ライフサイエンスコーパス: terpene

1 y with limonene, a commonly occurring indoor terpene.

2 unt of four terpenes out of seven quantified terpenes.

3 cle fusion and ectopic expression of certain terpenes.

4 s of complex plant products including higher terpenes.

5 oengineering metabolic pathways for specific terpenes.

6 for approximately 97% of the total volatile terpenes.

7 encoded proteins glucosylate a diversity of terpenes.

8 that are precursors of all major classes of terpenes.

9 ols, 2-ketones, aldehydes, ethyl esters, and terpenes.

10 eparation from the corresponding terrestrial terpenes.

11 penoids are a relatively rare class of plant terpenes.

12 ule and utilizes both cofactors for building terpenes.

13 rings, a pattern shared by a number of other terpenes.

14 ed spectroscopy, even in complex mixtures of terpenes.

15 la consists of esters (33%), alcohols (27%), terpenes (18%) and others (21%).

16 sulfur compounds; bacuri is characterized by terpenes (41%), non-terpenic alcohols (24%), esters (15%

17 nto the elaborate polycyclic ring systems of terpenes, a sequence that is often difficult to emulate

18 nation of GC-MS and NMR in comparison to the terpenes accumulating in planta.

19 del also avoids food treated with one of the terpenes, after having experienced gastrointestinal mala

20 eas for acid hydrolysis the area of released terpene aglycone did not exceed 1.3% of total peak area

21 ic hydrolysis 85-91% of total peak areas was terpene aglycone, whereas for acid hydrolysis the area o

22 any grape-derived volatile compounds such as terpene alcohols and C13-norisoprenoids in wine, althoug

23 eoxy 1-O-glucosides of important phenols and terpene alcohols in excellent yields (85-96%) has been d

24 beta-damascenone but had no impact on other terpene alcohols or beta-ionone.

25 he 2,3-dideoxy 1-O-glucosides of phenols and terpene alcohols were more effective in their antimicrob

26 e in content of various sulfurous compounds, terpene alcohols, ketones and pyrazines was noted.

27 whole fruit also contained higher levels of terpene alcohols.

28 configuration changed during storage for the terpene alcohols.

29 ounds (alcohols, C6 compounds, ethyl esters, terpenes, aldehydes, acids, lactones, volatile phenols a

30 mined in pistachio oil and it was found that terpenes, aldehydes, and alcohols were the most abundant

31 es in virtually every natural product class: terpenes, alkaloids, prostaglandins, macrolides, and tet

32 When starting from sterically hindered terpenes, allenylphosphonates were also easily obtained

33 ate the oxidation of VOCs, in particular the terpene alpha-pinene, under atmospherically relevant con

34 The terpenes alpha-thujene, sabinene, gamma-terpinene and be

35 SANDPUMA algorithm, improved predictions for terpene and ribosomally synthesized and post-translation

36 ne function analyses to characterize gene-to-terpene and terpene pathway scenarios in a self-pollinat

37 synthetic enzymes for production of volatile terpenes and benzoxazinoids.

38 ch showed the highest contents of pyrazines, terpenes and esters, while teff, buckwheat and rice flou

39 The biosynthesis of terpenes and fatty acid aroma precursors also increased

40 Plants produce numerous terpenes and much effort has been dedicated to the ident

41 usly hidden degradation reactions running in terpenes and natural resins exposed to artificial aging

42 Twenty-one terpenes and one ester were identified from the exhaled

43 ospheric conditions for the autooxidation of terpenes and other unsaturated hydrocarbons; it shows th

44 processing, most of the naturally occurring terpenes and phenylpropanoids were better preserved in H

45 pecies according to chemical classes such as terpenes and sulfur compounds.

46 y be enhanced by the presence of mixtures of terpenes and that the acquisition of new functions by te

47 production of cv Royal Gala floral-specific terpenes and TPS genes was observed in the fruit of some

48 s, 8 hydrocarbons, 14 carbonyl compounds, 17 terpenes, and 6 other compounds.

