ライフサイエンスコーパス: the exploration of

1 The virtual screening step comprised the exploration of a chemical library with 11,000 compou

2 es their visual data summaries, facilitating the exploration of a hidden continuum.

3 coarse-grained structural ensemble, allowing the exploration of a large configurational space.

4 design of pooled genetic screens by enabling the exploration of a large space of experimental paramet

5 Here we report the exploration of a magnetically enhanced photon-transp

6 The exploration of a new crystalline R-state P2(1)2(1)2(

7 Thus, the exploration of a new judicious synthetic strategy is

8 esis and combinatorial chemistry can lead to the exploration of a range of structural candidates and

9 Our previous efforts focused on the exploration of a series of analogues related to scre

10 om emerging imaging modalities, have lead to the exploration of a variety of therapeutic intervention

11 tion of the cap module was a major factor in the exploration of a vast substrate space in the course

12 erve as a novel sensing principle to augment the exploration of a wide range of biological systems.

13 This opens new avenues for the exploration of adaptation of mammalian cells to grav

14 ctive nature of the calculations has allowed the exploration of additional derivatives based on the 8

15 ic eradication of bacterial colonization and the exploration of agents specifically targeting bacteri

16 M-8138 is an important new tool compound for the exploration of allosteric modulation of COX enzymes

17 ibiotic-resistant bacterial strains requires the exploration of alternative antibacterial therapies,

18 t broad-spectrum antibiotic classes warrants the exploration of alternative approaches, such as antib

19 nsive drift in the Ndt80 regulon allowed for the exploration of alternative network structures withou

20 f silicon (Si) electron devices have fuelled the exploration of alternative semiconductors, with high

21 biosensor technology can greatly facilitate the exploration of alternative splicing biomarkers in di

22 s a complicated ethical issue that calls for the exploration of alternative testing methods to reduce

23 em cell and gene therapy technologies enable the exploration of alternatives to allogeneic islet tran

24 t years, one area of major interest has been the exploration of alternatives to the classical iodide/

25 pain who were undergoing MR examination for the exploration of an equivocal adnexal mass (January 20

26 ructure-based screening, each followed up by the exploration of analogue compounds as identified by l

27 From the exploration of antiphase boundaries in bilayer-perov

28 these same factors represent limitations for the exploration of available chemistry space and we argu

29 However, this process may involve the exploration of back-tracked and forward-tracked tran

30 The exploration of benzothiazolidines as alternative hyd

31 Molecular tools have revolutionized the exploration of biodiversity, especially in organisms

32 The strategy enables the exploration of biofuels beyond those naturally accum

33 The exploration of bioinspired assemblies not only allow

34 e epidemiological observations should inform the exploration of biological mechanisms that link obesi

35 identified through the program are enabling the exploration of biological pathways and therapeutic h

36 reatment progression are key motivations for the exploration of biomarkers for allergic rhinitis and

37 entation method provides a powerful tool for the exploration of biomechanical properties of other cyt

38 stocks to improve sustainability, prompting the exploration of bioprocesses for the production of ch

39 the behavior of growth cone filopodia during the exploration of both correct and off-target muscle fi

40 richment of the target region, thus enabling the exploration of both DNA sequence and structural dive

41 all, this analytical toolbox now facilitates the exploration of both spontaneous and adaptive heterog

42 pered by the lack of efficient approaches to the exploration of both the large number of possible ele

43 The exploration of brain epigenomes, which consist of va

44 This study extends the exploration of bridge hydroxylated azabicyclo[3.2.1]

45 existing network visualization tools enable the exploration of cancer genomics data, most biologists

46 n force and the mass of the structure enable the exploration of cavity optomechanical regimes in whic

47 nd a data analysis environment, facilitating the exploration of chemical and biological information a

48 pecial emphasis was placed toward maximizing the exploration of chemical diversity of the initial hit

49 The exploration of chemical space for new reactivity, re

50 ology of hormone-refractory prostate cancer, the exploration of chemotherapeutic combinations, novel

51 Our predictions provide a useful guide for the exploration of chromatin organization.

52 This makes the exploration of coherent quantum enhanced optimizatio

53 The document encourages the exploration of collaborative care models that should

54 eliminating established tumors and validate the exploration of combinatorial treatment regimens, whi

55 These studies provide a rationale for the exploration of combining antiangiogenic agents with

56 data sets and historical comparisons limits the exploration of community dynamics over time in natur

57 n, Tn-seq has the potential to contribute to the exploration of complex pathways across many differen

58 hore/fluorophore for measurement, it allowed the exploration of concentration ratios otherwise unatta

59 sicle is varied between 0.1-10 mol %, enable the exploration of concentration-dependent mechanisms fo

60 gether with new functionalities facilitating the exploration of conserved cis-regulatory elements and

61 The exploration of cooperativity in protein folding has

62 The exploration of copy-number variation (CNV), notably

63 However, the exploration of cyclic polymers is limited because of

64 Our system makes the exploration of data easily accessible and usable wit

65 The exploration of different ways to visualize genomic d

66 The exploration of disease states in which significant c

67 vanadium oxide nanosheets will contribute to the exploration of disordered structures from earth-abun

68 ven by advances in imaging techniques and in the exploration of diverse cellular processes.

