ライフサイエンスコーパス: the overall

1 The overall 1-, 5-, 10-year patient and graft survival o

2 rs (25th, 75th percentiles, 1.0, 4.3 years), the overall 1-year and 5-year cumulative incidence of mo

3 Finally, the overall 1-year mortality among patients with inciden

4 The overall 3-day, in-ICU, and in-hospital mortality rat

5 The overall 30-day incidence of postdischarge VTE was 0.

6 The overall absolute increase in breast cancers diagnose

7 tiviral defenses by limiting ISG expression, the overall abundance of ISG15 monomer and protein conju

8 significant absolute CVD risk reduction, but the overall ACCORD-BP participant sample was skewed towa

9 The overall accuracy of the Memorial Sloan Kettering Can

10 have been developed and refined to estimate the overall activation energy and its component parts, a

11 The overall activation energy of the process must be lar

12 action mixtures of various agents to enhance the overall activity of a cocktail of multiple enzymes a

13 n act at multiple sites and thus, impinge on the overall activity of a distributed network of neurons

14 e the importance of the brain-liver pathway, the overall activity of liver-related neurons in control

15 Therefore, the overall activity of VGLUT3 is not proportional to th

16 The overall age-standardized prevalence (95% confidence

17 We evaluated the overall and site-specific incidence of cancer in sub

18 This study aimed to assess the overall and thyroid cancer-specific survival in a la

19 t contributions from different mechanisms to the overall anti-silencing function of the CBX3 element.

20 ive contribution of arginine CDR residues to the overall antibody affinity.

21 g, thereby increasing the risk of failure of the overall antibody discovery program.

22 The overall approach of this work provides an effort to

23 tion, or angle, is an important component of the overall architecture and depth of the root system; h

24 However, the overall architecture and functions of CST and RPA ar

25 le EM analysis revealed, for the first time, the overall architecture of the MCM-MeaB complex, which

26 regression modelling was used to investigate the overall associations between five lifestyle factors-

27 Comparison of the overall associations with published results in Weste

28 The overall attempt model revealed adolescent consultati

29 The pooled estimate for the overall attrition prevalence among general surgery r

30 tly increasing the risk of fall and reducing the overall autonomy.

31 The overall average number of injections during this tim

32 uctance; the cross-point potential represent the overall/averaged surface potential difference across

33 omal degradation and, in doing so, determine the overall beta-cell incretin responses.

34 Additionally, the overall binding capacity of 293T/SL-alphaPEG cells f

35 se force vectors were co-ordinated such that the overall body sway response was always aligned with t

36 contributing to a concerted effort to reduce the overall burden of HCV infection.

37 d a decrease in 1-year HF mortality, whereas the overall burden of HF continues to increase.

38 ch was found to contribute differentially to the overall bursting pattern of the promoter during basa

39 and how subpopulations of beta-cells control the overall [Ca(2+)]i response and insulin secretion dyn

40 The overall cancer standardized incidence ratio was 1.5

41 reduction in layer V (CTIP2+) neurons, while the overall cell density of the cortex is unchanged.

42 der illumination, with the aim of increasing the overall cell efficiency.

43 les, called the marginal band, that flattens the overall cell morphology by pushing on the cell corte

44 .g. homeostasis of total metabolite pool) to the overall cellular physiology (e.g. coordination of ca

45 s cereus sphingomyelinase (bSMase) increases the overall ceramide concentration in the plasma membran

46 do and humidity feedbacks also contribute to the overall change in feedback, but are unexplained by s

47 ntal alterations on ecosystem functions, and the overall change in system multifunctionality are scar

48 However, most existing methods only model the overall change of a gene set, yet completely overloo

49 al cuff pressures of 10, 20, 30 and 40 mmHg, the overall changes in arterial volume distensibility re

50 and HeLa cells remained high, which improved the overall characteristics.

51 remains for follow-up measurements to extend the overall chemical coverage.

52 The overall claustrophobic event rate was 9.8% (640 of 6

53 The overall clinical response rate was 52% (9 of 17) (6%

54 bserved to increase the electron affinity of the overall cluster, providing a noncovalent method of t

55 le, and late timing of maximal FEV1 loss, in the overall cohort (n = 18,387).

56 d in-hospital mortality declined slightly in the overall cohort from 9.3% to 8.9% (P<0.001).