49 of defensive metabolites such as alkaloids, terpenes, and glucosinolates have been studied extensive

50 dehydration grapes were richer in total free terpenes, and the resulting wines contained greater amou

51 sis (PLS-DA), the purees may be allocated to terpene- and lactone-rich ('SH-5'), ester-containing ('C

52 Terpenes are an important and diverse class of secondary

53 Despite their structural diversity, volatile terpenes are generally produced from a small number of c

54 Terpenes are specialized plant metabolites that act as a

55 Terpenes are structurally diverse natural products invol

56 Terpenes are the largest class of small-molecule natural

57 Terpenes are the main group of secondary metabolites, wh

58 However, little is known about how terpenes are transported within the cell and from the ce

59 cyclohexene, acting as surrogate for cyclic terpenes, are followed as protonated species (CI)H(+) us

60 nic aerosol (SOA) originating from isoprene, terpenes, aromatics, and sesquiterpenes.

61 We review here the status of terpenes as a specialty biofuel and discuss the potentia

62 ide range of aroma qualities associated with terpenes as well as to concentration, synergistic or mas

63 ing copolymerization of propylene oxide with terpene-based cyclic anhydrides catalyzed by chromium, c

64 liverworts accumulates structurally diverse terpenes believed to serve in deterring disease and herb

65 easing different types of odorant molecules (terpenes, benzenic compounds and lipid derivatives).

66 DMS coating showed higher relative areas for terpenes (beta-citronellol, geraniol, linalool and alpha

67 istent mechanistic questions in the world of terpene biosynthesis and also provide examples of genera

68 we present unexpected plasticity in volatile terpene biosynthesis by showing that irregular homo/nort

69 However, terpene biosynthesis in glandular trichomes of tomato (S

70 es insight into the biochemical evolution of terpene biosynthesis in the glandular trichomes of Solan

71 Terpene biosynthesis in tomato glandular trichomes has b

72 strategy inspired by the logic of two-phase terpene biosynthesis in which powerful C-C bond construc

73 ransfer reactions postulated to occur during terpene biosynthesis is assessed and guiding principles

74 Plant terpene biosynthesis is regulated at multiple levels, le

75 eranylgeranyl reductase (CHLP), an enzyme of terpene biosynthesis that supplies the hydrocarbon chain

76 S) are situated at critical branch points in terpene biosynthesis, producing the precursors of the di

77 The pivotal enzymes for terpene biosynthesis, terpene synthases (TPSs), had been

78 yclase and oxidase) as loosely modeled after terpene biosynthesis.

79 yme with two-domain TPSs of mono- and sesqui-terpene biosynthesis.

80 e identification and characterization of the terpene biosynthetic genes.

81 The pool of abundant chiral terpene building blocks (i.e., "chiral pool terpenes") h

82 non-mevalonate biosynthesis of the universal terpene building blocks isopentenyl diphosphate and dime

83 streamline the synthesis of polyhydroxylated terpenes by minimizing protecting group and redox adjust

84 oducts, e.g. capsaicinoids, cannabinoids and terpenes, by highlighting challenges and opportunities i

85 d sustainable energy has identified specific terpenes capable of supplementing or replacing current p

86 A four-step synthesis of the antimalarial terpene cardamom peroxide, a 1,2-dioxepane-containing na

87 A via 10 net oxidations from the ubiquitous terpene (+)-cedrol.

88 iphatic hydrocarbons, single ring aromatics, terpenes, chlorinated solvents, formaldehyde, and acrole

89 rs, ketones, acids, amines, hydrocarbons and terpenes, chosen as representative components of a wide

90 Sesterterpenoids are a rare terpene class harboring untapped chemodiversity and bioa

91 howed relatively higher levels of ketone and terpene compounds with 'woody' and 'cereal-like' sensory

92 ily fitted to regression models for some key terpene compounds.

93 Grape berry terpene concentrations may vary at different stages of b

94 ies and lower growth rates, C : N ratios and terpene concentrations.

95 Essential oils and their oxygenated terpene constituents possess potent antimicrobial proper

96 tiple levels, leading to wide variability in terpene content and chemistry.

97 Aldehyde and terpene content can be used to characterize cultivars.

98 The average total terpene content increased five times during the alpine r

99 The terpene content of milk and cream made from milk obtaine

100 Skin showed high terpene content while pulp had higher amount of lactones

101 ch can be exploited in breeding for elevated terpene content.

