ライフサイエンスコーパス: the last

1 AIW) temperatures and sea-ice cover spanning the last 1.5 million years (Ma) of orbitally-paced gla

2 ctor (sVEGF)-VEGF165, have been developed in the last 10 years to enhance cell survival, they showed

3 During the last 10 years, studies have mechanistically linked o

4 the presented case, we describe that during the last 10 years, we have collected 28 cases of allergy

5 perienced repeated cycles of innovation over the last 100 million years that include gene duplication

6 marine and terrestrial areas protected over the last 100 years have been colonized by any of the inv

7 rategies for endophthalmitis management over the last 100 years.

8 inter-annual timescale, we showed that over the last 110 years, volcanic eruptions have influenced A

9 e boroughs, had at least 1 sexual partner in the last 12 months, stated willingness to take an STI te

10 d having routine surveillance mammography in the last 12 months.

11 95 schemes, 8 figures and 528 references for the last 12 years and includes the description of the hy

12 ext manuscripts and abstracts published over the last 12 years, from 2005 to March 2011 were reviewed

13 anic synthesis, covering the literature from the last 12 years.

14 ina to reconstruct the EASM variability over the last 145 years.

15 We observed that the last 18 residues of the C terminus ("tail" region) o

16 e of H15 viruses are warranted.IMPORTANCE In the last 2 decades, an apparent increase has been report

17 Over the last 2 decades, it has become apparent that AMPK reg

18 Over the last 2 decades, research has unequivocally shown tha

19 imaging of neuroendocrine tumors (NETs) for the last 2 decades.

20 onstrate a genetic continuity in Europe over the last 20 millennia.

21 Over the last 20 years a number of long-lived mouse mutants h

22 sults from preclinical rodent studies during the last 20 years implicated glutamate neurotransmission

23 a for CAA, in use in one form or another for the last 20 years, are now being reviewed to reflect the

24 of Andean orchid lineages only originated in the last 20-15 million yr.

25 first records worldwide has increased during the last 200 years, with 37% of all first records report

26 tes that the three burial events occurred in the last 2000 calendar years.

27 and migrants that arrived in the region over the last 2000 years.

28 The US swine industry has been impaired over the last 25 years by the far-reaching financial losses c

29 that herbicide use intensity increased over the last 25 years in maize, cotton, rice and wheat.

30 roM throughout the winter mixed layer during the last 25 years.

31 omparison of the 28-day baseline period with the last 28 days of a 24-week trial.

32 However, over the last 3 decades, improvements in intrauterine interve

33 24-38) and had a median of 2 sex partners in the last 3 months (IQR = 1-3).

34 who reported at least 1 complication during the last 3 months of pregnancy, maternal conditions incl

35 During the last 3 weeks, a subset of rats received intravenous

36 nsive overview of the recent progress within the last 3 years.

37 f patients received antineoplastic agents in the last 30 days of life throughout the study period.

38 benzodiazepines (52.1% versus 26.6%) during the last 30 days of life, while diagnoses of opioid use

39 I estimate that warming over the last 30 y is responsible for 59,300 suicides in Indi

40 In the last 30 years, there have been many advances in the

41 complementary to themselves have appeared in the last 30 years.

42 ield of research that has evolved rapidly in the last 30 years.

43 ed the greatest temperature increases during the last 30 years.

44 e cryosphere, geosphere, and atmosphere over the last 30,000 y that led to extensive changes in subse

45 observed increase of AMPP-T and AMPT-P over the last 33 years is explained by eCO2 (39% and 42%) alm

46 ed the full rosters of invited speakers over the last 35 years for four prominent international virol

47 from 1910 to present levels-unprecedented in the last 363 years.

48 poradic outbreaks of Ebola virus (EBOV) over the last 4 decades and the recent public health emergenc

49 ased substantially in the United States over the last 4 decades, driven largely by increases in papil

50 four pandemic GII.4 noroviruses isolated in the last 4 decades.

51 treatment period including at least three of the last 4 weeks.

52 ic variation, and the rate of evolution over the last 40 million years.

53 ives of H. sapiens or evolved gradually over the last 400 thousand years.

54 stimate of global solar wind variations over the last 400 years.

55 as evolved asynchronously three times during the last 5 Myr.

56 gher incidence of positive rim cultures over the last 5 years of the analytic period compared with th

57 ic principles and literature reported during the last 5 years.

