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1 -up study, which was performed 6 weeks after the first study.
2                                           In the first study, 889 untreated anti-HCV-seropositive pat
3                                      This is the first study about removal of lead (Pb(II)) from ener
4                                      This is the first study addressing the function of CCP5 in mamma
5                                      This is the first study addressing the genetic determinants of N
6                                   We present the first study and comparison of the performance of mag
7                              Here we present the first study applying this approach to forest tree co
8                                              The first study arm consisted of 8 pairs of eyes in whic
9                                      This is the first study characterising the genetic structure of
10                       In conclusion, this is the first study characterizing the in vivo functions of
11                       The median lifespan of the first study circuit in each patient was 39.2 hours (
12                               This is one of the first studies clearly demonstrating that macroevolut
13                                 This is also the first study combining IGS sequencing data with RFLP
14                                      This is the first study combining omics technologies to describe
15                                           As the first study concentrated in the transposition activi
16                                      This is the first study correlating increased expression of neur
17                                      This is the first study dealing with this matter under field con
18                                      This is the first study demonstrating a direct comparison of EET
19                    To our knowledge, this is the first study demonstrating a transcriptional modulati
20        To the best of our knowledge, this is the first study demonstrating how N. fowleri can persist
21                    To our knowledge, this is the first study demonstrating inflammation within the ne
22                                      This is the first study demonstrating recognition of archaeal vi
23        To the best of our knowledge, this is the first study demonstrating Se transference during met
24                                      This is the first study demonstrating that the APOE*E2 allele mo
25        To the best of our knowledge, this is the first study demonstrating that the diversity of diff
26                                      This is the first study demonstrating that the presence of rotor
27                                      This is the first study demonstrating that vaccination of males
28                    To our knowledge, this is the first study demonstrating the association between mu
29        To the best of our knowledge, this is the first study demonstrating the success and feasibilit
30                    To our knowledge, this is the first study depicting a protective function of MGL1
31                                      This is the first study describing a beneficial role of the comm
32                                      This is the first study describing ToF-SIMS imaging for probing
33                                 We conducted the first study designed and powered to investigate the
34                     To our knowledge this is the first study documenting direct nicotinic modulation
35                                      This is the first study documenting the presence of BuV and TuV
36                                      We gave the first study dose of OPV at age 6 weeks.
37 ry outcome was lactate levels 24 hours after the first study dose.
38 nal secretion.SIGNIFICANCE STATEMENT This is the first study examining the mechanism of mutant huntin
39                                This paper is the first study focused on the innovative application of
40                                           In the first study, global transcriptomic analysis indicate
41                                           In the first study, Huls et al. show an association between
42 men and 6 men) participated in 2 studies: in the first study, human radiation dosimetry and biodistri
43                                      This is the first study illustrating a molecular mechanism linki
44 t role from AtMPK9 To our knowledge, this is the first study implicating a function for a TDY MAPK in
45                         Therefore, we report the first studies in humans demonstrating that pharmacol
46                                      This is the first study in children with steroid-resistant NS wh
47                                      This is the first study in humans to identify endothelium-depend
48                                      This is the first study in S. aureus that identifies a DNA-bindi
49                                      This is the first study in which CML formation was linked to ava
50                                      This is the first study in which mycotoxins and other microbial
51                    To our knowledge, this is the first study in which the time course of hospitalizat