102 ulation of a specific enantiomer of a chiral terpene could be enhanced relative to the other enantiom

103 These four terpenes could be used, as indicators, to show that milk

104 Puzzlingly, no dedicated terpene cyclase is found in the gene cluster identified

105 ogue of iridoid synthase (OeISY), an unusual terpene cyclase that couples an NAD (P)H-dependent 1,4-r

106 synthase in A. fumigatus as a membrane-bound terpene cyclase.

107 ces of social amoebae reveal the presence of terpene cyclases (TCs) in these organisms.

108 ases and cyclases which clearly separate the terpene cyclases from other terpene synthases having hig

109 t since it has been proposed that many plant terpene cyclases may have arisen from bacterial diterpen

110 to that of the alpha domains of modern plant terpene cyclases, a result that is of interest since it

111 twork of residues that controls the onset of terpene cyclization in Artemisia annua.

112 The tail-to-head terpene cyclization is arguably one of the most complex

113 is followed by an oxidative dearomatization/terpene cyclization sequence to build up the stereochemi

114 The emergence of terpene cyclization was critical to the evolutionary exp

115 he first example of a P450 that can catalyze terpene cyclization, most likely via initial oxidation o

116 Terpenes derived from the same biosynthetic pathway had

117 ts as a viable agronomic solution for future terpene-derived biofuels.

118 Oleuropein, a terpene-derived glycosylated secoiridoid biosynthesized

119 total syntheses which themselves use small, terpene-derived materials as building blocks.

120 As a practical application, terpene-derived primary alcohols were converted into sem

121 With terpene-derived substrates, similar trends in reactivity

122 The terpenes did not influence the sensorial quality of the

123 attern of polyketide phenol nucleophiles and terpene diphosphate electrophiles.

124 The primary drivers of terpene diversification are terpenoid synthase (TS) "sig

125 atural products, we investigate the basis of terpene diversity through analysis of multiple sequenced

126 or key events that are likely to have shaped terpene diversity.

127 ne hydrocarbon (2-methyl 2-pentene), and one terpene (DL-limonene).

128 In contrast, a bouquet of terpenes, dominated by sesquiterpenes including beta-bar

129 (e.g. terpinene) and minor cyclic oxygenated terpenes (e.g. thymol), may contribute to antioxidant po

130 Food treated with the terpenes elicited avoidance responses in the cooccurring

131 The average total terpene emission rate from the use of herbs and pepper d

132 miana leaf extracts suggested that increased terpene emissions may be attributed to proteasome malfun

133 scovered, which enhance catechin production, terpene enzyme activation, and stress tolerance, importa

134 This study aimed to investigate terpene evolution in grape berries from four weeks post-

135 Thus, mastic oil, as a combination of terpenes, exerts growth inhibitory effects against colon

136 Plant-derived volatile compounds such as terpenes exhibit substantial structural variation and se

137 not led to even the simplest members of this terpene family.

138 ural products from an abundant and renewable terpene feedstock.

139 Terpenes followed by higher alcohols and esters were the

140 stems may enhance the capacity to synthesize terpenes for bark beetle resistance, chemical feedstocks

141 xamples of general reactivity principles for terpene-forming (and other) carbocation rearrangements.

142 nthases results in the enormous diversity of terpenes found in nature.

143 elective pressure, while the small number of terpenes found in the fruit of modern cultivars may be r

144 s to build the bridging bicyclo[4.3.1]decane terpene framework.

145 Regarding the first reaction, oxidative terpenes, free fatty acids and carotenoids degradation p

146 e are few examples of commercial recovery of terpenes from plants because of low yields.

147 This big hydrophobic terpene functional group affects the codon recognition p

148 of these compounds is present as nonvolatile terpene glycosides.

149 terpene building blocks (i.e., "chiral pool terpenes") has long served as a starting point for the c

150 es responsible for the chemical diversity of terpenes have yet to be described.

151 Unsaturated terpenes having a cyclohexadiene structure (e.g. terpine

152 tion of a highly unusual aromatic polyketide-terpene hybrid intermediate which features an unpreceden

153 rs strongly influence volatile formation and terpene hydrocarbons are claimed to be suitable markers

154 e content of several aldehydes, alcohols and terpene hydrocarbons while an increase in content of var

155 d on the individual reaction pathways of the terpenes hydroxydammarenone and abietic acid as well as

156 The main terpenes identified and semi-quantified were the monoter

157 The berries were found to contain 44 terpenes identified by GCxGC-TOFMS.

158 t eucalyptol was the most abundant bioactive terpene in analysed berries (12.4-418.2 mug/L).