69 ies in the human brain are mostly limited to the exploration of DNA methylation and posttranslational

70 Similar to how genomics is applied to the exploration of DNA, metabolomics is the qualitative

71 These data lay the groundwork for the exploration of EC therapies that can serve as adjuva

72 Robustness allows the exploration of ecological adaptations.

73 lness of stable isotope analyses as tools in the exploration of ecological niches.

74 rocessing of facial expressions, overlooking the exploration of emotional body language (EBL), its ca

75 ell-and that, in fact, they open the way for the exploration of entirely novel designs.

76 The exploration of epigenetic mechanisms recently led us

77 rk offers a preclinical proof of concept for the exploration of eritoran as a clinical treatment, wit

78 resistance, and they provide a rationale for the exploration of ERRalpha as a candidate drug target t

79 he way to new unexpected applications and to the exploration of exotic behaviour of confined fluids r

80 ons are a convenient and simple platform for the exploration of exotic phases of matter and for the c

81 It used SEE (Strategy for the Exploration of Exploration) to phenotype the locomot

82 d provides prospective model systems towards the exploration of extended oligomers with tailored chem

83 High-energy pulsed lasers enable the exploration of extreme pressures and temperatures, w

84 These studies support the exploration of FcgammaR antigen targeting to BDCA-3(

85 ive intends to cover my fruitful endeavor in the exploration of fluorine chemistry at the multidiscip

86 ensemble simulation method for accelerating the exploration of free-energy landscapes, which define

87 data set in a user-friendly platform enables the exploration of functional noncoding DNA to study gen

88 ervational biotechnology and has facilitated the exploration of fundamental biological mechanisms and

89 the formulation of policy interventions and the exploration of future trends.

90 describe QUADrATiC, a user-friendly tool for the exploration of gene expression connectivity on the s

91 he sequencing and identification of genes to the exploration of gene function.

92 The exploration of genetic variation in HvP5CS1 may faci

93 ndividual event level is a powerful tool for the exploration of genome plasticity in stressed cells.

94 ory of elastic normal modes is described for the exploration of global distortions of biological stru

95 datasets from other species and systems for the exploration of global genetic co-expression.

96 portion of human tumors with mutant p53, but the exploration of GRO1 as a potential target should tak

97 he glycophorin helix dimer is a paradigm for the exploration of helix-helix interactions in integral

98 tic tractability of the zebrafish will allow the exploration of heritable modifiers of such drug effe

99 or the design of phase switching devices and the exploration of hidden amorphous materials.

100 in aging through IKK modulation and motivate the exploration of HOCl use for clinical aims.

101 between selectivity, efficacy and safety is the exploration of how inhibitors interact with the huma

102 While the exploration of hypothalamic function has progressed

103 apult the fungal "mycobiome" center-stage in the exploration of IBD.

104 he importance of this work is established in the exploration of important factors related to the desi

105 Further, they support the exploration of inhibiting IM recruitment and functio

106 Fast dynamic simulation facilitates the exploration of initial parameters that serve as the

107 But despite the exploration of innovative molecular designs, it rema

108 ming research in genomic medicine, including the exploration of issues related to the genetic archite

109 niques to bind to alpha-synuclein, including the exploration of its effects on the in vitro aggregati

110 The exploration of its nature is now led by direct and i

111 elucidation of the exact role of DPP III and the exploration of its potential as a target of pain int

112 the enhanced behavioral variability reflects the exploration of kinematic parameters for less punishi

113 iability on DA and whether this may underpin the exploration of kinematic parameters.

114 This methodology should allow for the exploration of lanthipeptide variants with new or en

115 rdinated multiple view approach can simplify the exploration of large comparative genomic data sets,

116 from typical multiple sclerosis, and spawned the exploration of large datasets to model long-term dis

117 m large DNA libraries and greatly facilitate the exploration of large libraries of mutant enzymes for

118 trategy for estimating Ne dynamics, allowing the exploration of large multi-locus SNP datasets.

