ライフサイエンスコーパス: terminal

1 corticothalamic and inhibitory tectothalamic terminals.

2 es of action other than the primary afferent terminals.

3 or capsaicin-induced ablation of nociceptive terminals.

4 es large and rapid acid loads in presynaptic terminals.

5 g in axons and APP processing at presynaptic terminals.

6 t the evolutionarily conserved human CDC73 N-terminal 111 residues form a globularly folded domain (h

7 nal intermembrane space (IMS) domain and a C-terminal 16-stranded beta-barrel domain.

8 es, while the median (2n = 24) presents four terminal 35S sites and three interstitial 5S sites.

9 The ancestral karyotype (2n = 16) has two terminal 35S sites and two interstitial 5S sites, while

10 acid substitution mutations within a PMS2 C-terminal (721)QRLIAP motif attenuate or abolish human Mu

11 -acetyltransferase D (NatD) mediates N-alpha-terminal acetylation (Nt-acetylation) of histone H4 know

12 p53 residence times on chromatin requires C-terminal acetylation-a classical mark for transcriptiona

13 s recently identified as an unconventional N-terminal acetyltransferase (NAT) because it localizes to

14 Lysine 1016 and Phenylalanine1037 with the N-terminal acidic domain of the telomere shelterin protein

15 he presence of Ng13-49 by showing that the N-terminal acidic region of Ng peptide pries open the beta

16 nt ubiquitination and Rqc2p-mediated Carboxy-terminal Alanine and Threonine (CAT) tail elongation-can

17 I) ligands catalyze the cycloaddition of two terminal alkynes and one cyanamide.

18 certain deoxygenated derivatives with either terminal alkynes or borylated alkenes.

19 The addition of terminal alkynes to racemic beta-stereogenic alpha-keto

20 talyzed intermolecular aminosulfonylation of terminal alkynes with sodium sulfinates and TMSN3 is rep

21 respectively, which differ solely in their N-terminal amino acid sequences.

22 ng site residue Y745 and, essentially, the N-terminal amino acids 1-800.

23 tive region(s) of Ov-GRN-1, four truncated N-terminal analogues were synthesized and characterized st

24 made as precursors with positively charged N-terminal anchors, whose cleavage via the prepilin peptid

25 The N-terminal and C-terminal domains of CA (NTD and CTD, resp

26 Effects of N-terminal and C-terminal STIM1 antibodies on TRPC1-based

27 antioselective addition of N-heteroarenes to terminal and internal 1,3-dienes is reported.

28 or Toll-like receptor 4 (TLR4) through its N terminal and modulates STAT3 and TBK1 signaling, trigger

29 an unexpected allosteric site between the C-terminal and the N-terminal helicase cassettes, while 12

30 not disrupt the morphogenesis of presynaptic terminals and dendritic spines, suggesting that glutamat

31 Simulations show frequent exchanges between terminal aquo groups and adsorbed water in locations and

32 The tecto-IOC terminals are delicate and divergent, unlike the promine

33 nd female mice, we show that pulvinocortical terminals are densely distributed in the extrastriate co

34 An Ala mutation of the distal C-terminal Arg-354 or Ser-357, which forms a consensus pho

35 Binding of the intrinsically disordered C-terminal arm of CcdA to the toxin CcdB prevents CcdB fro

36 ed' together is stabilized via a conserved C-terminal arm, which may interact with the portal protein

37 We identify a distinct C-terminal autoinhibitory four-residue sequence in CNAbeta

38 ty troponin T, creatine kinase, myoglobin, N-terminal B-type natriuretic peptide, C-reactive protein,

39 ry glycans could be obtained by removal of a terminal beta-GlcNAc moiety by treatment with beta-N-ace

40 ontracts, resulting in a shortening of the C-terminal beta-strand.

41 ecombinant alpha-syn protein containing an N-terminal bicysteine tag (C2-alpha-syn).

