ライフサイエンスコーパス: terminal domain

1 ite for full activity and is mediated by a C-terminal domain.

2 epression of Trio GEF activity by the Trio N-terminal domain.

3 s tightly regulated in cis by the globular C-terminal domain.

4 ing isoform (LIG3beta) that differs in the C-terminal domain.

5 re of the four-helix bundle that forms the C-terminal domain.

6 this pore opens independent of its unique C-terminal domain.

7 plex, which is also controlled by MARCH5's C-terminal domain.

8 he various heptad repeat motifs within the C-terminal domain.

9 h phosphorylation of the RNA polymerase II C-terminal domain.

10 de in the catalytic barrel rather than the N-terminal domain.

11 conserved residue located within the PKD1 N-terminal domain.

12 pases, cleave GSDMB at 88DNVD91 within the N-terminal domain.

13 s makes extensive contacts with the folded N-terminal domain.

14 nalysis to investigate the function of the C-terminal domain.

15 anslate ADP binding into a movement of the N-terminal domain.

16 than the anticipated Rossmann fold of the N-terminal domain.

17 s translocation of the carotenoid into the N-terminal domain.

18 istent with a more folded and less dynamic C-terminal domain.

19 ved oligomerization interface in the mVP40 N-terminal domain.

20 N-terminal domain, a middle domain, and a C-terminal domain.

21 rstood region of the polymerase called the N-terminal domain.

22 rents when expressed in the absence of the C-terminal domain.

23 orthologues share an extended, cytoplasmic C-terminal domain.

24 rough adjacent conserved interfaces in its C-terminal domain.

25 l imply asymmetric sequential binding of the terminal domains.

26 the binding affinities of conserved N- and C-terminal domains.

27 tinct coiled-coil domains: the central and C-terminal domains.

28 e a tunnel formed by the two RecA-like and C-terminal domains.

29 RNA binding by large rearrangements of the C-terminal domains.

30 ins to the ATPase, Rubisco recognition and C-terminal domains.

31 it bound strongly to monomeric CRP via its C-terminal domains.

32 ve established that DnaB is composed of an N-terminal domain, a middle domain, and a C-terminal domai

33 Ligands binding to the N-terminal domain abolish the spontaneous ionic currents a

34 11 Here, we identified a region within the C-terminal domain (amino acids 852-876) that is necessary

35 DA16 structure revealed a small 80-residue N-terminal domain and a C-terminal 8-bladed beta-propeller

36 DP-bound state, showing the characteristic N-terminal domain and a central G domain that are common t

37 by the protein's intrinsically disordered C-terminal domain and an incipient amphipathic alpha-helix

38 two decavanadate-binding sites, one in the C-terminal domain and another in the intersubunit MHR inte

39 mplex can efficiently interact with clathrin terminal domain and ERK2 MAPK in vitro.

40 , electron density was missing for the p59 N-terminal domain and for the linker connecting it to the

41 e presence of an L138P mutation in the VP1 N-terminal domain and identifying 52 additional mutations

42 keletal muscle and has a large cytoplasmic N-terminal domain and smaller C-terminal pore-forming doma

43 eins Prp38, Snu23 and Spp381 bind the Prp8 N-terminal domain and stabilize U6 ACAGAGA stem-pre-mRNA a

44 een TMR (donor) bound to a cysteine in the C-terminal domain and the carotenoid (acceptor) increased

45 ctivity that reside between the GluN2C amino terminal domain and the GluN2C agonist binding domain, s

46 The peptide is clasped between the N-terminal domain and the transmembrane core of the recept

47 rmational changes are detected both at the N-terminal domain and within the substrate portal nearly 3

48 hat lipid binds between the N-terminal and C-terminal domains and that separation of the two domains,

49 way originating from the nucleation of the N-terminal domain, and that this pathway is the least like

50 e associated Zwilch subunit bind Spindly's C-terminal domain, and we identify a specific Zwilch mutan

51 lar membrane surface and the intracellular C-terminal domain are visible in the structure.

