse transcriptase (hTERT) mRNA, the catal

99 Human telomerase reverse transcriptase (hTERT) plays a key rol

100 to show that FTSECs immortalized with human telomerase reverse transcriptase (hTERT) plus SV40 large

101 sid for enhanced tumor transduction, a human telomerase reverse transcriptase (hTERT) promoter for tu

102 The human telomerase reverse transcriptase (hTERT) promoter has be

103 s in the regulation of the activity of human telomerase reverse transcriptase (hTERT) promoter in res

104 al system, we recently showed that the human telomerase reverse transcriptase (hTERT) promoter induce

105 tly demonstrated that E6 activates the human telomerase reverse transcriptase (hTERT) promoter via a

106 l replication, is under control of the human telomerase reverse transcriptase (hTERT) promoter.

107 omerase activity without alteration of human telomerase reverse transcriptase (hTERT) protein express

108 Telomerase reverse transcriptase (hTERT) represents an a

109 ing network consistent with a model of human telomerase reverse transcriptase (hTERT) repression in A

110 unction mutations in the TEN-domain of human telomerase reverse transcriptase (hTERT) that disrupt th

111 expressed transcriptional regulator of human telomerase reverse transcriptase (hTERT) that is targete

112 established that hTR remains bound to human telomerase reverse transcriptase (hTERT) throughout all

113 a gene (pRb) and ectopic expression of human telomerase reverse transcriptase (hTERT) to immortalize

114 e we used retroviral overexpression of human telomerase reverse transcriptase (hTERT) to immortalize

115 Upregulation of human telomerase reverse transcriptase (hTERT) transcription a

116 of Bmi-1 in MECs led to activation of human telomerase reverse transcriptase (hTERT) transcription a

117 The human telomerase reverse transcriptase (hTERT) utilizes a temp

118 tor, and immortalized HAECs containing human telomerase reverse transcriptase (hTERT) were compared f

119 atalytic component of human telomerase human telomerase reverse transcriptase (hTERT), and colonies w

120 of p53, transcriptional activation of human telomerase reverse transcriptase (hTERT), and degradatio

121 f human telomerase, telomerase RNA (hTR) and telomerase reverse transcriptase (hTERT), are recruited

122 iated by the induced overexpression of human telomerase reverse transcriptase (hTERT), has permitted

123 The catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), is overexpress

124 ng cyclin-dependent kinase (Cdk) 4 and human telomerase reverse transcriptase (hTERT), resulting in c

125 nk between HMGA2 and the regulation of human telomerase reverse transcriptase (hTERT), the catalytic

126 Human telomerase reverse transcriptase (hTERT), the catalytic

127 Expression of human telomerase reverse transcriptase (hTERT), the catalytic

128 h the transcription and translation of human telomerase reverse transcriptase (hTERT), the catalytic

129 We present evidence that normal and human telomerase reverse transcriptase (hTERT)-immortalized hu

130 Here we characterize the response of human telomerase reverse transcriptase (hTERT)-immortalized no

131 We show here that human telomerase reverse transcriptase (hTERT)-immortalized pr

132 ressor pathways in NHUC and to express human telomerase reverse transcriptase (hTERT).

133 cted with a retroviral vector encoding human telomerase reverse transcriptase (hTERT).

134 e expression of its enzymatic subunit, human telomerase reverse transcriptase (hTERT).

135 or telomere synthesis, which is catalyzed by telomerase reverse transcriptase (hTERT).

136 rmal human fibroblast (NHF) expressing human telomerase reverse transcriptase (hTERT).

137 he human telomerase catalytic subunit, human telomerase reverse transcriptase (hTERT).

138 onents, human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT).

139 induction of the telomerase component human telomerase reverse transcriptase (hTERT); T cell activat

140 ein catalytic component of telomerase [human telomerase reverse transcriptase (hTERT)] are required f

141 n of the telomerase catalytic subunit [human telomerase reverse transcriptase (hTERT)] expression abr

142 Human telomerase reverse transcriptase (hTERT; the catalytic p

143 is the transcriptional upregulation of human telomerase reverse transcriptase, hTERT, and the resulta

144 l of the telomerase catalytic subunit [human telomerase reverse transcriptase, (hTERT)].

