1 Our results support
the concept that (
18)F-NaF is a feasible option in imagi
2 us, in patients with traumatic brain injury,
the concept that 90 mm Hg represents a unique or importa
3 The study supports
the concept that a better understanding of the factors t
4 These findings bolster
the concept that a combined hepatic specific action of P
5 In conclusion, our data support
the concept that a dichotomous functional organization,
6 Experimental evidence supports
the concept that Abeta multimers can act as seeds and st
7 e findings of this study are consistent with
the concept that abnormal AAT protein conformation and i
8 This contrasts with
the concept that accumulation of myeloid cells at ischem
9 Together, these results support
the concept that activating Stat1 in the presence of JAK
10 These data support
the concept that activation of ERBB family members is su
11 Included in this rubric is
the concept that activation of the inflammasome, a molec
12 Recent evidence supports
the concept that AD can also recognize other comorbiditi
13 a risk factor for pediatric AIS, and support
the concept that ADAMTS13 has a role in the pathogenesis
14 ting cardiac aging and function, challenging
the concept that aging is an inevitable process in the h
15 ing evidence has been provided in support of
the concept that airway basal cells are central to the p
16 Growing in vivo evidence supports
the concept that airway smooth muscle produces various i
17 Central to Value-Based Medicine is
the concept that all patients deserve the interventions
18 the mechanism of SIT and we will put forward
the concept that allergens may be viewed as 'protoxins'
19 In addition, it reinforces
the concept that allogeneic HSCT offers optimal eradicat
20 These findings introduce
the concept that allostery in proteins could have its or
21 SPI1 by affecting HilD stability, supporting
the concept that altering the stability of this regulato
22 These results reinforce
the concept that alternate activation profiles control M
23 These findings support
the concept that an amplification process occurs along t
24 Our findings support
the concept that an autoimmune process directed at aorti
25 rmal neurobehavioral development and support
the concept that antibiotics and other environmental che
26 These new insights herald
the concept that astrocytes represent a diverse populati
27 Sporadic evidence supports
the concept that autoantibodies may cause cardiac arrhyt
28 Overall, this study supports
the concept that autoimmunity is a causative parameter t
29 der the possibility of iterated development,
the concept that behavioral and life history trajectorie
30 Together, the data support
the concept that beta cell killing occurs sporadically d
31 Our results support
the concept that beta-blocker drugs may improve the surv
32 e results lead to a paradigm shift away from
the concept that binding of the anti-beta2GP1 autoantibo
33 Evidence from multiple studies supports
the concept that both glomerular filtration and proximal
34 ive in driving acrosomal exocytosis supports
the concept that both NAADP-gated cascades match local N
35 vaginal bacterial species between women and
the concept that BV is sexually transmitted.
36 The concept that c-kit expression in the adult heart ide
37 These results support
the concept that Ca(2+) influx through single TRPV4 chan
38 Substantial evidence supports
the concept that cancers are organized in a cellular hie
39 tion during progression of T1D and reinforce
the concept that candidate genes for T1D may affect dise
40 pendent of IL-1-family signaling, supporting
the concept that caspase-1 influences lipid metabolism t
41 rpinning the vision of precision medicine is
the concept that causative mutations in a patient's canc
42 expressing anti-stress DCT molecule supports
the concept that CAV1 functions as a tumor suppressor in
43 Taken together, these data strengthen
the concept that CD4 T cell effectors are broadly multif
44 These findings support
the concept that CD44 mediates several of its effects on
45 The concept that certain aggregation-prone proteins can
46 These findings provide strong support for
the concept that changes in diet and gut environment are
47 to interferon-gamma stimulation, validating
the concept that chemical inhibition of mPTPB may be the
48 ry, these molecular genetic findings support
the concept that classic pleuropulmonary SFT and deep-se
49 ailed to improve patient outcomes, promoting
the concept that clinically important oxidative stress m
50 ative of subpial cortical pathology supports
the concept that common CSF-mediated factors might play
51 Our analysis reinforces
the concept that compartmentalisation influences Ras sig
52 These data support
the concept that cross-talk between the Wnt/beta-catenin
53 ion of the heterogeneity of CRS has promoted
the concept that CRS consists of multiple groups of biol
54 ken together, our results firmly corroborate
the concept that CTMP promotes Akt phosphorylation and f
55 ncipient gynoecial primordium and strengthen
the concept that cytokinin regulates auxin homeostasis d
56 These findings provide molecular support for
the concept that defective inflammation resolution contr
57 These studies have solidified
the concept that deficits in mass balances for chloroeth
58 Our findings support
the concept that defined bacterial products can be explo
59 also provide additional evidence supporting
the concept that desensitization and internalization are
60 The concept that diagnostic and theranostic sensors can
61 These data provide support for
the concept that dietary recommendations developed for o
62 These results support
the concept that different IFT proteins are responsible
63 epithelia from patients with IBD, supporting
the concept that disrupted barrier function contributes
64 Increasing data support
the concept that disruption of normal neural stem and pr
