ライフサイエンスコーパス: template

1 genome editing without the need for a repair template.

2 ted from each study using a purpose-designed template.

3 de novo RdRp assay on a subgenomic ZIKV RNA template.

4 ctions leading to the recognition of the RNA template.

5 A strand using the complementary strand as a template.

6 GNT) arrays after removal of the photoresist template.

7 ls of single-crystal gold using silicon as a template.

8 nase (Ct-RIOK-2) crystal structure 4GYG as a template.

9 s reported data monthly using a standardized template.

10 control tract, were registered to the study template.

11 anded DNA breaks or provision of a donor DNA template.

12 ptase (TERT) uses the RNA subunit (TER) as a template.

13 e-stranded, but not single-stranded DNA as a template.

14 II C-terminal domain (CTD) and the chromatin template.

15 hermal oxidation of the sacrificial graphene template.

16 hat deviated from their respective naive QRS template.

17 ion by using a covalently attached, U-shaped template.

18 vesosomes from dewetting of double emulsion templates.

19 rent templates being prioritized over future templates.

20 to nucleate assembly and select for ordered templates.

21 by cation exchange of structurally distinct templates.

22 nthesis on both the endogenous and exogenous templates.

23 mplifies the preparation of roadblocking DNA templates.

24 180 degrees C, and calcination to remove the templates.

25 arly for targets that have no close homology templates.

26 blem for proteins that lack close homologous templates.

27 om various analogous and homologous function templates.

28 etwork of four length-segregated replicating templates.

29 opping approach from p38alpha MAPK inhibitor templates.

30 crystal size control due to the superlattice templates.

31 targets compared to using the best threading templates.

32 ly suppress DNA synthesis on UVB-damaged DNA templates.

33 e measurements were used without genioplasty templates.

34 A new method is based on liquid crystal templating.

35 binding inhibits the formation of duplex DNA templating.

36 In both structures, template 1-MeA rotates to the syn conformation but pairs

37 ously established in vivo population average templates; 2) used deformation fields obtained during op

38 of patients for whom the GP deactivated the template (33.6% [intervention] versus 27.8% [control]).

39 tion process utilizing the simple benzofuran template 7 as a starting point for a fragment growing ap

40 After removing NSE templates, a molecularly imprinted sensor was successful

41 ocking layer and using this high quality AlN template: a deep UV-LED device fabricated and showed a s

42 nction of the template turnover, wherein the template acts as the catalyst.

43 ybridization for full-length oligonucleotide-template alignments - thermoalignments - across the geno

44 This template allowed for simultaneous structural control of

45 translational neuroscience research, a brain template and an atlas are necessary.

46 nd strand synthesis of a single-stranded DNA template and generate millions of pair-wise combinations

47 e-graft-poly (acrylic acid) (HPC-g-PAA) as a template and was coated with PDA to construct a passivat

48 rds us with an exhaustive library of natural templates and free technologies to borrow, replicate, an

49 PCR assembly of DNA templates and in vitro transcription allow synthesis and

50 al sheep brain structures by segmenting both templates and nlTPMs; and 4) annotated and labeled these

51 the scope and limitations of liquid crystal templating and look out to where the technique may lead

52 rather than double-stranded breaks and donor templates) and offers potential improvements in efficien

53 structure and physiology of the plant as the template, and an integral part of the devices.

54 anowires (v-CuNWs) using electrosynthesis on templates, and their application as a cut-and-paste excl

55 uding hard-templating, soft-templating, self-templating, and multimethod combination synthesis.

56 , in the presence of chlorambucil as a model template (anticancer drug).

57 so shows a high C-->A error rate on 8-oxo-dG templates ( approximately 10(-4)).

58 Anion-templated aqueous self-assembly resulted in the formatio

59 Ridges and grooves of the template are 10 microm width and depth ranging from 1 to

60 ree to which the contents of the attentional template are individually unique and where those idiosyn

61 ntional synthetic methods without additional templates are introduced.

62 pare mesoporous FeS2 without the aid of hard template as an electrocatalyst for the hydrogen evolutio

63 The addition of different templates as instructions reveals that, while the outcom

64 ests, together with the kinetic study of the template assembly and disassembly, have been investigate

65 as bivalent biomolecular substrates for the templated assembly of a functional RNA structure.

66 In this work, the bottom-up template-assisted preparation of high-density lattices (

67 ) opposite the G (normal) or 8-oxoG(damaged) template base.

