ライフサイエンスコーパス: tenascin

1 ressed the extracellular marker, cytotactin (tenascin).

2 th localized expression of both versican and tenascin.

3 nd third strand in the beta-sandwich protein tenascin.

4 ing and promotes expression of scleraxis and tenascin.

5 third fibronectin type III domain from human tenascin.

6 third fibronectin type III domain from human tenascin.

7 nchymal condensation genes and deposition of tenascin.

8 Mutants of the tenascin 8-mer construct exhibit the same change in stab

9 tial deposition of the matricellular protein tenascin, a marker of active remodeling, was higher in h

10 onally, cell survival assays determined that tenascin and L1 Ab-treated cell suspensions yielded more

11 th myofibroblast formation and deposition of tenascin and procollagen I.

12 active for the extracellular matrix molecule tenascin and that treatment with the ototoxic antibiotic

13 ns known to be involved in adhesion, such as tenascins and integrins.

14 yaluronic acid and glycoproteins such as the tenascins and link proteins to form the matrix scaffold.

15 lectin domain that mediate interactions with tenascins and other extracellular-matrix proteins.

16 he extracellular matrix molecule tenascin-C (tenascin) and an antibody (Ab) to the cell adhesion mole

17 levels of extracellular matrix (versican and tenascin) and chemokine (BDFN, CCL5, CXCL5, and CXCL16)

18 High expression of collagen, fibronectin, tenascin, and alpha2 integrin was detected in the TGF-be

19 llular matrix proteins, including collagens, tenascin, and fibronectin.

20 al changes in the expression of fibronectin, tenascin, and laminin.

21 f extracellular matrix proteins: collagen I, tenascin, and periostin.

22 LAST ACTIVATING PROTEIN, COLLAGEN 1 TYPE A1, TENASCIN, and SOD3 expression in PTC MSCs compared to Th

23 that of its modulators pleiotrophin, NrCAM, tenascin, and the chondroitin sulfate proteoglycans, sug

24 In contrast, the production of decorin, tenascins, and fibromodulin markedly increased.

25 In vitro, both tenascin- and L1 Ab-treated cultures doubled the number

26 In contrast to the culture results, tenascin- and L1 Ab-treated mesencephalic grafts did not

27 Fibronectin and tenascin are large extracellular matrix proteins that in

28 conditions (3 microl of 3,000 cells/microl), tenascin augmented grafted THir neuron survival.

29 Cells that express tenascin begin to recover after about 2 weeks and are th

30 C promotes growth of axons if they express a tenascin-binding integrin, particularly alpha9beta1.

31 termined the expression of Ets-1, MMP-9, and tenascin by bronchial fibroblasts activated ex vivo.

32 ed the expression of the profibrotic factors tenascin C (TNC) and connective tissue growth factor (CT

33 Tenascin C (TNC) is a matricellular glycoprotein whose e

34 catenin signaling led to marked induction of tenascin C (TNC), an established promoter of cancer meta

35 of multiple metastasis effectors, including Tenascin C (Tnc), Jagged1 (Jag1), and Epiregulin (Ereg).

36 ranscriptional regulation of the ECM protein tenascin C (Tnc), which was necessary and sufficient for

37 metastasis-initiating ability by expressing tenascin C (TNC).

38 ), mapped within the gene coding sequence of Tenascin C (TNC).

39 ctive tissue growth factor (Ctgf, P = 0.04), tenascin C (Tnc, P = 0.035), Collagen Ialpha1 (Col1a1, P

40 CD44, tenascin C and fibrillin-1 mRNA levels were reduced by 4

41 s such as SPARC, thrombospondin 1 and 2, and tenascin C and X subserve important functions in extrace

42 ation of thick fibronectin fibrils, to which tenascin C colocalized.

