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1 ere fusions and most were tetraploid or near-tetraploid.
2 ted with macrozoospermia and these sperm are tetraploid.
3 nce transcriptome asymmetry in the synthetic tetraploid.
4 resulting in the formation of stable a/alpha tetraploids.
5 rine epithelial cells promotes generation of tetraploids.
6 ewly formed hybrids or to diploidizing (auto)tetraploids.
7 tion genetics and hence breeding programs of tetraploids.
8 tributed to the initial establishment of the tetraploids.
9 (2n=2x=30; O. spinosa and O. intermedia) and tetraploid (2n=4x=60; O. repens and O. maritima) taxa ex
11 loidy series consisting of the diploid (2X), tetraploid (4X) and hexaploid (6X) lines and compared th
13 versely, the defects of hybrid seeds between tetraploid A. arenosa and diploid A. lyrata were aggrava
14 to form viable hybrid seeds with diploid and tetraploid A. arenosa, associated with the reestablishme
17 er (Triticum turgidum ssp. dicoccoides), the tetraploid AB-genome progenitor of domesticated wheat ha
18 the other isolates that were collected from tetraploid (AB genomes) durum wheat and hexaploid (ABD g
23 yping applications, SNPs polymorphic between tetraploid and diploid species were included for use in
25 lic characteristics were studied in diploid, tetraploid and hexaploid cytotypes of Atriplex canescens
26 reached highest levels at the last stage of tetraploid and hexaploid grain development, suggesting t
28 d, on average, 2,705 and 5,351 mutations per tetraploid and hexaploid line, respectively, which resul
29 vegetative tissues and developing grains of tetraploid and hexaploid wheat, suggesting their functio
32 yocytes with 2n diploid DNA content and that tetraploid and octaploid nuclei constitute only a small
33 ypes: a northern upland ecotype, composed of tetraploid and octoploid accessions, and a southern lowl
36 a, exemplifying the long-term persistence of tetraploids and the multiple origins of hexaploids relat
38 o the relationships between various Brassica tetraploids and their diploid-progenitors at a single-ba
39 metastases are generally aneuploid, but not tetraploid, and are histopathologically similar to the p
41 ene loss between the genomes of this ancient tetraploid, and perhaps all tetraploids, is the result o
42 rtex and chick telencephalic derivatives are tetraploid, and that in the mouse ~85% of these neurons
43 groups: (i) putative diploids, (ii) putative tetraploids, and (iii) the hybrid cultivated species S.
45 enotypes containing diploids, triploids, and tetraploids, and the Chilotanum Group of lowland tetrapl
46 r order polyploids than between diploids and tetraploids, and unreduced gametes may facilitate diploi
47 ated genome elimination to convert a natural tetraploid Arabidopsis into a diploid, reducing its ploi
49 e competing pathways modulate DNTF, and that tetraploid Arabidopsis will be a powerful model for eluc
50 signaling or defective autophagy or that are tetraploid are eliminated at the onset of differentiatio
52 st frequently wild type in melanoma, and the tetraploid arrest and down-regulation of G2/M regulatory
55 n, as siRNA suppression of p16INK4a bypasses tetraploid arrest, permitting primary cells to become an
56 and fetuses of tetraploid ESC chimeras were tetraploid as determined by fluorescence activated cell
57 Comparison of genomic sequences from several tetraploid (AtDt) Gossypium species and genotypes with p
60 s (BBAA) and ssp. durum (BBAA), an extracted tetraploid (BBAA), and a synthetic tetraploid (S(l) S(l)
62 e ES cell with such increased potency into a tetraploid blastocyst gives rise to an entire embryo wit
64 s between a wart resistant and a susceptible tetraploid breeding clone was evaluated for resistance t
65 cally viewed as bridges between diploids and tetraploids but rarely as parental genomes of high-level
68 ic hyperaccumulating fern Pteris vittata and tetraploid 'C-fern Express' (Ceratopteris thalictroides)
74 hybridization performed on DNA derived from tetraploid cell-induced tumors indicates amplifications
75 s termed "mitotic slippage," which generates tetraploid cells and limits the effectiveness of antimit
76 gene expression evoked in acute and adapted tetraploid cells and their effect on cell-cycle progress
81 gent that selectively reduces the fitness of tetraploid cells by slowing down their cell cycle progre