57 The overall cohort showed increasing levels of FG and de

58 with that of emerging mechanisms highlights the overall complexity of GBM treatment resistance while

59 While the effect of drought on the overall composition of prokaryotic and eukaryotic co

60 rkflow and the used analysis tools to reduce the overall computational processing time, and concomita

61 The overall conclusion of these results is that Clp1 pla

62 While the overall concordance between the two maps is high, th

63 However, the overall conformation of the dysferlin protein is unc

64 alysis shows that different positions within the overall conserved GAIT element structure contribute

65 al loading and interstitial flow accelerated the overall corrosion rate, leading to loss of mechanica

66 ed the occurrence of POPF without increasing the overall cost of care.

67 The overall cross-sectional progression rate of 0.56 poi

68 as estimated to be approximately one-half of the overall current peak.

69 formation is dramatically suppressed, while the overall current through the cell, correlating with t

70 The overall data indicates extended angular benzannelati

71 The overall decrease in efficiency of extension relative

72 Our study proves that despite the overall decrease in FL concentration, accumulation o

73 The overall detection rate of people unaware of their HI

74 revealed several methodological issues, but the overall direction of biases would reduce the positiv

75 ar stresses, which surprisingly do not match the overall direction of the flow.

76 The overall discrimination potential of strontium isotop

77 ry, such non-Boltzmann effects can influence the overall dissociation rate in the gas.

78 AV pathogenesis and expands our knowledge on the overall diversity of viral glycoprotein-mediated ent

79 We found that the overall drug collection covers a wide CCS range for

80 mbined the data from the 2 groups to examine the overall effect of overfeeding on the DNA methylation

81 The overall effect of PEEP is primarily related to the b

82 l tool, in vivo studies allow observation of the overall effect on a living organism.

83 th and neonatal mortality but did not report the overall effect on perinatal mortality, while the oth

84 Our results show that the overall effectiveness of land consolidation in impro

85 hese adverse outcomes are needed to maximize the overall effectiveness of supplemental feeding progra

86 We tested the overall effects of estrogen receptors on the immune

87 AD51 at DNA double-strand break sites and in the overall efficiency of HR.

88 unbound negative and positive particles with the overall electrical charge being roughly zero.

89 Surface functional groups contribute to the overall electron flux of pyrogenic carbon to a lesse

90 The overall-electronic effect demonstrates an electron-r

91 at specific mutual orientations, thus tuning the overall energetic landscape and ensuring highly effi

92 f the closed-to-open TM domain transition in the overall energetics of receptor activation, we design

93 The overall energy metabolism was found to be strikingly

94 MPES reduces the overall energy requirements thereby greatly expandin

95 Beyond the overall energy-entropy compensation, a similar compe

96 While these analyses clearly demonstrate the overall enrichment of disease risk alleles on gene r

97 e cancellations resulting in small change in the overall enthalpy of the protein, thus making it diff

98 l applications has the potential to decrease the overall environmental impacts associated with extrac

99 We found 1 standard deviation increase in the overall EQI (worse environment) was associated with

100 jugated) version of that beam; another gives the overall equality of the sums of the emissivities and

101 The overall estimate for open repair also was higher in

102 6%] of 54, and 44 [92%] of 48 patients), and the overall estimated probability combining all timepoin

103 rders and enhancing memory, but no review of the overall evidence of C. asiatica and cognitive functi

104 was that an alpha of 2.5% would not minimize the overall expected harm to current and future patients

105 It resulted in a decrease in the overall flux through the shikimate pathway, and a re

106 Although the overall fold and catalytic center are conserved rela

107 This engineered cyclic peptide maintained the overall fold of the naturally occurring cyclic pepti

108 they contributed little to the restraint of the overall fold.

109 es provided the final N-acylguanidines, with the overall formation of one C-C and two C-N bonds, in m

110 nation experienced a significant increase in the overall frequencies of IFNgamma(+), TNFalpha(+), and

111 the most effective treatment in maintaining the overall fruit quality.

112 ntually result in changes in other parts, if the overall function is to be conserved.

113 range of SIRT5 targets have been identified, the overall function of SIRT5 in organismal metabolic ho

114 s related to Okazaki fragment initiation and the overall functioning of DNA replisomes.

115 al Drd2 knockout model studied here revealed the overall fundamental contribution of D2R in motor fun

116 of the ribosomal protein reserve to maximize the overall gain in biomass during the feast.

