ライフサイエンスコーパス: testis cord

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1 tiate in the interstitium (the space between testis cords).

2 llular events leading to the organization of testis cords.

3 ted, leading to open and incompletely formed testis cords.

4 ular myoid cells and the formation of intact testis cords.

5 dent with expression of Sry and formation of testis cords.

6 ker of functional heterogeneity in mammalian testis cords.

7 1-expressing precursor cells located outside testis cords.

8 , we demonstrate that, although formation of testis cords and development of other cell types normall

9 on plays a critical role in the formation of testis cords and the differentiation of XY versus XX cel

10 ic testis, two compartments are defined: the testis cords and the interstitium.

11 LacZ-positive cells were exclusively outside testis cords and were 3betaHSD-negative, indicating that

12 However, by 13.5 dpc, the testis cords are disorganized and incompletely formed in

13 Germ cells are sequestered inside testis cords by 12.5 dpc where they arrest in mitosis.

14 and in the partitioning of interstitial and testis cord compartments.

15 votestes and B6 XY(AKR) fetuses have delayed testis cord development.

16 TGF-beta signaling, in Sertoli cells led to testis cord dysgenesis and proliferative defects similar

17 Leydig cells resulted in a failure of fetal testis cord elongation and expansion due to decreased Se

18 mpartmentalization leads to the formation of testis cords (epithelium) and the surrounding interstiti

19 ng the gonad into 10 avascular regions where testis cords form.

20 Although the process of testis cord formation is essential for male development,

21 Germ cell loss and abnormal testis cord formation were observed in both gain- and lo

22 , produce signaling molecules to orchestrate testis cord formation.

23 is important for male germ cell survival and testis cord formation.

24 The testis cords give rise to the adult seminiferous tubules

25 e 30 stage, corresponding to 12.5 dpc, after testis cords had formed and the basement membrane layer

26 that migrated into the gonad stayed outside testis cords, in the interstitium.

27 udies to date indicate that the formation of testis cords is critical for proper Sertoli cell differe

28 lar myoid cells, which normally surround the testis cords, is reduced.

29 rates initiation of vascular development and testis cord morphogenesis, and lead to a model in which

30 e embryo and are not known to be involved in testis cord morphogenesis.

31 essential role of fetal Leydig cells during testis cord morphogenesis.

32 terstitial cells also play critical roles in testis cord morphogenesis.

33 n, for the expression of Dmrt1 gene, and for testis cord morphogenesis.

34 The initiation of de novo testis cord organization in the fetal gonad is poorly un

35 rtoli cells, the epithelial cell type within testis cords, produce signaling molecules to orchestrate

36 a driving force in the de novo formation of testis cords, recent studies in mouse showed that reorga

37 cells are recombined with XY somatic cells, testis cord structures form normally; however, when XX g

38 l gonad undergo de novo organization to form testis cords that enclose germ cells inside tubules line

39 xpression and become Sertoli cells that form testis cords, whereas the remaining WT1(+) cells contrib

40 isruptive effect of Dhh(-/-) on formation of testis cords without influencing Sertoli cell differenti

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