ライフサイエンスコーパス: the first report of

1 ense change associated with human disease in the first report of a "PANX1-related disorder."

2 This is the first report of a bacterial GDP-regulated thioestera

3 To the best of our knowledge, this is the first report of a biosensor capable of detecting the

4 xtension of the MAX phase family, as this is the first report of a bismuth-based MAX phase.

5 This is the first report of a borrelial adhesin with a metal ion

6 eport of a grating-coupled BSW biosensor and the first report of a BSSW propagating mode.

7 To the best of our knowledge, this is the first report of a cellular protein that uses this ap

8 To our knowledge, this is the first report of a change in a central biomarker duri

9 This is the first report of a chemoreceptor that mediates QACs t

10 This is the first report of a chemotherapy-based animal model of

11 This was the first report of a clostridial organism containing mo

12 INTERPRETATION: To our knowledge, this is the first report of a combined implanted FES+iBCI neurop

13 reactivity to several filoviruses, including the first report of a cross-neutralizing antibody that e

14 To our knowledge, this is the first report of a DOE optimization for immunoassays

15 Although this is the first report of a Dot/Icm substrate being secreted b

16 Since the first report of a facile, room temperature process t

17 -NAD(P)H anomers in mammalian physiology and the first report of a flavoprotein catalyzing an epimeri

18 To our knowledge, this is the first report of a full-length octameric MCM helicase

19 This is the first report of a fully solution-processed nanomater

20 This is the first report of a functional amyloid from the archae

21 This is the first report of a functional catalytic triad enginee

22 This is, to our knowledge, the first report of a fungal subtilisin that shows elici

23 This is the first report of a gene causing subtle but consistent

24 independent SNPs around TF on chromosome 3, the first report of a genome-wide significant second ind

25 This is the first report of a germline competent F344 ES cell li

26 This is the first report of a grating-coupled BSW biosensor and

27 These results are the first report of a histone PTM significantly altering

28 This is the first report of a hospital-based cluster of Herbaspi

29 igh-resolution mass spectrometry, we provide the first report of a host-pathogen protein interaction

30 ssociated with chronic hemolysis constitutes the first report of a human disease caused by a defect o

31 Moreover, we describe the first report of a human mast cell antigen-dependent

32 This is the first report of a humanized model of the DEK-NUP214

33 This is the first report of a land plant possessing selenocystei

34 This is the first report of a large-scale identification and str

35 This is the first report of a LAT-related disease in humans, man

36 This is the first report of a lesional AD phenotype using RNA-se

37 This is the first report of a lipoprotein essential to the abili

38 ene encoding CD59; to our knowledge, this is the first report of a mammalian species that does not ex

39 To our knowledge, this is the first report of a MAP3K directly activating a MAPK b

40 This is the first report of a mechanism for the cooperative acti

41 To the best of our knowledge, this is the first report of a melanocortin bivalent ligand's in

42 To our knowledge, this is the first report of a molecular mechanism for organoarse

43 r host-pathogen interaction systems, this is the first report of a mosquito-associated fungus that ca

44 This is the first report of a mutation in the STAT1 sumoylation

45 pha-aryl ester pronucleophiles, representing the first report of a neutral Bronsted base to catalyze

46 Our study represents the first report of a new habitat of fungi associated wi

47 This work is the first report of a newly generated humanized transgen

48 This is the first report of a novel O-linked sulfonated peptidyl

49 To our knowledge, this is the first report of a patient with GEH associated with F

50 To our knowledge, this is the first report of a patient with multiple melanomas, d

51 This is the first report of a phase 3 vaccine efficacy trial of

52 This is the first report of a PI3Kalpha-selective inhibitor, and

53 To our knowledge, this is the first report of a protective role for PAT in skin ca

54 This is also the first report of a proviral function of IFITMs in DNA

55 To our knowledge, this is the first report of a randomized trial to prospectively

56 rylation-dependent signalling, and represent the first report of a regulatory mechanism for UIM-depen

