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1 omics, and public policy, and emphasize that the importance of a balanced diet may extend beyond the
2 nus and the CLK PAS-B domain and demonstrate the importance of a BMAL1 TAD-independent mechanism for
3                                      Despite the importance of a cellular population of tubulin dimer
4 res seen in the crystal structure, including the importance of a hydrogen bond between Thr-238 and th
5 y in solid-state organic D-A blends and show the importance of a reduced relaxation energy, which we
6                         This concept implies the importance of a three-dimensional (3D) culture model
7            Moreover, our study shed light on the importance of AAAs and might provide new ideas for i
8                   These findings demonstrate the importance of aberrant afferent input in the mainten
9                                   We propose the importance of accessing CT states for photoredox cat
10 aviour, and regulatory functions emphasizing the importance of accounting for environment in genetic
11                    These findings underscore the importance of achieving widespread delivery of thera
12 dherence was worst in children, highlighting the importance of advice to caregivers.
13                   Recent evidence highlights the importance of alterations in mechanical properties o
14 ) and polymorphonuclear neutrophils and show the importance of an antibody/effector cell interaction
15 ial for integrin co-activation and highlight the importance of an atypical architecture of the K2 FER
16 ity and Ecosystem Services (IPBES) recognize the importance of an increasingly global, quantitative a
17                      These studies highlight the importance of analyzing metabolism in effector lymph
18  head direction cells and the realization of the importance of angular and linear movement-integratio
19 ever, a series of recent studies demonstrate the importance of another cell type, astrocytes, for bio
20  adverse effect of the PIP/TAZO shortage and the importance of antibiotic stewardship when mitigating
21 s with humans and nonhuman primates revealed the importance of antibody responses in preventing HIV-1
22           In vitro studies have demonstrated the importance of apolipoproteins in HCV secretion and i
23                        Our results emphasize the importance of APP in AD and should stimulate new stu
24                       Our results illustrate the importance of appropriate drought measures and, as a
25 to the basis for ASO-FUS binding illustrated the importance of ASO backbone and hydrophobic 2' sugar
26 ntally realistic conditions, and illustrated the importance of assessing exposure through all media i
27                                              The importance of assessing the contribution of the prec
28 s to explain biochemical and genetic data on the importance of B-subunit integrity in replisome funct
29 n this short review, we particularly discuss the importance of benchmarking stem cell-derived hepatoc
30 significant differences in IC among centers, the importance of biliary strictures as a risk factor fo
31                                              The importance of biodiversity in supporting ecosystem f
32                      This finding highlights the importance of biotic interactions in shaping geograp
33                                        Given the importance of biting midges as vectors, a key area o
34                        This study emphasizes the importance of boreal forest humus soils for Hg stora
35 s may help epidemiologists better understand the importance of both online and offline networks for p
36 regarding their elevated risks of cancer and the importance of cancer screening.
37                       The findings underline the importance of careful psychopathological assessment
38             Collectively, our data highlight the importance of CDCC and CDCP in monoclonal-antibody f
39                                              The importance of cell death in brain development has lo
40                      These results highlight the importance of choosing cells lacking endogenous MA c
41                     These findings highlight the importance of chromatin states and transcriptional p
42 avian-specific traits, and further highlight the importance of cis-regulatory rewiring during macroev
43                                              The importance of climate-soil interactions to Se distri
44                      These methods highlight the importance of computational techniques in fMRI analy
45 tem variability relationships and highlights the importance of conserving regional species pools to h
46       We use our data and results to discuss the importance of considering changes in tidal range whi
47                   These findings demonstrate the importance of considering differences between experi
48        Taken together, these results suggest the importance of considering gender as a biological var
49                      Our results demonstrate the importance of considering multiple and conflicting s
50 emperature dependence of GPP, and highlights the importance of considering physiological, ecological
51                              Our study shows the importance of considering spatially structured dynam
52                     This analysis highlights the importance of considering the legacy of past ecosyst
53                         Our study highlights the importance of considering the packing when analyzing
54                    These findings underscore the importance of considering the potentially different
55                        Our results emphasize the importance of continuing surveillance of sexual beha
56 anism of the phase transitions, highlighting the importance of cooperative multiscale processes.
57 in shallow CO2-rich hydrothermal systems and the importance of coupling highly specific process indic
58                 Our data therefore highlight the importance of CpG-sites and transcriptional activity
59 This expanded analysis further characterizes the importance of CTC-based AR-V7 mRNA detection in pred
60 sm; pharmacological and genetic data suggest the importance of delta-opioid receptors.