42 nscriptional repressors via recruitment of C-terminal Binding Proteins.

43 tative scaffold interactions involving the N-terminal BRCT domains 1 to 4 of Brc1 have remained obscu

44 Finally, we observed that the N-terminal, but not the C-terminal, moiety of MF6p/HDMs ha

45 factor neuronal pentraxin 1 from presynaptic terminals by signaling through presynaptic protein tyros

46 le 12 binds an RNA-binding site inside the N-terminal cassette.

47 BoNTs are dichain toxins, comprising an N-terminal catalytic domain (LC) disulfide bond linked to

48 revious structural studies showed that the C-terminal catalytic domain of human A3B has a tightly clo

49 Overexcitation of the terminal causes Ca(2+) accumulation and swelling that ca

50 e with beta-arrestins for interaction with C-terminal CB1R domains that could affect agonist-driven,

51 correlated to the br-CF3's proximity to the terminal CF3.

52 Moreover, two C-terminal charges impact CRY2 homo-oligomerization, with

53 By engineering C-terminal charges, we develop CRY2high and CRY2low with e

54 F2, whereas IGF1 displayed homogeneous amino-terminal cleavage with complete removal of the bombyxin

55 footprint extends 13 nucleotides into the N-terminal coding region and, when a mRNA structure overla

56 eration of anaphylatoxins (C3a, C5a) and the terminal complement complex (TCC) that together contribu

57 t activation independent of formation of the terminal complement complex and provide in vivo evidence

58 Formation of terminal complement complex on other complement-activati

59 PV-IR synapses from putative thalamocortical terminals comprised the remaining approximately 40% of P

60 disordered C-terminal linker (CTL), and a C-terminal conserved peptide (CTC).

61 sequence of the phosphorylated CTD via its N-terminal CTD-interacting domain.

62 otropes express a TET1 isoform lacking the N-terminal CXXC-domain, which represses Lhb gene expressio

63 also found that, after addition of a single-terminal Cys residue, a CdtB homologue from cytolethal d

64 In viruses with the N-terminal Cys residues mutated, TF is much less efficient

65 s (classical, alternative, and lectin) and a terminal cytolytic pathway common to all.

66 formational change unveils a region of the N-terminal cytosolic tail targeted by the Art1 alpha-arres

67 The design of the peptides is based on the C-terminal D4 domain of the Escherichia coli polysaccharid

68 Lon recognizes HspQ via a C-terminal degron, whose precise presentation, in synergy

69 critical determinant, Ser5 mutants bearing C-terminal deletions were created.

70 Terminal deoxynucleotidyl transferase dUTP nick end labe

71 ining of occludin, Ki-67, NF-kappaB-p65, and terminal deoxynucleotidyl transferase-mediated dUTP nick

72 tosis of LX-2 cells, as was confirmed by the terminal deoxynucleotidyl transferase-mediated dUTP-biot

73 bi-lobal architecture, with the catalytic N-terminal DHH domain linked to the substrate binding C-te

74 DHH domain linked to the substrate binding C-terminal DHHA1 domain via an extended linker.

75 , it induced expression of a large number of terminal differentiation genes.

76 of Corti and the vestibular organ, impaired terminal differentiation manifests as immature stereocil

77 genome become open for transcription during terminal differentiation, blocking the action of a promi

78 nodules in which bacterial symbionts undergo terminal differentiation.

79 nslational modifications on the RNA pol II C-terminal domain (CTD) and the chromatin template.

80 es the catalytic core domain (CCD) and the C-terminal domain (CTD) of the integrase.

81 (CDK9) recruitment and phospho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II formation

82 ere, we investigate the impact of the PHF1 N-terminal domain (NTD) on the Tudor domain interaction wi

83 Here, we show that Cet1's N-terminal domain (NTD) promotes the recruitment of FACT (

84 , electron density was missing for the p59 N-terminal domain and for the linker connecting it to the

85 apZ at 3.40 A and 3.25 A, and its isolated C-terminal domain at 1.17 A resolution.