119 BiNChE aids in the exploration of large sets of small molecules produce

120 onstituent parts, making them a test bed for the exploration of light-matter coupling.

121 iprocal systems on chip have made imperative the exploration of magnet free alternatives.

122 These findings have led to the exploration of malonyl-CoA decarboxylase (MCD) as a

123 tian atmosphere has had a major influence on the exploration of Mars, especially by the implication o

124 IH and provides an important mouse model for the exploration of matriptase function in ARIH, as well

125 Our findings warrant the exploration of means to interfere with ST18-dependen

126 ygen vacancies on-demand provides a tool for the exploration of mesoscale quantum phenomena and engin

127 mented application specifically designed for the exploration of microarray gene expression data via c

128 ection of mutation after experimentation and the exploration of microbial communities in unprecedente

129 In order to advance the exploration of microbial secondary metabolism, we de

130 The exploration of mixed-metal oxides at the nanometer l

131 genetic and genomic studies have facilitated the exploration of molecular pathways.

132 The exploration of molecular structure-property relation

133 The present research had as its goal the exploration of molecular systems having three pi-moi

134 ther studies in molecular ecology, including the exploration of more complex behaviors, such as preda

135 nd processing entangled states should enable the exploration of multiparticle entanglement on an exte

136 GenoSets has been designed to simplify the exploration of multiple genome datasets and to facil

137 Furthermore, through the exploration of multiple network architectures, we we

138 This has spurred the exploration of nanomagnets for unconventional comput

139 articles as building blocks is essential for the exploration of nanoparticle-structured properties.

140 e," "model," and "make" are being applied to the exploration of nervous system function.

141 resonance imaging (MRI) has greatly extended the exploration of neuroplasticity in behaving animals a

142 many open questions in PCA pathobiology and the exploration of new avenues for future PCA management

143 ealth, and combatting these viruses requires the exploration of new avenues for targeting viral repli

144 or increased data-storage density is driving the exploration of new magnetic media.

145 torage density and non-volatility is driving the exploration of new materials in nanostructured form.

146 ides and also provide deeper insights toward the exploration of new metastable phases with exceptiona

147 seudoreplication arguments, does not promote the exploration of new methodologies and there is someth

148 plexity of biomedical research is leading to the exploration of new models for large-scale collaborat

149 Dynamic control of its bandgap can allow for the exploration of new physical phenomena.

150 polymerization (RDRP) have paved the way for the exploration of new possibilities in terms of both po

151 This result may lead to the exploration of new targeted treatment options in MCC

152 uently associated with this approach warrant the exploration of new therapeutic strategies.

153 ambient conditions is a crucial step towards the exploration of nonlinearities, macroscopic coherence

154 onal states, provide an ideal laboratory for the exploration of novel 1D physics, as well as quantum

155 ins are antibiotic resistant, which requires the exploration of novel antimicrobial approaches, inclu

156 unctionalisation strategies should encourage the exploration of novel chemical methodologies with tha

157 imalarial drugs, especially artemisinin, and the exploration of novel combinations, ideally with dist

158 The exploration of novel drugs to serve as a companion d

159 t of the antiviral silencing would allow for the exploration of novel features of virus-host interact

160 The exploration of novel inhibitors of the HCV NS4B prot

161 udy I show that both effects help accelerate the exploration of novel phenotypes through plasticity.

162 to the entire RP homologous series--enabling the exploration of novel quantum phenomena at a richer v

163 um information processing and metrology, and the exploration of novel quantum states of matter.

164 The exploration of novel solid electrolytes is critical

165 al tuning, while Cheng and Frank report that the exploration of novel space leads to a transient incr

166 When rodents engage in the exploration of novel stimuli, breathing occurs at an

167 This limitation hampers the exploration of novel structures for molecular device

168 CMML pathophysiology will hopefully lead to the exploration of novel targets that potentially would

169 lding-up provides additional opportunity for the exploration of novel thermoelectric properties from

170 The exploration of nutritional supplements to treat asth

171 Together, the exploration of OncoPPi led to a new biological model

172 ck of target-specific gene delivery--justify the exploration of other Ad serotypes as vector prototyp

173 This has prompted the exploration of other alternatives to generate new bo

174 rics (i.e. SIC, SIC(10) and SCIM(10)) permit the exploration of other important inequalities not dete

175 These are intriguing times in the exploration of other solar-system bodies.

176 The exploration of parameter space by dynamic simulation

177 ice leads to embryonic lethality, precluding the exploration of pathophysiological roles of BMK1 in a

178 hine-generated CVs can be used to accelerate the exploration of phase space and to reconstruct free-e

179 The exploration of phase space with this algorithm is sh

180 nanoscopic, atomically thin pores allow for the exploration of phenomena in ionic transport, and sug

181 ted genotypes which enhance the capacity for the exploration of phenotypic novelty.