92 on restoration of telomere protection, these tetraploid cells resumed cell division cycles and prolif
94 Failed cytokinesis in humans can result in tetraploid cells that can become aneuploid and promote c
104 aploids, and the Chilotanum Group of lowland tetraploid Chilean landraces); (ii) S. ajanhuiri (diploi
106 procedures necessary to produce specialized tetraploid chimeras using tetraploid morula<-->diploid E
110 ion analysis of single cell-derived, adapted tetraploid clones showed up-regulation of several p53 ta
111 ated from Nutlin-3a treated cells, and these tetraploid clones were more resistant to ionizing radiat
112 ncy by generating full-term or adult mice in tetraploid complementation assays, raising questions as
113 ort the development of "all-iPS" animals via tetraploid complementation, the most stringent test avai
117 ified: quadruplets retaining their ancestral tetraploid condition, semi-quadruplets still reflecting
120 iber genes with a biased distribution in the tetraploid cotton (Gossypium hirsutum L.) genome that wa
121 ributes to the superior yield and quality of tetraploid cotton fibers may be explained by accelerated
123 omology between the diploid D genome and the tetraploid cotton genetic map, with only a few minor pos
125 singleton SNPs of known genomic location in tetraploid cotton provided unique opportunities to chara
127 that subokra is the ancestral leaf shape of tetraploid cotton that gave rise to the okra allele and
135 the higher fibre productivity and quality of tetraploid cottons than diploid cottons bred for the sam
137 ced pentaploids exclusively, whereas diploid-tetraploid crosses produced both triploids and tetraploi
138 in tetraploid-hexaploid crosses than diploid-tetraploid crosses, mostly due to substantially higher g
139 G. hirsutum A(t)D(t) (in which 't' indicates tetraploid) cultivar reveals many non-reciprocal DNA exc
140 o SATlotyper on an experimentally haplotyped tetraploid dataset of 12 SNPs, and show that polyHap is
141 of chick retinal projection neurons becomes tetraploid during development, an event prevented by blo
142 of recombinant inbred lines derived from the tetraploid durum wheat variety Langdon crossed with a La
143 cental development and the rescue of IUGR by tetraploid embryo complementation did not restore beta c
144 a-embryonic deficiency is circumvented using tetraploid embryo complementation, cardiac myocyte diffe
145 capacities of chimeras created by injecting tetraploid embryonic stem cells (ESCs) expressing green
146 in the extraembryonic tissues and fetuses of tetraploid ESC chimeras were tetraploid as determined by
151 on and abnormal differentiation potential of tetraploid ESCs might be two of the reasons for their po
152 We further found that the proliferation of tetraploid ESCs was slower than that of diploid ESCs.
153 3.5 days post-coitum (dpc) and 4.5 dpc, the tetraploid ESCs were able to contribute to the inner cel
154 cross (pollinating a diploid "mother" with a tetraploid "father") but repressed in the reciprocal cro
158 In the present study, Nutlin-3a promoted a tetraploid G(1) arrest in multiple p53 wild-type cell li
159 In our previous study, Nutlin-3a promoted a tetraploid G(1) arrest in two p53 wild-type cell lines (
160 e present in both the A- and D-subgenomes in tetraploid G. hirsutum, and increased in abundance in bo
161 man foreskin fibroblasts become senescent in tetraploid G1 after drug- or small interfering RNA (siRN
162 iRNA-mediated knockdown of p21 abrogated the tetraploid G1 arrest and induced killing that was depend
163 hat can be targeted by UCN-01, and second, a tetraploid G1 arrest that can be targeted by siRNA again
164 ter time points, 4N arrested cells assumed a tetraploid G1 state that was characterized by depletion
165 ds--first-generation mutants screened from a tetraploid genetic background--reveal that a 70% fitness
166 referential pairing and the structure of the tetraploid genome and as a step toward identification of
167 to create artificial diploid, triploid, and tetraploid genotypes, and use these to demonstrate that
171 zygotic isolation was significantly lower in tetraploid-hexaploid crosses than diploid-tetraploid cro
174 delete mouse chromosomes 9, 10, 12, or 14 in tetraploid immortalized murine embryonic fibroblasts.