52           To the authors' knowledge, this is the first study in which the uptake and time-dependent a
53                                      This is the first study introducing an Aspergillus strain for be
54                                      This is the first study investigating patients' IgG glycosylatio
55                                      This is the first study investigating symptoms that have proven
56   To the best of our knowledge, this is also the first study investigating the effect of AMPs on airw
57                                      This is the first study linking maternal serum concentrations of
58                                           In the first study, LRRK2 mutation carriers with or without
59                                        Since the first studies of BMT in the late 1980s, a number of
60                            Here we conducted the first study of 22q11.2 gene dosage effects on brain
61                                   We present the first study of a novel, more sensitive method for th
62                                  UNICORN was the first study of an off-label protocol using whole blo
63                                      This is the first study of Chlamydia-infected cells showing the
64                     This research represents the first study of coupled geochemistry and microbiology
65 e Caenorhabditis elegans, we have undertaken the first study of heme transport in Brugia malayi, a ca
66                                      This is the first study of human listeners with normal hearing t
67                                Therefore, in the first study of it is kind, we use measured populatio
68                                      This is the first study of its kind demonstrating that donor age
69                              Here we present the first study of parahydrogen-induced polarization NMR
70                                      This is the first study of POT guided by intravascular ultrasoun
71            The proposed assay was applied to the first study of sEVs secretion from TK6 cells culture
72                                      This is the first study of the biological effects of LCs on pulm
73                              Here we provide the first study of the human head using anatomical netwo
74 Bs in Residences and Schools), which will be the first study of the long term health effects of the l
75                               Here we report the first study of the neutron radiation tolerance of tw
76                             Herein we report the first study of the oxygen reduction reaction (ORR) c
77           To the authors' knowledge, this is the first study of the relationship between a maternal s
78                                      This is the first study of the stratigraphic variation of alkyl
79                                      This is the first study of the use of MOFs for biofouling contro
80                              Here, we report the first study of thermal transport in SACs, a critical
81                                      This is the first study on FBS showing this behaviour in the ful
82                                Here, we show the first study on membrane-associated pHLIP using solid
83                             Here, we present the first study on oxidative damage of human telomere G-
84                    To our knowledge, this is the first study on rosacea to formally define genetic an
85                                      This is the first study on the hyperedge cardinality in hypernet
86                                      This is the first study on the nanoencapsulation of Danube fish
87        To the best of our knowledge, this is the first study predicting gammai for bisolute adsorptio
88                                      This is the first study presenting wide range of elements in gre
89                                      This is the first study providing evidence for Zika virus infect
90                                      This is the first study providing evidence that TAVI results in
91                                      This is the first study providing proof-of-concept that NRF2 act
92        To the best of our knowledge, this is the first study regarding detailed investigation of hepa
93                                      This is the first study reporting a qLAMP based-method for the d
94                                      This is the first study reporting excretion of sTAM receptors in
95                    To our knowledge, this is the first study reporting IUGR-induced programmed adult
96                                      This is the first study reporting LG volumes in BPES, describing
97                                      This is the first study reporting that cardiac enzymes and infla
98                                      This is the first study reporting the potential prebiotic effect
99 ented polyphosphate delivery strategy enable the first studies required to understand InsP7 signallin
100                      Furthermore, we present the first study revealing AFP glycopeptide signatures of
101                                      This is the first study showing that ADR variants are susceptibi
102  6.50 x 10(-8) for rs4950(.) This represents the first study showing that CHRNB3/A6 are highly associ