43 We conclude that tenascin C contributes to the generation of a stem cell

44 ltured on osteo-mimetic surfaces coated with tenascin C exhibited enhanced adhesion and colony format

45 Here, we report that tenascin C is expressed in the bone endosteum and is ass

46 Tenascin C is highly expressed in the SVZ, and transgeni

47 21-associated differentiation in wdSCCs; yet tenascin C retention in connective tissue extracellular

48 ssed in the SVZ, and transgenic mice lacking tenascin C show delayed acquisition of the EGF receptor.

49 ha-smooth muscle actin were reduced, whereas tenascin C was increased, suggesting that P15-1 promoted

50 remodeling such as MMP-9, procollagen-3, and tenascin C were observed in all acute eczematous lesions

51 and media-lumen ratio and overexpression of tenascin C, an extracellular matrix glycoprotein that co

52 Bone matrix markers (biglycan, COL1A1, tenascin C, and fibronectin) and low-density lipoprotein

53 ges in netrin 4, fibroblast growth factor 2, tenascin C, collagen 1, meprin 1-alpha, and meprin 1-bet

54 Total levels of tenascin C, collagen type XII, and CD44 mRNA were increa

55 nipin reduced the levels of collagen type I, tenascin C, elastin and versican.

56 ey cellular regulators, such as EGFR, HSP70, Tenascin C, Frizzled-5, Patched-1, and Delta-like 1.

57 SCCs exhibited increased NF-kappaB and novel tenascin C, indicative of elevated rigidity; yet despite

58 including VEGF, IL-6, VEGF-C, HB-EGF, CTGF, tenascin C, integrin alpha5, and Eph receptor A2.

59 of proangiogenic genes, such as osteopontin, tenascin C, KGF, angiopoietin, HIF-1alpha, and PDGFRbeta

60 , vimentin, discoidin domain receptor 2, and tenascin C, markers of fibroblasts and components of the

61 he desmoplastic extracellular matrix protein tenascin C, suppressing tumor outgrowth, and improving h

62 llular deposits of eosinophil peroxidase and tenascin C, the effects not seen with placebo.

63 taining the fibronectin type III domain D of tenascin C, the long NC3 isoform of collagen type XII, t

64 For cyclinD1, fibulin 2, tenascin C, TIMP1, and aquaporin-4, correlations were si

65 ulation of the extracellular matrix protein, tenascin C, which affords a scaffold for VSMC migration.

66 p21 loss, elevated NF-kappaB expression and tenascin C-associated rigidity, with p-Mypt1 inactivatio

67 Tenascin C-deficient mice also have altered numbers of C

68 a correlation of IL-17+ T cell numbers with tenascin C-expressing cells and MMP-9+ eosinophils was a

69 ctor SOX4 and extracellular matrix component tenascin C.

70 ascular endothelial growth factor (VEGF) and tenascin C.

71 (+)) preceded K14.ROCK(er)-mediated (p-Mypt1/tenascin C/rigidity) malignant conversion.

72 top 10 results (collagen, type III, alpha-1; tenascin C; collagen, type VI, alpha-3; thrombospondin 2

73 Tenascin-C (encoded by Tnc) is an extracellular matrix g

74 e utilized the extracellular matrix molecule tenascin-C (tenascin) and an antibody (Ab) to the cell a

75 Tenascin-C (TN) is an extracellular matrix protein that

76 Enhanced expression of tenascin-C (TN-C) at the invasive edges of glioblastoma

77 Tenascin-C (TN-C) is an extracellular matrix (ECM) prote

78 Tenascin-C (TN-C) is expressed in embryogenesis, tissue

79 To address this question, we focused on tenascin-C (TN-C), a stromal extracellular matrix glycop

80 icipates in network formation, we focused on tenascin-C (TN-C), an extracellular matrix (ECM) protein

81 PDGF-BB also stimulates the expression of tenascin-C (TN-C), an extracellular matrix glycoprotein

82 vation of FAK and cellular interactions with tenascin-C (TN-C).

