ライフサイエンスコーパス: terminal part

1 inal region and a rubredoxin domain in the C-terminal part.

2 domain and between Cys49 and Thr50 in the C-terminal part.

3 a long hydrophilic cytoplasmic tail in the C-terminal part.

4 synthetases, but differs completely in its C-terminal part.

5 ge ( approximately 250-residue) disordered C-terminal part.

6 s peptide, we have raised mAbs against its C-terminal part.

7 n its backbone that enables bending of its C-terminal part.

8 al binding site(s) probably exist in their C-terminal parts.

9 in the extracellular space, and a residual C-terminal part (130 kDa, p130) that remains integrated at

10 e of trifluoroethanol, CsTx-1 and the long C-terminal part alone (CT1-long; Gly-45-Lys-74) exhibit an

11 otein with 12 transmembrane domains in the N-terminal part and a long hydrophilic cytoplasmic tail in

12 utation and a covalent modification in the C-terminal part, and the assignment of a sequence of a pre

13 cycle via its C-terminal part, whereas its N-terminal part appears necessary for recruitment of some

14 Nevertheless, the C- and N-terminal parts are rich in basic amino acids, and these

15 of SelB recognizes this hairpin, while the N-terminal part binds GTP and tRNA in analogy with elongat

16 lucose cotransporter rbSGLT1 and its carboxy-terminal part, C5, which contains transmembrane helices

17 es a helix to strand conversion when N and C-terminal parts come together.

18 ated by its C-terminal sequence, while the N-terminal part comprises structural information and contr

19 ults of this investigation showed that the C-terminal part contains three thioether bridges connectin

20 a fourth site, K364, was identified in the C-terminal part exclusive of LEDGF/p75.

21 2 possesses protease activity, whereas the N-terminal part exhibits NTPase and RNA triphosphatase act

22 helix truncated, but not the form with the C-terminal part extended, bound ligands.

23 repair proteins (domains 1-3, MfdN), and a C-terminal part harboring motor activity (domains 4-7, Mfd

24 The posttranslationally modified N-terminal part has three domains that function to attach

25 The other, situated in the C-terminal part, has sequence similarity to the luciferin-

26 Mfd can be functionally dissected into an N-terminal part instrumental in recruiting DNA repair prot

27 Thus the N-terminal part is apparently required for CENH3 loading d

28 The larger, constitutively expressed C-terminal part is bound to the thick filament.

29 on and live-cell imaging, we show that the C-terminal part is crucial for Brd2 association with chrom

30 of Tim10 is a substrate sensor whilst its C-terminal part is essential for complex formation.

31 d that the F2 subdomain, in particular its C-terminal part, is crucial for the differential functiona

32 -arresting activity, bound directly to the C-terminal part of 14-3-3, outside of its phosphopeptide-b

33 Most remarkably, the terminal part of a phospholipid acyl chain is directly i

34 ORF1 (675 bp) encodes the C-terminal part of a Soj-like protein.

35 These studies indicate that the C-terminal part of AhpF and bacterial TrR have very simila

36 smaller (35 kDa) TrR protein occurs in the C-terminal part of AhpF; a stretch of about 200 amino acid

37 Different from mammalian homologs, the amino-terminal part of almost all AtTLPs has nucleocytosolic a

38 gnal peptide and pro-region of PC2 and the N-terminal part of alpha1-antitrypsin, called pro2alpha1.

