ライフサイエンスコーパス: tenfold

1 of OmpR for its binding sites (greater than tenfold).

2 rature, as assessed through theta50 , varied tenfold.

3 le the overall reaction rate varies by about tenfold.

4 the rate of the oxidative folding more than tenfold.

5 and increases the number of O4+/GFAP+ cells tenfold.

6 s that from atomic fluorescence by more than tenfold.

7 ells augmented anti-dsDNA Ab secretion about tenfold.

8 was normal, but insulin levels were elevated tenfold.

9 ncentration range for topoisomerase activity tenfold.

10 ent cleavage rates of specific substrates by tenfold.

11 C CALMODULIN: transcripts increased five- to tenfold.

12 by hypotonic exposure increased p38 activity tenfold.

13 forskolin slowed GFP-AQP2 mobility by up to tenfold.

14 epair system, hHR23B stimulated XPC activity tenfold.

15 einases type 3 (TIMP-3) gene by greater than tenfold.

16 mediated GTP hydrolysis on Ran approximately tenfold.

17 ndogenous leptin levels are raised more than tenfold.

18 d cause the Km for tRNA to increase four- to tenfold.

19 olding but slowed the rate of folding nearly tenfold.

20 previously characterized nucleases more than tenfold.

21 ded--the capacity--can be enhanced more than tenfold.

22 timated to outnumber their bacterial prey by tenfold.

23 nnitol injection increased CNS gene delivery tenfold.

24 fferentiation increases hVPr-GFP(+) cells by tenfold.

25 Tenfold (1 log10) incremental increases in maternal HIV

26 set of their MI had an increase in mortality tenfold (13.79%) compared with patients without a recent

27 erindividual differences are often more than tenfold; a 'slow metabolizer' or 'low-responsive' indivi

28 By combining multiple designed mutations, a tenfold affinity improvement to 52 pM was engineered int

29 ctions peak after 15-20 min, but diminish by tenfold after 4 h.

30 ian 3'-UTR length has expanded approximately tenfold alongside an increased generation of alternative

31 7, and the average rate of cell death varied tenfold among regions.

32 e affinity of the head-tail interaction over tenfold and concomitantly repress the tail's regulatory

33 n (83%), but drives reporter gene expression tenfold and fivefold more effectively than those of rat

34 alf-maximal activation of Ca(2+)-ATPase were tenfold and fourfold higher, respectively, than mammalia

35 ChE improved genetic stability approximately tenfold and growth phase-specific productivity approxima

36 eability of AQP6 oocytes rapidly rises up to tenfold and is accompanied by ion conductance.

37 tem in insects, outnumbering nuclear genomes tenfold and representing all orders versus very few.

38 d the LPS-monocyte interaction by as much as tenfold, and depletion of sCD14 from the serum restored

39 squito populations have increased as much as tenfold, and mosquito communities have become two- to fo

40 , the resolution could be increased by up to tenfold, and the method could be extended to some other

41 t between nerve and adjacent tissue is up to tenfold, and useful contrast lasts up to 8 h.

42 ated that cholesterol feeding enhanced Apo B tenfold, Apo A-I fivefold but not Apo E in VLDL.

43 etection, while also increasing tumor uptake tenfold ( approximately 20% injected dose/g) under optim

44 level of Lck-GCaMP2 near the plasma membrane tenfold as compared with conventional GCaMP2.

45 y for phosphate of the D51N enzyme decreased tenfold as the concentration of Mg2+ increased.

46 orted across the epithelium and concentrated tenfold at the apical surface.

47 ediate, a 5'-abasic residue exerted an about tenfold attenuation on the 3' to 5' exonuclease efficien

48 ecombination/DNA repair activities three- to tenfold below wild type (or about 1000-fold above that o

49 tidylinositol (ECD-GPI) anchor approximately tenfold better than the same ectodomain on the wild-type

50 f a solid tumor, but was slowed greater than tenfold beyond 500 microm.

