ライフサイエンスコーパス: tetraploidization

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1 rmalities, including cytokinesis failure and tetraploidization.

2 n deteriorates cellular fitness by enhancing tetraploidization.

3 more likely reason for furrow regression and tetraploidization.

4 a large number of duplicated genes following tetraploidization.

5 at the additional X. laevis genes arose from tetraploidization.

6 s, and the other that coincided with Xenopus tetraploidization.

7 es may have undergone an additional round of tetraploidization.

8 ocument the role of p53 and Rb in repressing tetraploidization.

9 e screen, and identified mechanisms by which tetraploidization affects genomic stability.

10 Tetraploidization, along with large internal duplication

11 Furthermore, polyploidization of wheat (both tetraploidization and hexaploidization) induced revoluti

12 ized by centrosome amplification, chromosome tetraploidization and premature sister chromatid segrega

13 ecent studies implicating telomere-dependent tetraploidization as an important mechanism in carcinoge

14 understood but probably include prior genome tetraploidization, centrosome amplification and mitotic

15 elomere damage, we show that telomere-driven tetraploidization enhances the tumorigenic transformatio

16 olved independently since the soybean genome tetraploidization event approximately 13 million years a

17 ding to these results, we hypothesize that a tetraploidization event in A. lyrata allowed the product

18 egmental and tandem duplications following a tetraploidization event.

19 al support for the idea of an ancient genome tetraploidization event.

20 nce for an ancient whole-genome duplication (tetraploidization) event that probably occurred just bef

21 Although the ancestor of maize arose by tetraploidization, fewer than half of the genes appear t

22 at an increase in proliferative activity and tetraploidization had occurred already in mildly dysplas

23 Tetraploidization has been proposed as an intermediate s

24 est a general mechanism for the induction of tetraploidization in the early stages of tumorigenesis w

25 n maize arose as a consequence of an ancient tetraploidization in the maize ancestral lineage.

26 These data establish that telomere-driven tetraploidization is induced by critically short telomer

27 from tetraploid precursors, but the cause of tetraploidization is unknown.

28 version event detected for one of the genes, tetraploidization must have occurred before 4.8 Mya, and

29 We report that tetraploidization occurs in p53-deficient cells experien

30 Moreover, artificial tetraploidization of diploid cancer cells led to a reduc

31 ies in maize has probably occurred since the tetraploidization of maize, and may contribute to flower

32 ralogous genes that arose as a result of the tetraploidization of the maize genome.

33 Tetraploidization, or genome doubling, is a prominent ev

34 and moderate dysplasias, indicating that the tetraploidization precedes the loss or gain of specific

35 cells have an increased rate of spontaneous tetraploidization, suggesting that apoptosis may play an

36 to study whether p75(NTR)-dependent neuronal tetraploidization takes place in the cerebral cortex, gi

37 aneuploid, although a slight tendency toward tetraploidization was observed.

38 To investigate the fate of its genes after tetraploidization, we analyzed the sequence of five dupl

39 t of the chromosome rearrangements following tetraploidization were centric fusions and did not invol

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