ライフサイエンスコーパス: thalamostriatal

1 atory synaptic circuits, corticostriatal and thalamostriatal.

2 We conclude that the main excitatory thalamostriatal afferents differ in many of their charac

3 n microscopic analysis of the synaptology of thalamostriatal afferents to the matrix compartments fro

4 lar glutamate transporter type 2 (VGluT2) by thalamostriatal afferents.

5 ow from the patch and matrix compartments by thalamostriatal afferents.

6 imary brain developmental disorder affecting thalamostriatal and callosal pathways, also present in t

7 time window for synaptic integration between thalamostriatal and corticostriatal inputs, which might

8 cate that DCS is a region of convergence for thalamostriatal and corticostriatal projections from reg

9 ostriatal) and vGluT2-positive (i.e., mostly thalamostriatal) axo-spinous glutamatergic synapses usin

10 We have previously found that thalamostriatal axodendritic terminals are reduced as ea

11 rging with glutamatergic corticostriatal and thalamostriatal axon terminals at dendritic spines of me

12 onnectivity, it was found that activation of thalamostriatal axons in a way that mimicked the respons

13 h the DYT1 dystonia mutation, stimulation of thalamostriatal axons, mimicking a response to salient e

14 resynaptic mGluR1a labeling of glutamatergic thalamostriatal boutons and, less frequently, dopaminerg

15 The dynamics of thalamostriatal, but not corticostriatal, synapses were

16 r SAPAP family member, SAPAP4, is present at thalamostriatal, but not corticostriatal, synapses.

17 ptic transmission in the corticostriatal and thalamostriatal circuits of Sapap3 KO mice and littermat

18 lice preparation that preserved cortico- and thalamostriatal connectivity, it was found that activati

19 is rewiring involves corticostriatal but not thalamostriatal contacts onto MSNs.

20 indings demonstrate that corticostriatal and thalamostriatal glutamatergic axo-spinous synapses displ

21 erential pattern of synaptic organization of thalamostriatal glutamatergic inputs to the patch and ma

22 Thalamostriatal input, dopaminergic input, as well as in

23 is reproduced by activating ChR2-expressing thalamostriatal inputs, which synchronize cholinergic in

24 i/SNr to determine the relationships between thalamostriatal neurons and basal ganglia afferents.

25 avoidance learning, directly implicating the thalamostriatal pathway in reward-based learning.

26 excitatory synapses from corticostriatal and thalamostriatal pathways and their postsynaptic targets

27 racterize the role(s) of corticostriatal and thalamostriatal pathways in regulating basal ganglia act

28 These data suggest that the loss of thalamostriatal PF neurons in Parkinson's Disease is a p

29 As the thalamostriatal projection is heterogeneous, we set out

30 a3e (encoding Sema3E) is highly expressed in thalamostriatal projection neurons, whereas in the stria

31 plasticity suggest that corticostriatal and thalamostriatal projection systems code information in t

32 and functional specificity of basal ganglia-thalamostriatal projections and discusses various aspect

33 atal afferents but strikingly different from thalamostriatal projections arising from the parafascicu

34 Additional thalamostriatal projections arose from VA, VL pars cauda

35 We used anterograde axonal tracing to map thalamostriatal projections from LP and surrounding thal

36 It also discusses the importance of thalamostriatal projections from the caudal intralaminar

37 In primates, thalamostriatal projections from the centromedian (CM) a

38 This study examines the organization of thalamostriatal projections from ventral tier nuclei tha

39 Although the existence of thalamostriatal projections has long been known, the rol

40 These results implicate thalamostriatal projections in the pathophysiology of PD

41 cortex and raise the possibility that VA/VL thalamostriatal projections neurons have divergent conne

42 VA/VL thalamostriatal projections terminate in broad, rostroca

43 Corticostriatal and thalamostriatal projections utilize glutamate as their n

44 nd vGluT2, as markers of corticostriatal and thalamostriatal projections, respectively, we demonstrat

45 Although previous thalamostriatal studies emphasize projections from the i

46 We found that thalamostriatal synapses differ significantly in their p

47 ittle is known about how corticostriatal and thalamostriatal synapses differ.

48 n functional and anatomical rearrangement of thalamostriatal synapses specifically in direct-pathway

49 SAPAP isoforms at corticostriatal and thalamostriatal synapses were detected using immunostain

50 In contrast, at thalamostriatal synapses, a single afferent volley decre

51 In contrast to corticostriatal synapses, thalamostriatal synaptic activity is unaffected by Sapap

52 ess the possibility that degeneration of the thalamostriatal system could underlie some of the defici

53 siological data that support the role of the thalamostriatal system in action selection, attentional

54 anding of the neural mechanisms by which the thalamostriatal system integrates and regulates the basa

55 high degree of functional specificity of the thalamostriatal system through which CM/Pf may provide a

56 e the pathophysiology of corticostriatal and thalamostriatal systems in PD.

57 cleus indicate that both corticostriatal and thalamostriatal terminals express presynaptic GluR6/7 an

58 o chemogenetic and optogenetic inhibition of thalamostriatal terminals reversed motor deficits in dop