ライフサイエンスコーパス: the postulated

1 The postulated 1,2-phenyl shift as origin for the side r

2 The postulated actin-binding region of MARCKS, which inc

3 CMV protease provides a better definition of the postulated active site cavity and reveals an elastas

4 d that two conserved aromatic amino acids in the postulated active site region could be altered witho

5 mutant L483Y, known to lack desensitization, the postulated active state of the LBD dimer is indeed t

6 er than that for endogenous adenosine due to the postulated additional endothelial dilator.

7 s of expression are clustered on one side of the postulated alpha-helical structure.

8 ur rows of bristles on the scutum resembling the postulated ancestral one.

9 delocalization depends on the degradation of the postulated anchor protein(s) by the McsA-McsB-(ClpC

10 mmunoprecipitation experiments, we confirmed the postulated APP-FE65 and the LRP-FE65 interaction.

11 y a physical interaction between RNase P and the postulated archaeal exosome, a connection that has n

12 l data suggest these nuclei might constitute the postulated attractor-path integration mechanism, and

13 ts with primary biliary cirrhosis (PBC), but the postulated autoimmune mechanisms behind these condit

14 Consistent with the postulated autoinhibitory role of the JMD Tyr-559 an

15 eling studies and the successful trapping of the postulated azomethine ylide and azaquinone methide i

16 roism spectrum of Jun a 3 is consistent with the postulated beta-sheet core.

17 bserved location thus would be favorable for the postulated binding of E7 to phosphatidylethanolamine

18 switches in this system, are consistent with the postulated biological function of the SdiA protein a

19 within the highly conserved CHAE sequence of the postulated C-terminal deaminase catalytic domain des

20 atous plaque through a biological mechanism, the postulated capability to reduce or inhibit restenosi

21 ucture, in complex with citric acid bound in the postulated carbamoyl phosphate binding site, was det

22 d N170 in addition to concerted movements in the postulated carboxyl binding pocket that might allow

23 that any temperature-dependent alteration of the postulated cell matrix does not significantly affect

24 The postulated cellular mechanisms underlying the positi

25 We demonstrate that the postulated central binding domain surrounding layer

26 for hydroxyls on the lunar surface, and (ii) the postulated chondritic lunar water is not retained in

27 However, the postulated clear functional separation of rhythm- ve

28 DP-glucose dehydrogenase rather than through the postulated competing pathway leading from glucose 6-

29 complex has been studied in connection with the postulated contribution of short hydrogen bonds to b

30 A study of reaction orders supports the postulated cooperative catalysis.

31 05 and 1.10 angstroms unambiguously identify the postulated covalent carbinolamine and Schiff base in

32 However, lysine 155 is not required for the postulated covalent enzyme-substrate imine intermedi

33 hilicity of the functional group involved in the postulated cyclodecarbonation reaction and on solven

34 ergic inhibition in the PFC and suggest that the postulated deficit in GABAergic function in schizoph

35 The effect of the postulated deltaE(t) on fluctuations in the radiativ

36 th phosphoglycolohydroxamate, an analogue of the postulated DHAP ene-diolate intermediate.

37 The postulated differences in stimulant effect between c

38 a point inverse density weights derived from the postulated distance metric.

39 The functional role played by the postulated disulphide bridge in gamma-aminobutyric a

40 In addition, they formally prove the postulated downstream relationship of BMP4 with resp

41 e classified in 3 main families according to the postulated effect of exogenous boosting: 1) progress

42 The postulated effect of p65 on the JNK-mediated death-s

43 The postulated effect on orbital overlap may account for

44 and explained through the complex balance of the postulated electronic delocalizations.

45 cortin (Ucn), a Crh-related neuropeptide and the postulated endogenous ligand for Crhr2, is a potenti

46 Microarray analyses have led to the postulated existence and identification of numerous

47 ata support the idea that the Y5 receptor is the postulated 'feeding' receptor, and may provide a new

48 ng mode would place the C5 hydroxyl group of the postulated final intermediate distal to Fea and virt

49 on of Fl(red) with molecular oxygen restores the postulated Fl(N5[O]) via an unknown pathway.

50 Since the postulated function of HilD at the hilA promoter is

51 The postulated function of the Asp274-His32 diad is to h

52 The Mb diffusion data indicate that the postulated gel network in the cell must have a minim

53 Membrane-associated fragments within the postulated globular extracellular N-terminal domain

54 putative GTP-binding site is consistent with the postulated guanine specificity of the protein.

55 xual phenotype in sib pairs, we predict, for the postulated HD gene, a male thetamax as high as .254,

56 Overall, our findings support the postulated health benefits of fish consumption.

57 irudin-like region within the alpha subunit, the postulated high affinity binding site, direct bindin

58 The postulated high frequency and continent-wide geograp

59 The results suggest that the postulated homeostatic function of 5-HT2CR editing i

60 omic library of Mycobacterium bovis BCG with the postulated homologous domains from mycocerosic acid

61 wheel', with central or visceral obesity as the postulated hub of the wheel.