182 insight into tumor cell behavior and allows the exploration of phenotypic transitions not easily mon

183 employed the SCX/IMAC enrichment strategy in the exploration of phosphoproteomes from several systems

184 The exploration of physiologic functions of Wnt proteins

185 strating the potential of OFDI to facilitate the exploration of physiological and pathological proces

186 hyrinoids and carbaporphyrinoids, allows for the exploration of porphyrin-like or porphyrin-unlike co

187 on of the associated phenotypic spectrum and the exploration of potential targeted treatment options.

188 omparative genomics toolbox that facilitates the exploration of precomputed orthologs among the 20 cu

189 toimmune and infectious diseases and lead to the exploration of promising glycoforms for antibody the

190 The exploration of protease substrate specificity is gen

191 herapy-induced alopecia, strongly encourages the exploration of PTH/PTHrP-R agonists and antagonists

192 cay of quantum emitters, possibly leading to the exploration of qualitatively different dynamics.

193 ondensed matter and modern atomic physics is the exploration of quantum phases of matter--in particul

194 close to the motional ground state, enabling the exploration of quantum physics in larger, more massi

195 ess web application has been established for the exploration of regional differences in allele freque

196 This led to the exploration of related scaffolds offering additional

197 ond its size, the advantage of PAGED lies in the explorations of relationships between gene sets as g

198 rostructural characteristics are crucial for the exploration of relevant devices.

199 On the other hand, the exploration of residual plant material derived from

200 eml analysis from parameter input through to the exploration of results.

201 betes, the more immediate benefit may be for the exploration of revascularized islet biology.

202 The exploration of Saturn by the Cassini/Huygens mission

203 We embarked on the exploration of scaffolds that retained such properti

204 key mechanistic insight recently garnered in the exploration of selective Heck reactions, we report h

205 cities within an enzyme superfamily requires the exploration of sequence space for adaptation to a ne

206 nd taking aliquots from the original pool on the exploration of sequence space in a doped reselection

207 The exploration of sequence space was accelerated by inc

208 This also allows the exploration of shared functional enrichments between

209 These results open up the exploration of skyrmions in nanowires for fundamenta

210 loss-of-function and provides a platform for the exploration of small molecule modulators of hPINK1.

211 The availability of oxasmaragdyrin allowed the exploration of smaragdyrin in recent years.

212 memory-efficient package named BS-SNPer for the exploration of SNP sites from BS-Seq data.

213 ed the advantages and necessity of humans in the exploration of space.

214 n and type of polymer attachment, allows for the exploration of specific molecular designs and result

215 oof of concept and mechanistic rationale for the exploration of SSTNIGF1R as an experimental therapeu

216 important aspect in pre-clinical research is the exploration of strategies to re-establish learning a

217 use of a dynamic compartmental model limited the exploration of structural sensitivities.

218 The exploration of such phenomena is making remarkably i

219 hese recent advances herald a new chapter in the exploration of susceptibility to breast cancer and a

220 x systems has provided a useful approach for the exploration of system-level characteristics and beha

221 ions or sequences of newer drugs, as well as the exploration of targeted biologic agents for patients

222 The rate and extent of the exploration of the available phase space of a bound

223 p query results to MeSH topics to facilitate the exploration of the biological significance of the se

224 selection of cheap-to-produce scaffolds and the exploration of the biologically relevant chemical sp

225 ffold-based navigation system, which enables the exploration of the chemical diversity of StreptomeDB

226 The exploration of the chemical potential of the nitro g

227 amics simulations provide powerful tools for the exploration of the conformational energy landscape a

228 It provides a rationale for the exploration of the CYGB pathway as a molecular targe

229 ultraviolet light triggered a golden age in the exploration of the diversity of sensory systems of i

230 ata suggest that mCH3 could not only help in the exploration of the dual mechanisms of the CH3 contri

231 plication of modeling approaches that enable the exploration of the dynamic properties of cells.

232 n scattering (QENS) is an important tool for the exploration of the dynamics of complex systems such

233 These results open a new avenue into the exploration of the effects and regulation of neuroge

234 Despite this information, the exploration of the effects that parasite infections

235 The exploration of the endogenous regenerative potential

236 ss of chromatin reorganization as central to the exploration of the genomic landscape.

237 At the heart lies the exploration of the Gibbs free-energy landscapes and

238 nst multidrug-resistant P. falciparum led to the exploration of the importance of this motif.

