ライフサイエンスコーパス: the presumed

1 Conical intersections corresponding to the presumed 1,2-hydrogen shift and 1,2-alkyl shift to g

2 ned, however, in part because only 40-60% of the presumed 700-1,000 proteins involved in mitochondria

3 The presumed ability of these CD4-based BiKEs to bind al

4 riants involving the His-509-Glu-514 dyad as the presumed acid-base catalyst.

5 rotein kinases, and the second N terminal to the presumed activation loop located between subdomains

6 Distal chemical shift changes involving the presumed active site cover imply indirect conformati

7 One of the presumed advantages for using VSV as an oncolytic vi

8 n reflecting affective negativity) simulated the presumed affective state of the target person.

9 +) breast cancer (BCa) treatment is based on the presumed aggressiveness and likelihood of cancer rec

10 hydrophobic patch in the domain opposite to the presumed ALK4 binding site.

11 ferent paths with respect to the geometry of the presumed alkene radical cation intermediate.

12 azosin was given with phenylephrine to block the presumed alpha-1 agonist effect of phenylephrine.

13 ered viruses suggested that the structure of the presumed alpha-helical structure and positioning of

14 Biotic pollination is the presumed ancestral condition, but this key element o

15 al phenomena, a significant mismatch between the presumed and actual scale of ecological data may ari

16 ical scans, and the spatial concordance with the presumed and invasively defined seizure onset zone w

17 ght be exactly the ones to benefit most from the presumed antiarrhythmic properties of ranolazine.

18 as unevenly distributed, particularly around the presumed apex of the cone.

19 providing approximately 14-fold coverage of the presumed approximately 1.48-Gb genome.

20 lder mono- and bis-cycloadducts derived from the presumed aryne intermediates in high yield.

21 alse-negative rate that was close to that of the presumed background rate of latent tuberculosis infe

22 ation flow between the brain and spinal cord-the presumed basis of ensuing clinical impairment.

23 The presumed benefits of valve surgery remain unproven d

24 nion based on its orientation with regard to the presumed binding mode of aristolochene.

25 ABA(A) receptors, and point mutations around the presumed binding pocket were introduced into GLIC an

26 The presumed biogenesis of these RNAs involves a non-can

27 Although the presumed biological function of RNAP pausing is to a

28 ities of the WH2 domains do not reconstitute the presumed biological function of the full-length prot

29 in catalytic efficiency for the excision of the presumed biological target (paired with T) relative

30 and determinant of free leptin index (FLI), the presumed biologically active form of leptin.

31 ng expansion strategy designed to complement the presumed biosynthesis of this complex meroterpene.

32 pected apparent size of the event horizon of the presumed black hole, suggesting that the bulk of Sgr

33 immediately adjacent to the tnaC stop codon, the presumed boxA and rut sites, contributed most signif

34 The presumed broad tropism of poxviruses has stymied att

35 d with a particulate steroid suspension, and the presumed but not proven mechanism is embolization an

36 This model identifies that the presumed C-terminal transmembrane helix is buried wi

37 Surprisingly, we found that the presumed cancer-promoting gene TCF7L2 functions inst

38 ecretase activity without altering levels of the presumed catalytic component (PS) of the enzyme may

39 the H296A mutant, in which the side chain of the presumed catalytic His is removed, had a 6-fold drop

40 Binding of Sr(2+) to the presumed catalytic Pb(2+) site in the precatalytic l

41 formed aggregates, whereas an E72Q mutant in the presumed catalytic residue is much less active.

42 Notably, substitutions in the presumed catalytic triad of RsbQ also abolished the

43 ino acids in the signature, one of which was the presumed catalytic tyrosine, resulted in a 1,000-fol

44 The bacterium is the presumed causal agent of huanglongbing (HLB), one of

45 Searching for host nests is the presumed causal factor influencing cowbird Hp size,

46 sociated with a peripheral component in that the presumed causative agent, PrPSc, also accumulates in

47 Extensive strut malapposition was the presumed cause for ScT in 1 case.

48 psy, which revealed Exserohilum rostratum as the presumed cause of death.