177 ed, including 9 diploids, 13 triploids and 7 tetraploids, in the Active Germplasm Bank, at Embrapa Ca
179 igenesis in that aneuploidy arises through a tetraploid intermediate and subsequent unequal DNA segre
180 ze its xylose-utilization phenotype, using a tetraploid intermediate, followed by bulk segregant anal
181 of salicylate, repressed the accumulation of tetraploid intestinal epithelial cells in the Apc(Min/+)
182 53, which causes unrestrained propagation of tetraploids into aneuploid cells, further undermines gen
183 modelling suggests that rapid adaptation of tetraploids is driven by higher rates of beneficial muta
184 of this ancient tetraploid, and perhaps all tetraploids, is the result of selection against loss of
185 han ploidy status with multidrug resistance, tetraploid isogenic cells that had arisen from diploid c
186 reads from a GBS library of 48 accessions of tetraploid kiwiberry (Actinidia arguta), GBS-SNP-CROP yi
188 maintained chromosome numbers at or near the tetraploid level, and the loss and gain of chromosomes f
189 ber-producing diploid ancestor contribute to tetraploid lint fiber genetics gain further support from
190 of eight switchgrass genotypes representing tetraploid lowland and octoploid upland cultivars to ben
193 n developed for either disomic or tetrasomic tetraploids may not be generally applicable, particularl
194 addition, SMT2 allelic mutants also generate tetraploid meiocytes through the ectopic induction of pr
195 alled enlarged tetrad2 (et2), which produces tetraploid meiocytes through the stochastic occurrence o
196 isation between diploid Mimulus guttatus and tetraploid Mimulus luteus, two species that were introdu
198 (bh(t)) locus regulating spike branching in tetraploid 'Miracle-Wheat.' Both genes possess orthologs
201 the phenotype, we first generated wild-type tetraploid/mutant diploid aggregates that should lead to
202 approximately 5.89 Ma, while the Australian tetraploid N. billardieri, is an independently derived,
203 nge projection neurons as well since ~80% of tetraploid neurons in this structure express calbindin,
204 of both NeuN and CTIP2-positive neocortical tetraploid neurons, thus providing genetic evidence for
205 upport previous taxonomic arguments that the tetraploid O. punctata might be better treated as a sepa
206 ichingeri (C-genome) were the progenitors of tetraploid O. punctata with O. punctata being the patern
207 differentiation between natural diploids and tetraploids of Arabidopsis arenosa, an outcrossing relat
208 ritance of microsatellite markers in natural tetraploids of Rorippa amphibia and R. sylvestris is tet
211 analysis of MSCs revealed the development of tetraploid or aneuploid karyotypes in the rhesus cells a
213 trol and salicylate reduced the formation of tetraploid or higher-order polyploid cells resulting fro
216 for engineering lignin biosynthesis in this tetraploid outcrossing species is not straightforward.
219 size that following a chaotic wide-cross/new tetraploid period, genes acquire their new expression ba
220 Achillea borealis (Asteraceae), a widespread tetraploid plant with localized hexaploid populations.
221 osses between triploid and either diploid or tetraploid plants and karyotyped all surviving individua
224 bone marrow cells were reprogrammed into new tetraploid pluripotent stem cells that successfully diff
225 nd two hexaploid populations each crossed to tetraploid populations spanning the geographic and phylo
226 ing sequence, the heterogenous nature of the tetraploid potato genome contributes to a highly dynamic
228 s in the diversification of long-day-adapted tetraploid potatoes, showing that extant natural populat
229 loid karyotype are thought to originate from tetraploid precursors, but the cause of tetraploidizatio
232 he production of haploid spermatids from the tetraploid primary spermatocytes via meiotic cell divisi
234 uires knowledge about the genome of its allo-tetraploid progenitor, wild emmer (T. turgidum ssp.