61                           Our data emphasize the importance of dental disease and tooth extraction in
62 a median survival of 14 months, underscoring the importance of developing effective new therapeutic s
63 e used structural equation modelling to test the importance of direct and indirect (via floral resour
64           This essay offers a perspective on the importance of diversity in our educational instituti
65                     These results underscore the importance of documenting head injuries even within
66 ng density was never recovered, highlighting the importance of early intervention with A1PI treatment
67 of movement on estimator accuracy emphasizes the importance of effective post-hoc calculation of area
68 mine the generalizability of this effect and the importance of encouraging older adults to engage in
69 ons as a means of lowering kappaL , but also the importance of engineering both thermal and electroni
70 yll a Correlations with temperature point to the importance of environmental selection in structuring
71 ial cell receptor-blind viruses demonstrated the importance of epithelial cell infection for clinical
72                      Our results demonstrate the importance of ERK/MAPK signaling in governing the mo
73                  In this review, we evaluate the importance of ERs in bone metastasis and discuss new
74                       This work demonstrates the importance of evaluating removal of contaminants of
75          Recent discoveries have highlighted the importance of fatty acids, in addition to sugars, ac
76                    These studies demonstrate the importance of ferritin for the vectorial transfer of
77 t ways ferulic acid can be present in maize, the importance of ferulic acid derivatives and the metho
78               Therefore, our data underscore the importance of finely regulated endosomal traffic in
79  model (an elastic network model) highlights the importance of flexibility in the entrance region.
80 ic changes on distribution shifts and stress the importance of framing climate expectations in refere
81 itivity to activation via PGE2, underscoring the importance of FRCs in shaping the suppressive milieu
82    These opposing emissions trends emphasize the importance of fully functional DPFs.
83 multiple bacteria settlement cues highlights the importance of further studies into the role of bacte
84 of AID for structured substrates and uncover the importance of G4 recognition and oligomerization of
85 of GA4 in the distinct lifestyle of Xoc, and the importance of GA to both fungal and bacterial pathog
86 vel DNMT3B cis-acting QTL variant highlights the importance of genetically influenced regulation in b
87             Overall, these results highlight the importance of genomic draft, in which strong linkage
88                               By documenting the importance of geographies of synchrony, advancing co
89 "fuzzy" complex, and our results demonstrate the importance of heterogeneous complex formation in tau
90       Limitations of calculation methods and the importance of high quality food composition data are
91 ity improvement initiatives should highlight the importance of high-quality color Doppler imaging and
92 nks between the two, few studies have tested the importance of hippocampal-OFC interactions.
93  analyses of CRC tissues further corroborate the importance of histone H4K16 acetylation in CRC.
94 is for microbial adaptability and underscore the importance of hosts as selective agents that shape e
95 d N and P inputs, respectively, underscoring the importance of household actions in influencing urban
96 ly been unreported, even though evidence for the importance of HSV-2 antigen-specific CD8 T cells is
97                                Understanding the importance of human activities on TOC changes requir
98 , success needs institutional recognition of the importance of human behavior), good data are not eno
99 es reported for IAPP fibrils and demonstrate the importance of hydrogen bonding and hydrophobic inter
100  of microrefugia insufficiently accounts for the importance of hydrologic processes and changing wate
101 nd add to a growing literature demonstrating the importance of identifying normative trajectories of
102                      Our findings underscore the importance of IL-10R signaling in preventing T-cell-
103 obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protect
104  samples still exceeded 10 mug/L, reflecting the importance of implementing full LSL replacement and
105                     These findings highlight the importance of improving awareness of HIV status and
106 0(+ve) B cells to autoimmunity, highlighting the importance of improving the understanding of the reg
107 nts in deteriorating drag reduction and thus the importance of including surfactant stresses in SHS m
108                             Further, we show the importance of incorporating biogeographic and phylog
109 asympathetic tone respectively, highlighting the importance of individual neural and autonomic differ
110  reporter system to quantitatively determine the importance of individual receptors in HCV cell-free
111                        This study highlights the importance of innate effector cells in establishing
112                                        Given the importance of insulin and its related peptide hormon
113                      Our research highlights the importance of integrating information on genetic var
114 sive interactions in the gas phase properly, the importance of inter- and intramolecular dispersion i
115                        These findings reveal the importance of intracellular transport in steady-stat
116                            Our findings show the importance of investigating non-coding regulatory va
117                                      Despite the importance of ions in fungal decay mechanisms, the s
118 ence strategy, but with geography, revealing the importance of isolation-by-distance dynamics in the
119                        Our results highlight the importance of kinesin-3 based axonal transport in sy
120  and DR-1 transgenic mice were used to study the importance of LAIR-1 in autoimmune arthritis.