68 show that when (+)-cis-B[a]P-N (2)-dG is the templating base, the B[a]P moiety is in a non-solvent ex

69 Unique to the conventional template based Lewis acid/base activation methods, herei

70 instrumental to our second place ranking on Template Based Modeling (TBM) and Free Modeling (FM)/TBM

71 We report a template-based method, LT-scanner, which scans the human

72 t protein homo-oligomer structures either by template-based modeling using homo-oligomer templates se

73 Using template-based structural homology modeling, we now show

74 the second search), consistent with current templates being prioritized over future templates.

75 ferase Accessibility Protocol for individual templates-Bisulfite Genome Sequencing (MAPit-BGS) and nu

76 the template, for adding telomeric repeats, template boundary element (TBE), and pseudoknot, enclose

77 lian cells, bulky DNA adducts located in the template but not the coding strand of genes block elonga

78 merases are capable of bypassing a distorted template but they are generally considered inaccurate an

79 eveloped using bacterial ABC transporters as templates but these have low sequence similarity to CFTR

80 homology between the target gene and repair template, but does not require CtIP, RAD51, or RAD52.

81 Their laminar nature is not templated by an external surface, but likely reflects a

82 emonstrate the structure of T = 1 assemblies templated by biological soft materials as well as the ex

83 mational selectivity toward Cs-conformers is templated by the twofold coordination to Ag adatoms.

84 tigenic epitopes on an AAV serotype 1 capsid template can evade NAbs without compromising titer, tran

85 ever in cases where no homologous structural templates can be detected, fold recognition is a notorio

86 ropriate, evolutionarily-related, structural templates can be identified is often trivial and may eve

87 These diverse amyloid templates can now be extended as dynamic self-propagatin

88 In some circumstances, self-templating can fuel disease, but it also permits access

89 The rotaxanes were prepared by a templated clipping reaction and an X-ray crystal structu

90 ear intron-exon boundaries if the conversion template comes from outside the population.

91 tional theory, that a six-porphyrin nanoring template complex, with a diameter of 2.4 nanometres, is

92 t, possess uniform pores inheriting from the template comprised of a closely packed lattice of monodi

93 ely functionalized heterocyles from a single template constitutes a rare study in contemporary organi

94 recent progress, the nonenzymatic copying of templates containing mixed sequences remains slow and in

95 he polymeric shell while a wealth variety of template cores were tested using a reversible cross-link

96 he strength of these prestimulus expectation templates correlated with participants' behavioral impro

97 The simple, easy access to the template coupled with opportunities for the synthesis of

98 The tetragonal symmetry of the dianionic template creates a nanoscale version of the box weave.

99 mposite including bovine serum albumin (BSA) template Cu nanoclusters (CuNCs@BSA) and single-walled c

100 xing polymer precursors with block copolymer templates, curing at 140-180 degrees C, and calcination

101 zed [2 + 2 + 2] cycloaddition and subsequent template-directed cyclization via Yamamoto coupling.

102 zymatic steps: 5'-dRP lyase gap trimming and template-directed DNA synthesis.

103 hesis DNA polymerases in employing a protein-template-directed mechanism of DNA synthesis opposite un

104 Template-directed polymerization reactions enable the ac

105 owever, attempts to demonstrate enzyme-free, template-directed synthesis of nucleic acids have been l

106 ring RNA-DNA hybrid four-way junctions or by template-directed synthesis with a single-stranded DNA (

107 Clamps must be loaded onto primer-template DNA (ptDNA) by clamp loaders that open and clos

108 In "digital LAMP", small quantities of both template DNA and reagents are encapsulated within a drop

109 technology permits very efficient use of the template DNA as well as sequence reads, which are nearly

110 om both double- and single-stranded circular template DNA using specific primer pairs.

111 w and propensity to form G-quadruplex in non-template DNA, corroborating with all biochemically estab

112 ss the flexibility to bypass obstructions in template DNA.

113 d erythrocytes and suggest that insertion of templated DNA represents an additional mechanism of anti

114 strand is inhibited by the stability of the template duplex.

115 nthetic routes to halide perovskites and the templating effects of the organic cations allow for fine

116 polymerase (RNAP) is dislodged from the DNA template either at specific DNA sequences, called the te

117 this conformational switch might control DNA template engagement and release, modulating replisome pr

118 s in mechanical properties of the film after template extraction.

119 ino acid sequence through several structural templates, followed by local energy minimization.

120 Our study provides a template for attaining deeper understanding of antibody

121 Our study provides a template for attention-mediated laminar information proc

122 The role of the terpenoid cyclase as a template for catalysis is paramount to its function, and

123 -rich/G4 motif located on the lagging strand template for DNA replication and supports Pif1 function,

124 ts as a scaffold for virus assembly and as a template for genome transcription and replication.