39 We found that mutations within the amino-terminal part of alphaM1 had effects on activity and sel

40 observed that mutations within the carboxyl-terminal part of alphaM1 had effects on activity and sel

41 reading frame (ORF) which encodes the amino-terminal part of antizyme and overlaps the +1 frame (ORF

42 stence of a novel inhibitory domain in the N-terminal part of AR, which might play important roles in

43 l as a chimeric protein containing the amino-terminal part of AtCGL160 and Synechocystis sp. PCC6803

44 Our data indicate that the C-terminal part of Avo3, a subunit unique to TORC2, is clo

45 These findings indicate that the N-terminal part of BDV p56 is sufficient for receptor reco

46 AL4 DNA-binding segment indicated that the C-terminal part of BFCOL1 contained a potential transcript

47 d that a type I beta-turn structure at the C-terminal part of both ligands plays an important role in

48 ding dimerization domain indicate that the N-terminal part of C/EBPbeta prevents it from binding to t

49 etate inhibits C/EBPbeta by binding to the N-terminal part of C/EBPbeta, thereby disrupting the coope

50 l and central domains of Hipk2 and the amino-terminal part of C/EBPbeta.

51 The C-terminal part of CALM binds clathrin heavy chain, althou

52 inding of the Ca2+-pump domain to only the C-terminal part of CaM (b) dimer formation with fragments

53 gion has no known activity at present, the C-terminal part of CARM1 contains an autonomous activation

54 In both cases, the C-terminal part of Cdc37 is relevant for kinase binding, w

55 ealed that they shared a 14 cM region in the terminal part of chromosome 13q that included the locus

56 identified a 125 amino acid domain in the C-terminal part of Ci that mediates response to Cos2 inhib

57 ectively these data demonstrate that the NH2-terminal part of CRP1 that contains the alpha-actinin-bi

58 lexes (27 kBT), and is concentrated at the C-terminal part of CTD zippering.

59 d that CyoA-N-P2 (a construct with the amino-terminal part of CyoA fused to the Lep P2 soluble domain

60 ion of psbDI (coding for a 96-residue-long C-terminal part of D2) with sodium bisulfite.

61 g binding to the membrane focus in D1; the C-terminal part of D4; and strands beta1, beta4, and beta5

62 e mediated by the evolutionarily conserved N-terminal part of DBT.

63 on, and the 57K fragments were from the COOH-terminal part of DMP1.

64 Thus, the N-terminal part of Drosophila CENP-C is sufficient to recr

65 and the Ndc80 complex) network bind to the N-terminal part of Drosophila CENP-C.

66 er in the binding-site crevice than is the N-terminal part of E2.

67 etails of inter-domain interactions in the C-terminal part of eIF2D and sheds light on the possible r

68 roism spectroscopy indicated that the most C-terminal part of EMILIN-3 has a substantial alpha-helica

69 The N-terminal part of Era contains a conserved GTPase domain,

70 urin-dependent proteolytic cleavage of the N-terminal part of FcgRIIA, shifting neutrophils away from

71 other species, however, implying that the C-terminal part of FliG can function in conjunction with t

72 We show that the C-terminal part of FRQ, particularly the FRQ-FRH interacti

73 The N-terminal part of GEF115 contains a sequence motif that i

74 between Galpha13 and GEF115 depends on the N-terminal part of GEF115, and there was no synergistic ef

75 ng of the N-terminal part of GLUT7 and the C-terminal part of GLUT5.

76 ed a GLUT7-GLUT5 chimera consisting of the N-terminal part of GLUT7 and the C-terminal part of GLUT5.

77 n generates gp43, which corresponds to the C-terminal part of gp84.

78 ng that the highly conserved sequence of the terminal part of H2 is not critical for the conversion.

79 esses a nuclear export signal, whereas the C-terminal part of HDAC3 contributes to the protein's loca

80 fically hTSP-1; however, truncation in the N-terminal part of Hic decreases the binding activity, sug

81 end of the actin-binding domain 1 and the N-terminal part of hinge 1.

82 nt to a functional domain localized in the C-terminal part of histatin 5.

83 endosome interaction but dependent on the N-terminal part of HookA.

84 In contrast, the N-terminal part of Hot appears uniquely responsible for it

85 We present the crystal structure of a C-terminal part of HUWE1, including the catalytic domain,

86 F/SF2 from speckles by phosphorylating the C-terminal part of its RS domain.

87 Similar binding studies with the carboxy-terminal part of KCBP lacking the calmodulin-binding dom

88 e site in Kindlin-3 at tyrosine 373 in the N-terminal part of Kindlin-3 pleckstrin homology domain.

