ライフサイエンスコーパス: teratocarcinoma

1 arget an aggressive tumor (grafted F9 murine teratocarcinoma).

2 peutic possibilities of targeting testicular teratocarcinoma.

3 ies glycolipid thought to be unique to human teratocarcinoma.

4 pe although it was derived from a testicular teratocarcinoma.

5 xd3-/- ES cell lines or to generate Foxd3-/- teratocarcinomas.

6 are also the cell of origin of multilineage teratocarcinomas.

7 he undifferentiated areas of the alpha5-null teratocarcinomas.

8 lecules was more disorganized in alpha5-null teratocarcinomas.

9 el formation both in ES cell cultures and in teratocarcinomas.

10 d ectopically into syngeneic mice to develop teratocarcinomas.

11 increased apoptosis observed in alpha5-null teratocarcinomas.

12 luripotent stem cells such as those found in teratocarcinomas.

13 at contemporary HK2 virions produced by some teratocarcinoma and breast cancer cell lines, as well as

14 CREB(DIEDML), activates transcription in F9 teratocarcinoma and PC12 cells even in the absence of pr

15 nd motivated re-examination of the cases for teratocarcinomas and liver cancer.

16 self-renewal, relate this to the biology of teratocarcinomas and offer testable hypotheses to expose

17 and in tumor cell lines PA-1 (human ovarian teratocarcinoma) and MCF-7 (human breast adenocarcinoma)

18 uman and murine germ cell tumors (testicular teratocarcinomas) and low in non-germ-cell tumors.

19 ussed evidence for a nonmutational origin of teratocarcinoma, and cited related claims in liver carci

20 ranscriptionally targeted gene expression to teratocarcinoma, and that evaluation in other flt-1-posi

21 plantation embryos, primordial germ cells or teratocarcinomas are currently unique in undergoing prol

22 TF(+/+), TF(+/-), and TF(-/-) teratomas and teratocarcinomas are indistinguishable.

23 Teratocarcinomas are tumors that arise from primordial g

24 17 and no other human chromosome on a mouse teratocarcinoma background.

25 ed Wnt-13 could modulate the histogenesis of teratocarcinomas by mediating interactions between sub-p

26 nge the enzyme specificity, we transfected a teratocarcinoma cell line (2102Ep) with vectors encoding

27 euron-like cells (NT2N) derived from a human teratocarcinoma cell line (NTera2/D1) with drugs that de

28 since overexpression of SRF in the embryonal teratocarcinoma cell line F9, which normally expresses l

29 n, in virus-like particles isolated from the teratocarcinoma cell line NCCIT, there is significant ac

30 The human teratocarcinoma cell line NTera 2 (NT2) can be induced t

31 Here we report that in the teratocarcinoma cell line NTera2, p53 is subject to lysi

32 In PA-1, another teratocarcinoma cell line of human origin that has no or

33 ly induced during the differentiation of the teratocarcinoma cell line P19 along a neuronal lineage a

34 Inhibition of myocardin function in the teratocarcinoma cell line P19CL6 prevented differentiati

35 (hNT) neurons derived from the NTera2 (NT2) teratocarcinoma cell line were shown to remain postmitot

36 NTera-2/D1 (NT2) is a human teratocarcinoma cell line which can be cultured as a div

37 These results are confirmed in the F9 teratocarcinoma cell line, a model for retinoic acid-ind

38 Furthermore, upon differentiation of a teratocarcinoma cell line, the expression of an active L

39 In the F9 murine teratocarcinoma cell line, this DR5 RARE is required for

40 tivity of DNMT1, -2, -3a, and -3b in a mouse teratocarcinoma cell line.

41 , and to microcell hybrids made with a mouse teratocarcinoma cell line.

42 We have characterized two murine teratocarcinoma cell lines and find no evidence that end

43 ine zipper motif and has been found in human teratocarcinoma cell lines and some tumor cells.

44 , we describe properties of p40 in the human teratocarcinoma cell lines NTera2D1 and 2102Ep.

45 mplicated in the tumorigenicity of the human teratocarcinoma cell lines PA-1 that contain an activate

46 F9 teratocarcinoma cell lines, carrying one or two disrupte

47 detected in six human breast epithelial and teratocarcinoma cell lines.