58 The massive use of fossil fuels during the last 50 years has generated a large CO2 concentratio

59 C8-C17 CPs, are persistent in sediments over the last 50-80 years, indicating that CPs are persistent

60 At other times during the last 500 million years, particularly during the Cret

61 from the temperate Korean Peninsula (KP) for the last 5500 years in order to compare with Holocene mi

62 Focusing on the literatures from the last 5years, this mini-review summarises the recent

63 se alpha class 2A member 1 gene (MAN2A1) and the last 6 exons in the FER tyrosine kinase gene (FER),

64 ic CDI in hospitals has remained stable over the last 6 years and resulted in fewer complications tha

65 Atlantic Oscillation (NAO), we show that in the last 60 years both high-frequency summer and spring

66 8% started their first hospice enrollment in the last 7 and 3 days of life, respectively.

67 ndom use or the number of sexual partners in the last 7 days, with high levels of consistent condom u

68 lts, with a surveillance period of 2 h after the last administered dose, and a prolonged surveillance

69 ollowing cardiomyocyte loss, which underpins the lasting and severe effects of cardiomyopathy.

70 IgE administration 24 hour and 48 hour after the last AP challenge.

71 s but no further whole-genome duplication in the last approximately 125 million years.

72 6 consecutive months after stabilisation at the last assessed dose.

73 red gravity field differs substantially from the last available estimate and is one order of magnitud

74 m two consecutive alpha-methylation steps on the last beta-keto intermediate to yield an alpha,alpha-

75 and a distinct, second conformation wherein the last beta-strand is retracted to extend the Ser65 lo

76 5 CE) and Holocene fossil specimens spanning the last c.

77 gic extension rates of c. 0.6 mm yr(-1) over the last c. 50 kyr in the eastern Sevier Desert are cons

78 The last calculation assumes EUC dissolved iron concentr

79 ds migrated from Pozzuoli to the location of the last caldera eruption (Mt.

80 MR imaging unit at baseline and 1 week after the last CCl4 treatment.

81 s that has driven neuroscientific enquiry in the last century has been the nature of differences in t

82 feature of anthropogenic climate change over the last century has been the rise in global mean temper

83 Furthermore, data from the last century indicate a rapid increase in primary pr

84 n extensively bred for plumage traits during the last century, but the underlying genes are unknown.

85 During the last century, the pathogenesis of AS has undergone t

86 nomena have been extensively investigated in the last century, the traditional approaches employed in

87 warming of Arctic Ocean bottom water during the last century.

88 nced their breeding phenology by 5-12 d over the last century.

89 ied savanna woody vegetation change spanning the last century.

90 c airways responses were measured 48 h after the last challenge.

91 -5/group) 6 hour, 24 hour, and 48 hour after the last challenge.

92 erns similar to control groups 48 hour after the last challenge.

93 participant was randomized in March 2010 and the last clinic visit occurred in November 2016.

94 e Olfactory Receptor (OR) gene repertoire in the last common ancestor of all bats, as well as that of

95 d C2-specific T44-KIR2DP1(F) encoded on CenB The last common ancestor of humans and chimpanzees had d

96 Over the last decade 65% of our pediatric transplants were SL

97 ral Africa have sustained alarming losses in the last decade [1].

98 truction has witnessed tremendous success in the last decade after the introduction of cadaveric biol

99 vance: Statin use increased substantially in the last decade among US adults, although the uptake was

100 oil price and have considerably increased in the last decade due to the interest to exploit shale gas

101 The last decade established that the dynamic properties

102 The last decade has seen the approval of several new bio

103 It is only in the last decade that sub-cellular resolution of red cell

104 marine viruses has become more apparent over the last decade, a deeper understanding of virus-host dy

105 Within the last decade, a number of studies have documented vis

106 53 53 References 53 In the last decade, analyses of both molecular and morpholo

107 tastatic melanoma has evolved rapidly during the last decade, and patient treatment has become more c

108 For the last decade, chemical control of bacterial virulence

109 Over the last decade, danger-associated molecular pattern mol

110 Over the last decade, extensive genetic and genomic resources

111 Over the last decade, genome-wide association studies (GWAS)

112 During the last decade, high resolution electron microscopy (EM

113 In the last decade, high-content screening based on multiva

114 c criteria and some advances in treatment in the last decade, many areas of mast cell activation synd

115 Over the last decade, numerous investigations have attempted

116 Over the last decade, our appreciation for the contribution o

117 Over the last decade, remarkable progress has been made towar

118 In the last decade, several large-scale transcriptome and i

119 In the last decade, the application of 2-photon intravital

120 During the last decade, the development of improved and novel a

121 Despite significant improvements in the last decade, the treatment of prostate cancer remain

122 molecules has made considerable progress in the last decade, though the disassembly processes remain

123 nomaterials (ENMs) has grown dramatically in the last decade, with increased use in consumer products

124 pancreatitis (HTG-AP) increased rapidly over the last decade.