52 d by proprotein convertases to release the C-terminal domain as an active ligand dimer.

53 potential oligomerization interface in the C-terminal domain as well as a conserved oligomerization i

54 apZ at 3.40 A and 3.25 A, and its isolated C-terminal domain at 1.17 A resolution.

55 The crystal structure of the N-terminal domain at 1.7 A resolution comprising residues

56 The amino-terminal domain (ATD) of AMPA receptors (AMPARs) account

57 e absence of Ro, the GluN2A and GluN2B amino-terminal domains (ATDs) adopt "closed" and "open" clefts

58 homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling assemb

59 steric Ras independently of the well-known N-terminal domain autoinhibition.

60 RapZ possesses a kinase fold, whereas the C-terminal domain bears closest homology to a subdomain of

61 Bromodomain and extra-terminal domain (BET) chromatin adaptors serve as immuno

62 Bromodomain and extra-terminal domain (BET) inhibitors are widely used both as

63 viously identified the bromodomain and extra-terminal domain (BET) protein BRD4 as an epigenetic regu

64 These molecules target Bromodomain and Extra Terminal domain (BET) proteins, which are epigenetic rea

65 e show that both full-length GSDMB and the N-terminal domain bind to nitrocellulose membranes immobil

66 1A C-terminal domain, but not the GST-mu1A N-terminal domain, bind to L-selectin tail peptide, and th

67 In addition, the GSDMB N-terminal domain binds liposomes containing sulfatide.

68 The cleaved N-terminal domain binds phosphoinositides and cardiolipin,

69 mature, cleaved, C-terminal AgRP, not the N-terminal domain, binds heparan sulfate.

70 the absence of coiled-coil formation, the C-terminal domain bound liposomes and ProP concentrated at

71 ore, full-length GST-mu1A and the GST-mu1A C-terminal domain, but not the GST-mu1A N-terminal domain,

72 Moreover, the free C-terminal domain can rapidly decondense ParB networks ind

73 lipoxygenases, the topologically conserved C-terminal domain catalyzes the oxidation of polyunsaturat

74 end domains are likely to form a tetrameric terminal domain complex incorporating a reversibly exten

75 The tetrameric terminal domain complex model may also help to elucidate

76 Bromodomain (BD) and extra-terminal domain containing proteins (BET) are chromatin

77 ression of the multifunctional BRCT (BRCA1 C-terminal) domain-containing PTIP (Pax transactivation do

78 a novel ATPase, Sulfolobus islandicusPilT N-terminal-domain-containing ATPase (SisPINA), encoded by

79 X-ray crystallography and NMR results, the N-terminal domain contains four alpha-helices, 20 to 30 am

80 Deletion of the C-terminal domain converted CsxA into a distributive enzym

81 The function of the XND1 C-terminal domain could be partially replaced by RBR fused

82 re, we characterized a novel cysteine-rich C-terminal domain (CRD), which is present in most class II

83 ugh its interaction with RNA Polymerase II C-terminal domain (CTD) and affecting the expression level

84 HKU1 virus uses its S1 subunit C-terminal domain (CTD) and not the N-terminal domain like

85 nslational modifications on the RNA pol II C-terminal domain (CTD) and the chromatin template.

86 jor matrix-exposed loop of Tim23, with the C-terminal domain (CTD) binding Tim17 as well.

87 ns a repetitive, intrinsically disordered, C-terminal domain (CTD) composed of heptads of the consens

88 nodeficiency virus type 1 (HIV-1) CA carboxy-terminal domain (CTD) is essential for CA-CA interaction

89 The H1 C-terminal domain (CTD) localizes primarily to a single li

90 connecting the N-terminal domain (NTD) and C-terminal domain (CTD) of AhpF suggests that the enzyme a

91 Many of these proteins bind the C-terminal domain (CTD) of FtsZ, which serves as a hub for

92 The C-terminal domain (CTD) of hepadnavirus core protein is in

93 MPORTANCE The phosphorylation state of the C-terminal domain (CTD) of hepatitis B virus (HBV) core or

94 VSV by its polymerase are provided by the C-terminal domain (CTD) of P.

95 ively regulated by ATP, which binds to the C-terminal domain (CTD) of Sirt1.