89 f KorB in vivo or in vitro showed that the C-terminal part of KorA between amino acid positions 68 an

90 A coiled-coil domain located in the N-terminal part of L-Sox5, and absent in Sox5, showed >90%

91 analyses, we identified two regions in the C-terminal part of L4 that contribute to an antiviral inte

92 , whereas A3H hapI-GKE associated with the C-terminal part of matrix and the N-terminal capsid domain

93 In contrast, Factor H, which binds to the N-terminal part of mature PspC molecules, did not interfer

94 me was mBE II-I BspHI, in which the carboxyl-terminal part of mBE II was exchanged for that of mBE I

95 analysis in S2 cells indicates that the COOH-terminal part of Megator without the coiled-coil region

96 with fusion proteins comprising either the N-terminal part of mesothelin/MPF (D1Ig), reported to be e

97 th defects in the MA (matrix), CA, and the N-terminal part of NC (nucleocapsid) sequences produced de

98 y the Gag nucleocapsid protein NC, and the N-terminal part of NC is most critical for this interactio

99 We found that the amino-terminal part of Net2p interacts with Fis1p, whereas the

100 ions, because point mutations in the carboxy-terminal part of nsP2 could make SIN and other alphaviru

101 The C-terminal part of nsP2 possesses protease activity, where

102 The C-terminal part of p300 containing the transactivating reg

103 have mapped a 20-amino acid region in the N-terminal part of p53 that is essential for its binding t

104 nic liposomes at pH 5, full-length and the C-terminal part of PB1-F2 assemble into amyloid structures

105 At pH >/= 7, the C-terminal part of PB1-F2 spontaneously switches to amyloi

106 The N-terminal part of Pdc-ND is likely located outside the ce

107 PA63 (the 63-kDa, C-terminal part of protective antigen) forms heptameric ch

108 s and synthetic peptides revealed that the N-terminal part of protein F contains the host-interacting

109 Copeptin, the C-terminal part of provasopressin, has emerged as a novel

110 es a three-dimensional fold similar to the C-terminal part of PrP, is also harmful to neuronal and ot

111 on of amide hydrogens) was detected in the N-terminal part of PrP90-231 fibrils, arguing against the

112 enic peptide that was derived from the amino terminal part of rat alpha3(IV)NC1 domain, and serum and

113 sful after using hybrid receptors with the C-terminal part of ReMAX replaced by that of Eix2.

114 or the first time that it is precisely the N-terminal part of ribosomal protein L11 that is required

115 unique N-terminal sequence followed by the C-terminal part of RIM2.

116 f nine ankyrin-like repeats present in the N-terminal part of RNase L.

117 SUMO interaction motifs (SIMs) in the N-terminal part of RNF4 tightly bind to SUMO polymers, and

118 conserved among most species in the carboxy-terminal part of S and analyzed their influence on the k

119 at interact with the RNA and membrane, the C-terminal part of S. pneumoniae Era was systematically de

120 In bacteria, the C-terminal part of SelB recognizes this hairpin, while the

121 asurements of pKb also demonstrated that a C-terminal part of sigma N, but not regions I or I + II, i

122 4 is important for granule initiation, the N-terminal part of SS4 serves to establish the correct gra

123 ion with fibrillins 1 were mediated by the N-terminal part of SS4.

124 Mutations within the carboxy-terminal part of SU had very little or no effect on biol

125 our epitopes (epitopes 1-4) located in the N-terminal part of TG2.

126 site 282 and the surrounding region in the C-terminal part of the 31-kDa domain.