159 monoterpenes, sesquiterpenes, and oxygenated terpenes in 2D space, and thus orthogonality, could be a

160 Direct measurement of volatile terpenes in cultures of D. discoideum revealed essential

161 a development-specific function of volatile terpenes in D. discoideum.

162 Terpenes in grapes at harvest might not necessarily be s

163 titute an important yet overlooked source of terpenes in indoor air.

164 r semi-quantitative analysis of aroma-active terpenes in liquid food matrices.

165 anges (Citrus sinensis) primarily accumulate terpenes in peel oil glands, with d-limonene accounting

166 ue features of the biosynthetic apparatus of terpenes in plants that facilitate the production of lar

167 The synthesis of volatile terpenes in plants typically proceeds through either ger

168 f monomeric and oligomeric flavan-3-ols, and terpenes in the wines.

169 or users owing to the reaction of ozone with terpene ingredients.

170 vidence of an interaction between NtPDR1 and terpenes is lacking.

171 This set of terpenes is synthesized by multiproduct enzymes, with ei

172 Although total synthesis of such terpenes is widely studied, synthetic strategies that al

173 aroma compounds, including esters, alcohols, terpenes, lactones, acids, carbonyl compounds, and volat

174 Such gene-to-terpene landscapes associated with different tissues are

175 ripened fruits; whereas, an increase in the terpene level during ripening appears to be independent

176 containing lemon essential oil incorporated terpenes (limonene, gamma-terpinene, p-cymene and alpha-

177 All the regular cleaning agents emitted terpenes, mainly limonene and linalool.

178 f a key intermediate to many potent Illicium terpenes make chemical synthesis the unquestionable meth

179 oxidant potential of major cyclic oxygenated terpenes (menthol and menthone) are conflicting.

180 In this review, recent advances regarding terpene metabolic engineering are highlighted, with a sp

181 /CYP gene pairs for previously characterized terpene metabolic gene clusters and demonstrate new func

182 enome editing, have begun to elucidate plant terpene metabolism, and such information is useful for b

183 regulation for these branch point enzymes of terpene metabolism.

184 ined the photo-oxidation and aging of boreal terpene mixtures in the SAPHIR simulation chamber.

185 Several terpene modules could be assigned to previously identifi

186 Thanks to the grafted terpene moieties, some of these new conjugates demonstra

187 he family Xylariaceae, producing a series of terpene molecules, including 1,8-cineole.

188 The genes that produce terpene molecules, such as 1,8-cineole, have been little

189 of cyclobutane-formation, in particular, for terpene natural products.

190 passes sterically bulky enynamines including terpene natural products.

191 We recently characterized a gene-terpene network that is associated with artemisinin bios

192 dehydes, alcohols, esters, ketones, phenols, terpenes, norisoprenoids, and pyridines.

193 (R-(+)-limonene), p-cymene, and camphene (a terpene not present in the initial gas mixture) increase

194 Terpene nucleosides are rare in nature, and 1-TbAd is kn

195 rom all sorts of biomass, from carbohydrate, terpenes, or oleochemical sources.

196 , Neelum contains the highest amount of four terpenes out of seven quantified terpenes.

197 ted for measurement together with the common terpene oxidation products formaldehyde, 4-acetyl-1-meth

198 The structurally intriguing terpenes pallambins C and D have been assembled in only

199 ees Brix) led to volatile profiles richer in terpenes, particularly linalool and geraniol.

200 analyses to characterize gene-to-terpene and terpene pathway scenarios in a self-pollinating variety

201 Thus, this intersection of nucleoside and terpene pathways likely arose late in the evolution of t

202 In general, C6 compounds, alcohols, terpenes, phenols and C13-norisoprenoids in Syrah showed

203 ermine the role of IDS and to create altered terpene phenotypes for assessing the defensive role of t

204 ing enabled selection of Strecker aldehydes, terpenes, phenylpropanoids, fatty acid derivatives and c

205 and the best ways to sink existing pools of terpene precursors are discussed.