145 n of the telomerase catalytic subunit (human telomerase reverse transcriptase; hTERT) in human activa

146 Human telomerase reverse transcriptase (hTRT) is preferentiall

147 1delta) blocks primary ciliogenesis in human telomerase reverse transcriptase immortalized retinal pi

148 orm of CDK4 or knockdown of p16 in the human telomerase reverse transcriptase-immortalized NPE cell l

149 In human telomerase reverse transcriptase-immortalized NPE cells,

150 n of TRF2 expression in MNs and knock-out of telomerase reverse transcriptase in NPCs increased their

151 g the catalytic subunit of telomerase (human telomerase reverse transcriptase) in primary human mamma

152 sentation of a universal self-tumor antigen, telomerase reverse transcriptase, in human tumor cells d

153 be mediated through POT1/TRF2 and via human telomerase reverse transcriptase inhibition through JNK

154 The telomerase protein component TERT (telomerase reverse transcriptase) interacts with BRG1 (a

155 The introduction of the telomerase reverse transcriptase into the target lines e

156 The template for telomerase reverse transcriptase is within the RNA subun

157 the gene encoding its catalytic subunit, the telomerase reverse transcriptase, is established as the

158 hTERT, the human telomerase reverse transcriptase, is highly expressed in

159 s well as the effect that over-expression of telomerase reverse transcriptase may have on the replica

160 ted the 3-prime untranslated region of human telomerase reverse transcriptase mRNA and decreased its

161 HIF is sufficient to induce telomerase reverse transcriptase mRNA and telomerase act

162 ability of 1,25(OH)(2)D(3) to decrease human telomerase reverse transcriptase mRNA and to suppress ov

163 f IRF-4 results in decreased levels of TERT (telomerase reverse transcriptase) mRNA and telomerase ac

164 s and in carcinoma progression, an inducible telomerase reverse transcriptase (mTert) allele was cros

165 ation of slowly cycling ISCs marked by mouse telomerase reverse transcriptase (mTert) expression that

166 tation and telomere dysfunction [produced by telomerase reverse transcriptase (mTERT) gene knockout].

167 The enzyme telomerase reverse transcriptase (mTert) regulates telom

168 ein (GFP), driven by the promoter for murine telomerase reverse transcriptase (mTert), which is a nec

169 We therefore generated mouse telomerase reverse transcriptase (mTert)-GFP-transgenic

170 oding a 4-hydroxytamoxifen (4-OHT)-inducible telomerase reverse transcriptase-oestrogen receptor (TER

171 perature-sensitive large T antigen and human telomerase reverse transcriptase (OSEtsT/hTERT).

172 of four genetic alterations, including human telomerase reverse transcriptase overexpression, bypass

173 protein/TRAIL fusion protein from the human telomerase reverse transcriptase promoter (designated Ad

174 Myc E-box-mediated transactivation and human telomerase reverse transcriptase promoter activity, in a

175 em TTS (TTF1 gene under the control of human telomerase reverse transcriptase promoter and human surf

176 In this study telomerase reverse transcriptase promoter elements clone

177 te that Pyk2 is capable of driving the human telomerase reverse transcriptase promoter, resulting in

178 telomerase domain-complementation assays for telomerase reverse transcriptase protein (TERT) and RNA

179 s of two essential components, the catalytic telomerase reverse transcriptase protein (TERT) and the

180 te within its integral RNA subunit (hTR) and telomerase reverse transcriptase protein (TERT) to accom

181 The telomerase reverse transcriptase protein TERT has recent

182 erves to repress the production of the human telomerase reverse transcriptase protein.

183 to assemble telomerase enzymes with variant telomerase reverse transcriptase proteins.

184 The specialized telomerase reverse transcriptase requires a multidomain

185 The expression of human telomerase reverse transcriptase restored telomerase act

186 Subsequently, annealing of the telomerase reverse transcriptase RNA-template (guide RNA

187 rentiation family), catalytic subunit of rat telomerase reverse transcriptase (rTERT), and proliferat

188 studies utilizing a combination of BRCA1 and telomerase reverse transcriptase small interfering RNAs

189 e first characterize the gene coding for the telomerase reverse transcriptase subunit PpTERT in P. pa

190 d advantages of the TRAIL gene and the human telomerase reverse transcriptase target, Ad/gTRAIL can b

191 to telomeres through an association with the telomerase reverse transcriptase TERT.

192 onucleoprotein telomerase, which comprises a telomerase reverse transcriptase (TERT) and a telomerase

193 ng telomeric repeats using an active site in telomerase reverse transcriptase (TERT) and an integral

194 elomerase, a ribonucleoprotein consisting of telomerase reverse transcriptase (TERT) and an integrall

195 DNA-interacting subunits other than telomerase reverse transcriptase (TERT) and telomerase R

196 ns two essential components for catalysis, a telomerase reverse transcriptase (TERT) and telomerase R

197 Telomerase reverse transcriptase (TERT) and telomerase R

198 Telomerase reverse transcriptase (TERT) and telomerase R

199 critical for catalytic activity, the protein telomerase reverse transcriptase (TERT) and telomerase R