86 In addition, the GSDMB N-terminal domain binds liposomes containing sulfatide.

87 the absence of coiled-coil formation, the C-terminal domain bound liposomes and ProP concentrated at

88 lipoxygenases, the topologically conserved C-terminal domain catalyzes the oxidation of polyunsaturat

89 Overexpression of NRP2 or its N-terminal domain enhances VSV-LUJV infection, and cells l

90 ta1-6A2V, which supports a role of Abeta's N-terminal domain in amyloid fibril formation.

91 on the face of the beta-helix whereas the C-terminal domain is likely involved in carbohydrates bind

92 The FliG amino-terminal domain is organized in a regular array with dim

93 ssed by CO2 in a manner dependent on a key C-terminal domain located in its transactivation domain.

94 Here, we report that the hydrophilic N-terminal domain of Brassica napus DGAT1 (BnaDGAT11-113)

95 nteracts with a novel binding motif in the N-terminal domain of CaV1 LTCC alpha1 subunits that is not

96 endent conformational rearrangement of the C-terminal domain of heme binding protein (PhuS) is requir

97 prevents the specific interaction with the N-terminal domain of Hsp90 required for catalysis.

98 suggested that POA binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) and inhib

99 nding with TATA-box DNA, and also with the N-terminal domain of TAF1 previously implicated in TATA-bo

100 e variants identified in the intracellular C-terminal domain of the GluN2B NMDAR subunit.

101 The C-terminal domain of the human Ino80 subunit (Ino80CTD) bi

102 and a higher-order form that adopts carboxyl-terminal domain rearrangements.

103 The amino-terminal domain with a fold distinct among known TRP str

104 ing isoform (LIG3beta) that differs in the C-terminal domain.

105 portant differences in how the Rb and p107 C-terminal domains (CTDs) associate with the coiled-coil a

106 The N-terminal and C-terminal domains of CA (NTD and CTD, respectively) engag

107 ere we solve the crystal structures of the N-terminal domains of PHF1 and MTF2 with bound CpG-contain

108 The terminal domains of suprabasal keratins of the skin epit

109 We find that both the N- and C-terminal domains of TTP are involved in an interaction w

110 The C-terminal DSP domain induced phosphorylation of occludin

111 g differentiation resulted in acquisition of terminal effector cell characteristics, whereas enhancem

112 slational suppression was more pronounced in terminal effector cells than in memory precursor cells a

113 teps controlling postinfection CD8(+) T cell terminal effector versus memory differentiation are inco

114 ormate and facilitate the use of oxygen as a terminal electron acceptor, respectively.

115 activity of cytochrome c oxidase (COX), the terminal electron-accepting complex of the mitochondrial

116 tail that is rich in basic residues at the C-terminal end is responsible for the interaction with RNA

117 C database, confirms that mutations in the N-terminal end of the kinase domain are more disruptive of

118 own for both species that mutations at the C-terminal end of this epitope dramatically improve presen

119 d hydrophobic and polar amino acids at the C-terminal end.

120 enomic characteristics of the regions at the terminal ends of two frequent types of large structural

121 where it truncates core histones at their N-terminal ends.

122 r confirm this function of chloroplasts, the terminal enzyme for melatonin synthesis, N-acetylseroton

123 H from the culture medium completely blocked terminal erythroid differentiation and enucleation.

124 er time with mortality acting as a dependent terminal event.

125 Bacteria encoding L27 with this N-terminal extension also encode a sequence-specific cyste

126 lack TMBS2 and half of ABS1, and present a C-terminal extension containing a proline-rich domain and

127 them to open the F pocket and expose their C-terminal extension into the solvent.

128 The C-terminal extension of capsid protein VP3 folds into a gl

129 Finally, we find that deleting the C-terminal extension of Lmod1 and Lmod2 results in an appr

130 This binding was not affected by cry1's C-terminal extension, which is important for signal transd

131 F loop of VP2, the GH loop of VP3, and the N-terminal extensions of VP1 and VP2, which, in retrospect

132 ation sites to the otherwise divergent amino-terminal extensions on these pollen sPPases.

