ライフサイエンスコーパス: the risk for

1 roke) demonstrated that pioglitazone reduced the risk for a composite outcome of stroke or myocardial

2 ge might be associated with a 3% increase in the risk for a detachment (odds ratio, 0.97; 95% CI, 0.9

3 s well as cardiovascular events but increase the risk for a diagnosis of type 2 diabetes mellitus (T2

4 ity of fetal growth and development predicts the risk for a range of noncommunicable, chronic illness

5 wed with a protective mechanism that reduces the risk for aberrant recombinations and chromosomal tra

6 ocytes exposed to genotoxic stress increases the risk for aberrant recombinations.

7 Based on the available evidence, the risk for achieving a noncomplete mesorectal excision

8 Syphilis infection also increases the risk for acquiring or transmitting HIV infection.

9 owed 3 risk variants significantly increased the risk for ACT; namely ABCC2 rs8187710 (pooled odds ra

10 hout diabetes mellitus, pioglitazone reduced the risk for acute coronary syndromes after a recent cer

11 axis with daily colchicine or NSAIDs reduces the risk for acute gout attacks by at least half in pati

12 Induction immunosuppression decreases the risk for acute rejection and improves graft outcomes

13 ney-specific self-antigens that may increase the risk for acute rejection through unclear mechanisms.

14 pothesized to lead to amyloidosis increasing the risk for AD.

15 investigate whether maternal PCOS increases the risk for ADHD in the offspring.

16 The risk for ADHD was higher among obese mothers with PC

17 (ART) started before conception may increase the risk for adverse birth outcomes among women with hum

18 The risk for adverse events was low but greater among ol

19 ent operations were not detected to increase the risk for adverse outcomes.

20 rvational Study (TOCOS), we assessed whether the risk for adverse pregnancy outcomes is associated wi

21 r, or anxiety disorders in general, increase the risk for adverse pregnancy outcomes.

22 The risk for AF conferred by genomic variation is simila

23 rmonal flux, including pregnancy, exacerbate the risk for affective disturbance and promote hypothala

24 a have additive or multiplicative effects on the risk for airflow obstruction, but this has not been

25 ion of the pleiotropic genes contributing to the risk for alcohol dependence commonly expressed by fo

26 vidence that maternal BBP exposure increases the risk for allergic airway inflammation in the offspri

27 transplant recipients is limited because of the risk for allograft rejection and poor tolerability.

28 transplant recipients is limited because of the risk for allograft rejection and poor tolerability.

29 trenuous physical activity (PA) may increase the risk for ALS.

30 To determine the risks for altered cytogenetic profile based on melan

31 To characterize and quantify the risk for Alzheimer-related cognitive decline among c

32 e, we explored the possibility of predicting the risk for AMR by measuring mRNA transcripts of AMR-as

33 The risk for an abnormal cervical cytology result was lo

34 A previous episode of anaphylaxis increased the risk for anaphylaxis in SCIT (OR [95% CI] = 17.35 [1

35 The risk for and consequences of recurrent mitral regurg

36 concentrations of MMP-8 are associated with the risk for and outcome of cardiovascular diseases (CVD

37 endarterectomy, a harm of screening included the risk for angiography prompted by abnormal results on

38 uman genetic variation in the eCB system for the risk for anxiety and consequences of stress across d

39 The risk for any adverse birth outcome was lower among i

40 pecific whereas the other four loci increase the risk for any food allergy.

41 The risk for any fracture at 10 years was 156.8 events p

42 ups, rivaroxaban use significantly increased the risk for any major bleeding when compared with warfa

43 ach percentage point increase in mean HbA1c, the risk for any-CVD and for MACE increased by 31 and 42

44 The C-G-T haplotype increased the risk for ARC overall (P = 0.005, OR = 1.8), and both

45 meters between men and women that may affect the risk for arrhythmias.

46 tatins (RR, 0.75; 95% CI, 0.70-0.81) reduced the risk for ASCVD.

47 o antidepressants could have a major role in the risk for ASDs.