96 es the catalytic core domain (CCD) and the C-terminal domain (CTD) of the integrase.

97 the post-translational modification of the C-terminal domain (CTD) of the largest subunit of RNA poly

98 The carboxyl-terminal domain (CTD) of the largest subunit of RNA poly

99 The carboxy-terminal domain (CTD) of the RNA polymerase II (Pol II)

100 opo II-targeted drugs is influenced by the C-terminal domain (CTD) of the topo II isoforms and by a c

101 The Ska1 C-terminal domain (CTD) recruits protein phosphatase 1 (PP

102 rylation of the RNA polymerase II (Pol II) C-terminal domain (CTD) regulates transcription of protein

103 The GluN2B cytoplasmic C-terminal domain (CTD) represents an alternative therapeu

104 (CDK9) recruitment and phospho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II formation

105 nt to gene promoters and decreased RNAP II C-terminal domain (CTD) Ser2 phosphorylation during VHSV i

106 Hfq possesses an intrinsically disordered C-terminal domain (CTD) that may tune the function of the

107 RNA polymerase II contains a long C-terminal domain (CTD) that regulates interactions at the

108 ind that Rbfox interacts with LASR via its C-terminal domain (CTD), and this domain is essential for

109 TEFb-associated RNA polymerase II (RNAPII) C-terminal domain (CTD)-Ser7 phosphorylation at the WNT3 g

110 old higher abundance of a novel ('-12-40') C-terminal domain (CTD)-variant in the SCN.

111 ong C-terminal extension, called the carboxy-terminal domain (CTD).

112 portant differences in how the Rb and p107 C-terminal domains (CTDs) associate with the coiled-coil a

113 es, such as the exonuclease/polymerase and C-terminal domains (CTDs) of catalytic subunits bound to i

114 or complex subunit 9 (IntS9) through their C-terminal domains (CTDs).

115 ndent, and phosphomimetic mutations in the C-terminal domain did not result in unmasking of the catal

116 an ADP-driven downward movement of the p97 N-terminal domain dislodges ataxin3 by inducing a steric c

117 obacterial F-ATP synthases deletion of the C-terminal domain enabled ATPase and proton-pumping activi

118 Overexpression of NRP2 or its N-terminal domain enhances VSV-LUJV infection, and cells l

119 -length TDP-43, association between folded N-terminal domains enhances the propensity of the intrinsi

120 catalytic motifs, the isolated TlyA carboxyl-terminal domain exhibits no detectable affinity for SAM.

121 Four cytosolic C-terminal domains form an umbrella-like structure with a

122 y mutants interacted with the SaPIbov1 Stl C-terminal domain, formed DutNM1-Stl heterodimers, and cau

123 d between two IN tetramers, with a pair of C-terminal domains from flanking tetramers completing the

124 d N-terminal ATP PPase domain and a unique C-terminal domain harboring the putative catalytic site.

125 ng (SAXS) data revealed that the protein's C-terminal domain has a PG-binding-competent conformation.

126 N-terminal domain homologs, the helical carotenoid protein

127 As a result of disulfide shuffling in its terminal domains, hPDI exists in two oxidation states wi

128 ta1-6A2V, which supports a role of Abeta's N-terminal domain in amyloid fibril formation.