133 with the crystal structure of the isolated N-terminal extracellular domain of the GLP-1R in complex w

134 ts the normal age-dependent "pruning" of all terminal fields, which could lead to alterations in sens

135 f ubiquitin, two interhelical loops of the C-terminal four-helix bundle appear to penetrate the membr

136 We show that an N-terminal fragment comprising the catalytic domain can in

137 n2 TM2 leads to the appearance of a carboxyl-terminal fragment consistent with intramembrane proteoly

138 d for a mixture of Abeta1-28WT and a short N-terminal fragment, Abeta1-6A2V, which supports a role of

139 n can interact both with itself and with a C-terminal fragment.

140 studies have shown that the aggregation of N-terminal fragments (encoded by HTT exon 1) underlies the

141 ously characterized viruses expressing amino-terminal fusions, this virus expresses more VP26 fusion

142 nts, including high mannose, sialylated, and terminal galactosylated species were studied in detail.

143 g properties of 40 CBMs, in fusion with an N-terminal GFP domain, revealed that type A CBMs possess t

144 sting a similar expansion of cells that lack terminal glial differentiation.

145 can-binding proteins uncovered that not only terminal glycoepitopes but also complex architectures of

146 o cleave the N-terminal prodomain from the C-terminal growth factor (GF) domain in each monomer, pro-

147 sphorylation-dependent (40E8 and p396) and C-terminal half (4E4) tau antibodies also reduced tau upta

148 we determined the crystal structure of the N-terminal half of a conserved tegument protein, UL37, fro

149 tic domain (LC) disulfide bond linked to a C-terminal heavy chain (HC) which includes a translocation

150 steric site between the C-terminal and the N-terminal helicase cassettes, while 12 binds an RNA-bindi

151 ich the small molecule stabilizes a mobile C-terminal helix inside a hydrophobic crevice of NCS-1 to

152 permits positively charged residues in the C-terminal helix to engage in DNA binding, triggering a ma

153 The C-terminal homology domain (CHD) of Af4 was sufficient to

154 Using the endocytic protein epsin1 N-terminal homology domain (ENTH), previously thought to d

155 e demonstrate an essential role of TH during terminal human erythroid cell differentiation; specific

156 In contrast, the N-terminal hydrophobic core showed extremely slow solvent

157 n associated with DSD activity and a novel C-terminal hydroxyphenylpyruvate dioxygenase-like domain.

158 Optogenetic inhibition of PBel(CGRP) terminals identified a network of forebrain sites under

159 ere we report the crystal structure of the N-terminal IMS domain of Toc75 from Arabidopsis thaliana,

160 The C-terminal in-frame green fluorescent protein fusion may s

161 t, unlike the prominent convergent tecto-ION terminals in Neognathae.

162 both GABA and GABA-A receptors to their axon terminals in the EB, and optogenetic stimulation coupled

163 l activity when ATP consumption within nerve terminals increases drastically.

164 erminal "thumb" and a disulfide-stabilized C-terminal "index finger," yet how these binding events tr

165 sonance spectroscopy demonstrated that the N-terminal inhibitory domain (NID) is intrinsically disord

166 o have a beta-barrel fold consisting of an N-terminal intermembrane space (IMS) domain and a C-termin

167 ous neurological diseases, its role at nerve terminals is poorly understood.