49 In many cases, the microbiota is the presumed cause of the variation.

50 The normal germinal centre B cell is the presumed cell of origin for both BL and diffuse larg

51 ressed in interstitial cells of Cajal (ICCs)-the presumed cell of origin for GIST-as well as in haema

52 ha-/- mice despite the continued presence of the presumed cervical cancer precursor cell type, reserv

53 and NCOs are strongly modulated in trans by the presumed chromatin remodelling protein PRDM9, and in

54 The tetrad Arg-Ala-Lys-Arg is the presumed cleavage site in the gPr73env precursor, an

55 In those cases, UHR OCT suggested that the presumed clinical diagnosis was incorrect and favore

56 igmaU activity caused by disruption of rsuA, the presumed cognate anti-sigma factor of sigmaU.

57 RitR is phosphorylated in vitro by StkP, the presumed cognate kinase of PhpP, and the site on Rit

58 g helix alpha4' in the C-terminal domain, of the presumed common ancestor of cytosolic GSTs (i.e. glu

59 t the exact mode of uPAR/uPA interactions or the presumed conformational changes that accompany uPA/u

60 ongener patterns similar to those of salmon, the presumed contaminant source.

61 o reconcile this transient mRNA profile with the presumed continuing "need" for TTP protein, for exam

62 Cortex of posteromedial HG, the presumed core of human auditory cortex, represented

63 of a seed molecule, a stabilized version of the presumed critical nucleus, removes the kinetic barri

64 e inhibitor occupies both the glutamate- and the presumed cysteine-binding site and disrupts the prev

65 A receptor in which the presumed cytoplasmic signaling C-terminal tail of FP

66 ns that were transmitted account for 6.8% of the presumed de novo mutations in the children.

67 ancer death associated with screening during the presumed detectable preclinical phase was 0.26 (95%

68 In humans, the presumed detrimental role of a heightened blood CRP

69 d electrical stimulus was increased, despite the presumed disappearance of an SDP in the post-AP peri

70 3 Mb deletion whose proximal region contains the presumed disease-associated gene TBX1 (T-box 1).

71 n's disease (PD) is still controversial, yet the presumed dopamine toxicity is partly responsible for

72 rmore, we sought to detect the expression of the presumed downstream targets of PTEN, such as P-Akt,

73 d "modulators") far outnumber the RL inputs (the presumed "drivers").

74 press wild-type and mutant forms of Lamin C (the presumed Drosophila A-type lamin), in an otherwise w

75 result, the electrostatic environment along the presumed electron transfer path is substantially dif

76 were performed with dihydroxyacetone (DHA), the presumed endogenous substrate for FSA, as well as hy

77 n with a sister history of breast cancer and the presumed enrichment of shared environmental and gene

78 Using chemical complementation with SeMM, the presumed enzymatic product of MMT, we restored the c

79 Glutaconyl-coenzyme A (CoA) is the presumed enzyme-bound intermediate in the oxidative

80 c) ovules (41-89%) in tetraploid F1s despite the presumed equal genetic contribution from the diplosp

81 s recorded in the LL firing maximally within the presumed ethological ITD range.

82 distinct lesion was seen endoscopically but the presumed etiology was an unidentified vascular malfo

83 Despite the presumed evolutionary advantages associated with ful

84 the broad molar mass distribution (MMD) and the presumed existence of different end group functional

85 quences were identified, and for 75% of them the presumed expression pattern was confirmed by Norther

86 he binding site, in which re-entrant loop 2, the presumed extracellular gate for the substrate bindin

87 combined test localizations were compared to the presumed EZ and to the postsurgical outcome.

88 n linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December

89 r storage polysaccharide in this species and the presumed food of H. hampei.

90 r led to a possible catalytic cycle based on the presumed formation of an acylborate intermediate.

91 Injection of a peptide corresponding to the presumed fourth intracellular loop of the transporte

92 with large complex carbohydrates, reflecting the presumed function of DPE2 in vivo.