103                       In conclusion, this is the first study showing the feasibility of noninvasive i
104                                      This is the first study showing, in real time, Ca(2+) signals pr
105                                           In the first study, sixteen beef cattle were implanted with
106                    To our knowledge, this is the first study suggesting that PFAS are associated with
107                    To our knowledge, this is the first study supporting the pro-proliferative functio
108                    To our knowledge, this is the first study that associated levels of CHIKV load wit
109                                      This is the first study that demonstrates that arginine vasopres
110        To the best of our knowledge, this is the first study that describes the use and reaction mech
111                    To our knowledge, this is the first study that documents significant differences i
112                                      This is the first study that evaluates ERC-related infectious co
113                    To our knowledge, this is the first study that evaluates the functional and clinic
114                                      This is the first study that evaluates the toasting effect on wi
115                                      This is the first study that has systematically investigated how
116                              Here we present the first study that integrates protein ChIP-seq and Hi-
117                                    We report the first study that investigates the neural mechanisms
118                    To our knowledge, this is the first study that provides the presence of CWA relate
119                                      This is the first study that showed an association between key p
120                                      This is the first study that such analysis has been reported and
121                                 This is also the first study that systematically investigates dendrit
122               To our best knowledge, this is the first study that uses whole-exome sequencing for the
123                    To our knowledge, this is the first study that utilizes both machine learning and
124                                          For the first study, timed-pregnant B6C3F1 mice were exposed
125      To the best of our knowledge, these are the first studies to demonstrate complement activation b
126                               This is one of the first studies to demonstrate that these risk behavio
127                                    These are the first studies to examine the acquisition of heroin S
128             To our knowledge, this is one of the first studies to experimentally demonstrate interact
129                               This is one of the first studies to find diet-mediated tolerance.
130 tocols.SIGNIFICANCE STATEMENT This is one of the first studies to use a repeated-measures imaging pro
131                                      This is the first study to analyse community DNA (targeting meio
132                                     This was the first study to analyze multiple HSV-2 sequences, and
133                                      This is the first study to apply a Cumulative Exergy Extraction
134                    To our knowledge, this is the first study to apply machine learning models with EH
135        To the best of our knowledge, this is the first study to assay these compounds for their radio
136                                      This is the first study to assess inflammatory markers related t
137                                      This is the first study to assess inflorescence phenotypes of fi
138                                      This is the first study to assess liposomes as a delivery vehicl
139                                      This is the first study to assess the perfusion, injury, as meas
140                                      This is the first study to associate the timing and directionali
141                                  We describe the first study to characterise accumulated consequences
142                                      This is the first study to characterize sTim-3 in human plasma,
143                                      This is the first study to characterize the adsorption of POEA t
144                                      This is the first study to characterize the functional connectiv
145                                      This is the first study to combine such a large number of neuron
146                    To our knowledge, this is the first study to combine these aspects with the result
147                                      This is the first study to compare genome-wide DNA methylation p
148                                      This is the first study to comprehensively analyze m(6)A pattern
149                                      This is the first study to conduct precise 3D molecular mapping
150                    To our knowledge, this is the first study to couple unbiased measures of microenvi
151                    To our knowledge, this is the first study to date of place of birth and incident d
152                                      This is the first study to date to examine volumetric alteration
153                    To our knowledge, this is the first study to define the incidence of preoperative
154                                      This is the first study to demonstrate a cognitive role related
155                                      This is the first study to demonstrate associations between the
156                                      This is the first study to demonstrate decreased fatty acid desa
157                                      This is the first study to demonstrate direct lysosomal targetin
158                      We believe that this is the first study to demonstrate how lighting may create r
159                                      This is the first study to demonstrate prospective changes in gu
160                           We believe this is the first study to demonstrate significant genetic overl
161                            Moreover, this is the first study to demonstrate similar findings over a s
162                                      This is the first study to demonstrate that abnormal functional
163                          In summary, this is the first study to demonstrate that BDD and MDD with com
164                                      This is the first study to demonstrate that binding of ProTx-II
165                                      This is the first study to demonstrate that genetic inhibition o
166                                      This is the first study to demonstrate that hCoV-HKU1 uses certa
167      In addition, this is, to our knowledge, the first study to demonstrate that infants 6-9 mo of ag
168                                      This is the first study to demonstrate that LAIV elicits humoral
169                                      This is the first study to demonstrate that microsatellite marke
170                                      This is the first study to demonstrate that N(pro) is able to bi
171                    To our knowledge, this is the first study to demonstrate that SAA1 is induced in t
172                                      This is the first study to demonstrate that schizophrenia liabil
173                    To our knowledge, this is the first study to demonstrate that skeletal muscle atro
174  the best of the authors' knowledge, this is the first study to demonstrate that the increased oxidat
175                                      This is the first study to demonstrate that trace fear condition
176                    To our knowledge, this is the first study to demonstrate the clinical utility of p
177        To the best of our knowledge, this is the first study to demonstrate the crucial role of react
178                                      This is the first study to demonstrate the extracellular proteol
179                                      This is the first study to demonstrate the pathophysiological ef
180                    To our knowledge, this is the first study to demonstrate the specificity of such m
181                                      This is the first study to describe in detail the fate of microp
182                                      This is the first study to detect an acute DNA damage response i
183                                        It is the first study to detect increasing levels of endotoxem
184                                      This is the first study to determine the stability of reference
185 o the best knowledge of the authors, this is the first study to develop a novel rat model of polymicr
186                       In conclusion, this is the first study to develop and show that receptor-target
187 al and psychosocial characteristics, this is the first study to differentiate them biologically on HP
188 iatal brain areas in both disorders, this is the first study to directly compare the glutamate concen
189                                           In the first study to directly measure C(a-v)o2 throughout
190 such increases in dopamine post-DBS, this is the first study to do so using MS methodologies.
