ライフサイエンスコーパス: tetralogy of Fallot

1 in a concern in adult patients with repaired tetralogy of Fallot.

2 adoption of a RVOT-sparing strategy to treat tetralogy of Fallot.

3 ome, aortic stenosis, pulmonic stenosis, and tetralogy of Fallot.

4 e in risk stratifying patients with repaired tetralogy of Fallot.

5 f the human congenital cardiac defect termed tetralogy of Fallot.

6 nary RV dysfunction in adults after repaired tetralogy of Fallot.

7 t late sequelae for patients after repair of tetralogy of Fallot.

8 rst-degree AV block, idiopathic AV block, or tetralogy of Fallot.

9 mortality after transannular patch repair of tetralogy of Fallot.

10 with atrioventricular septal defect or with tetralogy of Fallot.

11 t, respectively, of patients after repair of tetralogy of Fallot.

12 rtant determinant of outcome after repair of tetralogy of Fallot.

13 aused congestive failure than in hearts with tetralogy of Fallot.

14 rmal heart as well as in surgically repaired tetralogy of Fallot.

15 with transposition of the great arteries and tetralogy of Fallot.

16 vere congenital heart defects in general, or tetralogy of Fallot.

17 ain some of the clinical variability seen in tetralogy of Fallot.

18 or secondary outcome parameters in repaired tetralogy of Fallot.

19 cular performance in patients with corrected tetralogy of Fallot.

20 g in children and young adults with repaired tetralogy of Fallot.

21 s with LCR22C-D deletions had CTDs including tetralogy of Fallot.

22 h clinical outcome in patients with repaired tetralogy of Fallot.

23 hmuses improves ablation outcome in repaired Tetralogy of Fallot.

24 ology are found among patients with repaired tetralogy of Fallot.

25 ansposition of the great arteries; and 8 for tetralogy of Fallot.

26 as the prudent class to have offspring with tetralogy of Fallot.

27 rtic root dilatation in adults with repaired tetralogy of Fallot.

28 ole exposure may confer an increased risk of tetralogy of Fallot.

29 minant FLT4 mutations accounting for 2.3% of Tetralogy of Fallot.

30 congenital heart defects such as in repaired tetralogy of Fallot.

31 ciated with smaller placental size at birth: tetralogy of Fallot, -0.45 (95% confidence interval, -0.

32 We found the following anomalies: tetralogy of Fallot (15 patients, 25%), tricuspid atresi

33 Most patients had tetralogy of Fallot (18/31).

34 The most common diagnoses were tetralogy of Fallot (19%) and hypertrophic cardiomyopath

35 dence of infective endocarditis was 1.3% for tetralogy of Fallot, 2.7% for isolated ventricular septa

36 patients (3%), including 9 of 201 (4%) with tetralogy of Fallot, 3 of 71 (4%) with a secundum ASD, o

37 ular septum, 7.8%; 2) paternal anesthesia in tetralogy of Fallot, 3.6%; 3) painting in atrioventricul

38 anian population (25%) or control cases with tetralogy of Fallot (30%).

39 Diagnoses included tetralogy of Fallot (51%), septal defects (20%), (congen

40 anomaly (40%), pulmonary atresia (11%), and tetralogy of Fallot (8%).

41 defect seems to be a single-gene defect and tetralogy of Fallot a polygenic disorder with a small nu

42 Fifty-seven patients with repaired tetralogy of Fallot (age >/=16 y; mean age, 35.8+/-10.1

43 ized controlled pilot study in patients with tetralogy of Fallot aged 10 to 25 years.

44 ralogy of Fallot with pulmonary atresia than tetralogy of Fallot alone.

45 der called Alagille syndrome, which includes tetralogy of Fallot among its more severe cardiac pathol

46 re not modified by supplement use except for tetralogy of Fallot; among supplement users, those in th

47 tion, transposition of the great arteries or tetralogy of Fallot, an event rate of 1/454 patients-yea

48 Eight patients with tetralogy of Fallot and 7 patients with transposition of

49 Of the 34 patients with tetralogy of Fallot and abnormal CA, 7 (21%) demonstrate

50 aorta and coronary artery anomalies, such as tetralogy of Fallot and double outlet right ventricle.

51 two common human congenital heart diseases, tetralogy of Fallot and double outlet right ventricle.