117 Although the overall genetic diversity between these two cultivat

118 The overall genomic impact of this decline included the

119 The overall goal of this review is to examine current kn

120 t of subjects dropped out, with half (10% of the overall group) due to persistent gastrointestinal sy

121 e unique contributions CHY4 and MMSD make to the overall growth and viability of plants.

122 The overall health care cost could have decreased by $29

123 HER2 testing in breast cancer did not affect the overall HER2-positivity rate or the proportion of pa

124 oscillators and, hence, crucially impacts on the overall hierarchical connectivity patterns of oscill

125 esired disease-causing T cells while keeping the overall host immunity intact.

126 atients with HS (26.2% men and 73.8% women), the overall HS prevalence in the US population sample wa

127 er to N on the nickel surface, beneficial to the overall hydrogen evolution process.

128 finity of the incoming dNTP is controlled by the overall hydrophobicity of the nucleobase.

129 The overall incidence of epilepsy in children aged 28 da

130 In the propensity-matched cohort, the overall incidence of POAF was 53.9%.

131 The overall incidence of suicide attempts during methylp

132 udies in order to pool results and determine the overall incidence rate of gastric cancer for patient

133 The overall incidence rate of PEx was 521.9 per 10000 pe

134 Owing to the overall increase in herbal infusions' consumption, t

135 Research on NBD2 has also been hampered by the overall instability of the domain and the difficulty

136 The overall intent-to-treat minimal residual disease-neg

137 The overall inter-observer agreement in response assessm

138 The overall inter-observer agreement in the CT-based res

139 The overall lack of association between maternal PHIV st

140 We propose that the overall lack of changes in synaptic function and pla

141 This study suggests that the overall landscape of the BNSTALG in the primate and

142 ation), treatment of these compounds reduced the overall level of cellular filamentous (F) actin, slo

143 l participant cooperated previously affected the overall level of cooperation, instead of changing th

144 st likely due to limited seed dispersal, but the overall level of differentiation between subpopulati

145 Torque Teno virus (TTV), which might mirror the overall level of immunosuppression and thus help det

146 latory sites control the kinetic rather than the overall level of PLZF expression.

147 onged arrest caused by nocodazole treatment, the overall levels of the CDC20-MAD2 complex are gradual

148 erturbations, which has a profound effect on the overall lifetime of the complex.

149 This coalescence delayed the overall lipid digestion kinetics.

150 ent lower-level (microscopic) processes from the overall (macroscopic) response remains a crucial cha

151 n the harms of screening but determined that the overall magnitude of the harms of screening and trea

152 , therapies are similar between the two, and the overall management of acute myocardial infarction ca

153 The overall matched odds ratio was 73.1 (95% CI 13.0-inf

154 In the overall MATRIX population, fluoroscopy time and DAP

155 The overall mean prevalences of primary H pylori resista

156 The overall mean rate of VF change for these patients wa

157 Our study reveals conservation of the overall mechanism of ribonucleotide excision repair

158 Herein, we investigate the overall mechanism of this reaction using density fun

159 thought to be activated by upstream kinases, the overall mechanism remains obscure.

160 ited upon its serine phosphorylation by mTOR The overall mechanisms by which TFEB activity in the cel

161 Without additional data processing, the overall median absolute relative difference (median

162 At the hospital level, the overall median risk-standardized rate of CRT-D use w

163 The overall median survival for the cohort in the presen

164 The overall methodology may find uses for the classifica

165 , without and with detergent, respectively), the overall microplastic fiber length profile remained s

166 The overall mortality and CVE rates in the cohort were 0

167 to defining composite measures encompassing the overall multimodal care pathway and capturing succes

168 -eight genes were significantly mutated, and the overall mutational load was associated with APOBEC-s

169 lution mass spectrometry (LC-HRMS) to assess the overall N-oxide formation during the pilot-scale ozo

170 The overall near infra-red (NIR) emission intensity of Y

171 ent models of Goltz syndrome cannot estimate the overall neocollagenesis and marked shift in collagen

172 hesis of insertion, as they presumably limit the overall net pushing force.

173 The overall net reclassification improvement and integra

174 plays a crucial role in properly evaluating the overall network robustness in terms of its future re

175 ted behavioral science compares favorably to the overall NIH grant success rate (approximately 18%),

176 ng advantage of small, periodic decreases in the overall noise structure.

177 BI-RADS category 3 classification; however, the overall number of patients recommended for short-int

178 e annotations provided by InterPro, increase the overall number of residues annotated and allow more

179 The overall odds ratio (OR) for ER visits for GI illness

180 well as lipid oxidation derived odorants to the overall odor of rice proteins.