200 Telomerase minimally comprises the catalytic telomerase reverse transcriptase (TERT) and telomerase R

201 ' ends of linear chromosomes, using a unique telomerase reverse transcriptase (TERT) and template in

202 its essential for catalysis in vitro are the telomerase reverse transcriptase (TERT) and the telomera

203 mally consisting of a protein subunit called telomerase reverse transcriptase (TERT) and the telomera

204 activity and levels of its catalytic subunit telomerase reverse transcriptase (TERT) are increased in

205 ic mutations in the promoter of the gene for telomerase reverse transcriptase (TERT) are the most com

206 telomerase complex is influenced more by the telomerase reverse transcriptase (TERT) binding of the C

207 ls immortalized by the ectopic expression of telomerase reverse transcriptase (TERT) can give rise to

208 nt insights to the noncanonical functions of telomerase reverse transcriptase (TERT) catalytic subuni

209 ve suggested that the core protein mammalian telomerase reverse transcriptase (TERT) component, toget

210 Telomerase reverse transcriptase (TERT) confers the cata

211 Differential regulation of telomerase reverse transcriptase (TERT) contributes to t

212 To perform DNA synthesis, the active site of telomerase reverse transcriptase (TERT) copies a templat

213 omerase RNA template, the active site in the telomerase reverse transcriptase (TERT) core, a TERT N-t

214 lete single-repeat synthesis requires only a telomerase reverse transcriptase (TERT) core.

215 in lung fibrosis, we examined the effects of telomerase reverse transcriptase (TERT) deficiency in a

216 the overexpression of myocardin (MYOCD) and telomerase reverse transcriptase (TERT) enhanced the sur

217 Reactivation of telomerase reverse transcriptase (TERT) expression enabl

218 Reactivation of telomerase reverse transcriptase (TERT) expression is fo

219 been previously shown that expression of the telomerase reverse transcriptase (TERT) gene extends the

220 ating mutations occur in the promoter of the telomerase reverse transcriptase (TERT) gene in 66% of m

221 required for the transactivation of a silent telomerase reverse transcriptase (TERT) gene in exponent

222 , and point mutations in the promoter of the telomerase reverse transcriptase (TERT) gene increase te

223 is of B-cell lymphoma DNA confirmed that the telomerase reverse transcriptase (TERT) gene promoter is

224 Point mutations in the telomerase reverse transcriptase (TERT) gene promoter oc

225 risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (TERT) gene that encode

226 find a germline deletion in intron 3 of the telomerase reverse transcriptase (TERT) gene that predis

227 tudy, the role of Smad3 in the inhibition of telomerase reverse transcriptase (TERT) gene transcripti

228 ty is characterized by the expression of the telomerase reverse transcriptase (TERT) gene, suggesting

229 Differential regulation of telomerase reverse transcriptase (TERT) genes contribute

230 ed variants of human telomerase RNA (hTR) or telomerase reverse transcriptase (TERT) have exploited i

231 somatic acquisition of promoter mutations in telomerase reverse transcriptase (TERT) in blood leukocy

232 mplate boundary definition and high affinity telomerase reverse transcriptase (TERT) interaction.

233 Telomerase reverse transcriptase (TERT) is an essential

234 While telomerase reverse transcriptase (TERT) is conserved in

235 ue activity in the catalytic protein subunit telomerase reverse transcriptase (TERT) of telomerase.

236 e downstream network in mice null for either telomerase reverse transcriptase (Tert) or telomerase RN

237 arrow carrying heterozygous mutations in the telomerase reverse transcriptase (TERT) or the telomeras

238 nations of defined tumor-expressed antigens, telomerase reverse transcriptase (TERT) or TRP-2, and VE

239 ct somatic single-nucleotide variants in the telomerase reverse transcriptase (TERT) promoter and iso

240 Mutations in the human telomerase reverse transcriptase (TERT) promoter are the

241 We aimed to evaluate the occurrence of telomerase reverse transcriptase (TERT) promoter mutatio

242 The telomerase reverse transcriptase (TERT) promoter, an imp

243 Integrations in the telomerase reverse transcriptase (TERT) promoter/enhance

244 genes, including MYC transactivation of the telomerase reverse transcriptase (TERT) promoter; and in

245 somes and consists of two main subunits: the telomerase reverse transcriptase (TERT) protein and an a

246 daka and fugu TRs, when assembled with their telomerase reverse transcriptase (TERT) protein counterp

247 ue TR-binding domain (TRBD) in the catalytic telomerase reverse transcriptase (TERT) protein, integra

248 teraction between the CR4-CR5 domain and the telomerase reverse transcriptase (TERT) protein.