236 nt chromosome numbers, including diploid and tetraploid progeny, as well as a swarm of aneuploid prog
239 ng reproductive barriers between diploid and tetraploid Restharrows in Britain, but not within ploidy
242 extracted tetraploid (BBAA), and a synthetic tetraploid (S(l) S(l) AA) wheat together with its diploi
243 s show that all of the compounds that induce tetraploid senescence inhibit Aurora kinase B (AURKB).
244 s that our protocol is capable of amplifying tetraploid senescence, which can be observed in only a s
246 hybridization and sequence analysis in five tetraploid species and their ancestral A and D genome di
247 of four self-sustaining clonal lineages of a tetraploid species resulting from fertilization of tripl
248 d chloroplast fragments from all diploid and tetraploid species with the B- and C-genome types in thi
249 ong support for recent hybrid origins of the tetraploid species within the past 100,000-300,000 y fro
256 are similar structural features in different tetraploid species; yet, lncRNAs slightly differ from co
257 here is accumulating evidence of a transient tetraploid state proceeding to aneuploidy in cancer prog
262 rowth defect of both bub1Delta and sgo1Delta tetraploids, suggesting that these mutants die due to de
264 sequence tags (ESTs) were generated from two tetraploid switchgrass genotypes, Alamo AP13 and Summer
265 us comparisons between diploid and (usually) tetraploid taxa, we know very little about how elevated
267 on, suggesting that some carcinomas begin as tetraploid then descend into diploidy accompanied by gen
268 Most of the commercially-grown cotton is tetraploid, thus making it much more difficult to target
269 forward mutagenesis screens, scaling down a tetraploid to lower ploidy levels and swapping of nuclea
270 candidate disease resistance genes, to guide tetraploid transcript assemblies and to detect genetic e
272 ot been described so far in polyploid wheat (tetraploid Triticum turgidum and hexaploid Triticum aest
277 ocus in a collection of mutant and wild-type tetraploid wheat accessions revealed that a single amino
278 these methods to six independent M2 lines of tetraploid wheat demonstrated that our bioinformatics pi
279 a significant overestimate of the time since tetraploid wheat formation, which occurred no more than
280 Additionally, several wild relatives of tetraploid wheat have already shown a significant drough
283 egion were analysed in 104 accessions of six tetraploid wheat species (Triticum dicoccoides, T. dicoc
284 We sequenced root transcriptome of three tetraploid wheat varieties with varying stress tolerance
286 s of hexaploid wheat, the A and B genomes of tetraploid wheat, and the A, S, and D genomes of the dip
287 abase assembly of the 14 chromosomes of wild tetraploid wheat, as well as analyses of gene content, g
288 tic and physical maps of glaucous and glossy tetraploid wheat, demonstrating entirely different haplo
291 bution of chloroplast haplotypes of the wild tetraploid wheats and A. speltoides illustrates the poss
292 ssing patterns between synthetic and natural tetraploid wheats, it appears that the shock-induced exp
293 oung inflorescences in wild and domesticated tetraploid wheats, Triticum turgidum ssp. dicoccoides (B
294 og expression apparently occurred in natural tetraploid wheats, which led to novel transcriptome asym
296 yped region of chromosome from triploids and tetraploids, while for diploids we found polyHap to be m
298 n Capsella bursa-pastoris, a recently formed tetraploid with one of the most widespread species distr
299 is in two highly related species, the pseudo-tetraploid Xenopus laevis and diploid Xenopus tropicalis
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