65 These findings reinforce
the concept that disruption of the functions of PML-NB p
66 omain was the most specific, consistent with
the concept that domain insertions drive the evolution o
67 These data highlight
the concept that drug-resistant cells may also display d
68 Findings challenge
the concept that durable polymers are key in VLST format
69 Transplacental immune regulation refers to
the concept that during pregnancy, significant cross-tal
70 Our findings support
the concept that dysregulated eIF2alpha phosphorylation,
71 el in responders to antidepressants supports
the concept that dysregulation of brain arousal is a pos
72 tiple markers to classify patients, based on
the concept that each individual marker contributes info
73 Overall, this study supports
the concept that early assessment of urinary antimicrobi
74 These data support
the concept that early vascular changes are involved in
75 The results support
the concept that Ebola virus infection is self-contained
76 ote phagocytosis of apoptotic cells, support
the concept that EBOV relies on apoptotic mimicry to inv
77 Our results support
the concept that EC Kir2 channels boost vasodilatory sig
78 The concept that EGFR oncogene inhibitor drugs could be
79 These results support
the concept that EGFRt represents a promising approach t
80 Recently,
the concept that endogenous stem/progenitor cells could
81 These data support
the concept that endothelial dysfunction due to high cir
82 enesis/vasculogenesis, providing support for
the concept that ENOX1 represents an antiangiogenic drug
83 These findings support
the concept that eosinophils might act as antigen-presen
84 Our findings support
the concept that ErbB3 exists in preformed clusters that
85 It also reinforced
the concept that ERVs are causative agents of many cance
86 We investigated
the concept that erythrocyte membrane microparticles (MP
87 The concept that excess superoxide production from mitoc
88 These data provide support for
the concept that exercise engages epigenetic control mec
89 Our findings offer in vivo validation of
the concept that exosome secretion can exert key pathoph
90 There has been increasing interest in
the concept that exposures to environmental chemicals ma
91 t further advancement of TDF IVRs as well as
the concept that extended duration drug delivery devices
92 These data are compatible with
the concept that FGF21 functions physiologically as an i
93 Our data support
the concept that FIH-1 may interact with Notch2 and repr
94 Our findings support
the concept that focal seizures are terminated by the si
95 We tested
the concept that gene imbalance across an extra chromoso
96 Fundamental to network analysis is
the concept that genes underlying the same phenotype ten
97 Our study supports
the concept that genomic instability contributes importa
98 lity and proliferation increase; this led to
the concept that glia are required for maintenance of th
99 reduced TNF-alpha synthesis, which supports
the concept that glycerophosphoinositol inhibits the de
100 Moreover, these results support
the concept that GR protein-protein interactions are not
101 with theoretical considerations, has led to
the concept that granule cells encode afferent input as
102 Together, these data support
the concept that granulomas have organized microenvironm
103 These results challenge
the concept that haploinsufficiency is a unifying mechan
104 sults in a small sample, they are a proof of
the concept that HER2-targeted imaging can identify addi
105 Support for
the concept that herpes simplex virus type 1 (HSV1), whe
106 These data support
the concept that HFS conditioning of the sciatic nerve,
107 climate change concerns, this work supports
the concept that high rice yields can be achieved with m
108 polarization (PHIP) was used to demonstrate
the concept that highly polarized, catalyst-free fluids
109 Our finding reinforces
the concept that HLA compatibility significantly influen
110 Together, these data support
the concept that human Helios(-) memory Tregs encompass
111 The concept that hypnozoites give rise to relapses in Pl
112 The results support
the concept that Id-specific Th cells may trigger the de
113 These results support
the concept that IL-1Ra modulates MCL-localized granulat
114 Emerging evidence supports
the concept that immune cells become activated and enter
115 These data support
the concept that immunisation of devils with DFTD cancer
116 These results support
the concept that in vivo, cumulative signals from the mi
117 The concept that individuals with the same disease and a
118 ur results provide a molecular framework for
the concept that induced changes to the heterochromatic
119 These findings support
the concept that inflammasome activation is connected to
120 Excitingly,
the concept that inflammation may be the core of cardiov
121 to the term "colitis-associated cancer" and
the concept that inflammation promotes colon tumorigenes
122 These findings support
the concept that inhibition of apoB synthesis traps lipi
123 tic input zones and dendritic fields support
the concept that interlaminar communication is mediated
124 mprehensive assessment of fatness reinforced
the concept that intraabdominal fat compartment is stron
125 The results of this study remark
the concept that IOP is a dynamic parameter and that int
126 However,
the concept that it is not just the absence or presence
127 oxidants ebselen and TEMPOL, consistent with
the concept that it requires an oxidising shift in the c
128 In conclusion, our data support
the concept that Jak2-Stat5a/b signaling promotes metast
129 a key regulator of metastasis and establish
the concept that K14(+) epithelial tumor cell clusters d
130 Drug design is built on
the concept that key molecular targets of disease are is
131 Our data do not support
the concept that KIR-HLA matching might serve as a tool