83 tified the extracellular matrix glycoprotein tenascin-C (TNC) as an important regulator of ENCC devel

84 pattern of the extracellular matrix molecule tenascin-C (Tnc) in the developing mouse olfactory bulb

85 Tenascin-C (TNC) is a highly conserved matricellular pro

86 Tenascin-C (TNC) is a mechano-regulated, morphogenic, ex

87 Tenascin-C (Tnc) is an extracellular matrix protein (ECM

88 Tenascin-C (TNC) is highly expressed in melanoma; howeve

89 r mPIN used the extracellular matrix protein Tenascin-C (TNC) to inhibit T-cell receptor-dependent T-

90 Here we provide evidence that tenascin-C (TNC), an extracellular matrix protein promin

91 Tenascin-C (TnC), an extracellular matrix protein, is tr

92 ral S100 proteins, including Fibronectin and Tenascin-C (Tnc), in primary lung tumors and associated

93 Tenascin-C (TNC), overexpressed in invasive growths, has

94 or alpha-smooth muscle actin (alpha-SMA) and tenascin-C (TNC).

95 y HIV-1-neutralizing protein in breast milk, Tenascin-C (TNC).

96 ctin (fnFN10) and the 3rd FN-III domain from tenascin-C (tnFN3) have 27% sequence identity and the sa

97 Syndecan-4 is also required for tenascin-C action.

98 Inhibition of syndecan-4 function suppresses tenascin-C activity and overexpression of syndecan-4 cir

99 stains in the rodent heart demonstrated that tenascin-C also colocalizes with EPCs homing to sites of

100 ie, production of collagen, fibronectin, and tenascin-C and accumulation of myofibroblasts).

101 ronment consisting of the highly upregulated tenascin-C and chondroitin sulfate proteoglycans (CSPGs)

102 ith matrices representative of transitional (tenascin-C and fibronectin) and differentiated environme

103 nts of this dynamic matrix, hyaluronic acid, tenascin-C and fibronectin, differentially direct cellul

104 ograft model of advanced human osteosarcoma, tenascin-C and its receptor integrin alpha9beta1 were de

105 The functional importance of stromal Tenascin-C and S100A4(+) fibroblast-derived VEGF-A in me

106 In this way, tenascin-C and syndecan-4 work together to control fibro

107 d in the developing brain: the glycoproteins tenascin-C and tenascin-R and the chondroitin sulfate pr

108 ta1- and FGF-2-induced de novo expression of tenascin-C and the downregulation of alpha3(IV) collagen

109 alpha7beta1 integrin mediates a response to tenascin-C and the first to demonstrate a functional rol

110 M molecules and growth factors, particularly Tenascin-C and VEGF-A.

111 Levels of tenascin-C are elevated in SSc skin biopsy samples, and

112 s performed and led to the identification of tenascin-C as a candidate protein.

113 valuate the contribution of the glycoprotein tenascin-c as a key mediator of smooth muscle cell growt

114 Together, our data highlight the role of tenascin-C as a microenvironmental regulator of cardiac

115 Thus, we have identified tenascin-C as a novel endogenous activator of TLR4-media

116 These results identify tenascin-C as an endogenous danger signal that is upregu

117 Our study revealed midkine, CYR61, and tenascin-C as endogenous substrates for KLK7.

118 the physiologically relevant presentation of tenascin-C as hexabrachion, and suggesting an increase i

119 ype mice or mice with a targeted deletion of tenascin-C by assessing cell maturation, cytokine synthe

120 The effects of tenascin-C combined with its location around the wound b

121 PGE(2) but more PGI(2) and expressed reduced tenascin-C compared with wild-type cells.

122 The region of tenascin-C containing only alternately spliced fibronect

123 Tenascin-C deficiency resulted in minor structural diffe

124 -C, and osteopontin, revealed that MMP-9 and tenascin-C demonstrated reduced expression both in vitro

125 C-AR modified cells aggregated to cells in a tenascin-C expressing stem cell niche model better than

126 PGE(2) and augmentation of PGI(2) attenuate tenascin-C expression and vascular smooth muscle cell pr

127 showed both retention of alpha9 integrin and tenascin-C expression at the anterior stromal-epithelial

128 Among these cells, tenascin-C expression is most highly induced in activate

129 nregulated both TGF-beta1- and FGF-2-induced tenascin-C expression, ROCK inhibition was found to down

130 after vascular injury, in part by regulating tenascin-C expression.