121 integrins function at the level of adhesion, the importance of lectins remains unknown.
122                         Our study highlights the importance of lifelong monitoring of cardiovascular
123                          We used it to probe the importance of lipid peroxidation in progression of N
124 counts of pandemic cholera with data to show the importance of local lineages, presenting an integrat
125          Collectively, this study reinforces the importance of LrgAB to the S. mutans stress response
126 eas in Central Europe, little is known about the importance of LTP sensitization.
127                      This finding highlights the importance of macrocyclization in combination with r
128 m under coffee roasting conditions, implying the importance of Maillard reactions in CO2 formation.
129                        Our results highlight the importance of maintaining a diverse portfolio of urb
130  the major unmet need in this population and the importance of maintaining or improving quality of li
131                         This work points out the importance of matching the charge transport layers i
132 m signatures are not intuitive, exemplifying the importance of mathematical modelling approaches.
133 onal studies, our findings further emphasize the importance of measures to reduce the global epidemic
134                                              The importance of mechanical forces in influencing cell
135                                              The importance of metabolism in macrophage function has
136 essential for riboswitch function, revealing the importance of metastable states for RNA-based gene r
137  of pathogenic CNVs in this study highlights the importance of microarray analysis in adults with une
138                     These results illustrate the importance of microbial dispersal to animal microbio
139 nteractions with endogenous host glycans and the importance of microbial polysaccharides.
140                                              The importance of microwave irradiation in organic synth
141         In addition, our findings underscore the importance of miRNAs in posttranscriptional control
142  antitumor efficacy of sesamol and unveiling the importance of mitochondria in sesamol-induced effect
143 with low levels of mucosal ATP, highlighting the importance of mitochondrial function associated with
144 and during iPSC reprogramming, demonstrating the importance of mitotic bookmarking in pluripotency.
145                             To better assess the importance of mobile technologies in rhinitis contro
146  Oxidant and Aerosol Study (SOAS) emphasizes the importance of modeling the whole system to understan
147 l saltatory migration in vivo and highlights the importance of MT flexibility in N-C coupling and neu
148 pled with recent preclinical studies showing the importance of multiple neuropeptides in reinstatemen
149                First, we theoretically model the importance of multiple scattering effects and comput
150                      These studies highlight the importance of multiscale imaging of HIV-1-infected t
151                  ScWES provides evidence for the importance of mutations in certain pathways that wou
152                       This work demonstrates the importance of MXene electrode architecture on the el
153                                        Given the importance of N recycling, an important but underest
154 omplex III, and by piericidin, demonstrating the importance of NADH-related ubiquinone reduction for
155                      Our findings underscore the importance of national surveillance and understandin
156                                              The importance of natural gene expression variation for
157                       Our findings highlight the importance of neighborhood disadvantage in influenci
158 ctive vision-to-memory mapping, highlighting the importance of neural oscillations for the interactio
159 es inflammatory ILC2 responses, highlighting the importance of neuro-immune crosstalk in allergic inf
160                                     Although the importance of neuronal progenitors in vascular devel
161 models reproduce these results and highlight the importance of neurons coding feature values for para
162                                      Despite the importance of neurovascular disease and subsequent i
163                          Methods for ranking the importance of nodes in a network have a rich history
164 in the higher energy analogues, underscoring the importance of noncovalent interactions in enantio- a
165 ith the hydrophilic ones, which demonstrates the importance of nonpolar driving forces on the structu
166               Our studies further illustrate the importance of normal membrane trafficking in the phy
167        Taken together, our results highlight the importance of not only CFTR but also BK channel func
168        Collectively, these studies highlight the importance of nucleobase desolvation as a key physic
169 ate size on this observation, which revealed the importance of oligonucleotide distribution in this o
170                                        Given the importance of orchestrating cell migration, it is vi
171                The study findings underscore the importance of organizational safety practices and cu
172 xidative function of p66Shc, and demonstrate the importance of p66Shc lysine acetylation in vascular
173 egnancy with ID in offspring and investigate the importance of parental mental illness for such an as
174 ed network-based cellular signatures.Despite the importance of pharmacological and functional genomic
175                     Studies have established the importance of physical activity and fitness, yet lim
176                             We also document the importance of PKR, TRIF, and TBK1 in cytokine secret
177            Our previous studies demonstrated the importance of PLCgamma2 in osteoclast (OC) different
178 rsus homeostatic regeneration, and highlight the importance of postmitotic cell growth in gut epithel
179 entify key players in liver regeneration and the importance of posttranslational regulation of growth
180 omatic and psychiatric diseases, emphasizing the importance of precise neuronal control of effector p
181                           These data suggest the importance of preventing severe forms of DR to mitig
182  of molecular disorder, this work emphasizes the importance of prioritizing structural compatibility
183  effect in the aversive procedure, revealing the importance of procedural differences to the demonstr
184                     These findings highlight the importance of prompt diagnosis, care engagement, and
185 ducation of hunters and the public regarding the importance of proper preparation of wild game prior
186        In addition, our study casts doubt on the importance of protein quantity of PINK1 in the recru
187 pe in Ksp-cre;Pth1r(fl/fl) mice, emphasizing the importance of PTH in inhibiting Cldn14.