129 present two crystal structures of the MutY N-terminal domain in complex with either undamaged DNA or

130 e of JBC, Brown and co-workers identify an N-terminal domain in SM that interconverts in a cholestero

131 The roles of phospholipids and the C-terminal domain in subcellular localization of ProP were

132 Mycobacterium-specific, 36-amino acid long C-terminal domain in the nucleotide-binding subunit alpha

133 mate-gamma-semialdehyde dehydrogenase, and C-terminal domains, including an extended interdomain tunn

134 alysis of the structural model of the L142 N-terminal domain indicated significant homology with some

135 n we overexpressed mutants lacking part of N-terminal domains, indicating that the IL1RAPL1 extracell

136 i-PrP antibodies targeting epitopes in the C-terminal domain induce currents, and cause degeneration

137 eurotoxic mutants of PrP, and the isolated N-terminal domain induces currents when expressed in the a

138 targeting SEs with the bromodomain and extra-terminal domain inhibitor JQ1, or knockdown of overlappi

139 hosphatase activities, and both the N- and C-terminal domains interact with substrates to increase th

140 olving a region of the middle domain/carboxy-terminal domain interface previously suggested to be a s

141 d NMR analyses, we confirmed that the L142 N-terminal domain is a sugar acetyltransferase, catalyzing

142 a truncated form lacking the 17- to 20-kDa N-terminal domain is completely inactive under identical c

143 te liposomes, the overall structure of the C-terminal domain is in good agreement with crystallograph

144 on the face of the beta-helix whereas the C-terminal domain is likely involved in carbohydrates bind

145 The FliG amino-terminal domain is organized in a regular array with dim

146 The C-terminal domain is permissive to cytoplasmic shuttling a

147 The C-terminal domain is relatively unstructured in the monome

148 Its N-terminal domain is the active part of the protein, and t

149 the native wild-type protein, whereas the N-terminal domain is unfolded and comprises an ensemble of

150 CL59 binds to the C-terminal domain IV of gH, while CL40 binds to a site occ

151 rring DLX3 mutant that disrupts the carboxyl-terminal domain leading to tricho-dento-osseous syndrome

152 ength IL1RAPL1 and mutants lacking part of C-terminal domains leads to simplified neuronal arborizati

153 ubunit C-terminal domain (CTD) and not the N-terminal domain like other lineage A beta-CoVs to bind t

154 f NTD, and name this truncated variant the C-terminal domain-like carotenoid protein (CCP).

155 ssed by CO2 in a manner dependent on a key C-terminal domain located in its transactivation domain.

156 nstrates that two basic loops in the mVP40 C-terminal domain make important contributions to anionic

157 formation by Bordetella lacking the mature C-terminal domain (MCD), suggesting the direct interaction

158 tics predicts that MOSP consists of N- and C-terminal domains, MOSP(N) and MOSP(C).

159 on gene construction methodology to screen N-terminal domain mutations discovered in tumors that are

160 dition to the stabilization of either Rrn7 N-terminal domain near Pol I wall or the tandem winged hel

161 The structure shows that the NusG N-terminal domain (NGN) binds at the central cleft of RNA

162 icellar structures, where the very soluble N-terminal domain (NT) forms the shell.

163 -methyl-d-aspartate (NMDA) receptor GluN2B N-terminal domain (NTD) aims for the treatment of various

164 A flexible linker connecting the N-terminal domain (NTD) and C-terminal domain (CTD) of Ahp

165 arly define the roles of the HTLV-1 CA amino-terminal domain (NTD) and CA CTD in particle biogenesis,

166 TDP-43's N-terminal domain (NTD) is important for these activities

167 ts of in vitro experiments showed that the N-terminal domain (NTD) is intrinsically disordered and bi

168 Tyr(30), Tyr(64), and Tyr(86) in the N-terminal domain (NTD) of beta-catenin.

169 und to DnaB alters the conformation of the N-terminal domain (NTD) of DnaB to impair the ability of t

170 ere, we investigate the impact of the PHF1 N-terminal domain (NTD) on the Tudor domain interaction wi

171 Here, we show that Cet1's N-terminal domain (NTD) promotes the recruitment of FACT (

172 c conformational equilibrium involving the N-terminal domain (NTD) with implications for the binding

173 ices, we show that the extracellular AMPAR N-terminal domain (NTD), which projects midway into the sy