131 pathologic remodeling with aberrant Prx1 and Tenascin-C expression.

132 eased proliferating cell nuclear antigen and tenascin-C expression.

133 To determine the importance of tenascin-C in cardiac neovascularization, we used an est

134 diated induction of procollagen type III and tenascin-C in isolated cardiac fibroblasts was dependent

135 cts, interstitial deposition of collagen and tenascin-C in the remodeling myocardium was markedly red

136 ults illuminate how tumor cell deposition of tenascin-C in the tumor microenvironment promotes invasi

137 te how the extracellular matrix glycoprotein tenascin-C in the tumor microenvironment promotes invasi

138 aim of this study was to examine the role of tenascin-C in this cell type.

139 n in vivo in mice, and addition of exogenous tenascin-C induces cytokine synthesis in explant culture

140 ia of individuals with rheumatoid arthritis, tenascin-C induces synthesis of proinflammatory cytokine

141 Functionally, tenascin-C inhibits cardiac endothelial cell spreading a

142 Tenascin-C is a large extracellular matrix glycoprotein

143 Tenascin-C is an arthritogenic extracellular matrix glyc

144 Tenascin-C is an extracellular matrix molecule that driv

145 Tenascin-C is an extracellular matrix protein that regul

146 We show that tenascin-C is anti-adhesive for retinal pigmented epithe

147 The inhibitory effect of tenascin-C is circumvented by downstream activation of R

148 This demonstrates for the first time that tenascin-C is essential for postnatal cardiac angiogenic

149 Tenascin-C is expressed transiently during wound repair

150 These data demonstrate that tenascin-C is important in DC-mediated polarization of T

151 position of the extracellular matrix protein tenascin-C is part of the reactive stroma response, whic

152 Here we show that tenascin-C is produced by type-B cells and forms a layer

153 Tenascin-C levels and tumor uptake were studied in a var

154 Cells surrounded by a fibrin-FN+tenascin-C matrix are unable to induce matrix contractio

155 to facilitate colonization, whereas stromal Tenascin-C may provide protection from apoptosis.

156 SMA, vimentin, and tenascin-c mRNAs were decreased by 60%, 40%, and 49%, re

157 A in metastasis was established by examining Tenascin-C null mice and transgenic mice expressing Cre

158 association of the alpha7beta1 integrin with tenascin-C peptides containing the VFDNFVLK sequence but

159 utonomous signaling mechanism explaining how tenascin-C promotes cancer cell migration in the tumor m

160 Tenascin-C promotes growth of axons if they express a te

161 Intra-articular injection of tenascin-C promotes joint inflammation in vivo in mice,

162 Analysis of human coronary thrombi revealed tenascin-C protein expression colocalized with the endot

163 Cells on fibrin-FN+tenascin-C redistribute their actin to the cell cortex,

164 f the provisional matrix, we have found that tenascin-C regulates cell responses to a fibrin-FN matri

165 anding how the extracellular matrix molecule tenascin-C regulates neuronal growth.

166 se of MMPs was accompanied by an increase in tenascin-C release.

167 aling by competitive binding of fibulin-1 or tenascin-C represents a shared mechanism of adhesion mod

168 Mice lacking tenascin-C show attenuation of skin and lung fibrosis, a

169 Here we show that mice that do not express tenascin-C show rapid resolution of acute joint inflamma

170 we show that the regenerative ECM component tenascin-C significantly increases newt cardiomyocyte ce

171 Exogenous tenascin-C stimulates collagen gene expression and myofi

172 Here we map three sites within tenascin-C that directly and cooperatively interact with

173 EDGIHELFP(48)) resembles the sequence within tenascin-C to which the integrin alpha(9)beta(1) binds.

174 sis of PAH such as serotonin transporter and tenascin-C was elevated in distal arteries and had a hig

175 ar degeneration-affected Bruch's membrane is tenascin-C which we confirm is present at high levels in

176 ne signature identified five common targets: tenascin-C(TNC), matrix metalloprotease-2, collagen-6-A1

177 s for cell adhesion/motility (syndecan-4 and tenascin-C) and hyaluronan (HA) signaling.

