ライフサイエンスコーパス: telomere sequence

1 T1-TPP1 proteins compared with the wild-type telomere sequence.

2 een the many G-quadruplex folds of the human telomere sequence.

3 chromosome immediately before the integrated telomere sequence.

4 in control DNA lacking the specific TG-rich telomere sequence.

5 estrict potential registrations of the added telomere sequence.

6 selectively bind and cleave the G-quadruplex telomere sequence.

7 rrangements confirmed the involvement of the telomere sequence.

8 unique Not I site from 0.7 kb of Tetrahymena telomere sequence.

9 LC1) to produce (TTAGGG)n repeats, the human telomere sequence.

10 hromosome termini without the use of natural telomere sequences.

11 h Form 1 and Form 2 adopted by natural human telomere sequences.

12 genome and/or in subgenomic targets such as telomere sequences.

13 f hTERT is required to promote elongation of telomere sequences.

14 otide, and several quadruplexes derived from telomere sequences.

15 225 or 180 kb long, containing both sod2 and telomere sequences.

16 tion, with two separate reactions amplifying telomere sequence and reference single copy gene (riboso

17 for its ability to form telomeres from human telomere sequence and to stably maintain long stretches

18 dentifying homology with previously reported telomere sequences and human repeat elements, gene seque

19 were derived from genic, retrotransposon, or telomere sequences and were not deleted from the donor s

20 Somatic cells generally do not maintain telomere sequences, and these cells become senescent in

21 sm demonstrated that spectra from the native telomere sequence are characteristic of a G-quadruplex s

22 ntramolecular G-quadruplexes formed by human telomere sequences are attractive anticancer targets.

23 gile telomeres in ALT cells, suggesting that telomere sequences are prone to replication problems.

24 Telomere sequences are subtly altered in est2-LT strains

25 tained a human Alu sequence at one end and a telomere sequence at the other end (Alu-CEN-M1-TEL and A

26 rosophila melanogaster, which lacks specific telomere sequences but nonetheless assembles terminal he

27 The G-quadruplex for the human telomere sequence consisting of a repeating d(TTAGGG) is

28 Telomere length (TL) was assessed as the telomere sequence copy number (T) compared to a single-c

29 X-ray crystallographic studies on the human telomere sequence d[AGGG(TTAGGG)3] revealed a unimolecul

30 G-quadruplex formed from the Oxytricha nova telomere sequence, d(G4T4G4), has been solved to 1.55 A.

31 Similarly, the telomere sequence did not alter the rate or distribution

32 The telomere sequence did not induce chromosome truncation a

33 In one orientation, the deposited telomere sequence did not interfere with expression of t

34 These results suggest that mutant telomere sequences elicit a checkpoint that is genetical

35 Recently, four-repeat human telomere sequences have been shown to form two different

36 and a related budding yeast with a degree of telomere sequence homology that is similar to human telo

37 Structures formed by human telomere sequence (HTS) DNA are of interest due to the i

38 hTRF (human TTAGGG repeat factor) binds the telomere sequence in vitro and localizes to telomeres cy

39 ed human telomere and several modified human telomere sequences in potassium-containing solutions.

40 ssettes on both arms show instability of the telomere sequences in S.cerevisiae at a frequency of app

41 tered so that telomerase adds the vertebrate telomere sequence instead of the yeast sequence to the c

42 a suggest that the irregularity of the yeast telomere sequence is because of the template sequence of

43 lly, we show that a 48-nucleotide DNA with a telomere sequence is more susceptible to nuclease digest

44 Schizosaccharomyces pombe cells can survive telomere sequence loss by continually amplifying and rea

45 leotides were able to compete with the human telomere sequence oligonucleotide for binding to a speci

46 ermine the effects of a defined interstitial telomere sequence on chromosome instability, as well as

47 so suggest a plausible explanation why human telomere sequences predominantly form hybrid-I and hybri

48 um pH for the ligation reaction of the human telomere sequence ranges from 4.5 to 6.0.

49 ion forks at telomeres and internally placed telomere sequences, regardless of whether the telomeric

50 recombination event between the two pMAX-121 telomere sequences, resulting in a linear molecule.

51 The constructs contain 0.8 kb of human telomere sequence separated by a unique Not I site from

52 The characterization of unusual telomere sequence sheds light on patterns of telomere ev

53 rmal template boundary, resulting in altered telomere sequences, telomere shortening, and cellular gr

54 ccharomyces cerevisiae contains an irregular telomere sequence (TG1-3)n, which differs from the regul

55 cell division, whereas telomerase elongates telomere sequences to compensate for losses that occur w

56 osition on a chromosome is not necessary for telomere sequences to localize to the bouquet; and (c) b

57 We used quantitative PCRs and a telomere-sequence to single-copy-gene-sequence ratio met

58 thesizes the multikilobase repeating hexamer telomere sequence (TTAGGG)n at the ends of chromosomes.

59 ating that there is an internal array of the telomere sequence (TTAGGG)n in the PAR.

60 ic repeats (TMRs) that are identical to host telomere sequences (TTAGGG).

61 ngth, and less than the value found with the telomere sequence under conditions that inhibit quadrupl

62 Remarkably, the mutant telomere sequence was different from that of wild-type c

63 res or fused together after complete loss of telomere sequences) was observed within 26 hours of C-10

64 p us understand why the G-quadruplex forming telomere sequences were adopted by almost all eukaryotic

65 lex secondary structure, whereas the altered telomere sequences were devoid of these signatures.

66 Telomere sequences were quantified by real-time polymera

67 gh distant from the template, ensures proper telomere sequence, which in turn promotes proper assembl

68 mammalian cells that correlate interstitial telomere sequence with sites of spontaneous and radiatio

69 3 DNA-binding domain (Cdc13-DBD) binds these telomere sequences with high affinity (3 pM) and sequenc

70 Human telomere sequences with two phosphate groups, one each a