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2 s comprised of a variety of cancer diatheses that manifest a spectrum of distinct biologic potentials
5 al nocturnal hemoglobinuria (PNH), a disease that manifests after clonal expansion of hematopoietic c
6 lting in chronically deactivated macrophages that manifest an impaired ability to control pathogens.
7 e show (i) there is a set of 255 transcripts that manifest an increase in translational efficiency du
9 with a CD8 T-cell IL-15-transgenic leukemia that manifests an autocrine IL-15/IL-15Ralpha pathway pr
11 have produced the first novobiocin analogues that manifest anti-proliferative activity against severa
13 be diketo acid inhibitors of HIV-1 integrase that manifest antiviral activity as a consequence of the
14 ports suggest that animals produced with ART that manifest apparent epigenetic defects typically do n
15 it a delayed onset of neurologic dysfunction that manifests around the child's first birthday and pro
18 axias are autosomal dominant channelopathies that manifest as attacks of imbalance and incoordination
19 rs result in tissue-level control mechanisms that manifest as biological oscillators, such as observe
20 s as well as cause direct pathologic effects that manifest as clinical disease such as HIV-associated
23 se LBNP, disrupt MSNA firing characteristics that manifest as fused integrated bursts before the onse
24 currently being used to investigate diseases that manifest as global disturbances of brain function.
25 es can have nontargeted heterologous effects that manifest as increased protection against nonvaccine
26 a group of fatal neurodegenerative disorders that manifest as infectious, sporadic, or familial and a
27 aging for diagnosis of malignancy in lesions that manifest as microcalcifications at mammography.
28 This lends further support that lung cancers that manifest as NSNs have an indolent course and can be
31 acterized by unwanted, repetitive behaviours that manifest as stereotyped movements and vocalizations
33 enes causes neurodevelopmental abnormalities that manifest as the fractionation of mental abilities t
34 development, disruptions in motor behaviors that manifest as unproductive swim attempts, and spontan
35 to be effective for treating variant angina that manifested as a non-respiratory tract symptom of as
36 n of the pancreas by gut-derived lymphocytes that manifested as a pancreatic insulitis with beta-isle
37 formed consent was obtained, 50 lung cancers that manifested as a solid nodule on computed tomographi
38 +)) mice showed developmental irregularities that manifested as adult-onset glomerulosclerosis and pr
39 treatment generated oxidative genome damage that manifested as an accumulation of oxidized bases in
40 of LASY aggravated the inflammatory response that manifested as an increase in both basal and TNF-alp
41 ependence of release after block of activity that manifested as an increase in probability of release
42 nic mice correlated with an atopic phenotype that manifested as blepharitis and pulmonary inflammatio
43 S. aureus conferred responsiveness to IL-20 that manifested as modification of actin polymerization
44 e, GAT1 and SGLT1 exhibited charge movements that manifested as pre-steady-state current transients.
45 2 months, had significant cutaneous disease that manifested as red violaceous plaques of the cheeks,
46 arly increase in vesicular glutamate release that manifests as a fourfold increase in the frequency o
48 rdium is shown to provide a voltage gradient that manifests as a J (Osborn) wave or elevated J-point
49 ectra were represented in Kubelka-Munk units that manifests as a linear dependence of spectral peak h
50 ase type II, is a lysosomal storage disorder that manifests as a progressive myopathy, secondary to m
51 ous defect in hematopoietic progenitor cells that manifests as abnormal myeloid and B-lymphoid develo
52 d to the genetic liability for schizophrenia that manifests as altered reconfiguration of brain netwo
53 a substrain (B10.Q-H2-(q)/SgJ) of B10.Q mice that manifests as an acute susceptibility to infection b
54 PFC functional connectivity in schizophrenia that manifests as an unmodulated persistence of an HF-DL
55 ant role in progression to chronic rejection that manifests as bronchiolitis obliterans syndrome (BOS
56 idence of optic nerve or retinal dysfunction that manifests as decreased contrast sensitivity, even w
57 ndent latent modulation of GABA(A)R function that manifests as delayed-onset uncoupling may be releva
58 due to an excess of neural progenitor cells that manifests as early as embryonic day 9.5 in developm
60 en characterized by a robust B-cell response that manifests as increased intrathecal immunoglobulin G
61 il to detect or else conflate generalization that manifests as increased learning rate with generaliz
62 syndrome (WAS) is a primary immunodeficiency that manifests as increased susceptibility to many patho
63 versely, breakdown of medial immunoprivilege that manifests as more intense leukocytic infiltrates, l
64 ome should be redefined as one of starvation that manifests as obesity in a food-rich environment.