188        Taken together, our results highlight the importance of RALY as an indirect regulator of trans
189                    These results demonstrate the importance of reactivation of AR-regulated lipid bio
190                                 We emphasise the importance of recognising its diagnostic criteria an
191                  Our data not only highlight the importance of regulating the epigenetic landscape du
192 ng [4] and brain disorders [5], highlighting the importance of resting-state measurements for underst
193                         Our study emphasizes the importance of rethinking the impacts of coastal deve
194                      Our findings underscore the importance of retroviral structural proteins for int
195 tion of TIA1 mutations in ALS/FTD reinforces the importance of RNA metabolism and SG dynamics in ALS/
196                      These results highlight the importance of seagrass ecosystems to the health of h
197                              This highlights the importance of selecting from both chemo- and biocata
198                                        Given the importance of selective information processing in ne
199                   Thus, our study highlights the importance of SENP8 in maintaining proper neddylatio
200                      These results highlight the importance of sequence context for alt-EJ repair and
201 on channels in platelets is unclear, despite the importance of shear stress in platelet function and
202 creasing temperature for all densities, with the importance of short-range impurity scattering result
203 odel highly predictive of relapse highlights the importance of social-emotional functions in cocaine
204            The current study aims to explore the importance of SOCS-3 and SOCS-4 in regulating cellul
205                      These results highlight the importance of soil- and leaf-P in defining the photo
206     Comparison to previous studies indicates the importance of some key model aspects including clima
207 as in artificial manufactures, combined with the importance of some species as model experimental sys
208                    These findings underscore the importance of specific combinations of transcription
209 t new loci associated with COPD, demonstrate the importance of specific loci associated with lung fun
210 he spouse alters this association highlights the importance of spouse characteristics for the behavio
211                    Our analysis reveals that the importance of spreaders is fixed by the subcritical
212                                        Given the importance of STEM careers as drivers of modern econ
213  mood disorders; however, only recently have the importance of sterile inflammatory processes in this
214 hat persisted for up to 10 days, after which the importance of stochastic processes increased.
215 asonality of seafloor POC fluxes, as well as the importance of studying a broader range of seafloor e
216 gene regulation and expression, highlighting the importance of studying ASE at the gene isoform level
217                    These results demonstrate the importance of studying protein-protein complex forma
218                       These data demonstrate the importance of subcutaneous tissue on microneedle per
219 n these uterine leiomyoma subtypes emphasize the importance of subtypes and genotypes in designing no
220                                 Yet, despite the importance of such experiments for translational med
221              Recent studies have highlighted the importance of such metabolic regulation in the endot
222                     These findings highlight the importance of surface soil biodiversity for soil fer
223 n a diet-induced obese dog model, suggesting the importance of systemic inhibition of DGAT1 for body
224                                     However, the importance of TGF-beta-Smad2/3 signaling in fibrobla
225 e diterpenoid salvinorin A have demonstrated the importance of the acetoxy functionality on the A-rin
226                 Emerging evidence highlights the importance of the actin cytoskeleton in modulating i
227 cted rate enhancements, our study highlights the importance of the atomistic and chemical nature of t
228                               We demonstrate the importance of the barley reference sequence for bree
229                                              The importance of the C-N bond has stimulated the develo
230                    These results demonstrate the importance of the CeA in regulating responses to rew
231  containing site-directed mutations revealed the importance of the conserved DDE motif and a W residu
232  pincer-type mer-C,N,S ligation, emphasizing the importance of the fac-C,N,S-iron(II) motif in promot
233                                 We highlight the importance of the flow asymmetry by showing that man
234                                 To elucidate the importance of the GPB and GPC receptors relative to
235            Not only do our results highlight the importance of the gut microbiome in honeybee health,
236     This review provides a broad overview of the importance of the host microbiome and accumulating k
237 ordered as L35<F68<L64<F127<P123, indicating the importance of the hydrophobic environment for the co
238                        Our results highlight the importance of the kinin-kallikrein system in the reg
239                        Our results emphasize the importance of the ocean for ice sheet stability unde
240                     Their findings highlight the importance of the oral cavity as a potential reservo
241                    These results demonstrate the importance of the p38-MNK-eukaryotic translation ini
242                      Furthermore, we analyze the importance of the pair-relationships extracted by PS
243 e under threat of extinction, thus revealing the importance of the preservation of the natural Sardin
244 n, requiring the panel to evaluate and weigh the importance of the problem, the confidence in the evi
245                     These findings highlight the importance of the protein environment for re-adjusti
246                             In order to test the importance of the raft environment on prion propagat
247        Overall, the discussed data highlight the importance of the research direction defined as "Iol
248                    These results demonstrate the importance of the Rev-erbbeta HRM in regulating inte
249                    These results demonstrate the importance of the spectrin cytoskeleton both at the
250                         This study addresses the importance of the structural changes in P10 during i
251  unanswered question was remaining regarding the importance of the structural dimensionality.