174 atidylserine binds to an integral-membrane N-terminal domain (NTD); however, how the NTD activates th

175 MAD2-interaction motif (MIM), both N- and C-terminal domains (NTD and CTD) of MAD1 also contribute t

176 Previously, we have shown that the sHSP N-terminal domains (NTDs), which have a high degree of int

177 Original work proposed that the N-terminal domain of AgRP facilitates this interaction.

178 arges of acetylable lysine residues in the N-terminal domain of APE1 are essential for chromatin asso

179 tive charges of the lysine residues in the N-terminal domain of APE1 induces a conformational change;

180 ut is atypical in having a non-homologous, C-terminal domain of approximately 20 kDa and at least one

181 The positively charged C-terminal domain of ArfA anchors in the mRNA entry channe

182 cific interactions between residues in the N-terminal domain of ArfA and RF2 help RF2 to adopt a cata

183 l is proposed illustrating the role of the N-terminal domain of BnaDGAT1 as a positive and negative m

184 Here, we report that the hydrophilic N-terminal domain of Brassica napus DGAT1 (BnaDGAT11-113)

185 use model carrying a mutation in the BRCA1 C-terminal domain of BRCA1.

186 nteracts with a novel binding motif in the N-terminal domain of CaV1 LTCC alpha1 subunits that is not

187 Densin binds to the N-terminal domain of Cav1.2, but not that of Cav1.3, and i

188 ed central domain of CENP-C and the folded N-terminal domain of CENP-N that becomes rigidified 1,000-

189 279/282, 365, 368, and 373 located in the C-terminal domain of connexin43 (Cx43) into glutamic acid

190 teolysis of spheroplasts revealed that the C-terminal domain of CpaB is exposed to the periplasm, sug

191 the C-terminal beta-propeller but not the N-terminal domain of CrODA16 is required for the interacti

192 n binding by CshA, in which the disordered N-terminal domain of CshA acts to "catch" Fn, via formatio

193 This suggests that Ca(2+) affinity of the N-terminal domain of cTnC in isolation is insufficient to

194 ctions that begins with the opening of the N-terminal domain of cTnC, followed by cTnC binding the tr

195 The N-terminal domain of DENV NS5 has guanylyltransferase and

196 e elucidation of the NMR structures of the C-terminal domain of EB1 in the free form and complexed wi

197 duce a conformational rearrangement in the C-terminal domain of ExoU.

198 We show that the rotated C-terminal domain of FIN219 alters ATP binding and the cor

199 Cleavage releases the N-terminal domain of GSDMD, causing it to form cytotoxic p

200 endent conformational rearrangement of the C-terminal domain of heme binding protein (PhuS) is requir

201 ermal calorimetry, which suggests that the C-terminal domain of hISG15 is principally responsible for

202 prevents the specific interaction with the N-terminal domain of Hsp90 required for catalysis.

203 ction to the CARD domains of RIG-I and the N terminal domain of La.

204 on and that CHMP7 can bind directly to the C-terminal domain of LEM2 in vitro.

205 nking was not prevented by deletion of the N-terminal domain of NPC1, which contains the initial bind

206 LUJV GP binds the N-terminal domain of NRP2, while CD63 stimulates pH-activa

207 The C-terminal domain of nsp5 was shown to be required for the

208 rotenoid Proteins [HCPs]), paralogs of the N-terminal domain of OCP, were described.

209 In this process, the N-terminal domain of p30 released from GSDMD acts as an ef

210 Our work reveals a dual role for the C-terminal domain of ParB as both a DNA binding and bridgi

211 polymerase (RNAP), also interacts with the C-terminal domain of PigR, thus anchoring the (MglA-SspA)-

212 tructural model of DnaB complexed with the C-terminal domain of primase, we found that Ile-85 is loca

213 cal techniques, we show that the flexible, N-terminal domain of PrP(C) functions as a powerful toxici

214 is inhibitory effect required the globular C-terminal domain of PrP(C), which has not been previously

215 The crystal structure of the N-terminal domain of pyoS2 (pyoS2(NTD)) bound to FpvAI (Kd

216 we initially present the structure of the N-terminal domain of QseB, the response regulator responsi

217 The structural data confirm that the N-terminal domain of RapZ possesses a kinase fold, whereas

218 The most N-terminal domain of Reck binds to the leucine-rich repeat

219 novel bipartite degradation signal in the N-terminal domain of RGS2.