125 These m826 properties offer a template for H7N9 vaccine immunogens, a promising candid

126 porous tellurium nanotubes as a sacrificial template for hierarchically porous 1D carbon nanotubes.

127 We present a template for how a similar course can be replicated at o

128 ence of plant chemical novelty, and offers a template for investigating the 300,000 non-model plant

129 ew approach to use Parylene C as a versatile template for patterning soft materials potentially appli

130 The template for reporting data from drowning research was r

131 This structural mechanism presents a template for signal transduction in sensor histidine kin

132 More generally, this work provides both a template for studies quantitatively investigating treatm

133 The nanoparticles can act as a template for the chemical growth of a metal layer to fur

134 nized as a privileged structure and a useful template for the design of novel compounds with potentia

135 The resulting network model can be used as a template for the integration of new hematopoietic differ

136 ee radical system is a potentially excellent template for the preparation of a set of appropriate ana

137 on of DNA ends to generate a single-stranded template for the recruitment of another tumour suppresso

138 the role of human attachment in providing a template for two-brain coordination.

139 the Drosophila embryo and larva and provide templates for cuticular structures involved in larval lo

140 indicate that they should provide versatile templates for developing inhibitors of protein-protein i

141 ntly than do other Envs and may be excellent templates for developing soluble immunogens.

142 or particle picking often use low-resolution templates for particle matching, making them susceptible

143 hesis of N-heteroaryl-fused vinyl sultams as templates for programming chemical reactions on vinyl su

144 armacological disparity provided the perfect templates for SAR investigation.

145 onstrating that these materials can serve as templates for selective self-assembly of molecules or na

146 for optoelectronic devices and ferroelastic templates for strain coupled artificial magnetoelectric

147 tations that are also present in attentional templates for target search.

148 mbining RNPs with transgene-containing donor templates for targeted gene addition has proven challeng

149 now be extended as dynamic self-propagating templates for the construction of even more complex func

150 ids could act as suitable organocatalysts or templates for the development of functional materials wi

151 eous polarization are extensively studied as templates for unique physical phenomena and in the desig

152 /pseudoknot domain (t/PK) which includes the template, for adding telomeric repeats, template boundar

153 Template-free fabrication of non-spherical polymeric nan

154 It is critical to develop a highly efficient template-free method for the automatic recognition of pa

155 the reaction kinetics enables the rational, template-free synthesis of ssDNA that can be used for a

156 based 3D monolith was established by using a template-free temperature-induced phase separation (TTPS

157 ong-range heteronuclear contacts for fibrils templated from a 1:1 mixture of (13)C- and (15)N-labeled

158 Graphene-templated growth of Mo2 C produces well-faceted, large-s

159 However, stoichiometric installation of this template has not been feasible in the absence of an appr

160 The two metal centres coordinated to this template have different roles: one reversibly anchors su

161 t spatial self-organization against physical template heterogeneity as a dominant driver of spatial p

162 ons that make any reaction in the absence of template highly unfavorable (most commonly by using a lo

163 polymeric network forms either uniform self-templated hollow spheres (HS) or hollow tubes (HT).

164 stwald ripening in the presence of molecular templates immobilised on glass beads (the solid-phase).

165 The template in control practices prompted GPs to ask the pa

166 ngle-stranded oligodeoxynucleotide HDR donor template in vitro.

167 ated onto the nanogel via a membrane vesicle templated in situ gelation process, whereas the redox-re

168 e template up-regulates the formation of two templates in a predictable manner.

169 detected as few as 20 copies of Ebola virus templates in both human serum and saliva and could be ad

170 edding sacrificial circular gelatin vascular templates in collagen, which were removed through temper

171 thod utilizes double-layer colloidal crystal templates in conjunction with site-specific electrochemi

172 to improve the construction of diffusion MRI templates in light of inter-subject differences.

173 ementary sizes and geometries may be used as templates in the cage forming reactions.

174 ligomeric alpha-synuclein species capable of templating in human cells and neurons.

175 from European blood donors revealed frequent templated inserts originating from transcribed genes tha

176 ating nuclease-encoding cassettes and repair templates into the plant genome.

177 s of FDA-approved kinase inhibitors based on templates involving other kinases.

178 the ribosome along the messenger RNA (mRNA) template is a key determinant of the rate and processivi

179 ligands through their influence on their DNA template is determined by a subtle interplay of DNA mech

180 The bottom template is found to play an important role in stabilizi

181 ase pairing between the RNA monomers and the template is observed at the extension site and at the ad

182 The template is precisely defined, processively copied, and

183 For that purpose a new hierarchical template is prepared.

184 es using Pluronic F127 as a thermoresponsive template is reported.