125 PSMA has become increasingly important over the last decade.

126 tes, ECG standards have evolved quickly over the last decade; pushed by a growing body of scientific

127 y procedures for acute stress induction over the last decades has greatly advanced our understanding

128 During the last decades major advances in understanding the ads

129 Over the last decades, it has been established that chronic a

130 s and asthma has dramatically increased over the last decades, resulting in a high burden for patient

131 liver cancer (PLC) has slowly declined over the last decades.

132 unctivitis has increased dramatically within the last decades.

133 lity has declined in sub-Saharan Africa over the last decades.

134 of the Fennoscandian Ice Sheet at the end of the last deglaciation ( approximately 13,200-12,000 year

135 ter and thermocline radiocarbon content over the last deglaciation in the eastern equatorial Pacific

136 ere and hydroclimate changes occurred during the last deglaciation, although the interplay between th

137 oximately 1.4 m sea-level equivalent) during the last deglaciation, both of which have implications f

138 er timescales of decades to centuries during the last deglaciation, previously recognized only during

139 pics was affected by external forcing during the last deglaciation, remains poorly understood.

140 lating hemispheric and global climate during the last deglaciation.

141 nd deep waters occurred synchronously during the last deglaciation.

142 In these three patients, the last documented visual acuity on the Snellen eye cha

143 ly reported the noninferiority 1 month after the last dose of 2-dose human papillomavirus 16/18 AS04-

144 ng the Dean scale was assessed 4 weeks after the last dose of chemotherapy by unblinded patient revie

145 ociated with less hair loss at 4 weeks after the last dose of chemotherapy.

146 Patients were followed for 16 weeks after the last dose.

147 UPF1 and SMG1, SMG8 and SMG9 also existed in the last eukaryotic common ancestor, 1.8 billion years a

148 At the last evaluation (median 50.0 months [IQR 27.0-78.4])

149 The last event increases chloride efflux, leading to com

150 nonsense mutation c.796C>T (p.Arg266Ter) in the last exon of SERPINB7.

151 The last favours homochiral skyrmions, whose motion is d

152 The last few decades have seen substantial growth in the

153 During the last few decades, the global incidence of dengue vir

154 made in the fabrication of ASC devices over the last few decades.

155 has been increasing at an alarming rate over the last few decades.

156 Research in the last few years has revealed a sophisticated interact

157 Despite slow progress in the field, the last few years have seen an explosion in our knowled

158 Over the last few years, several groups have evaluated the po

159 se in the treatment of malignant melanoma in the last few years, with these drugs now commonly used i

160 ical origin of tannins have been proposed in the last fifteen years, but are generally time consuming

161 chemistry has experienced rapid growth over the last five decades, fueled by elegant work showcasing

162 Over the last five decades, new and unexpected RNA-related ph

163 wn as potential thermoelectric materials for the last five decades, which offer paramount technologic

164 posited over the past 500,000 y and spanning the last five glacial-interglacial periods.

165 The last five introductions into Africa, all from Asia,

166 ondent reported visiting an HCP about CeD in the last five years and the scores for all three validat

167 host disease (cGVHD) has come to fruition in the last five years, generating a clear understanding of

168 the unit observing an increasing workload in the last five years, with meticulous workforce planning,

169 The last follow-up visit was Jan 31, 2017.

170 o different time points during the first and the last follow-up visits.

171 een November 1, 2012, and December 23, 2015; the last follow-up was performed on October 23, 2015.

172 At the date of the last follow-up, the differences in visual outcomes b

173 At the date of the last follow-up, the mean BCVA was 0.15+/-0.24 (20/30

174 e occurred in heteroporphyrin chemistry over the last four decades.