206 ural products can be traced to simple linear terpene precursors, the details of the enzymatic cycliza

207 nalyzed the volatile dietary phytochemicals (terpenes) present in mastic oil extracted from the resin

208 nctional enzymes suggests that the remaining terpenes produced in floral and vegetative and fruit tis

209 vegetative tissues were the primary sites of terpene production in cv Royal Gala.

210 re we report on the application of a modular terpene production platform in the characterization of t

211 duplicated genes, and AcTPS1 expression and terpene production were observed only at low levels in d

212 ) for investigating the pathways of volatile terpene production.

213 lleled the accumulation of the corresponding terpene products (germacrene D and (E)-beta-caryophyllen

214 The establishment of the terpenes profile of berries of different blue honeysuckl

215 wifruit (Actinidia) species with contrasting terpene profiles were compared to understand the regulat

216 racterised by higher averaged peak areas for terpenes, pyrazines and straight-chained aldehydes.

217 The olfactory detection threshold of this terpene reminiscent of mint was 0.9mug/L in model hydroa

218 pene synthases that produce cyclic or linear terpenes, respectively.

219 case by substituting the naturally occurring terpene (S)-beta-pinene for benzene and evaluating the 2

220 nly 15 steps from the commercially available terpene (S)-pulegone.

221 tion of heterologous nonvolatile hydrophobic terpenes, such as triterpene sapogenins, from engineered

222 o be a very suitable technique for detecting terpenes, sugars, organic acids, aminoacids and osmolite

223 , including aromatic amino acids and acyclic terpenes, suggesting a reduction of metabolic flexibilit

224 terpenes called rhizathalenes by the class I terpene synthase (TPS) 08 in roots of Arabidopsis thalia

225 s could be assigned to previously identified terpene synthase (TPS) activities that included members

226 Four of these putative trans-IDSs exhibited terpene synthase (TPS) activity when heterologously expr

227 trans-prenyltransferase (PT) and N-terminal terpene synthase (TPS) domains.

228 hase (GLS) belonging to the e/f clade of the terpene synthase (TPS) family and two Fabaceae GLSs that

229 apple (Malus domestica) contains 55 putative terpene synthase (TPS) genes, of which only 10 are predi

230 ery and mechanistic analysis of golden larch terpene synthase 8 (PxaTPS8), an unusual diterpene synth

231 3) whose members have a characteristic alpha terpene synthase alpha-helical fold.

232 ugh advances in cereal genome annotation and terpene synthase characterization that likewise enable d

233 s are produced in our system by changing the terpene synthase enzyme.

234 rgy surfaces, but also for the mechanisms of terpene synthase enzymes and their evolution.

235 ortance of inherent substrate reactivity for terpene synthase enzymes is discussed, with a focus on r

236 Mutations of residues outside of the alpha terpene synthase fold are important for acquisition of F

237 T1, SlCPT2 and SlCPT6) are closely linked to terpene synthase gene clusters.

238 esources, we identified seven V. officinalis terpene synthase genes (VoTPSs), two that were functiona

239 , the phylogenetic analysis revealed the two terpene synthase genes as primitive genes that might hav

240 a HMMER search tool to identify 17 putative terpene synthase genes from M. polymorpha transcriptomes

241 late E7406B, we were able to identify 11 new terpene synthase genes.

242 ra of rhizobia were found to have homologous terpene synthase genes.

243 n of (S)-beta-citronellol commences with the terpene synthase GES1 catalyzing the irreversible conver

244 wledge, this is the first documentation of a terpene synthase involved in the synthesis of a linear t

245 rgent evolution, mutational analysis of this terpene synthase revealed an active site asparagine crit

246 urprising finding of an atypical class I (di)terpene synthase that acts on CPP to produce the abietan

247 ene synthase (ZIS) gene encoding a cytosolic terpene synthase that has been shown to possess both ses

248 ism in the promoter of the gene encoding the terpene synthase TPS2 with this QTL Biochemical characte

249 taxadiene synthase (TXS), the model class I terpene synthase, which simulates the initial catalytic

250 ing gene and protein expression of A. arguta terpene synthase1 (AaTPS1) and correlated with an increa

251 Actinidia chinensis terpene synthase1 (AcTPS1) was identified as part of an

252 Here, we expressed maize (Zea mays) terpene synthase10 (ZmTPS10), which produces (E)-alpha-b

253 isogenic lines enabled the identification of terpene synthase21 (ZmTps21) on chromosome 9 as a beta-c

254 e show that all four selected genes, the two terpene synthases (TPS10 and TPS14) and the two cytochro

255 has been well studied, with most if not all terpene synthases (TPSs) being identified.