65 eloma is a malignant disease of plasma cells that manifests as one or more of lytic bone lesions, mon
66 nes may represent a rudimentary relationship that manifests as out-of-phase oscillation of Fgf and Wn
67 xample, the AhR regulates PAH immunotoxicity that manifests as pre-B cell apoptosis in models of B ce
68 a (PHN) is a common complication of shingles that manifests as prolonged excruciating pain, which has
69 siological evidence of "hidden hearing loss" that manifests as reduced neural output from the cochlea
70 ed focal dystonia is a neurological disorder that manifests as repetitive involuntary spasms and/or a
71 ome is an inherited and irreversible disease that manifests as retinitis pigmentosa (RP) and bilatera
72 that appeared in a colony of FVB/N mice and that manifests as severe ataxia appearing at around 12 d
73 rare hereditary disease of heme biosynthesis that manifests as severe photosensitivity and hepatotoxi
76 tory condition of the gastrointestinal tract that manifests as ulcerative colitis and Crohn disease.
80 Our data highlight a complexity to binding that manifests at higher temperatures and can be explain
84 ptide-MHC-II molecules become effector cells that manifest better recall responses, and Tregs with ca
85 le increases in CBF throughout the forebrain that manifested bilaterally, albeit with an ipsilateral
87 en fluorescent protein tagged to 37 alanines that manifests both toxicity and inclusion formation in
88 rophage responses in a dose-dependent manner that manifested by an increased TNF-alpha and IL-12, but
89 somatic expression of CaV2.1 splice variants that manifest CDF and progressive dendritic targeting of
90 r array of isotopologs along the fibril axis that manifests clearly identifiable vibrational transiti
91 trinsic mechanism for human vascular disease that manifests clinical complications in sickle cell dis
92 endent roles in the complex immune responses that manifest clinically as asthma and other allergic di
93 terorgan and intraorgan vessel heterogeneity that manifest clinically in a disparate response of diff
94 and leads to mucosal damage and inflammation that manifests clinically as antibiotic-associated diarr
95 liferation and loss of functional liver mass that manifests clinically as ascites, encephalopathy, an
97 antigen load drives an inflammatory response that manifests clinically as TBM-IRIS in most, but not a
98 lly affected by the type I collagen mutation that manifests clinically in their heterozygous offsprin
99 ptured prevalent mixed-lineage intermediates that manifested concurrent expression of haematopoietic
100 genital, autosomal recessive retinal disease that manifests cone dysfunction, reduced visual acuity a
103 gene are associated with cornea plana (CNA2) that manifests decreases in vision acuity due to the fla
105 imeric recombinant bovine-human PIV3 viruses that manifest different levels of attenuation in rhesus
106 genes could be causative for human diseases that manifest distinctive combinations of tissue-specifi
107 rast, female-predominant autoimmune diseases that manifest during the acute phase, such as Graves' di
108 provokes neutrophil-induced vascular leakage that manifests during the physical movement of neutrophi
110 ce in the N74D reverse transcription complex that manifests early after infection and prior to intera
111 ough a number of mutants have been described that manifest ectopic organ fusion, little is known abou
112 lar FLIP long transgenic (c-FLIP(L)-Tg) mice that manifest elevated caspase activity have greatly red
114 and causes decelerations in statural growth that manifest gradually over time.To illustrate an appro
116 t deficient in lysosomal cysteine cathepsins that manifests hallmarks of human lysosomal storage dise
119 6 (59.5%) of NPDR and 28 (70.0%) of PDR eyes that manifested improvement at 1 year maintained improve
120 myriad of genetic and biochemical processes that manifest in a final common pathway of physical impa
121 nic traumatic encephalopathy-like conditions that manifest in a singular manner throughout the white
123 ecipitating neurodevelopmental abnormalities that manifest in adults and/or G1/S cell-cycle dysregula
124 ssociated with inherited cobalamin disorders that manifest in both severe homocystinuria and methylma
126 es in function among costimulatory molecules that manifest in distinct pathologies of allograft rejec
130 hyperproliferation and autoimmune phenotypes that manifest in mice lacking E3 ubiquitin ligases such
131 the evolutionary stage for later refinements that manifest in modern humans as language-based convers
134 ore cystic component; and distant metastases that manifest in unusual sites (disseminating phenotype)
135 t, patient mutations Ala236Gly and Arg477Lys that manifest in XLT without progressing to WAS do not d
137 273R RdRp in vitro was increased by 2-3-fold that manifested in a 2-3-fold increase in the diversity
138 % of normal birthweight) is more severe than that manifested in either class of single Igf1r or Igf2
139 reatment elicited a highly specific response that manifested in elevated levels of metallothionein is
140 ospital complaining of persistent chest pain that manifested in the evenings and early mornings.
