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1 10(-8)), as well as a new independent SNP at the known 2q13 locus (rs9308731, BCL2L11, P=1.00 x 10(-1
3 een the two datasets, with 24.7% or 42.5% of the known 49.0 kbp of LGT sequence predicted correctly,
4 All observed density can be attributed to the known 80 subunits of the individual complexes, inclu
5 ntiOxCINs, these molecules take advantage of the known ability of the triphenylphosphonium cation to
8 e in the intramolecular rotation, increasing the known activation energy to rotation from 8.5 to 10.6
10 The high frequency of this procedure and the known adverse effects of repetitive pain in neonates
11 up into the skin and contributes to many of the known adverse side effects of ATRA treatment, includ
12 widespread zoonotic transmission and adds to the known aetiologies of infectious diseases for this re
14 ng two weakly mutagenic aromatic amines, and the known alkaloid comutagen norharman along with two re
17 ociated with major TAL effectors that target the known alternative S genes OsSWEET14 and OsSWEET13.
18 review, we provide an up to date overview of the known AMPylating enzymes, the regulation of these en
19 e produced several simple models inspired by the known anatomical structures and neuronal responses w
22 various algorithms and to benchmark against the known ancestral genotypes and ancestral phenotypes.
25 s review focuses on our current knowledge of the known and potential interaction of the microbiome in
27 conformation is a novel mechanism to explain the known anti-inflammatory effects of this compound, in
28 D4.2 lacks epitopes associated with half of the known antigenic sites, which significantly impacts o
29 gainst P. falciparum parasites comparable to the known antimalarials, chloroquine and mefloquine.
32 ly, this peptide motif is sequestered within the known ASF1-H3-H4 interface, raising the question of
33 sease has been relatively neglected, despite the known association between severe tricuspid regurgita
34 Our work is the first to demonstrate that the known association between WT1 expression in breast c
36 he associations with EA are far smaller than the known associations with the biologically proximal en
42 ndings from during the past decade expand on the known benefits of breastfeeding for women and childr
43 throughput screening hit anthranilic acid 4, the known benzofuran analogue 5, and the benzothiadiazin
49 The reaction of (C5Me5)3Th, 3, with H2 forms the known (C5Me5)3ThH as the sole thorium-containing pro
52 response enhancement effect did not require the known catalytic activity of CheR, but did involve a
58 accomplished computationally in reference to the known "closed" apo-PBP2a X-ray crystal structure sta
59 inding to CPSF6, is largely independent from the known cofactors for nuclear entry, and alters integr
60 ulin interacted with the peptides containing the known collagen cross-linking sites and the MMP-1 cle
62 hich Ub adopts a dynamic equilibrium between the known, common Ub conformation and a distinct, second
63 of the BCR signaling network, which captured the known complex cross-talk between the NFkappaB, ERK,
64 %), successfully identifying the majority of the known components of the canonical glycoprotein ERAD
66 that the phenylalanine clamp (varphi-clamp), the known conductance bottleneck in the PA translocase,
67 Its absolute configuration was assigned by the known configurations of the starting compounds and b
70 study provides new mechanistic insight into the known contribution of myeloid cells to muscular dyst
77 fungus, Phomopsis sp. (CMB-M0042F), yielded the known cytochalasins J (1) and H (2), together with f
79 ll review the historical data for D4, review the known D4 ligands, and then highlight new data suppor
80 receptor blockade, a finding consistent with the known dependence of this response on the innate cyto
81 ite predictions in ccmB transcripts based on the known determinants of nucleotide base recognition by
82 terial and archaeal DGR lineages that expand the known DGR range by 120% and reveal a history of hori
84 the other sibling pair, targeted testing of the known disease gene for Roifman syndrome (RNU4ATAC) p
94 demonstrate that our methodology can detect the known effects of drug-induced neuronal inactivity an
96 eveal binding sites that are consistent with the known effects of these molecules on beta2m amyloid f
98 fore suggest that a mechanism in addition to the known electron carrier function of ubiquinone is req
102 ent inhibitor of NMDAR-induced currents than the known endogenous neurosteroid, pregnanolone sulfate
103 of a constitutively active Mek1 (Mek1(DD)), the known ERK activator, restores the tectal stem zone a
106 vesicle priming process that they control to the known etiological mechanisms of psychiatric and neur
107 tsuokella multacida (PhyAmm) in complex with the known eukaryotic second messengers Ins(1,3,4,5)P4 an
108 termitophile so far discovered, pushing back the known evolutionary history of termitophily by approx
110 e provides a personal recollection (with all the known faults of self-reporting and retrospective mem
111 species due to multiple protomers, including the known fluoroquinolone protomers and the new finding
118 f cellular protein levels, which goes beyond the known functions of PRMT5 as a transcription and spli
120 reover, these data also significantly expand the known functions of smORF-encoded microproteins.