239 to design a new protein fold makes possible the exploration of the large regions of the protein univ

240 l approach thus provides a powerful tool for the exploration of the link between conformational diver

241 eloped web-based applications that encourage the exploration of the literature on human genetic assoc

242 ce spectroscopy has become indispensable for the exploration of the mechanical properties of proteins

243 ta provided here represent a rich source for the exploration of the mechanism of oil accumulation in

244 The exploration of the metabolic pathways confirmed the

245 "back to the roots" framework that comprises the exploration of the microbiome of indigenous plants a

246 t extend lifespan provide valuable tools for the exploration of the molecular basis for age-related c

247 e dynamics with zinc imaging will facilitate the exploration of the molecular pharmacology and plasti

248 g thin films and will provide a platform for the exploration of the nature of charge carriers and exc

249 zation to join the major subunits, including the exploration of the optimum masking group for the C18

250 of ordered multicomponent metamaterials and the exploration of the phase behaviour of hybrid systems

251 Moreover, it may facilitate the exploration of the physicochemical textures of molec

252 The exploration of the potential energy surfaces associa

253 These findings provide a platform for the exploration of the potential role of SF MSCs in join

254 gnostic and diagnostic information and allow the exploration of the prevalence of pulmonary hypertens

255 es provide a direct means for characterizing the exploration of the protein by oxygen.

256 6-DNA-methyltransferases, as determined from the exploration of the reaction mechanism in the Asn105A

257 congenic strains provide a new resource for the exploration of the relationship in Cryptococcus betw

258 captured, and there are few tools to assist the exploration of the remaining volume of unknown data

259 More generally, our approach facilitates the exploration of the role of arbitrary particle geomet

260 nsights into these conditions have triggered the exploration of the role of innate immunity in common

261 he fact that the information obtained during the exploration of the search space is used to guide fur

262 The power of the method is exemplified by the exploration of the six-dimensional free energy lands

263 Current plans for the exploration of the solar system include constraints

264 advances in optical techniques have enabled the exploration of the spatiotemporal aspects of the sig

265 se of parallel Monte Carlo Markov chains for the exploration of the species space enables the identif

266 It shall be demonstrated that the exploration of the underlying mechanisms is excessiv

267 f the S.aureus genome, we hope to facilitate the exploration of the unique biology of this organism a

268 Here, we hypothesize that the exploration of the vast and visually stimulating vir

269 um dynamics of quantum many-body systems and the exploration of their analogs in cosmology and astrop

270 ed to provide exciting new opportunities for the exploration of their functional applications.

271 s in V. unguiculata and can be integrated in the exploration of their genetic diversity for improveme

272 ethylenedioxythiophene), PEDOT, coupled with the exploration of their photoelectrochemical properties

273 viour enables the study of ice nanotubes and the exploration of their potential applications.

274 on cuprates using ionic liquids have enabled the exploration of their rich phase diagrams.

275 for ApiAP2 proteins lays the foundation for the exploration of their role as transcriptional regulat

276 Furthermore, the exploration of these graphs can expose structures an

277 lack of defined oligosaccharides has limited the exploration of these sugars as components of new the

278 t also provides a new framework for refining the exploration of these unique environments.

279 Our findings prompt the exploration of theta dynamics (using repeated electr

280 ion of ASICs has remained unknown, hindering the exploration of this line of therapy.

281 , and provides an important animal model for the exploration of this membrane serine protease in a ra

282 The exploration of this now demonstrated concept with ot

283 The exploration of this series led to the identification

284 The exploration of this series led to the selection of N

285 We predict that the exploration of three-dimensional genome architecture

286 organ rejection noninvasively that involves the exploration of tissue-infiltrating leukocytes as bio

287 Our work opens an exciting route for the exploration of topological physics in time-modulated

288 roblems or the difficulties they may pose in the exploration of trauma memories, an efficacious and f

289 h scientific attention has been attracted by the exploration of two functional processes linked to mi

290 The exploration of two-dimensional solids is an active a

291 These data warrant the exploration of TZD as preventive/therapeutic agent i

292 computer-assisted approach for accelerating the exploration of uncharted effective free-energy surfa

293 The exploration of unconventional shale energy reserves

294 al models of human disease are important for the exploration of underlying disease mechanisms as well

295 le and could open untapped opportunities for the exploration of unique quantum physics.

296 Our results open new possibilities in the exploration of universal dynamic conductance in plas

297 Here, we suggest that the exploration of vast and visually stimulating environ

298 itable and an evolvable template, permitting the exploration of vast genetic landscapes.

299 field of environmental virology by allowing the exploration of viral communities in a variety of sam

300 ate functional studies of Wnt signalling and the exploration of Wnt agonists for translational applic