57 This is the first report of a role for CD169 in the capture of e

58 As such, this represents the first report of a selective inhibitor of human 12/15

59 This is, to our knowledge, the first report of a significant effect of the matrix,

60 To our knowledge, this is the first report of a single ectopically expressed trans

61 This is the first report of a single mesophilic organism that ca

62 This is the first report of a single-pill, all-oral, interferon-

63 This is the first report of a specific export factor of a TAA, s

64 This is the first report of a syndromic SFD in line with the mou

65 This is the first report of a versatile mesoporous material that

66 To our knowledge, this is the first report of a viral protein disrupting NEMO-cIAP

67 This study represents the first report of a virally encoded sugar acetyltransf

68 To our knowledge, this is the first report of a virus encoding a miRNA that suppre

69 To our knowledge, this is the first report of a voltammetric immunosensor capable

70 This is the first reporting of a mouse model for MECD that recap

71 This is the first report of acute hepatic necrosis with liver fa

72 To our knowledge, this is the first report of adsorption isotherms of fluorocarbon

73 1 and TSLP-SLC25A46 loci and age at onset is the first report of age at onset effects in allergic rhi

74 This is the first report of AhrC serving as a virulence factor i

75 This is the first report of allopregnanolone use to treat status

76 This is the first report of an acute thrombotic vessel occlusion

77 r for one week, to the best of our knowledge the first report of an air-stable solution-processable n

78 This is the first report of an anti-inflammatory effect of a sys

79 This is the first report of an aphid-transmitted geminivirus.

80 To the best of our knowledge this is the first report of an application of online IEC MC-ICPM

81 This is the first report of an arginine finger observed in a sep

82 In addition, to our knowledge, this is the first report of an association between high AChR ant

83 This is, to our knowledge, the first report of an association between house dust en

84 The first report of an association between Th2 polarizat

85 This is the first report of an association between the BBSome co

86 To our knowledge, this is the first report of an association with Lyme disease.

87 To our knowledge, this is the first report of an attenuated EHV-1 vaccine that pro

88 Given that this is the first report of an effect of NAMPT inhibitors in col

89 This is the first report of an enzyme sensor strip using a fungu

90 This is the first report of an epigenetic-related disorder threa

91 This is the first report of an exceptionally facile double-isome

92 This is the first report of an experimental vaccine that induces

93 VAIT is the first report of an extraribosomal L13a-mediated, IFN

94 Finally, this work is the first report of an Eya-Ey physical interaction.

95 This study is, to our knowledge, the first report of an increase in heterozygosity follow

96 This is the first report of an intermediate period of EVNP in cl

97 s us to address questions such as: Following the first report of an invading pathogen, what is the li

98 This is also the first report of an MO Q-switch producing random pola

99 d community outbreak of serotype 12F IPD and the first report of an outbreak of IPD serotype 12F in a

100 are first reports of AGII in papaya pulp and the first reports of an in vitro biological activity of

101 This is the first report of anakinra for treatment of a child wi

102 This is the first report of anomalous large-scale gray matter st

103 This is the first report of antibody function in a human infecti

104 This is the first report of aptamers with strong selectivity for

105 This is the first report of aromatic C-H bond activation by a tr

106 From here, the virus spread to Brazil with the first report of autochthonous Zika transmission in t

107 This is the first report of AZD1775 single-agent activity in pat

108 smission of infection between neonatal mice, the first report of B. pertussis transmission in mice.