52 ount for a clinically significant portion of tetralogy of Fallot and idiopathic AV block.

53 ents who underwent surgical intervention for tetralogy of Fallot and major aortopulmonary collateral

54 nts with both native and previously operated tetralogy of Fallot and major aortopulmonary collateral

55 pulmonary collaterals (APCs) in infants with tetralogy of Fallot and pulmonary atresia (TOF/PA) and t

56 ath occurred in 12 of 25 patients (48%) with tetralogy of Fallot and pulmonary atresia, and 4 of 54 (

57 Adults with repaired tetralogy of Fallot and RV dysfunction (RV ejection frac

58 ients aged median 12.0 years after repair of tetralogy of Fallot and similar lesions were studied ech

59 so a subset of abnormalities associated with tetralogy of Fallot and the DiGeorge syndrome.

60 We detected associations for tetralogy of Fallot and the upper exposure categories fo

61 l assessment of PR in patients with repaired tetralogy of Fallot and warrants further investigation.

62 cts, 2 with patent ductus arteriosus, 2 with tetralogy of Fallot, and 1 with pulmonary valve dysplasi

63 efects, transposition of the great arteries, tetralogy of Fallot, and anomalous pulmonary venous retu

64 al septal defect, ventricular septal defect, tetralogy of Fallot, and transposition of the great arte

65 ations including ventricular septal defects, tetralogy of Fallot, and tricuspid atresia, defects that

66 ies, left-to-right shunts, valvular disease, tetralogy of Fallot, and truncus arteriosus.

67 and Fgf15 genes in mice are involved in the tetralogy of Fallot, and, using zebrafish phenotypes, pr

68 ; aortic stenosis; coarctation of the aorta; tetralogy of Fallot; and D-transposition of the great ar

69 opmental or neurological outcomes, including tetralogy of Fallot (AOR 2.4, 95% CI: 1.1, 5.4), anencep

70 defect (aOR = 1.19; 95% CI: 1.00, 1.43), and tetralogy of Fallot (aOR = 1.44; 95% CI: 1.01, 2.19) in

71 d incrementally 20 years after operation for tetralogy of Fallot, aortic stenosis and coarctation.

72 nd sudden cardiac death late after repair of tetralogy of Fallot are devastating complications in adu

73 r (RV) dysfunction in patients with repaired tetralogy of Fallot are incompletely understood.

74 Patients with repaired tetralogy of Fallot are monitored for pulmonary regurgit

75 beyond 30 years after surgical correction of tetralogy of Fallot are nonexistent.

76 Long-term outcomes of transatrial repair of tetralogy of Fallot are unknown.

77 transposition of the great arteries, and 81 tetralogy of Fallot, as well as their unaffected parents

78 of a patient with Abernethy malformation and tetralogy of Fallot associated with nodular regenerative

79 he outcomes of PVR in adults after repair of tetralogy of Fallot at a single tertiary center were ret

80 patients undergoing a transatrial repair of tetralogy of Fallot between 1980 and 2005 were reviewed,

81 In all patients after correction for tetralogy of Fallot, BNP levels were elevated and correl

82 w tract; group 2 (n = 22) received repair of tetralogy of Fallot by the traditional technique with ve

83 ricular septal defect, atrial septal defect, tetralogy of Fallot, coarctation of the aorta, cleft lip

84 55 years after diagnosis and first repair of Tetralogy of Fallot compared to natural progression.

85 with a cerebellar infarct and a history of a tetralogy of Fallot corrected during childhood.

86 aortic arch, aberrant subclavian artery and Tetralogy of Fallot, demonstrating that Hoxa1 is require

87 en with transposition of the great arteries, tetralogy of Fallot, double-chamber right ventricle, int

88 al septal defect, ventricular septal defect, tetralogy of Fallot, Ebstein anomaly, transposition of t

89 Patients with repaired tetralogy of Fallot experience variable outcomes for rea

90 of ventricular tachycardia (VT) in repaired Tetralogy of Fallot focuses on isthmuses in the right ve

91 cuspid valve abnormalities, five with severe tetralogy of Fallot, four with Ebstein's anomaly and two

92 t diameter < or =10 mm, diagnosis other than tetralogy of Fallot, Genesis stent, higher prestent RV:a

93 ute; P=0.01) and trended toward lower in the tetralogy of Fallot group (13.5+/-1.29 mL/kg per minute;