141 mune alteration in T1D patients and siblings that manifests in an exaggerated CD4(+)Tem response and
143 ct of 4-aminobutyric acid (GABA) degradation that manifests in humans as 4-hydroxybutyric (gamma-hydr
144 ut a description of real sensory computation that manifests in improved behavioural performance.
145 er (ASD) is a behaviorally defined condition that manifests in infancy or early childhood as deficits
146 wo different signals results in a new signal that manifests in late flowering, low protein oxidation
147 aining the shared cerebellar motor phenotype that manifests in mutants of the mGluR1 and GluRdelta2 s
150 an autosomal-dominantly inherited condition that manifests in the second half of life and is genetic
151 compounds from the thiosemicarbazone family that manifest increased growth inhibitory activity in mu
152 IRPalpha-deficient (Sirpalpha(-)/(-)) mouse, that manifests increased erythropoiesis as well as heigh
154 ed to direct effects of climate from effects that manifest indirectly through species turnover across
155 cardinal vein into a second arterial vessel that manifests intact arterial gene expression, interseg
156 fect and the easy accessibility of the cells that manifest it have made it a favorite tool of biochem
157 mbrane protein 1 (LMP-1) is a viral oncogene that manifests its oncogenic phenotype through activatio
158 d with intracellular C. neoformans residence that manifested itself in impaired cell cycle completion
159 sorders was diminished autonomic flexibility that manifested itself throughout the day, accompanied b
160 lated loss of accommodation of the human eye that manifests itself as inability to shift focus from d
161 ing and the toxicity of the infectious agent that manifests itself as progressive vacuolar neurodegen
162 i into a multifactorial developmental output that manifests itself as root system architecture (RSA).
163 reducible imprecision in such climate models that manifests itself as structural instability in clima
164 f the CEC system engender migration behavior that manifests itself in a relatively narrow elution win
167 yndrome is an X-linked hematopoietic disease that manifests itself in platelet deficiency and a compr
168 , first a rapid swelling of axonal processes that manifests itself in relative impedance above contro
169 ween vibrations of the beta-sheet, a process that manifests itself in the 2D IR spectrum as a frequen
171 s varies with the motor context, a mechanism that manifests itself in the phase-locked entrainment of
172 ed by overall disruption of the folded state that manifests itself in three ways: (1) dramatically re
174 report and explain an ice removal mechanism that manifests itself simultaneously with freezing, driv
177 aterials in the form of emergent excitations that manifest like point charges, or magnetic monopoles.
178 e studies have produced novobiocin analogues that manifest low micromolar activity against several ca
179 eneration of a murine Ptpn14 gene trap model that manifested lymphatic hyperplasia with lymphedema.