132 find substantial genetic evidence to support
the concept that lineage-determining transcription facto
133 s in arterial wall inflammation and supports
the concept that lipoprotein-lowering therapies may impa
134 Our findings support
the concept that localized, acquired SIgA deficiency in
135 r61 induction and cell migration, supporting
the concept that LPA1 is required for Cyr61 expression a
136 These data refute
the concept that macrophages are dominantly cleared thro
137 Previous observations supporting
the concept that maintenance of the intestinal epitheliu
138 These findings are consistent with
the concept that male fetuses are more aggressive with r
139 These data support
the concept that medication adherence is modifiable via
140 These preliminary data support
the concept that microbe survivorship and diversity are
141 otubule dynamics in neurite outgrowth led to
the concept that microtubules directly drive plasma memb
142 These findings support
the concept that microvascular dysfunction precedes and
143 eloped an innovative approach by introducing
the concept that mitochondrial targeting peptides (MTP)
144 This supports
the concept that MM41 (and by implication other quadrupl
145 -terminal region of the protein, and support
the concept that modulating mutant HTT conformation migh
146 rise to lesional macrophages has reinforced
the concept that monocyte infiltration dictates macropha
147 This method is based on
the concept that most energy required for neuronal commu
148 & CLINICAL RELEVANCE: These findings support
the concept that mother's milk has a distinct antifood a
149 The concept that motor disorders of the gallbladder, cys
150 These results all support
the concept that mRGC degeneration is a contributor to c
151 o eruption, supporting and further extending
the concept that Msx2 controls formation of mineralized
152 These results are consistent with
the concept that Nanog-negative cells may contain subpop
153 These results support
the concept that Nef adopts its active conformation in t
154 in neurons and cortical circuits, supporting
the concept that neonatal gene therapy may prevent the f
155 de direct biologic and molecular support for
the concept that neuroendocrine transdifferentiation in
156 T and the severity of MDE is consistent with
the concept that neuroinflammation in specific regions m
157 These results support
the concept that nitrate-rich vegetables may reduce the
158 ved in human metastatic melanoma, supporting
the concept that NLRC4 expression controls tumor growth.
159 In contrast,
the concept that NLRs can inhibit innate immunity is sti
160 -IgG can cause miscarriage, thus challenging
the concept that NMO affects only the CNS.
161 Recent studies have raised
the concept that non-alcoholic fatty liver disease (NAFL
162 Several investigations support
the concept that non-neuronal cells (microglia, astrogli
163 Finally, these data confirm
the concept that normal stroma function is essential for
164 to immunosuppression, these findings support
the concept that Notch inhibitors could be attractive fo
165 inflammatory response persists, underscoring
the concept that NTHi induces dysregulation of normal in
166 This study supports
the concept that nTS astrocyte transporters influence sy
167 ecular analysis of OCBs and strongly support
the concept that OCBs are not merely the terminal result
168 In agreement with
the concept that once infection is established high leve
169 Taken together, these data refute
the concept that ongoing HIV replication is common with
170 Overall these findings reinforce
the concept that orthogonal E-cadherin-based signaling p
171 Taken together, these results support
the concept that OSA exacerbates the cardiometabolic ris
172 These data support
the concept that OSE (MAA-epitopes), which are ubiquitou
173 These data corroborate
the concept that osteoblasts modulate the inflammatory r
174 Overall, our findings support
the concept that perturbations in host-microbiota intera
175 original genetic association and supporting
the concept that pharmacological inhibition of ADAMTS7 s
176 urvival of intestinal stem cells and support
the concept that pharmacological quiescence is a potenti
177 We also propose
the concept that phosphatidylserine recognition receptor
178 unreported pathway of photoaging and support
the concept that photoaging is at least in part a proces
179 Of importance, our data challenge
the concept that PI3Kgamma is required for insulin secre
180 In this study we propose
the concept that pollen grains can be engineered for use
181 We also find little support for
the concept that polymerase uncoupling, where extensive
182 ese results provide an empirical example for
the concept that population-based linkage analysis is a
183 d away from the direction of movement favors
the concept that posterior parietal cortical mechanisms
184 Our findings support
the concept that PPG value <12 mm Hg after TIPS placemen
185 derstanding of prion replication and support
the concept that prion replication can be separated from
186 The concept that proteins and small RNAs can move to and
187 The results support
the concept that "
proteostasis" mechanisms, such as intr
188 TP-mediated biochemical events and reinforce
the concept that PTPs are indispensable and specific mod
189 These results motivate
the concept that RA resistance can occur in steps, where
190 s an increase in cancer risk consistent with
the concept that RAP80 exhibits a tumor suppressor funct
191 Our results lead to
the concept that reduced Ca(2+) buffering enables fast a
192 This preclinical study supports
the concept that reduced toxicity with similar efficacy
193 These results bring forward
the concept that reversing Arc abnormalities could provi
194 quantitative trait loci analysis, supporting
the concept that risk genes cluster in pathways.