127 The 16-kDa fragment corresponded to the N-terminal part of the 37-kDa peptide.

128 Mutations in the C-terminal part of the a' domain have significant effects

129 question of whether these mutations in the C-terminal part of the a' domain, which affect P4H assembl

130 domain within vIL-6 site I, mapped to the C-terminal part of the AB-loop and the beginning of helix

131 hange results in stable positioning of the N-terminal part of the activation domain of PGC-1alpha, fa

132 The C-terminal part of the adhesin consists of the receptor-bi

133 tophan residues in the beta-barrel and the N-terminal part of the alpha-helical domain become partial

134 hanging key amino acids located within the C-terminal part of the alpha2 domain and the alpha3 domain

135 n is mainly posttranslational and that the C-terminal part of the alpha2 domain and the alpha3 domain

136 Thus, the C-terminal part of the AP-4epsilon subunit plays an import

137 of the A, G, and H helix segments and the C-terminal part of the B helix are similar to those in nat

138 ontaining the TQQS-to-ETPV mutation in the N-terminal part of the betaG-betaH loop of VP1 showed not

139 terminus and contains p2, p10, and a large N-terminal part of the capsid (CA) domain; the other is lo

140 or protein interaction using as a bait the N-terminal part of the CEA encoding the binding site.

141 These results indicate that the N-terminal part of the CFTR R domain is dispensable for in

142 eS binding domain, which overlaps with the N-terminal part of the CheY2 binding domain (CheA(174-316)

143 ation region and by increasing that of the C-terminal part of the cleavage region.

144 by introduction of silent mutations in the N-terminal part of the coding region.

145 fragment of M(r) 47,000 containing the NH(2)-terminal part of the cofactor (amino acid residues 1-348

146 the formation of HEXIM1 oligomers via the C-terminal part of the coiled-coil or basic regions is cri

147 Importantly, mutations of the N-terminal part of the coiled-coil region abrogate the abi

148 n between the two complexes resided at the N-terminal part of the complex, adjacent to peptide residu

149 of ventricular myocytes is controlled by the terminal part of the conduction system known as the Purk

150 ide chains were detected in the middle and N-terminal part of the core protein.

151 5'-UTR plus simultaneous truncation of the N-terminal part of the CP impaired SPMV spread in foxtail

152 Sequence analysis also suggests that the N-terminal part of the E. coli reductase contains the FAD-

153 and R369H) are the first changes in the NH2-terminal part of the enzyme reported to cause the mut- p

154 the resultant EWS/ERG fusion protein, the N-terminal part of the ETS family protein ERG is replaced

155 the mutant yeast strains suggests that the N-terminal part of the eukaryotic and, in particular, yeas

156 Both interactions are localized to the N-terminal part of the EVI5 protein.

157 ) derived from a conserved sequence in the C-terminal part of the extracellular N terminus can activa

158 Sequence analysis of the C-terminal part of the F2 subdomain of K3 suggests that in

159 an additional mutation located in the amino-terminal part of the Fe-S protein at either position 44

160 Hence, the C-terminal part of the first extracellular loop not only d

161 also a short segment of 3(10) helix at the N-terminal part of the folded domain.

162 third transmembrane segment (S3b) and the N-terminal part of the fourth segment ((NT)S4) that harbor

163 ization reaction, where the N-terminal and C-terminal part of the fragment are fused into a macrocycl

164 criptional transactivation function in the N-terminal part of the glucocorticoid receptor (GR) appear

165 ed upon PPACK-binding, but residues in the N-terminal part of the heavy chain, the gamma-loop, and an

166 stallin domain, and one mutation is in the C-terminal part of the HSP27 protein.

167 ovel site is completely different from the C-terminal part of the human UEV domain that binds to P(S/

168 The results show that the carboxy-terminal part of the KCBP, with or without calmodulin-bi

169 gene rearrangement t(8;21) that fuses the N-terminal part of the key hematopoietic regulatory factor

170 maintaining these alleles and identify the N-terminal part of the leucine-rich repeat region as a pro

171 m requiring the DNA-binding domain and the N-terminal part of the ligand-binding domain.