51 rn increased the rate of unfolding more than tenfold but had little effect on the rate of folding, wh

52 d rAAV-2-mediated gene transfer to the liver tenfold, but they did not affect transduction of skeleta

53 site, and the rate of cleavage is increased tenfold by a mutation associated with early-onset Alzhei

54 protein, which could be stimulated at least tenfold by an oligonucleotide carrying a strong enhancer

55 ase activity of isolated FliI was stimulated tenfold by bacterial (acidic) phospholipids, such that a

56 ty of the HMM preparation was activated over tenfold by calcium, indicating that the preparation cont

57 CINC-1 and MIP-2 increased nearly tenfold by Day 8 95% O(2) treatment versus air control.

58 of these matrices increased reversibly about tenfold by decreasing the valency of the bathing externa

59 th gamma-Al2O3 boosts the catalytic activity tenfold, by affecting the bonding between the reactant-d

60 found extensive persistence time variation (tenfold; coefficients of variation = 0.58-1.20) across c

61 (N6), increases in vitro secretion of FVIII tenfold compared with BDD-FVIII.

62 of these mutant tRNAs are reduced by two to tenfold compared with native tRNA(Gln), consistent with

63 ed with Fanconi anemia was reduced by nearly tenfold, compared to that observed in fibroblasts from n

64 y, which could be competitively blocked by a tenfold concentration of free cyclic RGD.

65 dulated by macroscale stretching, with up to tenfold concomitant increases in ellipticity.

66 Tenfold cross-validation showed 85.7% sensitivity, 60.7%

67 Tenfold cross-validation was used to train and test clas

68 Equivalently, every tenfold decrease in binding constant at constant salt an

69 omain, and removal of this domain leads to a tenfold decrease in lytic activity toward rabbit erythro

70 strength from 100 mM to 250 mM NaCl caused a tenfold decrease in the association rate while the disso

71 n with a proton resulted in an approximately tenfold decrease in the binding affinity.

72 ATFS-1 impairment reduced the mtDNA nearly tenfold, decreasing the total percentage to 7%.

73 ween both anti-CEA antibodies, despite their tenfold difference in affinity.

74 trand overlapping gene pairs show at least a tenfold difference in length, much larger than the lengt

75 x had a strong negative effect, predicting a tenfold difference in migration distances between low- a

76 uxurians, and Tripsacum dactyloides) reveals tenfold differences in abundance of the major satellite

77 r wet and dry conditions (corresponding with tenfold differences in B. tectorum biomass), and despite

78 that observed during waking and accelerated tenfold during slow-wave sleep.

79 ature increased, with preferences increasing tenfold during the hottest periods.

80 hat cells in the motile subpopulation have a tenfold enhanced likelihood of entering the K-state and

81 litting) via the applied gate voltage, and a tenfold enhancement of polaritonic over excitonic emissi

82 cence from the bulk and yields net more than tenfold enhancement of the fluorescence intensity.

83 om 15 s to 5 min increased the recovery time tenfold even when the glutamate concentration was held a

84 They prevent a tenfold excess in R8 photoreceptor cell specification.

85 e independent of T-helper cells occurs, with tenfold expansion of CD8+ T cells over a period of 5 day

86 ained, fortified products provided more than tenfold FA than (6S)-5-CH3-H4PteGlu.

87 consumption in this young clump is more than tenfold faster than in the host galaxy, displaying high

88 . the complex of FixL with FixJ, is at least tenfold faster than the phosphorylation of FixL without

89 found that the rate constant for ligation is tenfold faster than the rate constant for cleavage under

90 te of 1.1 x 10(7) s(-1) in the coil state is tenfold faster than the rate for a disordered peptide wi

91 triplet of the unfolded protein is more than tenfold faster than the rate observed for the native pro

92 isjoins a non-native interaction in P3 folds tenfold faster than the wild-type ribozyme.

93 aling endosome fuses to lysosomes sixfold to tenfold faster than when Coronin-1 is intact.

94 he Mg2+-dependent folding behavior, although tenfold faster.

95 rotrophic bacterial activity increased up-to tenfold following two days of dark incubations, once sea

96 in non-additive increases in affinity: up to tenfold for a hepta-alanine mutant.