195 Furthermore, we present
the concept that RNA modifications can impair RNA-depend
196 , and reporter and mutation analysis support
the concept that RORgamma regulates the transcription of
197 f Avpr1a depends on RORgamma consistent with
the concept that RORgamma1 provides a link between the c
198 thesis of therapeutic hNGF but also supports
the concept that salivary gland from TG animals is an ef
199 d among different biological systems, and so
the concept that scaffolding complexes might not always
200 is massively enlarged, which is in line with
the concept that SCYL1 regulates Golgi integrity.
201 Taken together, our data support
the concept that SDF-1 regulates the spatial distributio
202 ecies-level vertical inheritance, supporting
the concept that secondary metabolites represent functio
203 CS1 transporters, and in particular, forward
the concept that selective channel-like gates might cont
204 Our findings reinforce
the concept that sentinel nodes act as pivotal sites for
205 The study does not therefore support
the concept that severe asthma is associated with cortic
206 ctional studies in vivo and in vitro support
the concept that Shank3 is critical for synaptic plastic
207 These studies provide support for
the concept that similar epigenetic modifications may un
208 The concept that similar pathways control both bone remo
209 These results further support
the concept that SM proteins in general are part of the
210 These observations support
the concept that some bacteriophytochromes can function
211 These observations support
the concept that some DOCK8-immunodeficient patients hav
212 The concept that some of the myocytes that die after suc
213 Taken together, these results support
the concept that Sp1 and Sp3 are functionally involved a
214 complex and non-overlapping minor complexes;
the concepts that specify the quality of an experience a
215 upon prolonged serum deprivation, supporting
the concept that ST6Gal-I confers a survival advantage.
216 Pneumocystis CONCLUSIONS: These data support
the concept that stimulation of preexisting immunologica
217 Therefore, our data support
the concept that store-operated Ca(2+) channels in hPECs
218 Our data support
the concept that strategies aimed at enhancing hepatic b
219 Results of this study support
the concept that stress-induced activation of KOR by end
220 ectively, these pre-clinical data help prove
the concept that subcutaneous and subconjunctival inject
221 The concept that surface chemistry at the (sub)nanometer
222 These results support
the concept that syntaphilin-mediated immobilization of
223 The concept that T lymphocytes are positively selected i
224 We investigated and validated
the concept that target drug concentrations associated w
225 The concept that target tissues determine the survival o
226 results of this study establish the proof of
the concept that targeted HNPs can enhance the therapeut
227 of HER2-positive breast cancer, highlighting
the concept that targeted therapies are successful when
228 induction of apoptosis, and strongly support
the concept that targeting MCC dependence on these molec
229 Overall, these data provide support for
the concept that targeting metabolic and anti-apoptotic
230 Together, these studies support
the concept that targeting Snail/Slug-dependent transcri
231 Our results are consistent with
the concept that Tbr2(+) neural precursor cells were pre
232 Our results strongly support
the concept that TEIPPs derive from ubiquitous, nonmutat
233 Our results extend
the concept that telomere length affects risk of lung ca
234 our findings provide additional support for
the concept that the anatomic and genetic etiological ba
235 Further, our results indicate proof of
the concept that the assay can be used to detect Histopl
236 These results support
the concept that the balance of TIMP3 and ADAM17 activit
237 Our results are consistent with
the concept that the beneficial action of PI3Kgamma abla
238 These data substantiate
the concept that the continuity of SC endothelium is an
239 he replicon to replicate, further supporting
the concept that the correct positioning of both the bet
240 fined in the mathematical sense, and support
the concept that the defining mechanism is a stable grou
241 We also found evidence supporting
the concept that the effects on microphthalmia-associate
242 egulation and cell cycle control, supporting
the concept that the established GABAergic dysfunction i
243 Our data support
the concept that the exocyst-complex subunits dynamicall
244 These findings support
the concept that the folding trajectory of SERT is sampl
245 The concept that the full effects of CPCs require repeat
246 Operating under
the concept that the GFD benefits only individuals with
247 ere we provide an experimental validation of
the concept that the HD dialytic removal of PBUTs can be