172 ) sequence in Kir channels, located in the N-terminal part of the linker between the two transmembran

173 sertion of a 16-residue spacer between the C-terminal part of the loop sequence (i.e. between residue

174 Initially, the Ca2+ binds to the N-terminal part of the loop, thus generating a rigid link

175 This involves the C-terminal part of the Ltr proteins, which control specifi

176 betaHis81 and two amino acids from the NH(2)-terminal part of the MHC bound peptide coordinate Ni(2+)

177 Phosphorylation of sites in the NH2-terminal part of the microtubule-binding domain by glyco

178 ed within a 140-residue-long region of the C-terminal part of the middle region of Leu3p.

179 deletion mutants of C/EBPbeta lacking the N-terminal part of the molecule are able to bind to the PP

180 2 monoclonal antibodies (mAbs) against the N-terminal part of the molecule but not by mAb 6H4, which

181 The isoform-dependent N-terminal part of the molecule forms an elastic connectio

182 e, likely in a transmembrane form with the C-terminal part of the molecule inserted into the cytoplas

183 hand, antibodies directed against the amino-terminal part of the molecule, including the fusion pept

184 cant variability in the orientation of the C-terminal part of the molecule, the region expected to be

185 l the epsin endocytic motifs reside in the C-terminal part of the molecule, these results suggest tha

186 oop located between beta7 and beta8 in the N-terminal part of the molecule.

187 n additional ubiquitin binding site in the C-terminal part of the molecule.

188 G(M1) gangliosidosis patients found in the C-terminal part of the molecule.

189 P results in a significant ordering of the N-terminal part of the molecule.

190 can propagate [URE3] in the absence of the C-terminal part of the molecule.

191 or C-S bonds also led to the release of the terminal part of the monolayer in a predictable manner.

192 the epitope for mAb 5F1 is created by the N-terminal part of the N domain, between residues 1 and 14

193 Thus, the amino-terminal part of the nucleocapsid protein is probably in

194 tion of a truncated CFTR protein lacking the terminal part of the nucleotide-binding domain 1 (NBD1)

195 recognized by the virus proteinase in the N-terminal part of the open reading frame 1 (ORF1) polypro

196 iophysical techniques and showing that the N-terminal part of the peptide may be modified without cha

197 Repositioning of the N-terminal part of the peptide on CyP.TS formation becomes

198 The structure of the N-terminal part of the peptides is variable and interacts

199 e periplasmic displacement of 3-4 A of the C-terminal part of the periplasmic ligand-binding domain u

200 how that a 49-mer peptide derived from the C-terminal part of the Phe521Leufs chain is deposited as f

201 nt upon configurational flexibility in the C-terminal part of the polypeptide chain to ensure passage

202 multiple virus passages suggests that the N-terminal part of the prM protein, a specific site in the

203 ionally relevant PC processing site in the N-terminal part of the pro-domain that is important for th

204 age, which requires a free cysteine in the C-terminal part of the protein and results in the producti

205 atment of P41 cleaves the same bond in the C-terminal part of the protein as is cleaved in the P46-->

206 osphate isomerase barrel is covered by the C-terminal part of the protein containing an additional [4

207 ins a conserved GTPase domain, whereas the C-terminal part of the protein contains an RNA- and membra

208 The C-terminal part of the protein does not associate with eit

209 The C-terminal part of the protein is best conserved and most

210 xtended variants of nsP2 revealed that the C-terminal part of the protein is indispensable for helica

211 ng DNA in the presence of ATP, and the NH(2)-terminal part of the protein was found to mediate its lo

212 cids with an ATPase-helicase domain in the N-terminal part of the protein, a central spacer domain, a

213 jor region of sequence variation is in the C-terminal part of the protein, a region with DNA-binding

214 uncated allele of beta-catenin without the N-terminal part of the protein, give rise to embryos whose

215 sephosphate isomerase barrel formed by the N-terminal part of the protein, which contains the [4Fe-4S

216 a dimer with a conserved interface in the N-terminal part of the protein.