185 am epitaxy (MBE) on c-plane sapphire and GaN templates is described herein.

186 when the sequence identity between query and templates is reduced, while the I-TASSER-MR server is de

187 Freeze casting, also known as ice-templating, is a technique that has received considerabl

188 olds of proteins that do not have structural templates, it is necessary for reconstruction studies to

189 vel stimulant drugs by exploiting structural templates known to target monoamine transporters for dop

190 bsequent treatment with RNase H releases RNA-templated ligation products into solution for downstream

191 ere able to merge the existing maps to a new template map of olfactory networks with connections to a

192 terpreted by pattern recognition tools (i.e. template matching fingerprinting and scripting) providin

193 urrence and spatial distribution of TPPII by template matching.

194 conductor thin films via a simple and robust templated meniscus-guided coating method.

195 Zn(II) was also a viable templating metal.

196 For at least one template, minor improvements in assay repeatability are

197 P is prepared (polymerized) in presence of a template molecule, but unlike in traditional molecular i

198 h quenched in presence of Metronidazole as a template molecule..

199 Barcoding of DNA template molecules early in next-generation sequencing (

200 g stimulators for slippage at slippage-prone template motif sequence 3' of such 'slippage-stimulatory

201 tional base(s) compared to the corresponding template motif.

202 merase (for example, mTR(-/-) telomerase RNA template mutants) provide a model for investigating path

203 Particularly, we template nanorods from a mixture of superparamagnetic Zn

204 Our findings suggest that the harmonic template neurons in auditory cortex may play an importan

205 dy, we discovered a unique class of harmonic template neurons in the core region of auditory cortex o

206 Images of the template obtained by atomic force microscopy show that T

207 reconstruction-deconvolution" logic provides templates of progenitor cells' potentiating effects, and

208 uring translation due to defects in the mRNA template or translation machinery, leading to the produc

209 FRET) measurements on Cy3/Cy5-labeled primer-template (p/t) DNA constructs in the presence of gp32.

210 We report a protein-templated polymer self-assembly strategy for forming a s

211 d ribosomes iteratively served as a ruler to template precise, regularly spaced upstream mRNA cleavag

212 ses, fortuitous errors introduced during DNA template preparation and RNA transcription are sufficien

213 s considered to exert constraints to all DNA-templated processes, including base excision repair wher

214 d regulatory functions in all eukaryotic DNA-templated processes.

215 An essential part of TER is the template/pseudoknot domain (t/PK) which includes the tem

216 Product template (PT) domains from fungal nonreducing polyketide

217 We show that the templated reaction turnover is limited by the duplex dis

218 vel platform for fluorogenic oligonucleotide-templated reactions between peptide nucleic acid probes

219 level of signal amplification obtained from templated reactions is a function of the template turnov

220 t how TLS polymerases gain access to the DNA template remains poorly understood.

221 cleoproteins with single-stranded DNA repair templates results in precise and targeted DNA replacemen

222 Transperineal template saturation biopsy served as the standard of ref

223 template-based modeling using homo-oligomer templates selected from the protein structure database o

224 categories, including hard-templating, soft-templating, self-templating, and multimethod combination

225 y is regulated by nascent RNA sequences, DNA template sequences, and conserved transcription factors.

226 f different leaving groups, nucleobases, and templating sequences to uncover the factors that yield s

227 in which the invading DSB end and its donor template share a 108-base-pair homology region and the d

228 The template signposted GPs to follow National Institute for

229 ntration ratio of dNTPs specified by the RNA template slippage-prone sequence and its 5' adjacent bas

230 ntration ratio of dNTPs specified by the RNA template slippage-prone sequence and its 5' adjacent bas

231 divided into four categories, including hard-templating, soft-templating, self-templating, and multim

232 ich was advantageous over conventional metal templating solution methods in terms of reaction time an

233 ormalized to Montreal Neurological Institute template space.

234 tween thermal gradient velocity and chemical template spacing.

235 We identify promoter and template-specific effects on severity of gene expression

236 odes, invariant linker sequences and modular template-specific primers to allow for the simultaneous

237 data suggest that the following base on the template strand dictates the addition of the mutated bas

238 tes DNA polymerase I to successfully inhibit template strand extension.

239 on', whereby transferring information from a template strand in the presence of its complementary str

240 t intercalate into the growing duplex as the template strand is copied into XNA.

241 Uniquely, the nvRNAP recognizes the template strand of its promoters and is capable of speci

242 preferentially removes DNA lesions from the template strand that block translocation of RNA polymera

243 articular, where and when TLS occurs on each template strand.