48 , in association with LINE-1 RNA(s) in human teratocarcinoma cell lines.

49 n, and cytokeratins in a human trophoblastic teratocarcinoma cell, HT-H.

50 Human teratocarcinoma cells (GH cells), which produce HERV-K p

51 F9 embryonic stem cell-like teratocarcinoma cells are widely used to study early emb

52 formation of primitive endoderm in mouse F9 teratocarcinoma cells as does the stimulation of the Fri

53 nhibits cellular proliferation of testicular teratocarcinoma cells by two possible mechanisms, p53-de

54 d (RA) treatment of Jun-deficient, mouse F9, teratocarcinoma cells causes the induction of c-jun expr

55 Human NT2 teratocarcinoma cells differentiate into neuron-like NT2

56 Teratocarcinoma cells ex vivo in tissue culture are also

57 p53-mediated responses in murine testicular teratocarcinoma cells exposed to the drug.

58 Because F9 embryonic teratocarcinoma cells form primitive endoderm after stab

59 ssociated A3243G mutant mtDNA into human NT2 teratocarcinoma cells frequently causes mtDNA loss.

60 ras oncogene-transformed PA-1 human teratocarcinoma cells have abundant AP-2 mRNA but, parad

61 or growth, B16F10 melanoma and F9 testicular teratocarcinoma cells have been implanted in C57BL/6J an

62 Previous experiments using human teratocarcinoma cells indicated that p40, the protein en

63 duced differentiation of human Ntera 2 (NT2) teratocarcinoma cells into neuron-like cells (NT2-N cell

64 sis that the p53 protein in undifferentiated teratocarcinoma cells is transcriptionally inactive and

65 Testicular teratocarcinoma cells rarely contain mutations in TP53,

66 Overexpression of ZPK in NTera-2 human teratocarcinoma cells results in inhibition of PKA induc

67 Interestingly, Wnt3a stimulation of F9 teratocarcinoma cells results in reduced Dishevelled met

68 Genes activated in mouse totipotent F9 teratocarcinoma cells solely by activation of the Rfz1 c

69 terizing the DNA damage response of isogenic teratocarcinoma cells that differ only in their level of

70 RA induces differentiation of F9 mouse teratocarcinoma cells toward neurons as well as extraemb

71 These teratocarcinoma cells undergo p53-mediated apoptosis in

72 ransfer of single human chromosomes to mouse teratocarcinoma cells will allow examination of developm

73 Cisplatin treatment of teratocarcinoma cells with a wild-type p53 gene resulted

74 93 kidney, SK-N-AS neuroblastoma, and NT2/D1 teratocarcinoma cells with NF2 promoter-luciferase chime

75 Differentiation of these teratocarcinoma cells with retinoic acid results in a ma

76 retinoic acid-induced differentiation of F9 teratocarcinoma cells, a model of epiblast-to-primitive

77 ariety of cell types, including F9 embryonic teratocarcinoma cells, and can influence axial pattern f

78 enzyme is inducible by retinoic acid in P19 teratocarcinoma cells, and we report the cloning from P1

79 ion microscopy as a GFP-fusion protein in F9 teratocarcinoma cells, Bex3 localized, along with concen

80 In mouse teratocarcinoma cells, canonical Wnts that inhibit heart

81 of p53 by DNA damage results in apoptosis of teratocarcinoma cells, whereas MDM2, encoded by a p53-re

82 In embryonic stem cell-like F9 teratocarcinoma cells, which are widely used to study re

83 NA, as it is in the p40 RNP complex found in teratocarcinoma cells.

84 ated expression of the murine Hoxa-1 gene in teratocarcinoma cells.

85 gregation-independent myogenic conversion of teratocarcinoma cells.

86 s in p53-wild-type cells but not in p53(-/-) teratocarcinoma cells.

87 lls and depleted NT2 (human neuron-committed teratocarcinoma) cells.

88 n average, an 8-fold decrease in alpha5-null teratocarcinomas compared with control tumors.

89 visualize PE migration in vitro using the F9 teratocarcinoma derived embryoid body outgrowth system a

90 However, alpha5-null teratocarcinomas displayed less undifferentiated tissue

91 gen-activated protein kinase p38 in mouse F9 teratocarcinoma embryonal cells.