220 suggested that POA binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) and inhib

221 N-terminal prion-like domain (PLD) to the C-terminal domain of RNA polymerase II.

222 We then map SUMOylation sites to the C-terminal domain of septins belonging to the SEPT6 and SE

223 g to the SEPT6 and SEPT7 groups and to the N-terminal domain of septins from the SEPT3 group.

224 ays and showed that hsp70 binds to the amino-terminal domain of SOD2.

225 and of type I IFN but required a distinct C-terminal domain of STING that activates NF-kappaB.

226 Although the N-terminal domain of SuiB adopts a typical RRE (RiPP recog

227 nding with TATA-box DNA, and also with the N-terminal domain of TAF1 previously implicated in TATA-bo

228 eparately with CTD and the latter with the N-terminal domain of the C-subunit.

229 on within the compound-binding site in the N-terminal domain of the CA protein.

230 A [4Fe4S](2+) cluster in the C-terminal domain of the catalytic subunit of the eukaryot

231 e variants identified in the intracellular C-terminal domain of the GluN2B NMDAR subunit.

232 The C-terminal domain of the human Ino80 subunit (Ino80CTD) bi

233 the iron-sulfur cluster buried inside the C-terminal domain of the large primase subunit (p58C).

234 ains a 197-amino-acid (aa) deletion in the N-terminal domain of the spike (S) protein.

235 cated two regions in the extracellular amino-terminal domain of the subunit: the E loop (a loop of th

236 ested that conformational changes within a C-terminal domain of the toxin might be involved in the ac

237 at MB-10 binds to a specific pocket in the C-terminal domain of Tim44 of the protein-associated motor

238 We found that the C-terminal domain of TPX2 contributes to the localization

239 The C-terminal domain of TPX2 contributes to the localization

240 lar spindle formation in vivo requires the C-terminal domain of TPX2.

241 be partially replaced by RBR fused to the N-terminal domain of XND1.

242 The binding interface is centered on the C-terminal domain of YscU.

243 The N- and C-terminal domains of all gasdermins possess lipid-binding

244 The N-terminal and C-terminal domains of CA (NTD and CTD, respectively) engag

245 ow determined the crystal structure of the C-terminal domains of eIF2D at 1.4-A resolution.

246 mmon docking (CD) domain within the carboxyl-terminal domains of ERK3 and ERK4 and the conserved kina

247 Both N- and C-terminal domains of Gal-9 bound m4-1BB, but with lower a

248 We show that the C-terminal domains of Gea1 and Gea2 toggle roles in the cy

249 ere we solve the crystal structures of the N-terminal domains of PHF1 and MTF2 with bound CpG-contain

250 e association of peptides representing the C-terminal domains of ProP orthologues and variants in vit

251 rate intramolecular docking between N- and C-terminal domains of PrP(C), revealing a novel auto-inhib

252 The terminal domains of suprabasal keratins of the skin epit

253 analysis suggested that differences in the N-terminal domains of these polymerases are responsible fo

254 a direct physical interaction between the C-terminal domains of topoisomerase I (TopoI-CTDs) and the

255 We find that both the N- and C-terminal domains of TTP are involved in an interaction w

256 Mutations in the CaV1.3 alpha1 subunit N-terminal domain or in the CaMKII catalytic domain that l

257 he p150 subunit of human CAF-1 contains an N-terminal domain (p150N) that is dispensable for histone

258 phosphorylation at S54 and S73 within the N-terminal domain (Pdc-ND) followed by association with th

259 Here we report that the MARCH5 C-terminal domain plays a critical role in degradation of

260 e extensive set of interactions in the amino-terminal domain plays some role in the actions of physos

261 ad51 directly interacts with the Pol alpha N-terminal domain, promoting Pol alpha and delta binding t

262 at placed the cofactor-binding site in the C-terminal domain rather than the anticipated Rossmann fol

263 and a higher-order form that adopts carboxyl-terminal domain rearrangements.