93 Based on the presumed function of homologous genes involved in th

94 So, is the presumed functional hierarchy in FEF an intrinsic pr

95 unwind DNA suggest that these two members of the presumed functional replisome may act synergisticall

96 ion of Arg18 is more optimally positioned at the presumed gamma-phosphate location of ATP, close to t

97 nterneurons, what might be of importance for the presumed gating function of PRC in normal and diseas

98 Despite numerous mutagenesis studies, the presumed general base, whose role is to activate hyd

99 SP-6 targeted to a membrane-distal region of the presumed glycocalyx rolled more like leukocytes: rol

100 The presumed ground state of a nematic fluid confined in

101 In the process of reviewing the presumed healthy PGP-10 genomes, we find numerous li

102 The presumed helices are comprised of hydrophobic residu

103 Several formulations for the presumed heme-Fe{N(2)O(2)}(n-) intermediates have be

104 yces cerevisiae Mcm7 protein is a subunit of the presumed heteromeric MCM helicase that melts origin

105 The presumed hexaploidization event occurred after the A

106 ppreciable activation of alpha4beta2 nAChRs, the presumed high-affinity nAChRs in rodent brain.

107 on, this receptor is the only GPCR for which the presumed higher order oligomeric state in native mem

108 Moreover, the presumed Hox target genes are predominantly situated

109 introgression between these species, and for the presumed hybrid origin of I. nelsonii.

110 The presumed hydrazine-FeMo-cofactor adduct displays a r

111 One negative outcome can be the presumed identification of peptides that do not exis

112 ated is used as a metric of plausibility for the presumed identification.

113 This suggests that the presumed immune tolerance in chronic HBV infections

114 Because of the presumed importance of ChBF regulation for maintenan

115 eparin (LMWH) during PCI has been limited by the presumed inability to monitor its anticoagulant effe

116 aracterized the distribution of ferroportin, the presumed intestinal iron exporter, and have evaluate

117 were mutated to cysteine, one at a time, in the presumed intracellular end of the first transmembran

118 nnecting TM1 to TM2 (Leu(277)-Arg(287)), and the presumed intracellular end of TM2 (Ala(288)-Ala(291)

119 ments suggest that the effective charge near the presumed intracellular mouth of the pore is critical

120 The presumed involvement of paired box gene 5 (PAX5) in

121 oline substitution at residue 419 (A419P) of the presumed ion channel TRPML3.

122 d with each other and that were aligned with the presumed isofrequency axis of the central nucleus of

123 The presumed junction between the precursor and the proc

124 ans-5-OH-TBOH to dehydrate at all pH values, the presumed kinetically controlled yield of 17alpha-TBO

125 We investigated whether the presumed lack of transmission of serotype 11E is con

126 As a consequence of the presumed lack of ZMPSTE24 activity, prelamin A, the

127 The presumed [LCo-H](+)-intermediate, especially when L

128 se and SM1 presumably competes with enolase, the presumed ligand, for binding to a putative midgut re

129 share several conserved residues, including the presumed ligands for the Mg(2+) and a catalytic hist

130 to epoxidize linalool, a model substrate for the presumed linear polyketide intermediate in monensin

131 c surface of the endoplasmic reticulum (ER), the presumed locale of channel synthesis.

132 After responsive animal sampling in the presumed location of exposure, cattle and/or buffalo

133 Based on the presumed location of K33 at or near the luminal doma

134 ) is located near the end of each S6 domain, the presumed location of the activation gate.

135 e neuroimaging techniques were compared with the presumed location of the epileptogenic zone (PEZ) as

136 pted, with one component blue shifted due to the presumed loss of an H-bond donor and the other red s

137 stood but is expected to be large because of the presumed low tolerance of deep-sea taxa to environme

138 The effect of RT in the presumed low-risk luminal A-like tumors was excellen

139 s share the same centric fusions relative to the presumed macropodid ancestral karyotype, but can be

140 oning, we showed that the largest subunit of the presumed maize Pol IV is involved in paramutation, a

141 expectedly high frequency in regions lacking the presumed mammalian "targets," suggesting that mammal

142 The presumed maternal inheritance in angiosperms allows

143 The presumed mechanism behind this association suggests

144 The presumed mechanism for this effect is inhibition of

145 acological treatment options with respect to the presumed mechanism of action and its role in DCI.

146 Despite the therapeutic promise, the presumed mechanism of action of donor cell populatio

147 Inhibition of pro-survival pathways, the presumed mechanism of CAL-101, does not explain this

148 In two additional specimens, simulation of the presumed mechanism of fifth metatarsal bone fracture

149 in process variables (variables that reflect the presumed mechanism of treatment), and monitoring dif

150 why intraspecific competition should not be the presumed mechanism underlying density-dependent habi

151 elected biomarkers, which is consistent with the presumed mediation hypothesis.