97 Folding rates vary by tenfold for circularly permuted Bacillus subtilis RNase

98 with differences among accessions of almost tenfold for lycopene.

99 ith the wall mobility at high fields reduced tenfold from that at low fields.

100 ound to increase with increasing growth rate tenfold (from 0.17 to 1.7) in the presence, but only fiv

101 inhibit enzymatic activity with a magnitude tenfold greater than ProS, but can also chaperone subtil

102 ea centred at this location is approximately tenfold greater than that of the stapes.

103 by the FlhD(2)C(2)complex was approximately tenfold greater than the FlhC subunit alone, suggesting

104 IHF has a tenfold higher affinity for hmU-DNA without a consensus

105 without Zn2+ and showed that hPL has about a tenfold higher affinity for the hPRLR ECD1 than hGH.

106 nes expressing EGFR, most likely due to the >tenfold higher affinity of BTC-TX50.

107 fold higher than in 3-mo-old animals and was tenfold higher at 24 mo of age.

108 In contrast, tenfold higher dosages of leptin had no effect on body w

109 mutant p53 (143 val-->ala) required at least tenfold higher doses of adriamycin to down-regulate BRCA

110 f live births; the incidence of CHD is up to tenfold higher in human fetuses.

111 markably constant and low in the cytosol and tenfold higher in the matrix, mediates ADP/ATP exchange

112 revious work demonstrated that PGG/GGG has a tenfold higher Km value and 10(3)-fold reduced k(cat) re

113 thout a previous diagnosis have an estimated tenfold higher risk of a subsequent hematological cancer

114 but neutrophils have the ability to roll at tenfold higher shear stress in microvessels in vivo.

115 denervated neuropil to a peak that was about tenfold higher than control at 2-4 days, decreased betwe

116 P-GLUC excretion in bile of Mrp3-/- mice was tenfold higher than in Mrp3+/+ mice.

117 2.7 micrograms/ml of rFVIII in milk was over tenfold higher than in normal plasma.

118 ity of the enzyme for the FMR-1 SSC is about tenfold higher than it is for a control Watson-Crick pai

119 emerged that virus abundances are typically tenfold higher than microbial cell abundances.

120 ee positions, yet transposition on the ME is tenfold higher than on the OE in vivo.

121 tion lines that reveal a mutation rate about tenfold higher than previous indirect estimates and an e

122 tivity elicited by DC/TAT-TRP2 was three- to tenfold higher than that induced by DC/TRP2.

123 The CNR of IMR images was almost tenfold higher than that of FBP images.

124 At doses tenfold higher than that required to reduce hypersensiti

125 ainst fatal toxicity of IL-2 with IL-2 doses tenfold higher than the safely tolerated level in Spragu

126 These responses are five- to tenfold higher than the T-cell responses induced by the

127 ination inhibition antibody titres more than tenfold higher than those from the licensed inactivated

128 ications to the tomato genome at frequencies tenfold higher than traditional methods of DNA delivery

129 in the primary subject panel, explaining the tenfold higher variance found compared with that derived

130 fibronectin domains may require forces about tenfold higher.

131 the mitochondrial matrix, where [Mg(2+)] is tenfold higher.

132 pensated CH3NH3PbBr2.94Cl0.06 alloy has over tenfold improved bulk resistivity of 3.6 x 10(9) Omega c

133 This variant showed a tenfold improvement in catalytic efficiency (kcat/KM) re

134 voltage indicator exhibited an approximately tenfold improvement in sensitivity and speed over existi

135 riats with multiple loops or coils increased tenfold in a preparation of L-DNA-gp3-gp16 complexes.

136 termediate chain), has been duplicated about tenfold in a tandem array.

137 ages and found that proliferation increased tenfold in damaged utricles from the youngest neonates.

138 ry phases of the host response are more than tenfold in excess of previously suspected values.

139 naling include a reduction of up to five- to tenfold in IGF-stimulated PI 3-kinase activation, a fail

140 meiotic DSB formation, are elevated at least tenfold in spermatocytes lacking ATM.