92 Treatment of mouse teratocarcinoma F9 cells with all-trans-retinoic acid (R

93 Furthermore, treatment of F9 murine teratocarcinoma (F9) cells with 10(-6) M all-trans-retin

94 stem cells to form teratocarcinomas in mice; teratocarcinoma formation was reconstituted by reexpress

95 Teratocarcinomas formed by EGFR-deltakinase-expressing E

96 ng endothelium of ES-cell origin occurred in teratocarcinomas from heterozygous Lmo2-lacZ ES cells bu

97 and risk of forming unwanted tissues or even teratocarcinomas have yet to be fully assessed.

98 ) cells or fully differentiated human neuron teratocarcinoma (hNT cells).

99 In human embryonic teratocarcinoma (hNT2) cells transfected with the human

100 the ability of embryonic stem cells to form teratocarcinomas in mice; teratocarcinoma formation was

101 nger for nonseminomas, and for teratomas and teratocarcinomas in particular (N = 58; CT: OR, 1.63; 95

102 compromised immunodeficient mice to produce teratocarcinomas in which Ry1R expression is absent.

103 ance of this Lmo2 expression was assessed in teratocarcinomas induced in nude mice by subcutaneous im

104 era-2N neurons, but not the parental NTera-2 teratocarcinoma line, decarboxylate [2-(15)N]glutamine t

105 library prepared from the human neuronogenic teratocarcinoma line, NTera2, and cloned a 2373 nucleoti

106 transgene expression levels were detected in teratocarcinoma lines, correlating with levels of flt-1

107 ed in which mice bearing i.p. murine ovarian teratocarcinoma (MOT) were injected i.p. with reporter g

108 Testicular teratocarcinomas never contain p53 gene mutations even t

109 In the case of teratocarcinomas, normal germinal stem cells have the po

110 tinoic acid induced differentiation of human teratocarcinoma NT2 cells in association with attenuatio

111 neuronal differentiation in the NTera2 human teratocarcinoma (NT2) cell line.

112 (Genbank accession number DQ516383) in human teratocarcinoma (NT2) cells that differentiate into hNT

113 G promotes neuronal differentiation of human teratocarcinoma NTERA-2 cells.

114 mor cell lines derived from the embryoblast (teratocarcinoma) or from other lineages failed to do so.

115 also detected in Tera-1, a cell line of the teratocarcinoma origin.

116 In mouse teratocarcinoma (P19) cells expressing betaAPP695 or bet

117 ously purified recombinant ATX, based on the teratocarcinoma sequence, retains these same activities.

118 morphogen-induced promotion of F9 embryonic teratocarcinoma stem (F9 stem) cells to primitive endode

119 gs cause the differentiation of F9 embryonic teratocarcinoma stem cells into parietal endoderm, an ep

120 Medium conditioned by mouse F9 teratocarcinoma stem cells stably transfected to express

121 hogen-induced decline in Gialpha triggers F9 teratocarcinoma stem cells to progress to primitive endo

122 p26A1 RAREs in F9 embryonal carcinoma cells (teratocarcinoma stem cells) during RA treatment.

123 h human myeloid leukemia and mouse embryonic teratocarcinoma stem cells, either RA-suppressed CAK pho

124 iption factor expressed at high levels in F9 teratocarcinoma stem cells, embryonic stem cells, and ot

125 immortalized fibroblasts (Balb/c3T3), and F9 teratocarcinoma stem cells.

126 ulate specific subsets of target genes in F9 teratocarcinoma stem cells.

127 RA-resistant myeloid leukemia and embryonic teratocarcinoma stem RARalpha(-/-) cells.

128 onal carcinoma (EC) cell line derived from a teratocarcinoma that differentiate exclusively into post

129 and the growth of TF-deficient teratomas and teratocarcinomas were analyzed.

130 alpha5-null-derived teratocarcinomas were significantly smaller than the wil

131 ted region) of DRD2 in NT2 (neuron-committed teratocarcinoma, which endogenously expresses DRD2) and

132 To search for Wnt genes involved in human teratocarcinomas, with a possible role in human embryoge