181 The overall operative complication rate during training

182 ghly, or new degrees of freedom are added to the overall optimization problem.

183 target S. mutans biofilms but do not disturb the overall oral microbiome are available.

184 cia independently contributes to and worsens the overall oxidative burst deficits in CF MDMs compared

185 We found that the overall pace of marsh development was largely unaffe

186 ple neural networks that interact to produce the overall pain experience.

187 In the overall patient population, the most common grade 3

188 Unlike the overall pattern in AML, those patients with CN-AML h

189 confirms the low contribution of WG foods to the overall pattern of foods consumed in the UK.

190 The overall per-vessel diagnostic accuracy of FFR-CT was

191 Four parameters are assessed to understand the overall performance and elucidate the limiting react

192 Simulation studies illustrate the overall performance of our approach.

193 ence over the charging process and therefore the overall performance of the SC system.

194 th HIV infection in the United States during the overall period.

195 or in offices) contributed significantly to the overall personal exposure, which cannot be included

196 e of PGE2 onto its target neurons and not on the overall PGE2 production in the brain.SIGNIFICANCE ST

197 plasticity can be a major factor in shaping the overall phenotypes of genetic neuropsychiatric disor

198 numbers, raising fundamental questions about the overall physiological role of neuroligins.

199 ercutaneous coronary intervention (PCI), but the overall picture remains inconclusive and warrants fu

200 The overall polyphenol bioaccessibility in the stomach w

201 ard ratio [HR], 0.99 [95% CI, 0.94-1.03]) in the overall pooled cohort; with CEE plus MPA, the HR was

202 The overall pooled prevalence of depression in patients

203 ual congeners, were strongly associated with the overall POP load.

204 in apparent proportion to their frequency in the overall population based on independently derived in

205 ts with Caprini scores </=6 comprised 75% of the overall population, and these patients did not have

206 % vs LFT: 29%, P = 0.290), neither regarding the overall population, nor in the colon (FFT: 23% vs LF

207 graine days per month at baseline was 8.3 in the overall population; by months 4 through 6, the numbe

208 er (ket2 = 5.0 M(-1) s(-1)), consistent with the overall postulated mechanism.

209 l halide perovskite solar cell can influence the overall power conversion efficiency.

210 em extracts fluid from these tissues against the overall pressure gradient are unknown.

211 The overall prevalence among HIV-positive women was 1.3%

212 The overall prevalence of any HPV infection was 45.2% (9

213 The overall prevalence of depression in patients with MC

214 Using Sanger sequencing, the overall prevalence of HIVDR mutations was 7.6% (5/66

215 d prevalence estimates from various studies, the overall prevalence was 0.85% (95% CI 0.65-1.04).

216 ome measures, interpretation of results, and the overall process of evaluating candidate medications.

217 event as being the turnover-limiting step of the overall process.

218 The overall projected D/100K will decrease from 2.53 to

219 The overall proportion of beneficiaries that first recei

220 d significant increases were demonstrated in the overall proportion of vertebrate viral sequences fol

221 ation ranged widely across interventions and the overall quality of evidence was very low.

222 The overall quality of the evidence was high.

223 Notably, the overall radiative forcing of open-water fluxes (3.5

224 in reaction rate between the crystal faces, the overall range of rate variability, and the rate comp

225 The overall rate of conversion to open laparotomy was 10

226 The overall rate of primary nonadherence was 31.6% (n =

227 Although the overall rate of screening-detected cancers was simil

228 The overall rate of serious adverse events did not diffe

229 ting, VF progression was noted in 15.8%, and the overall rate of VF loss was -0.12+/-0.51 dB/year.

230 We found that the overall rate-limiting step for aldol cleavage shifte

231 by over an order of magnitude and increases the overall reaction rate.

232 s stable even through late adulthood despite the overall reduction in perceptual competence.

233 tive transient motion analyses revealed that the overall reduction of vesicle mobility, and specifica

234 For the LBC-screened group, the overall referral and detected CIN2+ rates were 27/99

235 the negatively biased electrode, increasing the overall resistance of the thin film.

236 The overall response rate (ORR) was 21% (14/66), and 15%

237 In the efficacy-evaluable population, the overall response rate (ORR) was 56% (29/52) and was

238 The overall response rate for patients with IMT (treated

239 istency across study results (I = 98.3%) and the overall response rate was low.