252 acts on housing stability and STIs highlight the importance of the supportive housing program for you
253 t for regulated release of Dpp, highlighting the importance of the temporal pattern of Dpp presentati
254                 Despite broad recognition of the importance of the third dimension5,6, current lithog
255 allow water volcanic pCO2 gradient to assess the importance of the timing and duration of high pCO2 e
256 e interaction with the HEXIM protein confirm the importance of the triple interactions at the signatu
257                                 Highlighting the importance of the variables in encapsulated products
258 itive to vertical pitch, which could reflect the importance of the vertical (gravity) axis as a refer
259                           The results showed the importance of the volatile compounds produced from a
260 iates from this universal curve, pointing to the importance of thermal activation of carriers out of
261                                     However, the importance of these alpha-chains in disease pathogen
262                                     Although the importance of these cells is clearly recognized, the
263  sensitivity for fibril formation supporting the importance of these charged side chains in fibril fo
264                                   We explore the importance of these demographic and genetic properti
265                                              The importance of these diseases as well as the prolifer
266                     To more fully understand the importance of these findings for conservation and ma
267                                              The importance of these findings translated to the natur
268    ChIP-seq and genetic analyses demonstrate the importance of these interactions for recruitment of
269                                              The importance of these materials and their ubiquity hav
270                                      Despite the importance of these two well characterized neuron ty
271                                      Despite the importance of this fine regulatory system, the molec
272 rmation of the ternary complex, highlighting the importance of this interface for direct regulation o
273 of saccade-related accumulation, emphasizing the importance of this parameter in biologically plausib
274 tard7 promotes uptake of PC by mitochondria, the importance of this pathway for mitochondrial and cel
275  methylation in normal human development and the importance of this process in human developmental di
276 cetylated at lysine 14 (H3K14Ac), validating the importance of this specific acetylation mark for PBR
277 ain positive feedback, perhaps indicative of the importance of this state for species survival.SIGNIF
278 e is mostly driven by a single strategy, but the importance of this strategy on long term dynamics is
279                                      Despite the importance of this structure, it is unknown which fa
280 lue and antioxidant activity which signifies the importance of this vegetable for the Mediterranean d
281 traditional approach to diagnosis emphasises the importance of thorough clinical and laboratory evalu
282                                              The importance of thymic epithelial cells (TECs) is evid
283         The findings of this study highlight the importance of thyroid hormones during pregnancy for
284 so affected neuronal migration, highlighting the importance of tightly regulated CAMK2 auto-phosphory
285 cell behaviour is widely recognized, whereas the importance of tissue material properties, in particu
286                            Staff highlighted the importance of training, but staff training appeared
287                More generally, it highlights the importance of transient dynamics, and the relevance
288                                              The importance of understanding patient preferences for
289                       Our results underscore the importance of understanding the interplay among disp
290 ical significance of these motors emphasizes the importance of understanding the molecular basis of t
291                               We demonstrate the importance of undervaccinated subpopulations, using
292  for querying pathogen behavior in vivo, and the importance of validating in vitro studies of antibio
293                 Our data further demonstrate the importance of Vascular Endothelial Growth Factor (VE
294                                      Despite the importance of vasodilation in cardiovascular homeost
295                                              The importance of VEGF produced by ALL cells in mediatin
296 lizations and vocal morphology, highlighting the importance of vocal physiology in understanding the
297                                              The importance of VPDant suggests that atmospheric droug
298                                              The importance of water availability in driving context
299                     These results illustrate the importance of wheat fructan and sucrose content and
300  normal differentiation phenotype indicating the importance of Wnt signalling in regulating this proc

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