109 This is the first report of bacterial DNA in human breast ductal

110 This is the first report of bioaccumulation and partitioning beh

111 This is the first report of biomineralization of olekminskite an

112 ion, including an outbreak in Singapore, and the first reports of birth defects linked to ZIKAV in th

113 To our knowledge, these are the first reports of bloodstream infections by Trichospo

114 To our knowledge, this is the first report of Cam uptake into bacterial cells medi

115 To our knowledge, this is the first report of CaMKII activation triggering cellula

116 To our knowledge, this is the first report of CaMKII initiating cellular activity

117 This is the first report of CbK-like phages infecting marine bac

118 This is the first report of CCD in Hungarian Vizsla dogs and ide

119 This is the first report of cell cycle reentry in human myositis

120 To our knowledge, this is the first report of cerebellar cortical dysplasia in a f

121 This is the first report of cervical and dual-targeted intraspin

122 This is the first report of colloidal metal nanoparticles in the

123 ERPRETATION: To our knowledge, this study is the first report of common genetic variation conferring

124 This is one of the first reports of controllable and wavelength-selecti

125 This is the first report of copy number variation of human tRNA

126 To the best of our knowledge, this is the first report of cortical remodeling in a preclinical

127 y encapsulation in molecular containers from the first reports of covalent containers described by Cr

128 and H1) and group 2 (H3) influenza viruses, the first report of cross-group protection.

129 to Rico populations in 2007, coincident with the first reports of damage to TC1507 corn.

130 Since the first report of DCC applied to the discovery of bind

131 This is the first report of decreased dorsal and ventral striata

132 To the best of our knowledge, this is the first report of deoxynivalenol-3-glucoside in wheat

133 This is the first report of detailed analysis of the chemical co

134 This is the first report of detection and expansion of potent mH

135 This is the first report of DMHF in 'Hayward' kiwifruit.

136 This is the first report of DNA methylation in a Rosaceae specie

137 To our knowledge, this is the first report of E. ewingii infection of human bone m

138 To our knowledge, this is the first report of E3 ubiquitin ligase phosphorylation

139 ndependent role in cell death control and is the first report of ectodomain shedding in plants.

140 This is the first report of elaiophylins, actinomycin X0beta and

141 The data described here represent the first report of electrochemical behavior of a sulfur

142 To our knowledge, this is the first report of elevated CSF cytokines in a patient

143 To our knowledge, this is the first report of endothelial LARG regulating leukocyt

144 This is the first report of environmental surveillance for MeV,

145 This is the first report of Epsilonretrovirus Gag localizing to

146 To the best of our knowledge, this is the first report of excessive pericyte coverage in dista

147 To our knowledge, this is the first report of experimentally measured internal upc

148 This is the first report of faceted electrochemical growth that

149 beach water quality, and this appears to be the first report of falconry in the context of TMDL impl

150 ulation-based study of rotavirus in cats and the first report of feline G6P[9], which questions the p

151 As the first report of fibrosis-associated molecules altere

152 g has generated enormous interest, following the first report of generation of induced pluripotent st

153 This is the first report of genetic and clinical analysis of CDS

154 ultiple glycoforms are identified, including the first report of glycosylated insulin-B chain and ins

155 We demonstrate the first report of graphene paper functionalized with f

156 This is the first report of gut bacterial flora of wild-caught P

157 We present to our knowledge the first report of hair repigmentation owing to anti-PD

158 This study is the first report of high-throughput transcriptional prof

159 ering plant pollination systems and provides the first report of highly specialized bellows organs fo

160 To our knowledge, this is the first report of human lineage-negative (Lin(-)) CD34

161 aldsonii and Legionella sp. D5382 are likely the first reports of human infection with these organism

162 l role for PepN in antibiotic maturation and the first report of hydrolysis of beta amide linkage by

163 This is the first report of (i) a ZIKV vaccine based on the NS1

164 In addition, this is the first report of identification of gene transcription

165 This is the first report of identification of the potential IFN

166 This is the first report of idiopathic ventricular fibrillation

167 To our knowledge, this is the first report of impaired plasmid maintenance caused

168 This study represents the first report of in vitro FUT8-catalyzed core fucosyl

169 To our knowledge, this is the first report of in vivo chemopreventive effect of SP

170 To our knowledge, this is the first report of in vivo imaging of infection with an

171 in families with mutations in FLNA, this is the first report of individuals being affected by Ebstei

172 Here we present the first report of infinite-range interactions between

173 This work is the first report of inhibition studies on UGM from eukar

174 best of our knowledge, this study represents the first report of intrinsic developmental differences