168 e ER-Golgi-cycling FKBP proteins contain a C-terminal KDEL-like sequence, bind ST-FRB in the Golgi, a

169 inflammatory skin disease, is driven by both terminal keratinocyte differentiation defects and strong

170 re TBI elicits neuroinflammation and c-Jun-N-terminal kinase (JNK) activation, which is associated wi

171 show that ATZ induces activation of c-Jun N-terminal kinase (JNK) and c-Jun and that genetic ablatio

172 Moreover, c-Jun N-terminal kinase (JNK) has been implicated in regulation

173 Because islet amyloid increases c-Jun N-terminal kinase (JNK) pathway activation, we investigate

174 c-Jun N-terminal kinase (JNK) plays a vital role in malignant tr

175 tor of both IkappaB kinase (IKK) and c-Jun N-terminal kinase (JNK), and an important mediator of auto

176 sor function for KIND1, and identify c-Jun N-terminal kinase and NF-kappaB as potential therapeutic t

177 optosis and recently a specific JNK (c-Jun N-terminal kinase)-dependent S574 phosphorylated form (p-F

178 Abnormal accumulation of Abeta at nerve terminals leads to synaptic pathology and ultimately to

179 GTPase domain, an intrinsically disordered C-terminal linker (CTL), and a C-terminal conserved peptid

180 rectly destabilize the complex through the N-terminal linker.

181 nt on both the presence of a 22-amino-acid N-terminal 'loop' region and its catalytic activity.

182 on of K29-linked ubiquitin chains with two N-terminal loops of Ufd2p.

183 reactivity against recombinantly expressed N-terminal LRP2 fragments on Western blots and immunopreci

184 ta contains a specific NLS sequence in the N-terminal lyase domain that promotes transport of the pro

185 An APP mutant lacking all C-terminal lysines underwent the most pronounced increase

186 Here, we show that substitution of APP C-terminal lysines with arginine disrupts APP ubiquitinati

187 n a primary binding site and the nonreducing terminal mannose residue occupying an adjacent secondary

188 on of cell migration as a feature of NK cell terminal maturation in this system.

189 rrier is established through the coordinated terminal maturation of the retinal pigment epithelium (R

190 modes of migration that are associated with terminal maturation.

191 and that limiting Ca(2+) accumulation in the terminal may protect against hearing loss.

192 hyltransferase activity of MEPCE through a C-terminal MEPCE interaction domain (MID).

193 Truncations, N-terminal methionine excision, signal peptide removal, an

194 Furthermore, it is shown that this type of C-terminal modification may be combined with a second peri

195 otein and the peptide corresponding to the N-terminal moiety of MF6p/FhHDM-1 interact in vitro with c

196 observed that the N-terminal, but not the C-terminal, moiety of MF6p/HDMs has a predicted structural

197 d that the use of allosterically regulated C-terminal motifs could be a common mechanism for PilZ ada

198 vised road map emphazises close parallels of terminal mTEC development with that of skin, undergoing

199 The first complex featuring an unsupported, terminal multiple bond between a Ce(IV) ion and a ligand

200 hydrogen atom abstraction and synthesis of a terminal nitride from coordinated ammonia, a key step in

201 The molecular basis of how the N-terminal non-catalytic CD1 regulates the catalytic activ

202 N-terminal nuclear localization signal and C-terminal nuclear export signal (NES).

203 istic activities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nucl

204 isoforms were full length, containing the N-terminal nuclear localization signal.

205 e between the transmembrane domain and the C-terminal nucleotide binding domain.

206 h amphipathic peptide sequence attached to N-terminal of bZIP53 leucine zipper.

207 The N-terminal of MyRF, which contains a proline-rich region a

208 alpha-synuclein is found at the presynaptic terminals of dementia with Lewy bodies cases mainly in t

209 e performed live Ca(2+) imaging in the nerve terminals of gonadotropin-releasing hormone neurons.

210 umulation of intermediate filaments in nerve terminals of the neuromuscular synapse and improves the

211 t abundant being transcripts containing a 5' terminal oligopyrimidine (5' TOP) motif.

