ライフサイエンスコーパス: teratogen

1 stasis, whereas excess RA is well known as a teratogen.

2 transition metal cadmium is an environmental teratogen.

3 require treatment with isotretinoin, a known teratogen.

4 Marginal biotin deficiency may be a human teratogen.

5 n the early 1960s after it was found to be a teratogen.

6 result from exposure to this important human teratogen.

7 belief that cocaine is a uniquely dangerous teratogen.

8 odium valproate and carbamazepine, are human teratogens.

9 oxification of environmental carcinogens and teratogens.

10 "proximate zone" of most likely exposure to teratogens.

11 Moreover, astrogliosis may be common to both teratogens.

12 tiologies include the local formation of the teratogen acetaldehyde or oxygen radicals by fetal ethan

13 s well as the causal involvement of specific teratogens acting at the earliest stages of neurulation.

14 ilbestrol (DES), a known human developmental teratogen and carcinogen.

15 lysis indicated that the interaction between teratogen and genotype was highly significant (P < or =

16 Although hyperthermia is a recognized animal teratogen and maternal fever has been associated with bi

17 d suggest apoptosis as a potential target of teratogens and genetic defects that are associated with

18 ren (5000+) worldwide exposed to this potent teratogen, and the many informative cases in which the e

19 New uses for old teratogens as well as novel chemical modulators of devel

20 sy and bipolar disorder and is also a potent teratogen, but its mechanisms of action in any of these

21 een studied for more than 30 years as potent teratogens capable of inducing cyclopia and other birth

22 RA is also a potent teratogen, causing multi-organ birth defects in humans.

23 Teratogens could disrupt the two cellular processes to a

24 Here we show that the plant-derived teratogen cyclopamine, which inhibits the Hh response, i

25 xamine craniofacial defects by a known human teratogen, cyclopamine.

26 served when cocultures were treated with the teratogen cyclophosphamide.

27 These teratogens did not prevent the sterol modification of Sh

28 Although alcohol is a recognized teratogen, evidence is limited on alcohol intake and ora

29 ant exposure were compared with those of non-teratogen-exposed controls.

30 Results showed that teratogen exposure was followed by decreased levels of R

31 into the approximate timing of the causative teratogen exposure.

32 screening platform to mitigate the risks of teratogen exposures in human.

33 apeutic interventions to mitigate effects of teratogen exposures.

34 We propose that increased deposition of teratogens/fetotoxicants to the embryonic compartment is

35 Maternal diabetes, genetic factors and some teratogens have been shown to be associated with its pat

36 Ethanol acts as a teratogen in developing fetuses causing abnormalities of

37 mentally ubiquitous contaminant, is a potent teratogen in mice.

38 only TCAA appeared to be a specific cardiac teratogen in the fetus when imbibed by the maternal rat.

39 zopanib, vandetanib, and everolimus are also teratogens in these models.

40 The fetal brain is sensitive to a variety of teratogens, including ethanol.

41 f teratogens to achieve this; testing single teratogens independently and not examining combinatorial

42 ome-wide search for susceptibility genes for teratogen-induced clefting in the AXB and BXA set of rec

43 an harm neurons subjected to excitotoxic and teratogen-induced injury.

44 omal regions for both forms of clefting when teratogen-induced.

45 We conclude that teratogen induction of p53-dependent apoptosis in the de

46 h both multiple genetic loci and exposure to teratogens influencing susceptibility.

47 gesting that the mechanism of action of this teratogen involves a pathway(s) requiring Paraxis activi

48 Isotretinoin, a known teratogen, is strictly regulated through the iPLEDGE pro

49 We investigated mechanisms of teratogen-mediated blockade of maternofetal transport by

50 xification of and protection from cadmium, a teratogen, mutagen and potentially lethal heavy metal.

51 posed rat embryos to valproic acid, a second teratogen newly linked to autism.

52 basis underlying HPE is not known, although teratogens, non-random chromosomal anomalies and familia

53 e analysed the effects of several classes of teratogens on cartilage formation using 200 independent

54 Retinoic acid (RA), a potent teratogen, produces a characteristic set of embryonic ca

55 In addition, teratogens such as jervine, which inhibit the response o

56 Despite its history as a human teratogen, thalidomide is emerging as a treatment for ca

57 myeloma and inflammatory diseases, is also a teratogen that causes birth defects, such as limb trunca

58 Alcohol is a teratogen that induces a variety of abnormalities includ

59 , an effective anti-acne therapy, is a known teratogen that is strictly regulated through the iPLEDGE

60 um could be a target of genetic mutations or teratogens that cause human conotruncal heart defects.

61 ryonic exposure to ethanol or retinoic acid, teratogens that cause increased cell death.

62 nd epilepsy but it requires a combination of teratogens to achieve this; testing single teratogens in

63 s as epigenetic intermediaries, which permit teratogens to shape complex, divergent developmental pro

64 gate the mechanism of action of a well-known teratogen, valproic acid (VPA).

65 A during pregnancy also use alcohol, a known teratogen, we examined whether local brain volumes diffe

66 embryos treated with valproic acid, a known teratogen which affects somite segmentation, showed pert

67 genetic or genomic variation to exposure to teratogens, which elicit diverse cell and molecular resp

68 DM (classes A1 and A2) is not an established teratogen yet.