141 protein bcl-x(L) was increased greater than tenfold in the mutant animals (P < .04), which can, at l

142 eraction of S1.MgADP.Pi with actin decreased tenfold in this range of osmotic pressure, suggesting th

143 t seeded and unseeded reactions by more than tenfold in vitro.

144 atment increased nectar production more than tenfold in wild-type plants, but nectar production was n

145 unt of calcium required to cause a transient tenfold increase in [Ca2+]i per unit volume) and calcium

146 .4 +/- 0.9 mV that shifted by 59.6 mV with a tenfold increase in [K(+)](o).

147 of contacts with antigen, as reflected by a tenfold increase in affinity, and one of these mutations

148 did not benefit RAG-1-/- mice, which had a > tenfold increase in bacteremia compared to controls.

149 metabolic engineering, we obtain a more than tenfold increase in bisabolene titers in Escherichia col

150 e, treatment with either Tc or IPTG led to a tenfold increase in CAT activity.

151 a 66% increase in the citation rate for each tenfold increase in Ci.

152 oxy terminus of Cre, resulting in a five- to tenfold increase in Cre activity.

153 thout loss of the COF structure, for which a tenfold increase in elasticity accompanies its demetalat

154 f responses complete in seconds and a nearly tenfold increase in electrical signal relative to those

155 oxia induced erythropoietin expression and a tenfold increase in erythropoietin receptor expression,

156 We also observed a tenfold increase in fluid output from the hydrothermal s

157 ants with enhanced beta-fucosidase activity (tenfold increase in k(cat)/K(M) in reactions with the no

158 o the histidine binding pocket, leading to a tenfold increase in Km for histidine in the pyrophosphat

159 leolin relocalization was concomitant with a tenfold increase in nucleolin-hRPA complex formation.

160 both USF-1 and USF-2 caused an approximately tenfold increase in reporter gene expression in Caco-2 c

161 omplete activation of sigmaF is induced by a tenfold increase in SpoIIE activity.

162 V40 nuclear localization sequences enabled a tenfold increase in the efficiency of neuronal editing i

163 ns in the floxed mice, which correlated with tenfold increase in the expression of cytokeratin19.

164 r technology and report herein that there is tenfold increase in the frequency of PDC-E2(159-167)-spe

165 yrophosphate exchange reaction, as well as a tenfold increase in the Km for tRNA in the aminoacylatio

166 of the Bcr/Abl transgene, and a greater than tenfold increase in the level of BCR/ABL protein.

167 ld (4.3 MPa in La3+ to 37 kPa in Na+) upon a tenfold increase in the matrix volume.

168 ing performance, leading to an approximately tenfold increase in the photocurrent at a bias of 0.23 V

169 d tomato fruits, and (iii) achieved an up to tenfold increase in total tocochromanol accumulation.

170 We found that a tenfold increase in urban size could result in an earlie

171 In neuroblastoma cells, a tenfold increase of concentration of Ba, Mg, and Ca give

172 eased affinity for huVkappa1 (B1kappa1) and >tenfold increased affinity for huVkappaIII (B1kappa3).

173 to form hydrogen bonds, and four- to almost tenfold increased likelihood to participate in formation

174 mice, but not single-mutant controls, showed tenfold-increased rolling velocities in a TNF-alpha-indu

175 han expected in the early 20th century, with tenfold increases from preindustrial levels by the early

176 an tissue-derived phospholipids, leading to >tenfold increases in the rate of fibrillogenesis.

177 is protein, called copy-up pi, allow four to tenfold increases of gamma ori plasmid DNA in vivo.

178 ng, but T18 phosphorylation weakened binding tenfold, indicating that phosphorylation of only T18 is

179 t seem to be affected by PB or BA treatment, tenfold induction of P-450 1A1 mRNA after BA treatment w

180 ong Chinese women, however, there has been a tenfold intergenerational reduction in smoking uptake ra

181 sulfonate, and the increase in fluorescence (tenfold) is accompanied by a blue shift in the band posi

182 yields high contrast and resolution up to a tenfold larger FOV.