249 Transcriptional reactivation of telomerase reverse transcriptase (TERT) reconstitutes te

250 of telomerase-associated proteins other than telomerase reverse transcriptase (TERT) remain ambiguous

251 Here, using telomerase reverse transcriptase (Tert) reporter mice, w

252 activity by repressing the catalytic subunit telomerase reverse transcriptase (TERT) through negative

253 e that facilitates the subsequent binding of telomerase reverse transcriptase (TERT) to TER.

254 ize telomeric repeats, the catalytic subunit telomerase reverse transcriptase (TERT) uses the RNA sub

255 novel alternatively spliced (AS) variants of telomerase reverse transcriptase (TERT) were identified,

256 ver, tumorigenesis-associated genes IGF2 and telomerase reverse transcriptase (TERT) were overexpress

257 vitro with only the telomerase RNA (hTR) and telomerase reverse transcriptase (TERT), additional comp

258 -occurrence of mutations in the promoter for telomerase reverse transcriptase (TERT), along with BRAF

259 on of the catalytic component of telomerase, telomerase reverse transcriptase (TERT), alters sensitiv

260 s a ternary complex of telomerase RNA (TER), telomerase reverse transcriptase (TERT), and the essenti

261 sion of the catalytic subunit of telomerase, telomerase reverse transcriptase (TERT), as ectopic expr

262 ase RNA and a catalytic protein subunit, the telomerase reverse transcriptase (TERT), as well as seve

263 RNA (TR) or the catalytic protein component telomerase reverse transcriptase (TERT), cause the genet

264 subunit of telomerase, known generically as telomerase reverse transcriptase (TERT), exhibits signif

265 Regulator of telomere length-1 (RTEL1) and telomerase reverse transcriptase (TERT), genes involved

266 P. tetraurelia telomerase catalytic subunit, telomerase reverse transcriptase (TERT), has been cloned

267 s required for telomere maintenance, such as telomerase reverse transcriptase (TERT), have been found

268 Remarkably, with only binding sites for telomerase reverse transcriptase (TERT), minimized hTR a

269 ically organized by the components, i.e. the telomerase reverse transcriptase (TERT), telomerase RNA

270 often determined by the expression level of telomerase reverse transcriptase (TERT), the catalytic s

271 s exhibiting dysregulated growth may express telomerase reverse transcriptase (TERT), the dual functi

272 endent mutations within the core promoter of telomerase reverse transcriptase (TERT), the gene coding

273 omponents have been identified thus far: the telomerase reverse transcriptase (TERT), the telomerase

274 g an internal RNA template and a specialized telomerase reverse transcriptase (TERT), thereby maintai

275 on of the catalytic component of telomerase, telomerase reverse transcriptase (Tert), which is essent

276 Among 6,835 cancers, 73% expressed telomerase reverse transcriptase (TERT), which was assoc

277 onents, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT).

278 s using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT).

279 , using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT).

280 Cancer cells depend on transcription of telomerase reverse transcriptase (TERT).

281 chanistically, ASA treatment upregulates the telomerase reverse transcriptase (TERT)/Wnt/beta-catenin

282 plicative senescence, via down-regulation of telomerase reverse transcriptase (TERT); telomere dysfun

283 an stem and cancer cells express telomerase [telomerase reverse transcriptase (TERT)] in an effort to

284 ted the expression of the catalytic subunit (telomerase reverse transcriptase [TERT]) but had no effe

285 , called motif 3, in the catalytic domain of telomerase reverse transcriptase, that is crucial for te

286 east three principal subunits, including the telomerase reverse transcriptase, the telomerase RNA (TE

287 rostate-specific Ag (PSA) as well as against telomerase reverse transcriptase, the tumor-specific CTL

288 alter the overall stability or expression of telomerase reverse transcriptase, these rare genetic dis

289 NA, which in turn directs the binding of the telomerase reverse transcriptase to form the functional

290 Telomerase reverse transcriptase (TRT) is a tumor-associ

291 ked with a homology model of the Tetrahymena telomerase reverse transcriptase (tTERT) to characterize

292 ntains two essential components: Tetrahymena telomerase reverse transcriptase (tTERT), the catalytic

293 sing tissue reconstruction techniques; human telomerase reverse transcriptase was required for cells

294 nt evidence that the overexpression of human telomerase reverse transcriptase was sufficient to exten

295 The catalytic subunit, telomerase reverse transcriptase, was expressed in human

296 ficient mutations in TERT, the gene encoding telomerase reverse transcriptase, we asked whether resto

297 xpressed c-kit, interleukin-31 receptor, and telomerase reverse transcriptase when compared with cont

298 Furthermore, recombinant AREG induced telomerase reverse transcriptase, which appeared to be e

299 amplicon and also encompasses TERT, encoding telomerase reverse transcriptase, which plays a critical

300 TERT encodes telomerase reverse transcriptase, which together with th