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1 e on the origin of mirror neurons, stressing the necessity to abandon the dichotomy between genetic a
2 ypothesis is without foundation, underlining the necessity to accept only similarity of sequence and/
4 s of nanomagnetic logic have been limited by the necessity to apply a magnetic field for clocking.
6 ked key benefits at small scales, indicating the necessity to apply models that include finer-grained
7 ristic of all positive-strand RNA viruses is the necessity to assemble viral RNA replication complexe
9 us, while their coactivation may result from the necessity to bind promoters as heterodimers, it may
10 lty of similar discriminations may relate to the necessity to both strengthen rewarded representation
12 ducing IFN-beta pathways, but also highlight the necessity to check autophagy status upon taking 3-MA
15 e at advanced stages of the disease suggests the necessity to consider modulation of the IL-23/Th17 p
16 a G-quadruplex folding funnel and highlight the necessity to consider solvent viscosity in studies o
17 asevarion switching in NTHI pathogenesis and the necessity to considered phasevarion regulation when
18 racterization of the patients, there is also the necessity to determine the drug-clearance properties
23 emia after cessation of HAART and underscore the necessity to develop therapies directed toward such
24 otential to improve recovery, and underscore the necessity to distinguish the role of tonic and phasi
25 idelity and its control has been hampered by the necessity to employ complex DNA templates requiring
30 thin a multidomain protein, achieved without the necessity to express the individual subunits separat
31 mbled particles with spherical symmetry, and the necessity to fill space at uniform density within th
32 e patients developing tuberculosis emphasize the necessity to find new antitubercular targets and dru
33 ay be related to its unique binding site and the necessity to fit its bulky macrocycle into this clef
34 le steps of viral replication cycle indicate the necessity to further investigate BBI as an alternati
35 These techniques have limitations including the necessity to generate separate calibration curves fo
36 al mandates and authority to set priorities, the necessity to greatly improve the quality of care, an
38 from experience is used actively, relieving the necessity to hard-wire all connections and allowing
40 xity of the PTP-PEST interactome underscores the necessity to identify its interacting partners and p
41 d with standard chemotherapy has highlighted the necessity to identify targeted therapies that can im
42 tions of this exciting technology as well as the necessity to identify the mechanisms underlying any
43 ow over the sensing interface (i.e., without the necessity to implement an additional regeneration st
46 uses, but this effort is often encumbered by the necessity to initially identify compounds of interes
48 p2 domain contains determinants which confer the necessity to interact with cyclophilin A for efficie
49 tumor cell-microenvironment interactions and the necessity to interpret experiments taking the contex
50 ase (RT) appears to have been constrained by the necessity to maintain function within an asymmetric
51 nd is over-expressed constitutively, without the necessity to manipulate factors such as cell growth
52 complex in HCMV vaccine design and emphasize the necessity to monitor the integrity of the pentameric
53 f possible chemical modifications highlights the necessity to obtain structural information about the
54 ctivity to promote H5N1 infection underlines the necessity to optimize management strategies for a pl
56 plication of this modification is limited by the necessity to prepare corresponding acylated tRNA by
60 were only partially congruent, underscoring the necessity to probe HCMV immunomodulation using speci
61 challenge to developing a dengue vaccine is the necessity to produce fairly uniform protective immun
62 with raised expectations of next of kin and the necessity to provide early predictions of long-term
64 COPs during sun drying and storage indicate the necessity to re-evaluate the processing and storage
65 sociation studies are challenging because of the necessity to realistically model the underlying alle
67 equirement for these structures derives from the necessity to regulate the directionality of recombin
68 o avoid these planetary nitrogen burdens and the necessity to remediate this problem, we foresee the
70 NCX3-AC compared with NCX3-B is in line with the necessity to restore Ca(2+) levels in the sarcoplasm
71 ral composition and fatty acids profile) and the necessity to revalorize and protect its traditional
72 ring the post-hospital transfers, indicating the necessity to review the appropriateness of medicatio
73 onsiderable programmatic implications (e.g., the necessity to screen for iron status before intervent
74 termining ovarian cancer risk, and highlight the necessity to screen for missense alterations as well
75 ng biological mechanisms, but also highlight the necessity to seek optimal regimens of continual oxyt
77 Using a nonfluorescent acceptor eliminates the necessity to spectrally isolate the donor fluorescen
78 effect sizes of single genetic variants, and the necessity to statistically correct for testing milli
80 who harbor CD79 mutations also illustrating the necessity to stratify DLBCL patients according to th
82 of even a single large inversion, confirming the necessity to thin SNPs by linkage disequilibrium at
83 sembles, there are downsides, most obviously the necessity to trade-off reversibility against structu
84 d for trained panel in the first lot confirm the necessity to train always before a sensory procedure
85 high cost of colony-stimulating factors and the necessity to treat large numbers of patients who do
86 tual disability disorders, thus highlighting the necessity to understand Las1 regulation and function
87 entering the human body, our data emphasize the necessity to understand the biological role that the
88 nt technologies is steadily growing, driving the necessity to understand the interaction of these new
89 widely used actin-binding domain underlines the necessity to understand their structural interaction
92 s, often containing similar information, and the necessity to use complicated tools to achieve the de
93 trolled RCTs seem to diverge, which stresses the necessity to use placebo in the control arms of thes
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