152 halomyelitis (EAE) in laboratory animals and the presumed mediators of multiple sclerosis in humans.

153 alkaline treatment, which is consistent with the presumed membrane localization.

154 from the microanalytical results; otherwise, the presumed metal-core composition would have been (mu(

155 verexpression is difficult to reconcile with the presumed mitochondrial matrix localization for endog

156 found within the dLGN in that the RS inputs (the presumed "modulators") far outnumber the RL inputs (

157 a) is highly expressed in adipose tissue and the presumed molecular target for antidiabetic thiazolid

158 e pentameric form of PLB, despite the use of the presumed monomeric I40A mutant.

159 ase with a synthetic pentaketide analogue of the presumed monomeric polyketide precursor of elaiophyl

160 ects required significantly higher titers of the presumed more virulent FSS13025 Cambodia (ZIKV(C)).

161 romuscular junction (NMJ), only about 32% of the presumed motor axon terminals in the ventral horn ex

162 We propose that the presumed multiple effects of Nampt/PBEF/visfatin may

163 stent vegetative state, less apprehension of the presumed mysteries of legal proceedings, and greater

164 CD9 levels may serve to distinguish between the presumed MZ precursor B cell population in the splee

165 rotein may serve as an additional marker for the presumed MZ precursor population of splenic B cells.

166 e presented rearrangement reaction, in which the presumed N-acylated intermediate reacts intramolecul

167 ysteines engineered to positions external to the presumed narrow region (e.g., 334, 335, and 337 in T

168 orm intramolecular G-quadruplexes, which are the presumed natural substrates for the G-quadruplex hel

169 Thus, despite the presumed need to recognize a similar range of antige

170 quadruplex DNA structures in genomic DNA and the presumed need to resolve these structures for DNA re

171 The assay's specificity among the presumed negative American donor samples was 100% (9

172 an unexpected relationship between AP180 and the presumed non-neuronal homologue CALM.

173 The presumed nonenzymatic hydrolysis of N-propargylimino

174 e that have not been dated by tuning them to the presumed Northern Hemisphere signals.

175 Here, we examined the presumed nucleosome remodeling activity of Lsh on ch

176 copy-number plasmid carrying POL30, despite the presumed occurrence in the mutant of sliding clamp a

177 of alternative social organizations involves the presumed odorant-binding protein gene Gp-9 in fire a

178 To decipher the presumed oncogenic mechanism of miR-125b, we used tr

179 enes encode neomorphic proteins that produce the presumed oncometabolite 2-hydroxyglutarate (2-HG).

180 were randomly assigned within 6 weeks after the presumed onset of infection to receive hyperimmune g

181 ice, and levels within the intestinal tract (the presumed origin of the gas) were four times greater

182 The presumed palaeotetraploidy of the American paddlefis

183 sum of pancreatic tissue area to the left of the presumed pancreatic transection site.

184 anomalies were considered in the context of the presumed pathogenetic mechanism related to the neuro

185 Only one of the presumed pathogenic mutations in the VSX1 gene, Asp1

186 Curves in the presumed penumbral regions (n = 8) showed varied mor

187 e reaction required for the isomerization of the presumed peroxynitrite intermediate to the product,

188 tron microscopy specimen protocol shows that the presumed phospholipid bilayer membrane ribbons that

189 her active sites but mirrors the geometry of the presumed phosphoryl transfer transition state.

190 hat begins to offer plausible mechanisms for the presumed physiologic effects of acupuncture.

191 ) nor peptidyl transferase center (PTC) RNA, the presumed physiological RNA substrate, favor oligomer

192 hat only His 339 and Asn 341 are proximal to the presumed position of the 4-OH leaving group.

193 n of the lever arm in a crystal structure of the presumed poststroke conformation of myosin VI.

194 not K-Cl cotransporter 2, are colocalized at the presumed postsynaptic sites.

195 monstrates that both prostate carcinomas and the presumed precursor lesion (high-grade prostatic intr

196 Barrett's esophagus is the presumed precursor lesion for this cancer.

197 on as a biomarker for infection persistence, the presumed precursor of HPV16-associated oropharyngeal

198 g prostatic intraepithelial neoplasia (PIN), the presumed precursor of human prostate cancer.