264 nked through an invariant GGKGG motif to a C-terminal domain (referred to as Sde2-C).

265 is the active part of the protein, and the C-terminal domain regulates the activity.

266 0 could completely accommodate the GstDnaB C-terminal domain (residues 301-461).

267 We show that the disordered N-terminal domain (residues approximately 20-100) interact

268 hermodynamic stability measurements on the C-terminal domains (residues 90-231) of two PrP variants e

269 omain of three zinc fingers and a variable N-terminal domain responsible for recruiting cofactors.

270 r data show that, in the intermediate, the C-terminal domain retains a folded conformation that is si

271 cture of the Saccharomyces cerevisiae Stu2 C-terminal domain, revealing a 15-nm parallel homodimeric

272 Structural analysis of the C-terminal domain reveals a dimer with a lysine-rich surfa

273 The crystal structure of the GSDMB C-terminal domain reveals the structural impact of the ami

274 Structural insight into the C-terminal domain's architecture and localization mechanis

275 bioactive LN-511-E8 fragment carrying only C-terminal domains showed similar efficacy as full-length

276 ological inhibition of dynamin-2 or clathrin terminal domain (TD) ligand association, these strains e

277 Cdc48 consists of an N-terminal domain that binds UN and two stacked hexameric

278 Cleavage generates a C-terminal domain that contains a sterile-alpha-motif-like

279 tructure of CteB also reveals an accessory N-terminal domain that has high structural similarity to a

280 series of truncation mutants, we mapped a C-terminal domain that is necessary and sufficient for Cdr

281 forms a subdomain between the plug and the C-terminal domain, that 'clamps' the coiled coil of the pl

282 strated that transfer of the mycobacterial C-terminal domain to a standard F-ATP synthase alpha subun

283 ESCRT-III until it encounters the ordered N-terminal domain to destabilize the ESCRT-III lattice.

284 lasmic form of CCN3 interacted with the AR N-terminal domain to sequester AR in the cytoplasm of pros

285 change permitting the insertion of the LOK C-terminal domain to wedge apart the membrane and F-actin-

286 e propensity of the intrinsically unfolded C-terminal domains to drive pathological aggregation.

287 ing chloroplast transit peptide (cTP), and N-terminal domains to the ATPase, Rubisco recognition and

288 oid translocation and separation of C- and N-terminal domains upon transition from the basic orange t

289 In this study, the HTLV-1 capsid amino-terminal domain was found to provide distinct contributi

290 The interaction between the N- and C-terminal domains was not DNA-PKcs-dependent, and phospho

291 HD together with the DLX3 amino- or carboxyl-terminal domains was required for maximal inhibition of

292 valine 597 residues present in the Ldgp63 C-terminal domain were critical for binding with LdSec24(7

293 pendent condensation of the linker histone C-terminal domain, which is critical for stabilizing highe

294 catalytically inactive dioxygenase-related N-terminal domain, which is important for MCM loading, but

295 ment functions to provide stability to the C-terminal domain, which is necessary for lethal toxicity

296 ace includes the RNAP subunit alpha carboxyl-terminal domain, which is required for RNAP-ribosome int

297 Although SGTA's N-terminal domain, which mediates homodimerization and rec

298 The amino-terminal domain with a fold distinct among known TRP str

299 zed group of HRPKSs was found to contain a C-terminal domain with significant homology to carnitine O

300 on of ProP results from association of its C-terminal domain with the anionic lipid-enriched membrane