217 the DNA-binding ETS domain of FLI1 in the C-terminal part of the protein.

218 ion comprising a 20-residue stretch in the C-terminal part of the protein.

219 ine esterase) activity is localized on the N-terminal part of the protein.

220 and that the CSA-binding site lies in the N-terminal part of the protein.

221 The toxin-binding site is located in the C-terminal part of the PTPvarsigma ectodomain and includes

222 .6-kb fragment was predicted to encode the C-terminal part of the putative NS4b, the entire NS5a, and

223 sistent with weak interactions between the N-terminal part of the RBD and the kinase.

224 re kinase activity and is conferred by the N-terminal part of the receptor.

225 monstrated for the first time that the amino-terminal part of the Rieske Fe-S protein encompassing re

226 Mutations were clustered in the carboxy-terminal part of the rod domain, which is critical for f

227 e localization of the COU-1 epitope to the N-terminal part of the rod domains.

228 phosphorylation of ASF/SF2 by SRPK1 to the N-terminal part of the RS domain - a property essential fo

229 uncoupled FPR mutants were located in the N-terminal part of the second transmembrane domain (S63W a

230 ubiquitin is highly polarised towards the N-terminal part of the sequence and involves a nucleus of

231 irpin stabilises local interactions in the C-terminal part of the sequence, resulting largely in a de

232 The terminal part of the small intestine and large intestine

233 Transient helix I comprises the most N-terminal part of the SNARE motif, transient helix II ext

234 In the full-length molecule, the C-terminal part of the tail has an additional bend taking

235 n the N-terminal F3 FERM subdomain and the C-terminal part of the talin rod contributes to an autoinh

236 amino acid peptide located near the carboxyl-terminal part of the tenascin-C molecule.

237 are located adjacent to each other in the N-terminal part of the TG2 molecule.

238 ia a paddle-shaped motif that includes the C-terminal part of the third transmembrane segment (S3b) a

239 ion encompassing Cys-1448 derived from the N-terminal part of the triple-helical domain.

240 Copeptin, the C-terminal part of the vasopressin prohormone, is secreted

241 ely 40-amino acid residue D repeats in the C-terminal part of these proteins.

242 Importantly, the N-terminal part of this alpha-helix, from Phe(93) to Thr(9

243 t(12;16) translocation that fuses the amino-terminal part of TLS to the entire coding region of CHOP

244 Deletion of the C-terminal part of TRAM2 inhibits type I collagen synthesi

245 The C-terminal part of TRAM2 interacts with the Ca(2+) pump of

246 the UbiK protein forms a complex with the C-terminal part of UbiJ, another UQ biogenesis factor we p

247 it proton transport only when fused to the N-terminal part of UCP1 (chimera U1U2).

248 In contrast, the C-terminal part of Ure2p cannot be converted to the prion

249 region around residue 224 and more of the C-terminal part of Ure2p restore prion-inducing ability.

250 Homologies of the N-terminal part of VirB1 to bacterial transglycosylases su

251 n and factor H, and that it recognized the C-terminal part of Vn (aa 352-362).

252 Mutation analysis showed that the C-terminal part of Vpr binds to the C-terminal portion of

253 18 N-terminal domain can interact with the N-terminal part of Vps11 and also binds to lipids.

254 required for binding to XAP3, while the NH2-terminal part of XAP3 is necessary for binding to X.

255 NtPEX5 fusion proteins, consisting of the N-terminal part of yeast Pex5p and the C-terminal region o

256 indicate that, instead of this domain, the N-terminal part of Yos9 including the mannose 6-phosphate

257 e domain is inserted in between the N- and C-terminal parts of a homologous domain.