183 emperatures, which accommodate the more than tenfold larger thermal expansion perpendicular to these

184 ectively as the wild-type proteinase but was tenfold less potent against [Asp30]proteinase.

185 The affinity of S195A for hirudin was only tenfold less than that of thrombin and the kinetic const

186 gradative activities of plant cells are only tenfold less than those reported for bacterial GTN degra

187 coordinates of [0.15, 0.29], representing a tenfold lifetime improvement over a conventional blue el

188 ift into the -1 frame are characterized by a tenfold longer pause in elongation compared to non-frame

189 BC-tPA persisted in the bloodstream at least tenfold longer than did that of free tPA.

190 from 6' sialyllactose, and has approximately tenfold lower affinity for N-glycolylneuraminic than for

191 hibits equal on-target cleavage activity but tenfold lower average off-target activity in human cells

192 p to explain why Shaker has an approximately tenfold lower conductance than its bacterial relatives.

193 nd 24 hr trough concentrations were at least tenfold lower in combination treatment and those of cycl

194 recombinant human TFIIA, possessed a nearly tenfold lower koff when bound to TATA.

195 ir in mitotic cells, being detected at about tenfold lower levels (per DSB) than during meiotic recom

196 ATF2(delta1-195) clones exhibited up to tenfold lower resistance to irradiation by either U.V. o

197 rticularly in wild-type cells which showed a tenfold lower survival than null cells.

198 T1, the K(m) of 1,2-1,6-arm is approximately tenfold lower than for 1,2-1,3-arm and 1,4-1,3-arm, and

199 nsensus sequence (Kd = 0.3 nM, approximately tenfold lower than for H' perfect duplex DNA).

200 eshifting from 3 to 6 %, an efficiency about tenfold lower than seen with the 11 bp construct.

201 with nucleotide diversity pi syn = 0.00017, tenfold lower than the autosomal region (pi syn = 0.0017

202 cific DNA with affinities only approximately tenfold lower than the native sequences.

203 Interestingly, these levels are four- to tenfold lower than those observed in failing human heart

204 ttenuated vaccines produced an approximately tenfold lower vaccine-associated viraemia compared to th

205 cells in the GI tract for 99mTc and 123I are tenfold lower; those for 131I are fivefold lower and tho

206 Strikingly, APOBEC3A-like samples have over tenfold more APOBEC-signature mutations than APOBEC3B-li

207 of hydralazine-induced hypotension contained tenfold more c-Fos-ir DNPI/VGLUT2 neurons than that of s

208 capture) protocol that provides greater than tenfold more contacts per cell than the previous method.

209 In one transformant there was five to tenfold more p53 than T-Ag. p53 was present in transform

210 pha,beta-methylene ATP (alpha,beta-mATP) was tenfold more potent than ATP while beta,gamma-methylene

211 of the new monoclonal antibodies are almost tenfold more potent than the recently described PG9, PG1

212 anifest a threefold larger diameter and have tenfold more primary processes than those of rodents.

213 placement synthesis was found to be at least tenfold more processive than non-displacement synthesis,

214 cofilin binding arises from an approximately tenfold more rapid association rate constant and an appr

215 nd promote oligonucleotide cleavage at least tenfold more rapidly than folding of the wild-type riboz

216 us in DNA), are stable in low salt and up to tenfold more resistant to DNase I digestion than when un

217 nt than the wild-type domain, allowing up to tenfold more sensitive detection of human Vkappa antibod

218 Our method detects tenfold more true HLA-A SNPs than previous analyses of t

219 within 40-fold and kinetic parameters within tenfold of wild-type antibody, indicating that residues

220 The half-lives of many mRNAs vary tenfold or more in response to cytokines, hormones, star

221 This was a tenfold or threefold mean increase in transplanted cell

222 which increase recombination frequency up to tenfold over conventional designs.

223 toward human thrombin is enhanced more than tenfold over that of desulfo-hirudin, suggesting that su

224 hereas SNP raised epitrochlearis cGMP levels tenfold (P < 0.001), neither in vitro contractile activi

225 aminicola resistant cultivar IP18292 with a ~tenfold peak at 9 h post inoculation.