178 ciated KLKs), whereas others (e.g. CYR61 and tenascin-C) could be digested by several KLKs.

179 nents (fibrillar type I and III collagen and tenascin-C) had no effect.

180 Tenascin-C, a matrix protein induced upon tissue damage

181 Induction of tenascin-C, a proproliferative and promigratory extracel

182 (EGFR) found within the EGF-like repeats of tenascin-C, an antiadhesive matrix component present dur

183 Tenascin-C, an extracellular matrix protein involved in

184 hed with vascular endothelial growth factor, tenascin-C, and activated matrix metalloproteinase-9, fa

185 transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls muscle cell behavio

186 We could validate phosphacan, tenascin-C, and L1-CAM as major LeX carrier proteins pre

187 n, matrix metalloproteinases (MMPs) 2 and 9, tenascin-C, and osteopontin, revealed that MMP-9 and ten

188 lly expresses neural cell adhesion molecule, tenascin-C, and other molecules.

189 regulated matricellular proteins TSP1 and 2, tenascin-C, and SPARC.

190 several MMPs, TGF-beta signaling molecules, Tenascin-C, and VEGF-A, while pro-fibrotic molecules, in

191 adhesion modulatory proteins, fibulin-1 and tenascin-C, both of which bind to the C-terminal heparin

192 infant but not the adult DM was positive for tenascin-C, fibrillin-1, SPARC, and laminin-332.

193 Here, we report that, like tenascin-C, fibulin-1 inhibits fibroblast spreading and

194 kers, including collagen types I and III and tenascin-C, fostered statistically significant cell alig

195 Dendritic cells that did not express tenascin-C, however, produced lower levels of inflammato

196 show dynamic spatial and temporal changes in tenascin-C, hyaluronic acid, and fibronectin ECM distrib

197 ed by expressing an integrin that recognizes tenascin-C, one of the components of glial scar tissue,

198 as occurs in the presence of the ECM protein tenascin-C, promotes a motile phenotype; FAK and Rho sig

199 nD to an eight amino acid sequence unique to tenascin-C, VFDNFVLK, and showed that the amino acids FD

200 Fibroblast response to fibulin-1, similar to tenascin-C, was dependent on expression of the heparan s

201 aptamer to the extracellular matrix protein tenascin-C, was prepared in fluorescent and radiolabeled

202 pha-smooth muscle actin (SMA), vimentin, and tenascin-c, were measured in archived human HCC tissues

203 Calcific leaflets also exhibit tenascin-C, which may facilitate inflammatory cell migra

204 model and showed that unlike wild-type mice, tenascin-C-/- mice fail to vascularize cardiac allograft

205 Tenascin-C-AR modified cells aggregated to cells in a te

206 stem cell (HSC) mimics were modified with a tenascin-C-AR to improve the homing of HSC after an auto

207 ted epithelial cells with alpha9 integrin, a tenascin-C-binding integrin, led to a large increase in

208 Using live-cell imaging, we found softer tenascin-C-coated substrates significantly enhanced migr

209 cells preferentially migrated and colonized tenascin-C-coated trabecular bone xenografts in a novel

210 Moreover, tenascin-C-null mice displayed ablated levels of interle

211 Dendritic cells derived from tenascin-C-null mice exhibited no defects in maturation;

212 dorsal root ganglia regenerated through the tenascin-C-rich dorsal root entry zone into the dorsal c

213 egulation of anti-adhesive molecules such as tenascin-C.

214 pha9beta1-mediated adhesion and migration on tenascin-C.

215 eractions between the aggrecan G3 domain and tenascin-C.