258 ies of point mutants show that both N- and C-terminal parts of each protein are important for stabili

259 The C-terminal parts of Ent1 and Sla2 bind redundantly to acti

260 uence of F1 binds in an inhibitory mode to N-terminal parts of exogenous and endogenous fibronectin w

261 A crystal structure of the middle and C-terminal parts of FliG shows two globular domains connec

262 The crystal structure of the middle and C-terminal parts of FliG shows two globular domains joined

263 sent study using antibodies against N- and C-terminal parts of human melanopsin, confocal microscopy

264 Several mutations affecting the mid- to C-terminal parts of MinD led to a protein probably unable

265 N- and C-terminal parts of the G. lamblia acetyl-CoA synthetase s

266 The N-terminal and C-terminal parts of the LRP-515 subunit are resistant and

267 tein to two critical residues in the carboxy-terminal parts of the molecules.

268 maritima, which encompasses the middle and C-terminal parts of the protein (termed FliG-MC).

269 he interface of the core (DNA-binding) and N-terminal parts of the protein a slow conformational exch

270 Fragment ions derived from both N- and C-terminal parts of the protein are equally unaffected by

271 nal information between the N-terminal and C-terminal parts of the protein.

272 s of deletion mutants lacking either N- or C-terminal parts of the RGS9 molecule.

273 a2+-binding sites are located in the C and N-terminal parts of the S100P molecule, respectively.

274 essential for these activities, the N- and C-terminal parts of the Streptococcus pneumoniae Era - Era

275 n atypical FERM domain, whereas the N- and C-terminal parts of the talin rod include a series of alph

276 ixth transmembrane domains near the N- and C-terminal parts of the third cytoplasmic loop did not res

277 mains of 250-270 amino acids in the N- and C-terminal parts of their sequences.

278 The N-terminal parts of these multidomain proteins contain six

279 A helical tripod, the carboxy-terminal parts of three heavy chains, projects inward fr

280 g region (215-amino acids or 215aa), 103aa N-terminal part or a smaller N-terminal region (34aa), eac

281 of full-length syndapins, but not the NH(2)-terminal part or the SH3 domains alone, had a strong eff

282 the polalpha catalytic domain without the C-terminal part (p180DeltaN-core) possessed a much higher

283 -160) sequence with PCNA revealed that the N-terminal part (residues 141-152) of the above peptide is

284 P(C) (HuPrP) fold features an unstructured N-terminal part (residues 23-124) and a well-defined C-ter

285 d domain formed by two closely intertwined C-terminal parts (residues 33-76), and two highly mobile t

286 e Era was systematically deleted while the N-terminal part, responsible for the GTPase activity of th

287 us, it is shown that a modification in the C-terminal part significantly reduces the adhesion of cell

288 However, the N-terminal part (Suc-Ala) becomes repositioned in the TS s

289 at links its N-terminal WD40 domain to the C-terminal part that contains the exonuclease, with a 2:1

290 to the helicase domain, RecQ4 has a unique N-terminal part that is essential for viability and is con

291 cmB), a middle P-loop GTPase domain, and a C-terminal part that is homologous to the large subunit of

292 Caspase-8 cleaves Bid, and the COOH-terminal part translocates to mitochondria where it trig

293 it of bc1 complexes contains in its carboxyl-terminal part two highly conserved hexapeptide motifs (b

294 udokinase domain linker indicated that its N-terminal part was essential for interaction of JAK2 with

295 A "latch" region in the N-terminal part was observed to close over the topoisomera

296 To test whether CENP-C's N-terminal part was sufficient to recruit KMN proteins, we

297 tromeres throughout the cell cycle via its C-terminal part, whereas its N-terminal part appears neces

298 , they differ in the length of their carboxy terminal part, which in pCP-2 has the composition CUB1,

299 large insert in the RecA2 domain, and the C-terminal part, which includes winged-helix, ratchet, and

300 es E. coli switch protein FliN only in its C-terminal part, while an additional N-terminal domain is