212 erse late transition metal catalysts convert terminal or internal alkynes into transient allylmetal s

213 DP4+ methodology in the stereoassignment of terminal or spiroepoxides bearing a wide variety of mole

214 n partners interact via association of the C-terminal or transmembrane segments, with consequences fo

215 Mutation of the start codon of two C-terminal ORFs in an infectious clone reduced virus yield

216 a periplasmic formate dehydrogenase and two terminal oxidases, which serve to metabolize formate and

217 The C-terminal pair of BRCT domains in Brc1 were previously sh

218 alpha-synuclein levels sufficient to induce terminal pathology without significant loss of nigral ne

219 CRIP1a, but that a phosphorylated central C-terminal peptide competed for association with beta-arre

220 d replacements on lipid association of the C-terminal peptide fully recapitulated their effects on th

221 nce, the protein was identified as a carboxy-terminal peptide of the acute phase protein serum amyloi

222 in 1, and phosphorylated central or distal C-terminal peptides competed for association with beta-arr

223 plexes demonstrated that central or distal C-terminal peptides competed for the CB1R association with

224 ternal metal nodes of MOF nanoparticles with terminal phosphate-modified oligonucleotides.

225 We explored the functionality of two terminal PKS modules that produce the 16-membered tylosi

226 of the antiviral drug, amantadine, at the N-terminal pore at low pH did not convert all histidines t

227 e change in 6-minute walk distance, plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) leve

228 high-dose spironolactone and usual care on N-terminal pro-B-type natriuretic peptide (NT-proBNP) leve

229 ailure score (48 versus 40), higher median N-terminal pro-B-type natriuretic peptide concentration (4

230 congestion, worse quality of life, higher N-terminal pro-B-type natriuretic peptide levels, and a po

231 mL [517-768 mL]; P<0.0001), despite lower N-terminal pro-B-type natriuretic peptide levels.

232 serial measurement of soluble ST2 and amino-terminal pro-B-type natriuretic peptide to clinical para

233 n class III/IV, RVESRI, and log NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) were retained (

234 entation index, (4) circulating NT-proBNP (N-terminal pro-B-type natriuretic peptide), TNF-alpha, IL-

235 fter processing in the Golgi to cleave the N-terminal prodomain from the C-terminal growth factor (GF

236 bridges with Cys-158 of the very flexible N-terminal propeptide being covalently linked to Cys-319 a

237 N-terminal propeptide of type I procollagen (PINP) and C-t

238 phosphorylation of residues in alpha1C and C-terminal proteolytic cleavage of the alpha1C subunit.

239 ines cationic, unambiguously demonstrating C-terminal protonation of H37 in the mutant.

240 the bacterial chemotaxis protein CheY, the N-terminal receiver domain of the nitrogen regulation prot

241 ing question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA-SP1), whic

242 non-synonymous substitution (A120G) in the N-terminal region of eIF2Bbeta was responsible for the TuM

243 sugar modifications and revealed that the C-terminal region of FUS is sufficient to retain ASOs in c

244 noprecipitated the recombinantly expressed N-terminal region of LRP2.

245 TFAM tethers the N-terminal region of mtRNAP to recruit the polymerase to t

246 The interaction occurred through the C-terminal region of RING1B (C-RING1B), with an affinity i

247 d versions of SS4 and a fusion between the N-terminal region of SS4 and GS in the Arabidopsis ss4 mut

248 caused by a polyglutamine expansion in the N-terminal region of the huntingtin protein (N17).

249 O homooligomerization, mediated by the amino-terminal region of the protein, and carboxyl-terminal ta

250 mediated by the coiled-coil domain at the N-terminal region of the protein.

251 An unstructured N-terminal region of Tim10 is necessary and sufficient to

252 actions of the central part of Tm with the C-terminal region of TnI.

253 cyclin F-specific amino acid motif in the C-terminal region of Vif indicated rescue of the protein f

254 n TRP structures, together with the carboxyl-terminal region, forms a large two-layered cytosolic rin

255 ith deletion of residues 338 to 347 in the C-terminal region, has been an enigma, because the basis f

256 m the presence of an acidic residue at its N-terminal region.