62 and one quinone (4-OBzl-1H-indole-6,7-dione, the postulated immediate precursor of the final blue dye

63 tion of primary accretion of the planets and the postulated impact origin of the Moon.

64 nt mutant, it should be possible to test for the postulated important roles for sulfolipids in the pa

65 peripheral blood leukocytes consistent with the postulated inflammatory function.

66 However, the postulated influence of pathogens on the filling of

67 instability, but the nature and magnitude of the postulated instability is a matter of conjecture.

68 the four stereoisomers of beta-Me(2')Nal in the postulated interaction site of the peptide inhibitor

69 this modelling framework we address whether the postulated interactions of the pathways and species

70 ) from singlet dioxygen (1O2*) and water via the postulated intermediacy of dihydrogen trioxide (H2O3

71 The electronic structure of the postulated intermediate is believed to lie between t

72 Further support for the postulated intermediates in the chemically challengi

73 nd chemical mechanisms and indicate which of the postulated intermediates in the latter will be detec

74 e, has repeatedly been proposed, but none of the postulated intermediates occurring after addition of

75 e PILs can select folding pathways featuring the postulated intermediates so that they are fully popu

76 in excellent agreement with model spectra of the postulated intermediates, supporting the proposed me

77 e extracted and compared to model spectra of the postulated intermediates.

78 ecular dynamics simulations, thus confirming the postulated intramolecular mechanism in atomic detail

79 athogenesis seems to be multifactorial, with the postulated involvement of the circulating fibrocytes

80 a useful reagent for experimentally probing the postulated involvement of virion surface proteins in

81 The trifluoromethanide anion is the postulated key intermediate in nucleophilic trifluor

82 statistical model to rank the performance of the postulated laws.

83 and with a bisubstrate inhibitor that mimics the postulated linear reaction intermediate.

84 Second, the postulated link between primary tumor size and emiss

85 At selected positions within the postulated lipid surface of the AChR, tryptophan sub

86 Our previous amino acid substitutions at the postulated lipid-exposed transmembrane segment M4 of

87 alphaCys222 is located in the postulated M1 transmembrane domain and predicted to

88 se fluorinated substrates is consistent with the postulated macrocyclization mechanism(s) en route to

89 Here, we show that the postulated macrotransposon can excise and reinsert e

90 enzyl cyanide as the second nitrile supports the postulated mechanism as well as the structure of der

91 To prove the postulated mechanism based on the participation effe

92 The postulated mechanism for the double-strand DNA break

93 The postulated mechanism is the activation of anorexigen

94 at is tethered to Ser195, in accordance with the postulated mechanism of action of this class of inhi

95 These results are consistent with the postulated mechanism of AGT repair that involves DNA

96 Our findings provide support for the postulated mechanism of O2(.-) activation at class I

97 The postulated mechanism of the cardiotoxicity is genera

98 re chlorophyll-a samples are consistent with the postulated mechanism.

99 This review will also discuss the postulated mechanisms associated with these drug-ind

100 One of the postulated mechanisms for the function of these prot

101 he C-terminal domain of the protein close to the postulated membrane-binding surface.

102 three molecules suggest a means for testing the postulated metabolic pathway.

103 ctional theory (DFT) calculations shows that the postulated Mn oxo active species, [Mn(O)(tpp)(Cl)] (

104 For example, the postulated mobile surface charges could be on an int

105 roximately 20 A from D1-Glu65 and D2-Glu312, the postulated network of hydrogen bonds must extend for

106 f the problem of serial order in behavior is the postulated neural representation of all serial eleme

107 sis of the DNA polymerase is consistent with the postulated nonthermophilic phenotype of these crenar

108 The postulated origins of the microwave-specific effect

109 a provide the first biochemical evidence for the postulated participation of the alpha-amino group in

110 To clarify the postulated pathway as mentioned in the literature, t

111 The postulated pathway of cGMP-dependent protein kinase

112 The postulated pathways involve initial proton abstracti

113 lation to the risk of in situ breast cancer, the postulated penultimate stage preceding invasive brea

114 electron demand created by rearrangement of the postulated peroxy intermediate.

115 hole at pH 10, which could be interpreted as the postulated pH-gating mechanism of AQP0-mediated wate

116 However in the same system the postulated Phe/Arg (i, i + 4) cation-pi interaction

117 ated isomerization product of CTC (iCTC) and the postulated photooxygenation product, bearing two oxy

118 In addition, we verify association of the postulated pore-forming protein CsoS1D with the carb

119 A cosmid containing the postulated pps gene cluster was identified by screen

120 rrier protein (ACP) to 3-methylcrotonyl-ACP, the postulated precursor of the cyclopropane ring of cur

121 se performed in rat and correlated well with the postulated presence of PV-1 in the endothelial diaph

122 The postulated principal mechanism underlying the benefi

123 he transition from the cleavage-competent to the postulated product release/transfer state may involv

124 sight may help explain the interplay between the postulated protective and pathogenic roles of PrP in

125 would be more stable toward hydrolysis than the postulated protonated imine in the enzymatic reactio

126 ) in the presumptive R7 cell and constitutes the postulated R1/6-to-R7 signal required in combination

127 The postulated radical mediated mechanism is supported b

128 directing conformational changes controlling the postulated rate-limiting product release step, even

129 The results were compatible with the postulated reaction mechanism, in which NAD(+) initi

130 im of proving the biochemical feasibility of the postulated reaction, we have heterologously expresse

131 The postulated reactive intermediate, a terminal alpha-o

132 ounds synthesized by us and others confirmed the postulated reactivity.