94 PVR after repair of tetralogy of Fallot has a low and improving mortality, w

95 ugh nearly one third of adults with repaired tetralogy of Fallot have an aortic root diameter >/=40 m

96 nary valve replacement (PVR) after repair of tetralogy of Fallot have recently been broadened to incl

97 In tetralogy of Fallot, heart defects occurred in seven (3.

98 CHD were studied (atrial septal defect in 6, tetralogy of Fallot in 4, and Fontan procedure in 6).

99 One patient died after surgery for tetralogy of Fallot in situs inversus.

100 Relative to sex-specific controls, repaired tetralogy of Fallot in women had larger right ventricula

101 AGS (e.g., peripheral pulmonic stenosis and tetralogy of Fallot) in the absence of liver dysfunction

102 FINE trial (Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-Angiotensin

103 Tetralogy of Fallot is a congenital heart disease that r

104 nary valve replacement (PVR) after repair of tetralogy of Fallot is commonly required and is burdenso

105 Clinical outcome after repair of tetralogy of Fallot is determined by the adaptation of t

106 dium, common atrioventricular canal, and the tetralogy of Fallot malformation.

107 btopics identified included heart failure in tetralogy of Fallot, mechanical circulatory support/tran

108 included ventricular septal defect (n = 11), tetralogy of Fallot (n = 3), atrioventricular canal (n =

109 sition of the great arteries (TGA) (n = 69), tetralogy of Fallot (n = 66), hypoplastic left heart syn

110 of the aorta/hypoplastic aortic arch (n=5), tetralogy of Fallot (n=1), hypoplastic right heart (n=1)

111 terial hypertension (PAH; n=10) and repaired tetralogy of Fallot (n=10) underwent MR-augmented cardio

112 syndrome (n=346), tricuspid atresia (n=103), tetralogy of Fallot (n=127), pulmonary atresia (n=177),

113 Patients with repaired tetralogy of Fallot (n=143; 12.5+/-3.2 years) had an ech

114 great arteries after Mustard/Senning (n=2), tetralogy of Fallot (n=2), aortic valve disease (n=2), a

115 The majority had a variant of tetralogy of Fallot (n=36), or transposition of the grea

116 ive associations between carbon monoxide and tetralogy of Fallot (odds ratio = 2.04, 95% confidence i

117 r "total correction." Patients with repaired tetralogy of Fallot often have pulmonary regurgitation,

118 entricular septal defect was associated with tetralogy of Fallot or double-outlet right ventricle in

119 dults (>/=18 years) with surgically repaired tetralogy of Fallot or pulmonary atresia with ventricula

120 Alagille syndrome and some cases of isolated tetralogy of Fallot or pulmonic stenosis.

121 rmal CA anatomy, especially in patients with tetralogy of Fallot or transposition of the great arteri

122 ncy and specific malformations that resemble tetralogy of Fallot, overriding aorta with ventricular s

123 in contrast to coarctation of the aorta and tetralogy of Fallot (P=0.002; Fisher exact test).

124 We included 413 tetralogy of Fallot patients (age, 36 +/- 13 years; QRS

125 Heart Disease (ACHD) centres that follow up Tetralogy of Fallot patients and Great Ormond Street Hos

126 surgical era, this physiology is present in tetralogy of Fallot patients at mid-term follow-up and w

127 Records from 28 consecutive repaired Tetralogy of Fallot patients from 2 centers who underwen

128 Both the PAH and tetralogy of Fallot patients had blunted exercise-induce

129 Although tetralogy of Fallot patients had the largest increase in

130 onductivity which, when defective, cause the tetralogy of Fallot phenotype.

131 replacement (PVR) in patients with repaired tetralogy of Fallot provides symptomatic benefit and rig

132 ose with pulmonary artery stenosis (n = 94), tetralogy of Fallot/pulmonary atresia (n = 72), congenit

133 In the first 24 hours after tetralogy of Fallot repair (n=11 patients), serial prosp

134 th adverse clinical outcomes in adults after tetralogy of Fallot repair (rTOF).

135 entricular (RV) dysfunction are common after tetralogy of Fallot repair (rTOF).