256 To identify terpene synthases (TPSs) involved in the production of t

257 lycopersicum; Solanaceae) contains genes for terpene synthases (TPSs) that specify the synthesis of m

258 he pivotal enzymes for terpene biosynthesis, terpene synthases (TPSs), had been described only in pla

259 of a large gene family (with 20 members) for terpene synthases (TPSs).

260 -dependent cyclization cascades catalyzed by terpene synthases (TSs).

261 well as structural comparisons with diverse terpene synthases and cyclases which clearly separate th

262 families of conifer defense metabolism, the terpene synthases and cytochrome P450s.

263 s, not related to previously described plant terpene synthases and only distantly so to microbial-typ

264 Class I terpene synthases generate the structural core of bioact

265 rly separate the terpene cyclases from other terpene synthases having highly alpha-helical structures

266 Substrate promiscuity of terpene synthases provides organism access to novel chem

267 Promiscuity of terpene synthases results in the enormous diversity of t

268 challenges for the functional assignment of terpene synthases that construct the carbon skeletons of

269 (E)-beta-farnesene synthase (BFS), a pair of terpene synthases that produce cyclic or linear terpenes

270 ata were used to identify eight putative (di)terpene synthases that were then characterized for their

271 into the evolutionary relationship of fungal terpene synthases to those in plants and bacteria and fu

272 and terpenoid compounds, including putative terpene synthases, were first identified by mining publi

273 ases and only distantly so to microbial-type terpene synthases.

274 scades and promiscuity mechanisms of class I terpene synthases.

275 acilitate the functional assignment of novel terpene synthases.

276 rase mechanism of UbiX resembles that of the terpene synthases.

277 es these enzymes in a noncanonical family of terpene synthases.

278 bolism, cell signalling, electron transport, terpene synthesis and other extracellular activities.

279 Here we implement a two-phase terpene synthesis strategy to achieve enantiospecific to

280 rees of oxidation were prepared by two-phase terpene synthesis.

281 nine ketones, five esters, eight acids, ten terpenes/terpenoids, ten furans/furanones, two pyrroles,

282 of genes for specialized metabolites such as terpenes that act as chemical defence and provide unique

283 f sap was studied and a total seven selected terpenes that are alpha-pinene, alpha-phellandrene, (+)-

284 Cleaning agents often emit terpenes that react rapidly with ozone.

285 Focusing on the terpenes, the largest class of plant natural products, w

286 of complex natural products, including many terpenes themselves.

287 This review highlights 21st century terpene total syntheses which themselves use small, terp

288 These results validate two-phase terpene total synthesis as not only an academic curiosit

289 Phospholipids (PL) and terpenes (TP) may serve as enhancing agents in absorptio

290 t conclusive for a role of vesicle fusion in terpene transport, they do show a strong interaction bet

291 rape genome for sequences with similarity to terpene URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASES (UGTs)

292 particular, monomers such as carbon dioxide, terpenes, vegetable oils and carbohydrates can be used a

293 that they could account for the majority of terpene volatiles produced in cv Royal Gala, including t

294 The highest total concentration of free terpenes was found at 19.3 degrees Brix; however, total

295 cal mechanism for the biosynthesis of cyclic terpenes, we anticipate that our work will enable the la

296 involved in the production of these volatile terpenes, we performed RNA sequencing to profile the tra

297 Total free and bound terpenes were more affected by grape density than by sam

298 Among thirty-one volatiles in guava powders, terpenes were predominant, even after both drying proces

299 rt a disparate synthetic approach to complex terpenes whereby simple prenyl-derived chains are cycliz

300 y lecithin phospholipids and Valencia orange terpenes, yet their addition significantly increased the