175 To our knowledge, this is the first report of isolation of this rapidly growing my

176 This is the first report of KIDINS220 variants causing a human d

177 This is the first report of killing of established adult schisto

178 This represents the first report of laserspray ionization vacuum (LSIV)

179 This is the first report of latent CyHV-3 in B cells and identif

180 This is the first report of lethal disease caused by SNV in an a

181 man isolate in immunocompromised mice and is the first report of lethal infection by a nonadapted cli

182 This is the first report of linseed-induced allergy in Japan.

183 Here, the first report of low-voltage-controlled molecular rel

184 This is the first report of MAP2K1 mutations in LCH that occur i

185 (HS-HoloFt) has been widely studied, this is the first report of mass spectrometry (MS) analysis of t

186 This is the first report of measles transmission from a twice-va

187 and microscopy data, these results represent the first report of metallic behavior and permanent poro

188 This represents the first report of MRI-guided myocardial chemoablation,

189 As the first report of multifaceted supramolecular assembli

190 Together with the first report of N-N coupling between NO molecules in

191 This is the first report of neonatal adiposity as a predictor of

192 e best of our knowledge, these compounds are the first reports of non-thymidine-like inhibitors of Mt

193 To our knowledge, this is the first report of nucleolar functions for NSs within t

194 This is the first report of overdominance in the nicotinic syste

195 d-water feeding in Bryde's whales represents the first report of passive feeding in baleen whales, wh

196 This is the first report of patient mutations causing disease by

197 To our knowledge, this is the first report of PCI with BRSs in a child.

198 To our knowledge, this is the first report of peptide antagonist for prokaryotic N

199 The work herein represents the first report of pEtN addition to Pseudomonas aerugin

200 This is the first report of PFPIAs in fish, dolphin, and bird pl

201 To the best of our knowledge, this is the first report of phage therapy in a mouse model again

202 This is the first report of PMGF in GR common waterhemp and the

203 put routine quality control of GPEs, this is the first report of PPs content for Bonarda and Aspirant

204 Our results constitute the first report of presentation order effects in the Ep

205 ilateral NewColorIris(R) implants, including the first report of pressure-induced stromal keratopathy

206 This is the first report of prion infectivity within the cervid

207 To our knowledge, this is the first report of PRKCA fusions in melanocytic neoplas

208 This is the first report of propane and butane sorption isotherm

209 genome of Polytoma uvella: to our knowledge, the first report of ptDNA from a nonphotosynthetic chlam

210 e of N. thailandica in the United States and the first report of pulmonary infection by this pathogen

211 This is the first report of pyroptosis in airway epithelia infec

212 g across the WIPP site intensified following the first reports of radiation detection underground to

213 We present here the first report of recurrent peripheral corneal infiltr

214 This is the first report of reduction of insect reproductive fit

215 This is the first report of RH-temperature phase diagrams of glu

216 This is the first report of risk factors for and characteristics

217 To our knowledge, this is the first report of robust BNF in major cereal crops.

218 This is the first report of RSV ON1 genotype in the United State

219 la and S. eubayanus in New Zealand, which is the first report of S. arboricola outside Far East Asia,

220 This is the first report of SAA3 as a cause of amyloidosis and o

221 To our knowledge this is the first report of scaling laws of critical slowing dow

222 This is the first report of selective, nanomolar inhibitors of T

223 This is the first report of serial integrated and combined metab

224 This is the first report of serum antibodies to surface D2R and

225 est pCO2 levels reported to date, as well as the first report of significantly wider daily otolith gr

226 To our knowledge, this is the first report of simultaneous detection of HSV-1 and

227 Ours is the first report of sirolimus-associated PRES in the set

228 Here, we provide the first report of somatodendritic release of CCK in th

229 This is the first report of spatiotemporal opposing effects of a

230 To our knowledge, this is also the first report of Streptococcus anginosus constellatus

231 To our knowledge, this is the first report of structural hippocampal changes with

232 To our knowledge this is the first report of structures of this type.

233 This is the first report of styrylflavylium cations with photois

234 It should be the first report of such a case.

235 This is the first report of such a function for a cytokine.

236 To our knowledge, this is the first report of such a growth mode using a fs laser.

237 lignin composed of 5-hydroxyguaiacyl units, the first report of such a polymer that occurs naturally