136 ren after total cavopulmonary connection and tetralogy of Fallot repair and may prove to be an import

137 1085 consecutive patients receiving standard tetralogy of Fallot repair in a single institution from

138 Thirteen patients, 3 to 35 years after tetralogy of Fallot repair or pulmonary valvotomy, had P

139 entricular (RV) restrictive physiology after tetralogy of Fallot repair results in low cardiac output

140 After tetralogy of Fallot repair, acute restrictive RV physiol

141 (SCD) complicate the long-term outcome after tetralogy of Fallot repair, yet the diagnostic and predi

142 obal RV function and exercise capacity after tetralogy of Fallot repair.

143 tients undergoing Fontan-type operations and tetralogy of Fallot repair.

144 ysiology can be present early and late after tetralogy of Fallot repair.

145 roportion of patients require PVR late after tetralogy of Fallot repair.

146 ry replicating a nontransannular approach to tetralogy of Fallot repair.

147 Most patients with repaired tetralogy of Fallot require pulmonary valve replacement

148 g atrial and ventricular septal defects, and tetralogy of Fallot, resembling some of the most common

149 After repair of tetralogy of Fallot, right ventricular (RV) dilation has

150 icular tachycardia (VT) late after repair of tetralogy of Fallot (rTOF).

151 In patients with tetralogy of Fallot, severe pulmonary stenosis and dimin

152 ally in patients with atrial septal defects, tetralogy of Fallot, single ventricle physiology, and fo

153 We performed a cross-sectional study of tetralogy of Fallot subjects who were tested for 22q11.2

154 erived standard deviation scores in repaired tetralogy of Fallot suggest that women perform poorer th

155 on complex congenital heart defects such as tetralogy of Fallot, systemic right ventricle, and unive

156 f CHDs, ventricular septal defect (VSD), and tetralogy of fallot (TF) with increasing O3 exposure.

157 the effect of PVR in patients with repaired tetralogy of Fallot that developed pulmonary insufficien

158 trant monomorphic ventricular tachycardia in tetralogy of Fallot, the anatomy and histology of these

159 athology has been described in patients with tetralogy of Fallot, the scope of the problem remains po

160 In patients with tetralogy of Fallot, the strongest correlations were obs

161 rom the mandatory follow-up of patients with Tetralogy of Fallot to model the health-related costs an

162 e contribute to cardiac defects ranging from tetralogy of Fallot to transposition of the great arteri

163 and central California carrying infants with tetralogy of Fallot (TOF) (n = 55), dextrotransposition

164 Adults late after total correction of tetralogy of Fallot (TOF) are at risk for major complica

165 termine if early primary repair of acyanotic tetralogy of Fallot (ToF) can be performed safely with l

166 Patients after repair of tetralogy of Fallot (ToF) frequently have right ventricu

167 ) for one-stage versus "two-stage" repair of tetralogy of Fallot (TOF) in infants younger than 1 year

168 ion-repolarization in patients with repaired tetralogy of Fallot (TOF) is a risk factor for malignant

169 Tetralogy of Fallot (TOF) is the commonest cyanotic form

170 Tetralogy of Fallot (TOF) is the most common cyanotic co

171 Tetralogy of Fallot (TOF) is the most common cyanotic co

172 Tetralogy of Fallot (ToF) is the most common form of com

173 le (RV) to adapt to hypoxia in children with tetralogy of Fallot (TOF) is unknown.

174 Individuals with tetralogy of Fallot (TOF) now routinely survive to repro

175 ion of the aortic root is a known feature in tetralogy of Fallot (TOF) patients with pulmonary stenos

176 ulmonary valve replacement (PVR) in repaired tetralogy of Fallot (TOF) reduces pulmonary regurgitatio

177 The timing of repair of tetralogy of Fallot (TOF) remains controversial.

178 mpaired clinical status in late survivors of tetralogy of Fallot (TOF) repair.

179 Tetralogy of Fallot (TOF) typically results in clinical

180 Diagnoses included tetralogy of Fallot (TOF) with pulmonary atresia (n=13),

181 myocardium from 16 infants with nonsyndromic tetralogy of Fallot (TOF) without a 22q11.2 deletion, 3

182 amined the 1q21.1 locus in 948 patients with tetralogy of Fallot (TOF), 1488 patients with other form

183 atrial appendage, ventricular septal defect, tetralogy of Fallot (TOF), and an aortic arch abnormalit

184 heart disease and 36% (n=326) of these have tetralogy of Fallot (TOF), comprising the largest subset

185 Disease entities included were tetralogy of Fallot (TOF), double outlet right ventricle

186 excess familial recurrence of non-syndromic Tetralogy of Fallot (TOF), implicating genetic factors t

187 Tetralogy of Fallot (TOF), the most common severe congen

188 y to search for risk alleles associated with Tetralogy of Fallot (TOF), using a northern European dis

189 ison with a cohort of patients with repaired tetralogy of Fallot (TOF).