121 addition to confirming oncogenic activity of the known fusion oncogenes engineered by our constructio
126 nown Usher genes or in extra-exonic parts of the known genes - to date a largely unexplored possibili
129 There remains a large discrepancy between the known genetic contributions to cancer and that which
131 orrelations represent enzymatic reactions in the known glycosylation pathway, and then predict new bi
134 patients will be highly variable because of the known heterogeneities in signaling pathways among th
135 jor crossover pathways in plants and some of the known homeostatic mechanisms that act during meiotic
136 entify additional residues in the network of the known hotspot residues of different anti-Ebola antib
146 ified 87 cancers in different quadrants than the known index cancer, constituting the basis of this r
147 R imaging-detected multicentric cancers than the known index lesion, and 18 of 73 (25%) (95% CI: 15,
148 eutic and imaging protein conjugates despite the known instability of the resulting products that und
152 in cerebellum appears to be consistent with the known involvement of this brain region in auditory f
153 be related to their known precursors and to the known kinetic isotope effects of enzymes involved in
155 has been modeled using DFT calculations from the known LGO precursors levoglucosan and 1,4:3,6-dianhy
157 de were found in diverse proteins, including the known ligand high-molecular-weight kininogen (HK), a
159 openic phenotype of TIEG1 KO mice as well as the known links between TIEG1 expression levels/allelic
162 ain three important elements: in addition to the known (main) binding site, we identified a linker re
163 on coefficients show the maximum value among the known MAX phases, to date and to the author's knowle
164 and although carboxylation of acetyl-CoA is the known mechanism for generating the distinct plastidi
165 aims of this Review Article are to summarize the known mechanisms of protein translational fidelity a
166 describe how this process is consistent with the known mechanisms of TRAP transporters and consider h
167 ialylated cell adhesion molecules, including the known megakaryocytic markers integrinbeta3 and CD44,
172 this enhanced IBC migration effect, and that the known metastatic oncogene, RhoC GTPase, is necessary
173 icular emphasis is placed on improvements to the known methodologies and recent advances in the field
175 hat Cys-119 or Cys-162 of p38alpha, close to the known MKK3 docking domain, were relevant for these r
177 e renders H2S synthesis by CSE responsive to the known modulators of CBS: S-adenosylmethionine, NO, a
178 unprecedented polyphosphanes in addition to the known monoinserted product LGaP4 (1) are observed.
181 way for RER in RNase HII-deficient cells and the known mutagenic profile of DnaE, we propose that mis
187 ation in the Drosophila model, we can expand the known network of genes involved in disease pathogene
188 ological organization would reliably reflect the known neurobiology of individual amygdaloid nuclei,
189 tors (TF) associated with gene signatures of the known neuroendocrine/epithelial (NE) and non-neuroen
193 n (residues 1-4) of NCC differs from that of the known NOP antagonists, as being slightly slipped dee
197 ted PPy-PFOS was adjusted by polarization to the known open-circuit potential of the solid contact in
198 became markedly activated by cyanide (CN) or the known opener P1075 with a current density that was ~
200 isolated from whole blood and cultured with the known OSM inducers GM-CSF and follistatin-like 1, an
204 eroxisome division in a manner that requires the known peroxisome division factor PEROXISOME AND MITO
205 compounds were selected for the HTS based on the known phenothiazine Ndh inhibitors, trifluoperazine
206 nt a novel rodent model to reproduce much of the known phenotype of CTEPH, including the pivotal path
209 pylori lacks a gene encoding a homologue of the known pimeloyl-ACP methyl ester cleavage enzymes sug
210 ts of volatile compounds, including CO2, and the known plant growth-promoting volatile 2,3-butanediol
212 ved for MT-2 cells and provide evidence that the known poor infectivity of HTLV-1 particles may corre
213 fects on telomere length could contribute to the known poor performance of later-ovulated family memb
217 endent, G-protein conformational change from the known prefusion conformation to an extended, monomer
220 e known anatomy of layer 4 demonstrates that the known proportion and connectivity of inhibitory neur
222 s due to pregnancy are sufficient to explain the known protective effect of full-term pregnancy in ea
223 l innate immune signaling, which complements the known PRRSV-mediated immune-evasion mechanisms.