175 o cause earlier snow melt but may not change the last frost-free day of the year, plants that bud ear

176 The output of the second gate entered into the last gate and triggered an exponential hairpin assem

177 a unique set of climate model simulations of the last glacial cycle (120 kyr), that compares well aga

178 After the last glacial cycle, temperate European trees migrate

179 hese species probably colonized Abaco during the last glacial interval but were eliminated when the i

180 e covered by the Laurentide ice sheet during the Last Glacial Maximum (18,000 years before present [Y

181 ed to the eastern Ross Sea shelf edge during the Last Glacial Maximum (LGM) and eventually retreated

182 America for this time period, spanning from the Last Glacial Maximum (LGM) to the mid-Holocene.

183 (15)N/(14)N across the Southern Ocean during the Last Glacial Maximum (LGM), 18-25 thousand years ago

184 ly-induced drainage of Fe-rich waters during the Last Glacial Maximum could have reached the Southern

185 of South Georgia through the transition from the Last Glacial Maximum to Holocene.

186 nt with high abyssal salinities inferred for the last glacial maximum.

187 Greenland and Antarctic temperatures during the last glacial period (115,000 to 11,650 years ago) ar

188 Both tephra were erupted during the last glacial period and a widespread increase in sub

189 of atmospheric CO2 (Ca ) experienced during the last glacial period is hypothesized to have been an

190 des of major atmospheric CO2 drawdown during the last glacial period were linked to iron (Fe) fertili

191 lowlands, the Amazon was widely drier during the last glacial period, with much less recycling of wat

192 er, warmer, wetter, and more isolated during the last glacial-interglacial transition from approximat

193 on, again consistent with proxy evidence for the last glacial.

194 We conclude that the last glaciation of South Georgia was extensive, and

195 The last haemoglobin measurement was also negatively ass

196 e of 78 forest-understory plant species over the last half-century and compare these shifts to change

197 th the frequency of interictal spikes during the last hour of wakefulness preceding sleep.

198 The transition from the last ice age to the present-day interglacial was int

199 modulated the climate system's descent into the last ice age.

200 The lasting imprint of phylogenetic history on current d

201 ment from enrolment through week 41 (time of the last injection).

202 d to pretreatment levels within 9 days after the last injection.

203 In particular the terrace that formed during the last interglacial ( 125 ka) is found discontinuously

204 Recent studies argue that during the Last Interglacial (MIS 5e, approximately 128-116 ka)

205 tified species of Homo at the CM site during the last interglacial period (MIS 5e; early late Pleisto

206 The last interglaciation (LIG, 129 to 116 thousand years

207 tios (SIRs) for cancer were calculated after the last medical contact for urinary tract stones.

208 the terrestrial C budget of the Holocene and the last millennium and constrain LUC emissions.

209 ting a rapid settlement of Madagascar during the last millennium.

210 ombined estradiol/progesterone compared with the last month of leuprolide alone, the placebo month, a

211 chemosis with extended recovery periods over the last months.

212 acuity score at postoperative month 1 and at the last noted clinic appointment.

213 has been 20 years since the cloning of ATR, the last of the three to be identified.

214 idation Event 2.4 billion years ago (Ga) and the last Palaeoproterozoic iron formations, deposited 50

215 The last part is dedicated to understanding and analyses

216 Enrollment started May 24, 2010, and the last patient study visit was November 23, 2015.

217 The last phase coincided with rapid warming since 1985,

218 r not by RT at 40 Gy delivered 4 weeks after the last R-CHOP cycle.

219 nd spectroscopic studies, we have identified the last redox event as being the turnover-limiting step

220 Since the last report published in the 2014 NAR Database Issue

221 h the Cys loop, through interactions between the last residue of post-M4 and Phe(170) of the conserve

222 beta-lactam antibiotics and more importantly the last resort carbapenems, represent a major mechanism

223 Length of time since the last round of MDA and the prevalence of TF among chi

224 ncreased 14-fold compared with 2 weeks after the last RV144 vaccination (14069 vs 999; P < .001).

225 all significantly higher than 2 weeks after the last RV144 vaccination.

226 The last semi-quantitative food frequency questionnaire

227 In the last several decades, efforts on understanding and c

228 ng to a concentration of these components in the last stage of processing (vacuum concentration).

229 el coefficients of independent predictors at the last step after checking for collinearity, likelihoo

230 Fecal excretion of cholesterol is the last step in the atheroprotective reverse cholestero

231 Lipoyl synthase (LipA) catalyzes the last step in the biosynthesis of the lipoyl cofactor

232 Lysosomal membrane fusion mediates the last step of the autophagy and endocytosis pathways

233 nd is released in a shoehorn-like fashion in the last step of the chaperone-mediated proteasome assem

234 The last step of the sequence was modeled by DFT giving

235 adiofluorination, introducing fluorine-18 in the last step of the synthesis, or by a building block a

236 y, a Krische allylation reaction established the last stereocenter, and the lactone moiety was formed

237 Twenty-four hours following the last stressor, rats were bilaterally infused into th

238 Mean length of follow-up after the last surgery was 48.2 months (range, 4-143 months).

239 forest streams in southeastern Madagascar is the last survivor of a once dominant and widespread Meso

240 Over the last ten years, isogenic tagging (IT) has revolution

241 In the last ten years, there has been a dramatic surge in t

242 f its glaciers to climate variability during the last termination more significant than implied by pr

243 The last three decades have witnessed an explosion of di

244 Over the last three decades, mutations causing these disorder

245 In the last three decades, tremendous efforts have been dev

246 on has been on an extraordinary journey over the last three decades.