191                    To our knowledge, this is the first study to document an association of prenatal m
192                                      This is the first study to document prospectively a 42% conversi
193                                      This is the first study to document the occurrence and migration
194                                      This is the first study to employ in planta RNAi approach to tar
195                                      This is the first study to evaluate elamipretide in heart failur
196                                      This is the first study to evaluate pulmonary critical care fell
197                                      This is the first study to evaluate the association of T2DM with
198                                      This is the first study to evaluate the effects of DREADD-mediat
199                                      This is the first study to evaluate TMS-associated changes in co
200                                      This is the first study to evaluate tolerance of nifurtimox in U
201                                      This is the first study to examine IGR IRES translation in its n
202                    To our knowledge, this is the first study to examine the associations between sub-
203 of altered arterial elastin content, this is the first study to examine the cause-and-effect relation
204  the best of the authors' knowledge, this is the first study to examine the combined effect of sustai
205                                      This is the first study to examine the effects of ECEs at the si
206                                      This is the first study to examine the efficacy of a syrbactin i
207                    To our knowledge, this is the first study to examine the relationship between long
208                                      This is the first study to examine whole-brain network activity
209                             Here, we present the first study to explicitly evaluate the role of micro
210                    To our knowledge, this is the first study to explore coping as a multifaceted cons
211                                      This is the first study to explore the role of Scx in cortical b
212                                      This is the first study to explore the therapeutic potential of
213                                      This is the first study to explore training-induced changes in t
214                                      This is the first study to find a reduction in intensity of end-
215                                      This is the first study to find a temporal association between l
216                                      This is the first study to globally assess the human skin transc
217                                      This is the first study to identify a motif recognized by AR-con
218                                      Ours is the first study to identify a structural brain marker-vo
219                                      This is the first study to identify a surgeon volume threshold (
220                                      This is the first study to identify a surgeon volume threshold (
221                                      This is the first study to identify computational impairments du
222                                      This is the first study to identify cross neutralizing scFv mono
223                    To our knowledge, this is the first study to identify endogenous and viral MHC cla
224                                      This is the first study to identify PTEN as a potential downstre
225                                      This is the first study to identify that increased circulating P
226                                      This is the first study to identify the mechanism by which diffe
227                    To our knowledge, this is the first study to indicate that frequent fish consumpti
228                                 This is also the first study to investigate and show an association o
229                                      This is the first study to investigate ex vivo FCM application i
230                                      This is the first study to investigate immunogenetic variations
231                    To our knowledge, this is the first study to investigate the association between A
232 n To the best of our knowledge, CONKO-005 is the first study to investigate the combination of chemot
233                    To our knowledge, this is the first study to investigate the long-term association
234                                      This is the first study to investigate the synergistic effect of
235                                      This is the first study to investigate the usefulness of the VHS
236                                      This is the first study to investigate thrombocytopenia within t
237                    To our knowledge, this is the first study to investigate whether rates of eating d
238                                      This is the first study to link the effects of pregnant women's
239                                      This is the first study to link the innate immune system to mito
240                                      This is the first study to look at the in vivo changes in the br
241                                      This is the first study to our knowledge to calibrate a model of
242                                 This work is the first study to present an integrated view of the eff
243                    To our knowledge, this is the first study to propose an integrated global set of s
244                    To our knowledge, this is the first study to provide a mechanism for the intrinsic
245                    To our knowledge, this is the first study to provide evidence of the absence of an