180 TPs, the RNA primer is extended in a process that manifests most of the properties of in vitro transc
183 Auxetics comprise a rare family of materials that manifest negative Poisson's ratio, which causes an
184 est and lethality by E11 of Hif1a-/- embryos that manifested neural tube defects, cardiovascular malf
185 ic and organic components to yield materials that manifest new functionalities unattainable in tradit
186 concentrations may cause subclinical effects that manifest only when triggered by a stressor, suggest
187 nd quantified a form of bacterial chemotaxis that manifests only as an emergent property by measuring
188 Many plant pathogens cause disease symptoms that manifest over days as regions of localized cell dea
190 es are used here to derive a molecular clock that manifests persuasive evidence that Nrf2 orthologues
191 ys were seen in all SLE B lymphocyte subsets that manifested phenotypic features of immature, mature,
193 n female presented with gingival enlargement that manifested postpartum and was most likely related t
194 Non-noviosylated coumermycin A1 analogues that manifest potent antiproliferative activity resultin
195 t a robust model of cutaneous carcinogenesis that manifests precancerous lesions and SCCs resembling
196 liferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in v
197 erize a series of transgenic FUS mouse lines that manifest progressive, mutant-dependent motor neuron
198 sts identified longitudinal bacterial series that manifested progressive changes in liquid media grow
200 e developed a transgenic mouse model of OPMD that manifests progressive muscle weakness accompanied b
201 ve been several descriptions of mouse models that manifest select immunological and clinical features
202 cycline contains ionizable functional groups that manifest several species with charges at different
208 se) into G6Pase-deficient (G6Pase(-/-)) mice that manifest symptoms characteristic of human GSD-1a.
211 for the design of protein-mimetic oligomers that manifest the folding encoded in natural amino acid
213 and demonstrate novel graphene metasurfaces that manifest the potential to dynamically control the p
215 ntified, we generated a knockout mouse model that manifested the phenotype and studied the mechanisms
216 the design and isolation of a peptide binder that manifests the most subtle kind of discrimination of
217 ancer cell lines and serve as lead compounds that manifest their activities through Hsp90 inhibition.
218 nduced by antagonistic epithelial morphogens that manifest their pattern-generating actions mechanica
219 rnal-effect and five paternal-effect mutants that manifest their phenotypes at the time of, or after,
220 tly, we identified numerous genetic variants that manifested their regulatory effects exclusively on
221 normal behavior and of diseases of the brain that manifest themselves as behavioral abnormalities.
223 difficult to ascribe causality to processes that manifest themselves at the level of the entire orga
226 ve been predicted to form a molecular system that manifests this peculiarity under natural conditions
227 ts in the N-linked glycosylation pathway and that manifest through impaired neuromuscular transmissio
228 with hyperapobetalipoproteinemia (hyperapoB) that manifest two acylation-stimulatory defects, decreas
230 transgenic ablation of brown adipose tissue that manifests typical metabolic complications of obesit
233 lecular C-H silylation of unactivated arenes that manifests very high regioselectivity through steric
234 of inflammation --> damage --> inflammation that manifests via organ-specific inflammatory switching
235 ygosity (ROH) are important genomic features that manifest when identical-by-descent haplotypes are i
238 surface-positive cells underwent activation that manifested with cell proliferation and/or up-regula
239 r-Willi syndrome (PWS) is a complex disorder that manifests with an array of phenotypes, such as hypo
241 eye disease (TED) is a degenerative disease that manifests with detrimental tissue remodeling, myofi
242 ecessive disorder caused by an MCM8 mutation that manifests with endocrine dysfunction and genomic in
243 managing neurogenic orthostatic hypotension that manifests with falls or cognitive impairment, but w
245 inuria (PNH) is a rare clonal blood disorder that manifests with hemolytic anemia, bone marrow failur
246 (PNH) is a rare bone marrow failure disorder that manifests with hemolytic anemia, thrombosis, and pe
247 mplex (TSC) is a multisystem genetic disease that manifests with mental retardation, tumor formation,
248 -onset, inherited neurodegenerative disorder that manifests with personality changes, movement disord
249 ular AMD, while its role in nonexudative AMD that manifests with progressive retinal pigment epitheli
250 e changes in the physician-patient encounter that manifested within 2 weeks of EHR transition and the
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