248 This report represents proof of
the concept that the human fetal biliary tree stem cells
249 clusion, we provide preclinical evidence for
the concept that the immunomodulatory properties of H. p
250 activated G proteins, these findings support
the concept that the inhibitory effects of SPL on M3R ac
251 Their results support
the concept that the lymphatic vessel route is critical
252 Our data support
the concept that the major autophosphorylation site (Thr
253 These results support
the concept that the measured behavior of glaucomatous V
254 However, recent studies support
the concept that the MR also has extrarenal actions and
255 Our data suggest
the concept that the multi-PDZ-domain adaptor protein GR
256 The intent of this review is to develop
the concept that the multifaceted therapeutic effects of
257 These results support
the concept that the onset of familial amyloid disease i
258 In general, the results are compatible with
the concept that the overall severity of the disease dep
259 over the primary linoleate products enhances
the concept that the oxidations disrupt corneocyte membr
260 These findings have attested to
the concept that the paracellular pathway is physiologic
261 These studies support
the concept that the perithrombus endothelium is the pre
262 Our findings strengthen
the concept that the PMV is part of the vomeronasal syst
263 Collectively, a solid basis is provided for
the concept that the probability of cyst formation is de
264 el that captures these features, building on
the concept that the ribbon under the imposed deformatio
265 These data support
the concept that the ROCK pathway could represent an imp
266 mpaired in APRIL-deficient mice, questioning
the concept that the same factors account for attraction
267 In line with
the concept that the structural modules of ANF-RGC are d
268 Our results support
the concept that the TCR can continue to signal after it
269 his discovery provides additional support to
the concept that the TMED family members are important p
270 These results support
the concept that the topographic connections between the
271 e basis of a H-tunneling mechanism that uses
the concept that the tunneling of a heavier isotope requ
272 l)-S-phenylglycine t-butyl ester, supporting
the concept that the two compounds act at the transcript
273 ausing acute disease, thereby giving rise to
the concept that the virome is a component of the microb
274 Thus, our results support
the concept that the ZO-1 shuttle from the cell junction
275 The data support
the concepts that the exRNA/RNase1 system participates i
276 Our findings support
the concept that therapies targeting FGFR signaling may
277 g can account for variations in CV, and that
the concept that there is massive redundancy of coupling
278 there is limited genetic evidence to support
the concept that these boundaries restrict the search sp
279 formoterol to interact in this way supports
the concept that these drugs together may impart clinica
280 They support
the concept that this dietary lifestyle can act as a ris
281 al epidemiological studies in humans support
the concept that this enzyme is intimately involved in U
282 This study tested
the concept that this female advantage associates with a
283 Our findings do not support
the concepts that this phase is devoid of markers of dis
284 This leads to
the concept that tissue regeneration required stimulatio
285 Here we discuss
the concept that TNTs/TMs fill an important niche in the
286 Together, our study supports
the concept that transcriptional suppression of KV2.1 by
287 icity and tissue regeneration and introduces
the concept that transient therapeutic delivery of senes
288 of TNFalpha promoter activation, supporting
the concept that TRIF-dependent signalling plays an impo
289 These findings support
the concept that TSLP plays a role in the development of
290 ental models of breast cancer, we reinforced
the concept that tumor-infiltrating gammadeltaT17 cells
291 The concept that tumor-initiating cells can co-opt the s
292 on of key computational predictions supports
the concept that understanding the molecular complexity
293 An important emerging area is
the concept that unregulated [Ca(2+) ]i signals in cells
294 This finding supports
the concept that uptake and efflux at monoamine transpor
295 se findings provide a powerful validation of
the concept that variability in brain signals reflects f
296 Our results are in line with
the concept that very high levels of specific humidity,
297 Overall, these data develop
the concept that VgrGs are indispensable components for
298 This has been used to support
the concept that viral reactivation in HCMV carriers rou
299 ice sites disrupting splicing and introduces
the concept that VWF splicing is affected by shear stres
300 In vitro assays support
the concept that Wls acts in part via Wnt5a to regulate