226 ght into C-C-hydrolyzing enzymes and expands the known range of reactions catalyzed by the amidohydro
227 S1 mutations are functionally different from the known recessive Wolfram syndrome-causing mutations,
228 ion in Welwitschia mirabilis to test whether the known regulatory links between LEAFY and its MADS-bo
229 in layer 4 than in subplate, consistent with the known relay of thalamic information to layer 4 by su
234 ction by MOV10 was unique and independent of the known retinoic acid-inducible gene I/mitochondrial a
235 hreat of hypoxia in the tropics, even though the known risk factors, including eutrophication and ele
236 have an evidence-based discussion regarding the known risk of cutaneous surgical procedures in the s
237 al lesions detected in peripheral fields and the known risks associated with H/Ma and peripheral lesi
238 countries, medical interventions to address the known risks associated with pregnancy and birth have
239 rthermore, OGA is physically associated with the known RNA polymerase II (pol II) pausing/elongation
240 hydroxyapatite (HA) crystals in vitro and on the known role mineralization inhibitors, like PPi, play
244 ffect of PDF on clock gene transcription and the known role of PDF in enhancing PER/TIM stability occ
245 e whether connexin phosphorylation regulates the known role of zonula occludens-1 protein (ZO-1) in g
247 intrinsic antiviral immunity contrasts with the known roles of PIAS proteins as suppressors of innat
248 binding interface that has shifted away from the known RV P-genotype binding sites but is conserved a
252 using logistic regression and correcting for the known sampling fractions from stage 1 to stage 2, ov
254 o the control compound prostratin (1), while the known sesterterpenoid alotaketal C (2), isolated fro
255 itu autophosphorylated protein, we expand on the known set of CPK28 autophosphorylation sites, and we
261 within the CPK28 J domain that overlaps with the known site of intramolecular interaction between the
264 olved in this representation overlapped with the known spatial cell types in the circuit, such as pla
265 nalysis were used together to reveal whether the known species of Fargesia represent discontinuous sa
267 nancy is unknown, but hepcidin regulation by the known stimuli (i.e., iron, erythropoietic activity,
268 also led to dephosphorylation at Ser-555 of the known STING regulator, UNC-51-like kinase 1 (ULK1).
275 structural models for a target protein from the known structure of its homologous template proteins
278 hibitors involved in the pathway, along with the known substrate cleavages and peptidase-inhibitor in
279 ly explained by a microscopic model based on the known surface dynamic behavior under vacuum conditio
280 curs via a degenerative pathway unrelated to the known synapse function of these proteins and involvi
281 ted by the ability of LT-scanner to identify the known targets of FDA-approved kinase inhibitors base
282 these photochemical reactions different from the known thermal chemistry of 1, but the reversibility
283 sor surface were investigated, understanding the known TLR-PAMP interactions, through the exploitatio
287 sequence block 3 (CSBIII), just upstream of the known transcription-replication transition point, su
288 these functional data strongly contrast with the known transcriptional regulation of NRT1.1, which is
289 reefs are associated with more than half of the known tropical dead zones worldwide, with >10% of al
290 rmitilis, suggesting for the first time that the known tropism of RNA bacteriophages may include gram
292 BART miRNA cluster 2, new relationships with the known type 1/type 2 strains are demonstrated, and a
294 Recurrent coding mutations were found in the known UM drivers GNAQ, GNA11, BAP1, EIF1AX, and SF3B
295 While emerging studies are greatly expanding the known universe of RNA-binding proteins, methods for
299 f deep evolutionary relationships(3-5) or on the known, well-classified diversity of life with an emp
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