238 This is the first report of TA receptor function in a native tis

239 This is the first report of tandem target gene amplification con

240 Overall, as the first report of targeted gene deletion mutant in U.

241 echanisms in ALS, FTLD, and AxD, and this is the first report of TDP-43 involvement in a neurological

242 We describe the first report of temporally related cases of Bordetel

243 This is the first report of tenuazonic acid in Brazilian sorghum

244 To our knowledge, this is the first report of the absence of a functional xanthoph

245 This is the first report of the application of a (12)C beam for

246 This is the first report of the association of human HLA types a

247 This is the first report of the characterizing disease progressi

248 To our knowledge, this is the first report of the contemporary fraction of DEHP is

249 To our knowledge, this is the first report of the critical contribution of neutrop

250 To our knowledge, this is the first report of the crystal structure of the alpha-h

251 To our knowledge, this is the first report of the development of antibodies to a h

252 To our knowledge, this is the first report of the differential detection of B. glo

253 Collectively, this is the first report of the dynamic interactions of neutroph

254 The first report of the effect of hibernation on the gut

255 In summary, this work represents the first report of the functional outcome of serine/thr

256 This is the first report of the genotype E SFTSV strains in main

257 To our best knowledge, this is the first report of the identification and quantificatio

258 This is the first report of the identification of two major vari

259 This is the first report of the improvement of levan production

260 This study is the first report of the interconversion of an end-on per

261 This is the first report of the mechanisms underlying glucose-in

262 To our knowledge, this is the first report of the misidentification of viruses in

263 This is the first report of the occurrence of fumonisin B1 in co

264 To our knowledge, this is the first report of the participation of miR-33 in LC-PU

265 This is the first report of the potential peripheral mechanisms

266 Here, the authors provide the first report of the presence of compromised myocardi

267 This is the first report of the prevalence of oxygenase genes th

268 This is the first report of the production of lysozyme inhibitor

269 This work is the first report of the structure of CoA bound to an ald

270 This is the first report of the synthesis of isomelezitose by a

271 This is the first report of the synthesis of spiromorpholinotetr

272 To our knowledge, this is the first report of the systemic administration of mRNA

273 This is the first report of the use of multicomponent reactions

274 We present the first report of the use of phage display to identify

275 This is the first report of the use of transcriptome-wide sequen

276 This study is the first report of the V410L mutation in mosquitoes.

277 These are the first reports of the direct detection of H. capsulat

278 n vitro analytic tool, in the past few years the first reports of the feasibility of in vivo imaging

279 s) has been an important open question since the first reports of the strong modulation of electrical

280 K1 in mitochondrial dynamics and constitutes the first report of this gene in association with a seve

281 This case likely represents the first report of this leprosy form and its agent in t

282 ter its original identification in Spain and the first report of this opportunistic pathogen in the A

283 sessed inverse agonist activity at the MC5R, the first report of this pharmacology.

284 iterature, our finding, to our knowledge, is the first report of this phenomenon in humans and the fi

285 This is the first report of this species in clinical samples.

286 Although the first reports of this reaction appeared in the liter

287 This is the first report of three enzymatically active neurotoxi

288 This study is also the first report of transcriptional co-regulation existi

289 This is the first report of transcriptome and chloroplast genome

290 This is the first report of transgenic overexpression of CD39 in

291 This is the first report of treatment resistance as a result of

292 In the case of CEP164, this is the first report of two siblings with a BBS-like syndrom

293 Although DBS might be ideal for POC, this is the first report of using an SPR biosensor for measuring

294 This is the first report of using NaBH4 for powering micromotors

295 To our knowledge, this work is the first report of using PEG-DET for protein delivery a