216 ggrecan as well as articular markers such as tenascin-C.

217 ed the presence of the target protein, human tenascin-C.

218 rite outgrowth by itself and also as part of tenascin-C.

219 ion of syndecan-4 circumvents the effects of tenascin-C.

220 on of proliferating cell nuclear antigen and tenascin-C.

221 ased EMT protein markers, SMA, vimentin, and tenascin-c.

222 levels under the control of the promoter for tenascin-C.

223 f age, there were fewer condylar superficial tenascin-C/Col1-positive cells and more numerous apoptot

224 co-localizing with the fibrillar fibronectin/tenascin-C/periostin structures that characteristically

225 of membrane and secreted proteins, including Tenascins, Cathepsin-B precursor, cystatin, and numerous

226 metry, toxicity, and response of (131)I anti-tenascin chimeric 81C6 for the treatment of lymphoma.

227 ce in the LIF-null animals including desmin, tenascin, Cox-2, bone morphogenetic protein (BMP)-2 and

228 on allergen-induced eosinophil accumulation, tenascin deposition (as a marker of repair and remodelli

229 cosal type I and III collagen expression and tenascin deposition was also observed in swimmers than i

230 including fibronectin, laminin, vitronectin, tenascin, elastin, fibrillin-1, microfibril-associated g

231 including fibronectin, laminin, vitronectin, tenascin, elastin, fibrillin-1, microfibril-associated g

232 monstrate that TNF-alpha increases MMP-9 and tenascin expression in bronchial fibroblasts via the tra

233 nd that it contributed to enhanced MMP-9 and tenascin expression.

234 TGF-beta1 and IL-13 also induced tenascin expression.

235 Tenascin-R (TN-R) is a member of the tenascin family of multidomain matrix glycoproteins that

236 We found that tenascin fragments that contain type III modules 3-5 bin

237 ) and TNfn3 (the third fnIII domain of human tenascin), have essentially the same backbone structure,

238 48 h skin biopsies as well as the numbers of tenascin immunoreactive cells at 48 h.

239 alpha-smooth muscle actin(+) myofibroblasts, tenascin immunoreactivity, and procollagen-I(+) cells 24

240 results in a nearly complete elimination of tenascin immunoreactivity.

241 decorin, versican, fibronectin, laminin and tenascin in ASM was quantified as fractional area and me

242 Fibronectin is a covalent dimer and tenascin is a hexamer.

243 Tenascin is an extracellular matrix glycoprotein that is

244 lphaPS2) integrin receptor and transmembrane tenascin ligand are both suppressively downregulated in

245 In conclusion, pretreatment with tenascin may prove beneficial to prevent anoikis in dilu

246 er, DLX regulates the expression of NCAM and tenascin, molecules that are important for feather bud i

247 ein, which preceded an increase in MMP-9 and tenascin mRNA.

248 ith direct injections of (131)I-labeled anti-tenascin murine 81C6 monoclonal antibody (mAb) into surg

249 matricellular proteins, such as osteopontin, tenascin or secreted protein acidic and rich in cysteine

250 s containing the complete 20-mer or a 12-mer tenascin peptide partially blocked phage binding to the

251 gic reaction and (b) shows that decreases in tenascin positive cells at 48 h correlates with reductio

252 ast to tendon-associated genes scleraxis and tenascin, present in the chordae tendineae.

253 Both MMP-9 and tenascin promoters contain an Ets binding site, suggesti

254 duced Ets-1, MMP-9, and, to a lesser extent, tenascin protein expression or activity.

255 ecreted protein acidic and rich in cysteine, tenascins), proteoglycans (eg, versican, syndecans, bigl

256 blast activation and expression of SMemb and tenascin provide evidence of continuous remodeling in th

257 Tenascin-R (TN-R) is a member of the tenascin family of

258 f chondroitin sulfate proteoglycans (CSPGs), tenascin-R (TN-R), hyaluronan (HA), and link proteins, s

259 e of the purified proteins was identified as tenascin-R (TNR) by mass spectrometric analysis.