246                                      This is the first study to provide evidence that donor Cav1 geno
247                                      This is the first study to provide the intimate structural basis
248                    To our knowledge, this is the first study to quantify the consequences of climate
249                                      This is the first study to quantify the long-term durability of
250                             Here, we present the first study to quantify the terrestrial locomotor mo
251                             Here, we present the first study to quantitatively profile TK activity in
252                    To our knowledge, this is the first study to reduce search engine data bias levels
253                                      This is the first study to report a long-term chronosequence of
254                                      This is the first study to report an association between exposur
255                    To our knowledge, this is the first study to report an association of both BP-3 an
256                                      This is the first study to report aPTT-related genetic variants
257 dia with polymorphism at FBX011, but this is the first study to report association with the locus TGI
258                                      This is the first study to report identification of major coenzy
259                                      This is the first study to report structure-activity relationshi
260                                      This is the first study to report that mixtures resulting from t
261                                      This is the first study to report the highly conserved parvoviru
262         This is to the best of our knowledge the first study to report within an RCT a differential c
263           Conclusions and Relevance: This is the first study to reveal an association between intrins
264                                      This is the first study to reveal relationships between ventrome
265                                      This is the first study to reveal that TATA boxes and poly (A) t
266                    To our knowledge, this is the first study to show a significant enhancement of hyg
267 ed (ASL) magnetic resonance imaging, this is the first study to show regional reductions in cerebral
268                                      This is the first study to show that attention to social feature
269                    To our knowledge, this is the first study to show that cytosolic receptors recogni
270               In addition, we have conducted the first study to show that integrating the additional
271                                      This is the first study to show that longitudinal trajectories o
272                                      This is the first study to show that metals can be taken up by t
273                    To our knowledge, this is the first study to show that PI(4,5)P2 acyl chains diffe
274                            Moreover, this is the first study to show that this interaction plays an i
275                      INTERPRETATION: CALM is the first study to show that timely escalation with an a
276                                      This is the first study to show the effects of direct violence e
277                                 This is also the first study to show the effects of in vivo miRNA inh
278                                      This is the first study to show the link between pediatric catar
279                           We believe this is the first study to suggest that an extracellular water i
280                                      This is the first study to suggest that congenital CMV infection
281                                      This is the first study to suggest that even if distress appears
282                              Here we present the first study to systematically alter the degree of so
283                                      This is the first study to systematically investigate ICP0 eleme
284                                      This is the first study to test for parental age effects on offs
285                    To our knowledge, this is the first study to uncover a bacterial metabolite with t
286                                      This is the first study to use 3D photogrammetry to assess fine-
287                                      This is the first study to use chemometric methods to differenti
288                                      This is the first study to use high-throughput sequencing of imm
289                                      This is the first study to use iPSC-derived human neurons to mod
290                       This report summarizes the first study to use MALDI-IMS to analyze drug penetra
291                                      This is the first study to utilise human cerebellum fixed in par
292                                      This is the first study to validate and calibrate current-flow m
293                                           As the first study (to our knowledge) to link stress to tel
294                                      This is the first study, to our knowledge, of the prevalence of
295                                      This is the first study, to our knowledge, to report the immunoh
296                                      This is the first study, to our knowledge, to systematically exp
297                                      This is the first study using an integrated approach to understa
298                                      This is the first study using MIEs in vivo to measure rapid chan
299                               Here we report the first study utilizing targeted next-generation seque
300                           But here we report the first study which correlates differences in the elec

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