244 promoter opening and trapping of the DNA non-template strand.

245 bind to and unbind from transiently exposed template strands during DNA synthesis.

246 n, we develop an electrochemical sacrificial-template strategy to fabricate hollow Co3 O4 microtube a

247 The novel self-templated strategy, including sequential anion- and cati

248 For the self-templating strategy, a number of unconventional syntheti

249 r ferrocene (Fc) unit supported by ultraflat template-stripped Au and contacted by a eutectic alloy o

250 Here, we report that certain RNA template structures and G-rich sequences, ahead of diver

251 prediction due to factors such as inadequate template structures.

252 I)4L6 cages was synthesized through iron(II)-templated subcomponent self-assembly of 2-formylpyridine

253 ods which are applicable for imprinting food templates, summarize the recent progress in using MIPs f

254 human genome, our model detects thousands of template switch events during the evolution of human and

255 rangement and used this to study the role of template switch events in the origin of short mutation c

256 Although many of these are consistent with a template switch mechanism previously proposed for bacter

257 The local template switch process can create numerous complex muta

258 ing promotes an unanticipated lagging-strand template-switch mechanism during replication.

259 ays, which involve translesion synthesis and template switching (TS), are activated by the ubiquityla

260 We devised a generalized mutation model of template switching during replication that extends exist

261 by end joining or by microhomology-mediated template switching, the latter forming complex tandem du

262 ynthesis and subsequent bypass by error-free template switching.

263 lusive in mammals, enabling damage bypass by template switching.

264 Coupled with our previously developed templated syntheses of dibenzo crown ethers, this protoc

265 g macrocycles, is constructed using an anion template synthetic methodology.

266 The template system included a cutting guide and a pair of r

267 -acyl E-hydrazone acts as a hydrogen bonding template that directs the assembly of a benzylic amide m

268 deally would be carried out with nucleosomal templates that are assembled with customized core histon

269 mbed between PBI dimer pairs and accordingly template the folding of even-membered PBI macrocycles in

270 ure, J. Stoddart describes how being able to template the formation of mechanically interlocked molec

271 materials as confinement reaction vessels to template the synthesis of new nanosheet structures.

272 lloidal particle deposition on (sacrificial) templates, the amphiphilicity driven self-assembly of na

273 For the control group without templates, the largest RMSDs were 2.63 mm in superoinfer

274 boroxole functional monomer bound the sugar templates through cis-1,2-diol, cis-3,4-diol, and trans-

275 xide) (PEO) single crystals were used as the template to direct the crystallization of block copolyme

276 as support to load MNPs and as a sacrificial template to grow MOFs.

277 le-stranded DNA (dsDNA), which serves as the template to guide DSB repair.

278 e uniform microchannels can be utilized as a template to guide the assembly of Au nanoparticles, form

279 o plastid transformation provides a rational template to implement plastid transformation in related

280 This provides a template to investigate the gating of eukaryotic neurotr

281 hanging nanostructures from an aluminum tube template to polydimethylsiloxane (PDMS) via atomic layer

282 tures are mechanically robust and can act as templates to host metallic nanoparticles such as gold an

283 equence-specific nucleases (SSNs) and repair templates to plant cells.

284 rom templated reactions is a function of the template turnover, wherein the template acts as the cata

285 Instruction with a single template up-regulates the formation of two templates in

286 s monitoring XNA synthesis on a self-priming template using high-resolution melting (HRM) fluorescent

287 to first quantify the amount of SNPs on the templates using a two-channel fluorescence measurement.

288 oxide (ITO) substrate via a block copolymer template was developed for highly sensitive and selectiv

289 Recently, liquid crystal templating was also realised in water.

290 observed in the X-ray structure of ToxT as a template, we designed ten novel compounds that inhibit t

291 Using gamma-MSH as a template, we developed a peptide, [Leu(3), Leu(7), Phe(8

292 beacon architecture that masks the catalytic template, we show that this methodology can be used for

293 cyclic inosine 5'-diphosphate ribose (cIDPR) template were synthesised.

294 The plant's structure acts as a physical template, whereas the plant's biochemical response mecha

295 ive triplex DNA bonds enable parent-daughter templating, while in the second species, triplex binding

296 cleavage and the efficient delivery of donor template with adeno-associated virus (AAV).

297 and was made deep enough to grow a thick AlN template with high crystal quality and very few threadin

298 In this study, a photoresist template with well-defined contact hole array was fabric

299 ts show that our method yields diffusion MRI templates with cleaner fiber orientations and less artif

300 efficient copying of a variety of short RNA templates with mixed sequences.