260 w that the extracellular matrix glycoprotein tenascin-R (TNR) is produced in the granule cell layer o

261 ping brain: the glycoproteins tenascin-C and tenascin-R and the chondroitin sulfate proteoglycans bre

262 We focused on aggrecan, brevican, and tenascin-R as they are especially expressed in the matur

263 We have determined that tenascin-R associated with Purkinje cell bodies and thei

264 The expression of tenascin-R by oligodendrocytes and small interneurons in

265 Versican and tenascin-R colocalized in OLCs, and coimmunoprecipitatio

266 with beta1,4-linked GalNAc-4-SO(4), whereas tenascin-R in other regions of the cerebellum does not b

267 The cellular adhesion molecule tenascin-R is a multifunctional extracellular matrix com

268 tion of this unique sulfated carbohydrate to tenascin-R may serve to modulate its adhesive/anti-adhes

269 sed the effect of aggrecan, brevican, and/or tenascin-R on neurite outgrowth in vitro.

270 rotein expression of aggrecan, brevican, and tenascin-R throughout the rat brain utilizing immunohist

271 eceptors -1, -4, and -5, homer-1 and -2, and tenascin-R.

272 d alpha10 (collagen receptors) and alpha9 (a tenascin receptor).

273 The expression of MMP-9 and tenascin reflects disease activity in asthma and airway

274 etinal pigment epithelial cells to adhere to tenascin-rich wet age-related macular degeneration-affec

275 ctin type III domains from the human form of tenascin that exhibits approximately 1 kcal mol(-1) incr

276 perfamily, the third fnIII domain from human tenascin (TNfn3) and the tenth fnIII domain from human f

277 l in cross-linking aggrecan, hyaluronan, and tenascin to form extended protein networks found in tiss

278 between various fragments of fibronectin and tenascin to further characterize and localize the bindin

279 binds directly to Na(v)1.9/NaN and recruits tenascin to the protein complex in vitro.

280 The site on tenascin to which fibronectin binds has been localized t

281 ing Abs to TGF-beta as well as production of tenascin transcripts and protein product.

282 e if several potential ligands (fibronectin, tenascin, vitronectin, and osteopontin) were expressed d

283 thickness (CCT) of wild-type, TNC(-/-), and tenascin X (TNX(-/-)) knockout mice were measured.

284 Histocompatibility Complex (MHC) including: tenascin X (TNX); cytochrome P450, subfamily XXIA, polyp

285 like (FBG) domain of the matrix glycoprotein tenascin-X (TNX) interacts physically with the small lat

286 uctural level, detection of collagen XII and tenascin-X by immunogold labeling confirmed this finding

287 Tenascin-X deficiency in humans is associated with Ehler

288 Tenascin-X is a large extracellular matrix protein expre

289 Tenascin-X is a large extracellular matrix protein of un

290 man Ehlers-Danlos syndrome and suggests that tenascin-X is an essential regulator of collagen deposit

291 collagen-modifying enzyme, we suggested that tenascin-X might regulate collagen synthesis or depositi

292 Collagen type V, decorin, fibromodulin, and tenascin-X proteins were unaffected by the cross-link in

293 gen XII was found for the avian homologue of tenascin-X that in humans is linked to Ehlers-Danlos dis

294 and other extracellular proteins (periostin, tenascin-X).

295 gment with sequence identity to a peptide in tenascin-X, an extracellular matrix protein.

296 glycoprotein, serum amyloid P-component, and tenascin-X, were selected as promising examples of the u

297 omic symptoms and is linked to a mutation in tenascin-X.

298 ts of alpha1(IV) and alpha1(V) collagens and tenascin-X] and three peptides that increased (fragments

299 ygous mutation (T3257I) in the gene encoding tenascin XB (TNXB in 6p21.3).

300 polymorphisms on chromosome 6p21.3 at TNXB (tenascin XB)-FKBPL (FK506 binding protein like) [rs12153