226 orage monomeric anthocyanins declined almost tenfold, probably due to polymerization reactions and co

227 on with sequencing coverage falling within a tenfold range for a majority of all targets.

228 of these two transporter types varies over a tenfold range, depending on the organism.

229 taining glutamineH50 and lysineH52, showed a tenfold rate enhancement over wild-type.

230 ity, this altered tetrameric repressor has a tenfold reduced affinity for operator and greatly decrea

231 day 3 post inoculation is associated with a tenfold reduced lethality and neurotropism in mice.

232 ant also expresses Hsp101 in seeds, but at a tenfold reduced level, resulting in reduced thermotolera

233 in Arabidopsis, and demonstrated a more than tenfold reduction in miR159b transcription.

234 A data are noisy owing to a typical five- to tenfold reduction in precursor selectivity compared to d

235 n 7-2-7 heptamer pair mediated approximately tenfold repression.

236 ft PMAs were improved more than fourfold and tenfold, respectively, compared with coverslips or rigid

237 stly, the calculated reversal potential in a tenfold salt gradient (0.1:1M KCl) is 27.4(+/-1.3)mV (BD

238 out a 17-fold improvement in reliability and tenfold savings in time compared with other neuron recon

239 Tenfold serial dilutions of a cloned target were used as

240 Tenfold serial dilutions of the World Health Organizatio

241 We have demonstrated an up to tenfold serum-dependent increase of c-myc protein levels

242 Tenfold shotgun sequence coverage was obtained from the

243 nt streptavidin, traptavidin, with more than tenfold slower biotin dissociation, increased mechanical

244 2'-hydroxyl group from the ribose results in tenfold slower cleavage.

245 lf-splicing in optimal Mg2+ (>/= 150 mM) was tenfold slower, in part because of the existence of an e

246 p, reduced Ape1 degradation activity roughly tenfold, suggesting that the biological impact of certai

247 Both the tenfold symmetry and symmetry-broken decagonal (D) clust

248 X secretion at levels significantly higher (>tenfold) than those obtained with an archetypal ubiquito

249 ar-formation efficiency exceeds 50 per cent, tenfold that of clouds in the Milky Way.

250 agment magma at these depths, which is about tenfold the highest values previously measured in a mid-

251 The technology increases by tenfold the sensitivity of the traditional assays, and s

252 ms of the all-d peptide were recognized with tenfold to 100-fold greater affinities relative to the m

253 trates used, we observe rate enhancements of tenfold to 4,100-fold over the background, with catalyti

254 er site lowers the reporter gene activity by tenfold to a basal level.

255 the beta-strand lock increase activity about tenfold to a level comparable to other formins, suggesti

256 ected, hFIX serum levels increased more than tenfold to approximately 4 microg/ml, similar to normal

257 al nitrosyl(heme)hemoglobin levels increased tenfold to the micromolar range, and both measures were

258 ated PN concentrations, which decreased from tenfold to twofold over the same distance, but the spati

259 toward GAATTC is reconstituted by less than tenfold toward GAAUTC.

260 Remarkably, Met-misacylation increases up to tenfold upon exposing cells to live or non-infectious vi

261 ain 4-7% of the disease variance and up to a tenfold variation in interindividual risk.

262 200-fold and the Km for folate increased by tenfold versus the wild-type enzyme.

263 l trapping of imatinib was reduced more than tenfold when chloroquine is used simultaneously, which s

264 recruitment of these interneurons increases tenfold when they are excited by two pyramidal cells.

265 liner proximity and bird mortality increased tenfold when trawlers were not operating.

266 cond; however, T7 helicase slows down nearly tenfold when unwinding the strands of duplex DNA.

267 s of the longest closed time tauCL decreased tenfold, while the short and long open times increased f

268 ere significantly increased by approximately tenfold, with decreasing hydroxylation of the respective

269 nc increased CBF beta-SMMHC levels more than tenfold, with higher levels evident in Ba/F3 lines.

270 -area electron diffraction pattern along the tenfold zone axis was found to be different from other A