240 The overall response rates at 6 months were 80%, 87%, an

241 Results The overall response rates for patients with ALCL treate

242 The overall response rates in patients with PTCL and CTC

243 During 2009, 2011, 2013, and 2015, the overall response rates were 71%, 71%, 68%, and 60%,

244 The overall results demonstrated the possibility of a re

245 The overall results suggest that OPN facilitates WNV neu

246 The overall retention rate was 73.3%, and 417 students w

247 uter plexiform layer (S6 sector), as well as the overall retinal thickness (RT) (S3, N3, I3, S6, and

248 ion between relative binding free energy and the overall reversible covalent binding affinity using a

249 The overall risk among patients with current or prior HB

250 There was on average, a 9% increase in the overall risk of graft loss per hour increase in the

251 31 (58%) of 53 patients in the overall safety population died; no deaths were relat

252 o to five experimental treatments can reduce the overall sample size requirement by up to 30% compare

253 In the overall sample, a one-unit increase in perceived-str

254 The interrater reliability of the overall scale showed an ICC of 0.95 (95% CI, 0.96-0.

255 nt surface NH4(+),ads intermediates dominate the overall SCR reaction, especially for hydrothermally

256 ence and structure components by abstracting the overall secondary structure into smaller substructur

257 techniques are employed in order to analyze the overall selectivity.

258 However, the overall sensitivity of in vivo confocal microscopy f

259 The overall sensory acceptance of GF mini sponge cakes w

260 irs for an RNA fold and thus also determines the overall shape and function of an RNA.

261 One of the key findings of our study is the overall shift toward excitation in liver-related hyp

262 The overall similarity of the skull shape of some dog br

263 tures demonstrate that A(+) not only affects the overall solid-state packing of the Th-nitrato comple

264 In our simulations, cholesterol reduces the overall solubility of oxygen within the membrane but

265 this eliminative coupling is stereospecific, the overall stereochemical outcome can be understood and

266 This review focuses on the overall strategies which can improve the selectivity

267 learning, there was a profound reduction in the overall strength and number of inhibitory connection

268 y quality, and the investigator group graded the overall strength of evidence using standard criteria

269 ewed, there has been no attempt to summarise the overall strengths and limitations of these scores fo

270 ars rates tend to decline from 1990 to 2013, the overall stroke burden in terms of absolute number of

271 he observed mutations are unlikely to affect the overall structural integrity and that they therefore

272 pectin complexes is discussed in relation to the overall structure and the charge density profile of

273 The overall structure consisted of a high electron densi

274 absence of ubiquitin or substrate liposomes, the overall structure of the C-terminal domain is in goo

275 ats (n = 1, 4) and the consequent changes in the overall structure of the RNA and DNA duplexes.

276 rd CDR3beta residue can effectively modulate the overall structure of, and Ag recognition by, human i

277 ural components relative to one another, and the overall structure similarity of the query protein to

278 ntion was performed in 235 patients (71%) of the overall study population.

279 The overall study prevalence of Salmonella in cats (3 of

280 The overall survey response rate was 38.1% (1793/4707) a

281 type of fractionation and treatment effect, the overall survival benefit being restricted to the hyp

282 Although the overall survival of children with solid tumours is 7

283 Although the overall survival of FL patients has recently improve

284 easome inhibitors (PIs) has greatly improved the overall survival of patients with MM.

285 The overall survival to hospital discharge after OHCA tr

286 t any clonotype representing more than 2% of the overall TCR population.

287 ith varying crystallographic orientations on the overall thermal boundary conductance.

288 f the number and duration of forays) but not the overall time spent in littoral regions.

289 Our results showed that the overall timecourse of adaption was similar in both H

290 To obtain the overall toll of killings and kidnappings, those prob

291 , representing a much larger contribution to the overall toxicity burden than VOCs or any aquatic emi

292 Furthermore, this study also highlights the overall transcriptomic control of the plant defense

293 We analysed both the overall trial population and a subgroup of patients

294 In the overall trial population of 940 patients, 5 year ove

295 ate and was approximately 5-fold faster than the overall turnover.

296 To control the overall type I error rate at 0.05, a hierarchical te

297 LS and global CS by 2DST and 2DTagg confirm the overall validity of 2DST strain measurement.

298 d inventories of emissions by characterizing the overall variability in emission magnitudes and the c

299 tly the faster state is accessed, the higher the overall velocity of the IFT train.

300 The overall-water-splitting with 10 mA cm(-2) at a low v