247 ng evidence for repeated carbon storage over the last three glacial cycles.

248 s Review focuses on findings reported within the last three years.

249 mples from study participants enrolled after the last training sample was collected (validation data

250 hree sentences were removed from the legend 'The last two calculations are discussed in the "Methods"

251 idwestern US have significantly altered over the last two centuries due to historical land-use and cl

252 Research in this domain has rapidly grown in the last two decades and afforded many examples of bioin

253 the field of flexible electronic devices in the last two decades and will certainly lead to a revolu

254 lity to lung cancer have been published over the last two decades but with few consensuses for the li

255 of the Ru-based compounds investigated over the last two decades express their cytotoxicity with a m

256 netic resonance imaging (fMRI) techniques in the last two decades have provided a tool to better unde

257 vances in translational neuroimmunology over the last two decades have revolutionized the treatment o

258 long been regarded as "undruggable" targets, the last two decades have seen an increasing number of s

259 The last two decades of network science have discovered

260 In the last two decades, a large body of evidence has repor

261 Over the last two decades, geogenic arsenic has emerged as a

262 scular events did not markedly decrease over the last two decades.

263 ed in the isolation of over 190 compounds in the last two decades.

264 tion of their emissions at exhaust pipe over the last two decades.

265 in the development of genomic resources over the last two decades.

266 into a major area of chemical research over the last two decades.

267 The mutation removes the last two exons and part of the 3' UTR of DSTYK.

268 y (GWAS) of responses to the question, 'Over the last two weeks, how often have you felt tired or had

269 mprovements and new developments made during the last two years.

270 updates and additional features added during the last two years.

271 atalysed many different reactions already in the last universal common ancestor.

272 are rapidly evolving, there is confidence in the lasting value of meetings for medical professionals.

273 of clusters (roughly a 4-fold increase since the last version of the ATGC database), it is now built

274 e eyes remained unchanged when compared with the last visit before rejection (BSCVA, 0.15+/-0.11 logM

275 occurrence to cataract surgery, the time to the last visit of the follow-up, date of death, or the e

276 At the last visit, the mean intraocular pressure for the te

277 ubbles within perforation plates, which hold the last volumes of air which eventually dissolve.

278 dure on an average complexity patient during the last week of residency training is 90.5% (95% CI: 85

279 Informed consent was provided according to the last will of the donors.

280 ology has experienced dramatic changes since the last workforce study in hepatology over 15 years ago

281 These changes that have occurred since the last workforce study in the prevalence and therapy o

282 ear of life), number of hospital episodes in the last year of life (not involving large-volume parace

283 For all patients, mean cost of the last year of life was pound21 113 (SD 16 881), 17 88

284 portion of the total number of procedures in the last year of life), number of hospital episodes in t

285 15 patients, in the last year of life, and 4 carers under the care of co

286 o drug use disorders and mental disorders in the last year of life, though opioid use disorder diagno

287 oses of chronic noncancer pain conditions in the last year of life.

288 r of large-volume paracentesis procedures in the last year of life.

289 anxiety (25.8% versus 8.4%) disorders during the last year of life.

290 sence of chronic noncancer pain diagnoses in the last year of life.

291 Performance: from the first to the last year of training, the proportion of Performance

292 h "active asthma" (symptoms or medication in the last year, n = 744) were analyzed in this study to d

293 oducts or impurities has gained attention in the last years and is relevant to assess the safety of o

294 The last years have also seen exciting advances in the c

295 h considerable progress has been made during the last years in understanding the SnRK1 signaling path

296 The clustering of illnesses in the last years of life is particularly pronounced in pat

297 One of the challenges of the last years was to explore new materials and arrangem

298 foodstuffs as cereals has been reported over the last years, but few studies are available concerning

299 Over the last years, hypothalamic inflammation has been linke

300 nd treatment intensity has been reduced over the last years.