133 The postulated relation between silicone breast implants

134 a stronger quantitative basis for addressing the postulated relation, we applied several techniques o

135 The postulated relationship between the two proteins inv

136 The postulated relationship has not been proven, however

137 nm in venous erythrocytes, incompatible with the postulated reservoir function of SNO-Hb.

138 We question whether the postulated revenge and forgiveness systems constitut

139 ossible link between prebiotic chemistry and the postulated RNA world is discussed.

140 pY are not identical to those of dsRBDs, as the postulated RNA-binding site in pY does not coincide

141 e findings of this study are consistent with the postulated role for caveolin as a regulator of cellu

142 n the CRM1 RNA export pathway analogously to the postulated role for Dbp5p in yeast mRNA export.

143 These results support the postulated role of altered aversive conditioning in

144 protein levels of PHAVOLUTA, consistent with the postulated role of AMP1 in miRNA-controlled translat

145 Lp(a) and vascular accumulation, supporting the postulated role of apo(a) LBS in this potentially at

146 This function would be consistent with the postulated role of BRCA1 as a caretaker gene in pres

147 cell-substrate attachment is consistent with the postulated role of caveolin-1 in positively regulati

148 Consistent with the postulated role of CES-1 as an antiapoptotic transcr

149 This result is consistent with the postulated role of Cys-276 as a catalytic residue an

150 Focusing on the postulated role of epigenetic factors in the aetiopa

151 clin D1 gene expression has implications for the postulated role of ERbeta as a modulator of the prol

152 The results also confirm the postulated role of His-178 in binding the phosphate

153 The postulated role of infection in the causation of chi

154 this and other studies significantly weaken the postulated role of rivers as major drivers of Amazon

155 nes that have lost the mutant allele support the postulated role of SAMD9L in the regulation of cell

156 others discussed below are in agreement with the postulated role of the adjacent aspartates in the ca

157 In accordance with the postulated role of the caveolin-1 scaffolding domain

158 aemodynamic changes such as diaschisis or to the postulated role of the cerebellum in motor skill lea

159 The postulated role of the invariant Glu-235 is to ion p

160 e interaction with the receptors, similar to the postulated role of the N-terminal domain of CheR.

161 There is a considerable controversy about the postulated role of the Thr(671)-Leu(690) (peptide A)

162 e observed in normal cells may be related to the postulated role of this DNA repeat in position effec

163 ease with aging, an unexpected finding given the postulated role of this enzyme in repairing age-dama

164 dence induced by 4-hydroxyestradiol supports the postulated role of this metabolite in hormone-associ

165 This is consistent with the postulated role of this residue as essential for mai

166 mas-disrupted mutant should allow testing of the postulated roles of mycosides in pathogenesis.

167 An anatomical basis was sought for the postulated roles of nitric oxide (NO) as a labile tr

168 and M. leprae, it should be possible to test the postulated roles of these unique lipids in tuberculo

169 ies with respect to the structure as well as the postulated roles of this metalloenzyme in host-patho

170 f human SRAP and found that it does not have the postulated RRM (RNA recognition motif).

171 Here, we show that the postulated sensory Loop of the MEM domain plays an i

172 in integrating serine/threonine kinases into the postulated signaling pathways activated by hematopoi

173 mucoid qualifies as a preferential probe for the postulated small pore system, our results are discus

174 midzone MAPs may be one molecular basis for the postulated spindle matrix.

175 Changes of the DB sequence without affecting the postulated stem structure led to drastic losses of t

176 structures, thus confirming the presence of the postulated stem-loop, while all the bases in the loo

177 ay involve conformational changes other than the postulated switch to a genu-linear state.

178 Mutations in the postulated target site alter viral sensitivity to in

179 tudies provide a three-dimensional model for the postulated ternary cleavable complex of topoisomeras

180 after dose escalation was 331 ng/mL, within the postulated therapeutic range.

181 ound at all the nucleophilic 3' ends used in the postulated transesterification step.

182 e-5'-phosphate decarboxylase in complex with the postulated transition state analog, 6-hydroxyuridine

183 s: PB2-T1 ends at Pro466, on the boundary of the postulated transmembrane domain, and PB2-T2 ends at

184 A model of the postulated TSOX adduct suggests that it is stabilize

185 The postulated units express the spontaneous dynamics of

186 her, these results suggest that, contrary to the postulated universal corepressor role, CtIP activate

187 differentiation in a manner consistent with the postulated UPB1 function.