257 estigated the specific roles of the N- and C-terminal regions of SS4 by expressing truncated versions

258 e transcriptional activity of the viral long terminal repeat (LTR) from Vpr-deficient proviruses was

259 recombination with specific classes of long terminal repeat (LTR) retrotransposons and organize into

260 ter phenotypically resembles endogenous long terminal repeat (LTR) sequences, pointing to a select ro

261 ons in the regulatory elements in their long terminal repeats and differed in a helical segment of en

262 Here, we show that the regulatory N-terminal residues and the EH domain keep the EHD2 dimer

263 on the formation of hydrogen bonds between C-terminal residues of lentil peptides and residues of the

264 ec72, even though it lacks the TPR-binding C-terminal residues of Ssa1.

265 expressing DAT selectively in DA neurons and terminals, resulting in the rescue of aberrant striatal

266 the effect of three enhanced strategies for terminal room disinfection (disinfection of a room betwe

267 e versa during development, which affect the terminal seam cell number in opposing directions.

268 by the SCI's B and C domains encircles the C-terminal segment of the IR alpha-subunit.

269 f the permeation of the lethal factor (LF) N-terminal segment through the anthrax channel.

270 we ectopically expressed C. elegans CHE-1, a terminal selector of ASE sensory neuron identity.

271 The conserved COE-type terminal selector UNC-3 not only controls the expression

272 d by its collaboration with non-sex-specific terminal selector-type transcription factors, whereas th

273 Manipulation of the N-terminal sequence affected the amount of Polbeta in the

274 cifically recognize a four-amino acid CAAX C-terminal sequence within their substrates.

275 its relative molecular mass of 7287 and NH2-terminal sequence, the protein was identified as a carbo

276 F region; however, a specific role for the C-terminal set of five ZFs remains to be elucidated.

277 uptake of tau species, whereas the distal C-terminal-specific antibody (Tau46) had little effect.

278 Effects of N-terminal and C-terminal STIM1 antibodies on TRPC1-based SOCs and STIM1

279 ngs demonstrate that the occurrence of amino-terminal structural homogeneity may be associated with t

280 rase component, which contains a conserved C-terminal structural loop, preferentially binds to and fi

281 in is a fusion of two distinct modules: an N-terminal sugar phosphate isomerase-like domain associate

282 This C-terminal tail displays the binding site for partner prot

283 terminal region of the protein, and carboxyl-terminal tail identity both contribute to MLO activity d

284 by hyperphosphorylation of the inhibitory C-terminal tail of Lck.

285 ylation of several Ser/Thr residues in the N-terminal tail.

286 d to extend the Ser65 loop and shorten the C-terminal tail.

287 r phosphorylation, often at the receptor's C-terminal tail.

288 that contained only one tyrosine in their C-terminal tail.

289 tau uptake in an epitope-dependent manner: N-terminal (Tau13) and middomain (6C5 and HT7) antibodies

290 suppression of bone turnover (assessed by C-terminal telopeptide levels).

291 as shown a maximum rectification of 10.9% at terminals' temperatures of 375 and 530 K.

292 ASK1 kinase domain in conjunction with its N-terminal thioredoxin-binding domain, along with a centra

293 with high affinity through a palmitoylated N-terminal "thumb" and a disulfide-stabilized C-terminal "

294 expressing the target protein with SpyTag C-terminal to the SrtA recognition motif, it can be covale

295 We found different levels of C-terminal truncation, soluble protein aggregates, and gly

296 t to be transported to axons and presynaptic terminals where they signal via ErbB3/4 receptors in par

297 xocytosis from a subset of cortical synaptic terminals within the EC and in this way, constrain non-a

298 une evasion protein, E3, which contains an N-terminal Z-nucleic acid binding (Zalpha) domain that is

299 d for its conserved methylated DNA binding N-terminal ZF region; however, a specific role for the C-t

300 and a polarity reversal at the center of the terminal zone.