199 fide CCD, and is able to cleave zeaxanthin, the presumed precursor of saffron apocarotenoids, both i

200 d the adjacent epithelium from cystadenomas, the presumed precursor of SBTs.

201 have been identified, with cholesterol being the presumed precursor.

202 t to the site of vascular injury do not play the presumed preeminent role in supporting prothrombinas

203 temporal tip, accounting for half or more of the presumed premorbid volume, was unlikely to have cont

204 There was a high level of agreement between the presumed preoperative diagnosis and intraoperative d

205 ting carnivorous predators in green tissues, the presumed primary function of terpenoid volatiles rel

206 coincides with the location of nerve bundles-the presumed primary photoreceptors.

207 The amino-terminal 290 residues of UL44, the presumed processivity factor of human cytomegaloviru

208 PF-8, the presumed processivity factor of Kaposi's sarcoma-ass

209 The structure of the presumed product-bound state reveals that binding in

210 1) in primary human germinal center B cells, the presumed progenitors of HRS cells, upregulates disco

211 -negative/stx(2)(+) E. coli O157:H7 strains, the presumed progenitors of stx(1)(+)/stx(2)(+) E. coli

212 d IGF-I deprivation required the survival of the presumed progenitors.

213 rcept of the aura changed corresponding with the presumed propagation from the V1 to the V2 region of

214 And the presumed protective effect of obesity on osteoporosi

215 rly because longstanding hypotheses, such as the presumed protective effects of fruits, vegetables, a

216 ve to determine the type of parkinsonism and the presumed proteinopathy using specified criteria.

217 gional differences in neuronal properties of the presumed pyramidal cells were found between PrL and

218 eaction is inhibited by molecular oxygen via the presumed quenching of the photoexcited triplet state

219 Because of the presumed radical nature of the process, hindered ami

220 We noticed that the breakpoints of the presumed rearrangements were delineated by exon-exon

221 In both cases, the presumed receptor is cryptochrome, a protein thought

222 To identify the presumed receptor proteins, two-hybrid screening was

223 This mechanism is the presumed recognition step for the vesicular packagin

224 To date, little is known about the presumed redox activity of VIMP, its structure and h

225 hinery revealed similarities among sugars at the presumed reducing termini of these oligosaccharides.

226 otype T cells that includes cells expressing the presumed regulatory T cell marker, Foxp3.

227 The Mcm2-7p heterohexamer is the presumed replicative helicase in eukaryotic cells.

228 though 90% of isolates from the environment, the presumed reservoir for the majority of P. aeruginosa

229 lizes as stationary dots at the cell cortex, the presumed result of offloading in our model, as does

230 cated in three regions: the AUG start codon, the presumed ribosomal binding site region, and a region

231 rship interests have never been established, the presumed right of researchers and institutions to co

232 e although these residues were far away from the presumed RNA binding site in the crystal structure o

233 equence space would have been crucial during the presumed RNA world and confers selective advantage i

234 The presumed Robo ligands Slit2 and Slit3 are expressed

235 tion is inconsistent with published data and the presumed role of ABCC6, we performed experiments to

236 Given the presumed role of alpha cells to detect brisk transie

237 The presumed role of an overactive protein arginine deim

238 Furthermore, the presumed role of mTOR in hypertrophy is derived from

239 This might underscore the presumed role of the cerebellum as a state estimator

240 The presumed role of the primate sensorimotor system is

241 also for abiotic and biotic processes with, the presumed, same formal chemical degradation mechanism

242 elated maps had a degree of concordance with the presumed seizure onset zone for all patients.

243 nd the maps had a degree of concordance with the presumed seizure onset zone in 10 patients.

244 elated maps had a degree of concordance with the presumed seizure onset zone in six of eight patients

245 er was localizable at sub-lobar level within the presumed seizure onset zone in six patients.

246 ally significant haemodynamic cluster within the presumed seizure onset zone was between 1.1 and 3.5

247 that extracellular Mg(2+) signalled through the presumed sensor histidine kinase, CsrS.

248 tern of activity was the opposite of that of the presumed serotonergic cells.

249 -magnetic layers is typically ignored due to the presumed short range of such proximity effects.