190 mortality remain problematic after repair of tetralogy of Fallot (TOF).

191 etermine pregnancy outcomes in patients with tetralogy of Fallot (TOF).

192 vastating late complications after repair of Tetralogy of Fallot (ToF).

193 t ventricular outflow tract of postoperative tetralogy of Fallot (TOF).

194 he transcription factor NKX2.5 as a cause of tetralogy of Fallot (TOF).

195 a large group of preoperative patients with tetralogy of Fallot (TOF).

196 truction in patients after primary repair of tetralogy of Fallot (TOF).

197 with truncus arteriosus (TA), and 15.9% with tetralogy of Fallot (TOF).

198 uctus arteriosus, valvar pulmonary stenosis, tetralogy of Fallot, transposition of the great arteries

199 congenital cardiovascular disease, including tetralogy of Fallot, truncus arteriosus and interruption

200 Severe CHD was defined as tetralogy of Fallot, truncus arteriosus, transposition c

201 icenter cohort of 252 patients with repaired tetralogy of Fallot undergoing programmed ventricular st

202 was performed on 205 patients with repaired tetralogy of Fallot undergoing PVR at our institution be

203 Patients with repaired tetralogy of Fallot undergoing PVR with history of ventr

204 3.3 years [range, 8-20 years]) with repaired tetralogy of Fallot underwent cardiac magnetic resonance

205 n age 22+/-11 years; range, 8.5 to 64.9; 72% tetralogy of Fallot) underwent PVR for severe pulmonary

206 g long-term follow-up, transatrial repair of tetralogy of Fallot was associated with a minimal risk o

207 A significantly increased risk of tetralogy of Fallot was observed (7 cases in fluconazole

208 The average cost per patient of a repair for Tetralogy of Fallot was pound26,938 (SE = pound4,140).

209 Tetralogy of Fallot was present in 23 subjects and was a

210 he study population was 21.5+/-11 years, and tetralogy of Fallot was the cardiac condition in 59%.

211 a from 62 consecutive patients with repaired tetralogy of Fallot were analyzed (median age at follow-

212 pulmonary regurgitation following repair of tetralogy of Fallot were considered benign.

213 Autopsy hearts with tetralogy of Fallot were evaluated to clarify the pathol

214 Twenty-seven hearts with the diagnosis of tetralogy of Fallot were examined.

215 Infants with tetralogy of Fallot were smaller in all measured dimensi

216 Her prior history was significant for tetralogy of Fallot which was repaired at nine months of

217 replacement (PVR) in patients with repaired tetralogy of Fallot who develop pulmonary insufficiency

218 hort study consists of the 144 patients with tetralogy of Fallot who underwent surgical repair at <15

219 vere form of the human birth defect syndrome tetralogy of Fallot with complete pulmonary artery atres

220 Four groups of tetralogy of Fallot with confluent central pulmonary art

221 Tetralogy of Fallot with cyanosis requiring surgical rep

222 Tetralogy of Fallot with diminutive pulmonary arteries a

223 a novel transcatheter management approach in tetralogy of Fallot with diminutive pulmonary arteries.

224 Tetralogy of Fallot with major aortopulmonary collateral

225 icular outflow tract stenting of symptomatic tetralogy of Fallot with poor anatomy (small pulmonary a

226 child with Alagille syndrome suffering from tetralogy of Fallot with pulmonary atresia and multiple

227 VCF) dysmorphic features, and more common in tetralogy of Fallot with pulmonary atresia than tetralog

228 ere pulmonary stenosis is rare and resembles tetralogy of Fallot with pulmonary atresia: There is a h

229 initially described as a phenotypic mimic of Tetralogy of Fallot with pulmonary atresia; however, sub

230 groups: group 1 (n = 20) received repair of tetralogy of Fallot with the modified technique with tra

231 these patients had undergone total repair of tetralogy of Fallot within 2 wks after admission for RSV