250 cture of a cysteinyl-flavin covalent adduct, the presumed signaling species that leads to phototropin

251 amma-methylene-diphosphonate (GMP-PCP) (i.e. the presumed signaling-active state) and show that it is

252 iration and the pre-Botzinger complex (PBC), the presumed site for respiratory rhythm generation.

253 ts, pacing the high right atrial septum near the presumed site of Bachmann's bundle in sinus rhythm s

254 was traced with microsatellite markers from the presumed site of domestication to distant regions of

255 located at the preautophagosomal structure, the presumed site of double-membrane vesicle formation.

256 trafficking of coat protein to mitochondria, the presumed site of FHV assembly, and that this traffic

257 and decorrelation from the receptor array to the presumed site of odour learning, the mushroom body.

258 ssociated with ribosomal function, including the presumed site of peptidyl transferase activity in th

259 In 2012, a skeleton was excavated at the presumed site of the Grey Friars friary in Leicester

260 y integrated in the brain's central complex, the presumed site of the sun compass.

261 te circuitry in the brain's central complex, the presumed site of the sun compass.

262 bic channel of dihydroorotate dehydrogenase, the presumed site of ubiquinone binding during oxidation

263 sociated with puberty, self-evaluations, and the presumed social reorientation during the transition

264 ng adherence, drug susceptibility results of the presumed source case (if known), safety, cost, and p

265 The ventral tegmental area (VTA) is the presumed source of dopamine in the dorsal hippocampu

266 resumably chaotrope-induced deceleration and the presumed, square root-dependent ionic strength-induc

267 With FISH as the presumed standard testing method, the positive and n

268 ax than do K15- basal cells, consistent with the presumed stem cell nature of K15+ basal cells.

269 Tonically active neurons (TANs), the presumed striatal cholinergic interneurons, could be

270 r type of protecting group), a compound with the presumed structure of the natural product serratin w

271 lation of the A-ring 7-hydroxyl of daidzein, the presumed substrate for O-methylation, in vitro.

272 A fluorogenic peptide representing the presumed subtilase recognition site in AtRALF23 was

273 normal thalamic RSNs lend further support to the presumed subtle thalamic injury in patients with MTB

274 Studies are needed to confirm the presumed superiority of this method for diagnosing A

275 ral insertions led to elevated expression of the presumed target flanking genes.

276 ency at the rat serotonin 5-HT(2A) receptor, the presumed target for hallucinogenic agents, and a rec

277 n several RNA data sets, and the function of the presumed target gene was explored using an RNA inter

278 Much has been learned about the presumed target of acute stroke therapy, the ischemi

279 Whereas the presumed target of this inhibitor was rhodesain (als

280 s as the peptide moves on the access path to the presumed target, the inner membrane.

281 nvestigate the localisation and magnitude of the presumed tau Positron Emission Tomography (PET) trac

282 es such as tris(chlorophenyl)methane (TCPM), the presumed TCPM metabolite tris(chlorophenyl)methanol

283 ring the simulations shift the operators and the presumed termini of the loop.

284 This concept has been tested by replacing the presumed tetrahedral carbon of a thermolysin substra

285 tance to the active-site zinc ion, mimicking the presumed tetrahedral transition state.

286 The role of the presumed Th17 cytokine IL-26 in antibacterial host d

287 moters is well known to silence genes and is the presumed therapeutic target of methylation inhibitor

288 While the cages are the presumed thermodynamic sink, we experimentally demon

289 showed a gradient in dendritic length along the presumed tonotopic axis.

290 ent in temporal processing properties across the presumed tonotopic axis; neurons in the MSO and the

291 The presumed totipotency of plant cells leads to questio

292 This suggests that the presumed transglycosidases Dfg5 and Dcw1 of cdc1-314

293 ns flanking its B12 binding site even though the presumed transport site in the previously reported c

294 investigation into the nature and causes of the presumed underuse of epilepsy surgery and the elabor

295 We extend the basic models to show that the presumed unidirectional nature of the amplification

296 Consistent with the presumed use of a secretory pathway, both groups of

297 arliest tetrapods and raises questions about the presumed vertebral architecture of tetrapodomorph fi

298 Owing to the presumed weak influence of single genes on disease p

299 hereas an 8-bp deletion in the third exon of the presumed wild-type normal allele causes a frame-shif

300 gical variant of UL, may account in part for the presumed yet rare malignant transformation of UL to