48 elated with the severity of inflammation and the risk for asthma attacks.

49 polymorphisms (SNPs) that modestly increase the risk for asthma.

50 ce whole-blood 5-HT levels and may influence the risk for autism spectrum disorder (ASD).

51 The risk for autochthonous CHIKV transmission under rece

52 However, little is known about the risk for autoimmune disorders among individuals with

53 The risk for bias was assessed as low in 10 studies, hig

54 f population regions, pioglitazone increased the risk for bladder cancer could be found in European p

55 the antidiabetic drug pioglitazone increases the risk for bladder cancer.

56 ding the alpha5 nAChR subunit, that increase the risks for both smoking and schizophrenia.

57 Regular aspirin use was not associated with the risk for breast, advanced prostate, or lung cancer.

58 te- to high-intensity statin therapy lowered the risk for CAD and mortality by 44%.

59 The risk for CAMR is low in patients with no DSA even if

60 ministration of FTY720 potentially increases the risk for cancer in recipients.

61 s no relationship (beneficial or harmful) to the risk for cardiovascular and cerebrovascular disease,

62 The aim of this study was to assess the risk for cardiovascular disease (CVD) with ISH in yo

63 yceride (TG) levels are well-correlated with the risk for cardiovascular disease (CVD).

64 tulated that PD could be causally related to the risk for cardiovascular disease, a hypothesis tested

65 We also noticed that the risk for cardiovascular events increased with increa

66 in NOD2 with current smoking in relation to the risk for CD (frameshift variant fs1007insC; rs574329

67 with cow's milk-based formula would decrease the risk for celiac disease later in life.

68 The risk for CHIKV transmission was the combination of t

69 include finding genes that cause or increase the risk for childhood and adult-onset diseases, finding

70 with prenatal stress is reported to increase the risk for children to develop autism spectrum disorde

71 The risk for chronic kidney disease (CKD) among obese pe

72 embrane channel-like 4 gene (TMC4) increased the risk for cirrhosis in alcohol abusers.

73 development of lymphocytes, while minimizing the risk for collateral damage.

74 Diet, however, can also decrease the risk for colorectal cancer and be used as a chemopre

75 f inflammatory bowel disease (IBD) increases the risk for colorectal cancer.

76 The risk for complications should be carefully balanced

77 ociations between 25(OH)D concentrations and the risk for concurrent sensitization at age 0.5, 2, and

78 ncy generally does not meaningfully increase the risk for congenital malformations overall or cardiac

79 d processing in the NAcc, which may increase the risk for continued drug use and later addiction.

80 ed with placebo, BP-lowering therapy reduced the risk for coronary heart disease (RR, 0.84; 95% CI, 0

81 mon genetic variants at the CXCR4 locus with the risk for coronary heart disease, along with CXCR4 tr

82 r percutaneous coronary intervention reduces the risk for coronary thrombotic events (CTEs) at the ex

83 Factors increasing the risk for CR-POPF development included increasing Fis

84 te, frontal T axis, and QT interval assesses the risk for CVD and compares favorably with the FRS alo

85 ment tool that allows physicians to estimate the risk for CVD events following OLT.

86 The association between sedentary time and the risk for CVD is nonlinear with an increased risk onl

87 lysis, HIV infection significantly increased the risk for death among all women (hazard ratio, 1.95;

88 When the risk for death was accounted for, there were 6.1 (CI

89 ratio (HR) or odds ratio were used to assess the risks for death, readmission, and device-related com

90 interaction between education and income in the risk for dementia in China.

91 The risk for dementia is strongly modulated by type of m

92 r depressive symptoms in adulthood increases the risk for dementia remains the subject of debate.

93 hypothesis that depressive symptoms increase the risk for dementia.

94 even when chronic/recurring, do not increase the risk for dementia.

95 ether ADHD medication increases or decreases the risk for depression.

96 berculosis (TB) and transcripts that predict the risk for developing active TB in humans, the early t

97 ls 2 (TREM2) were recently found to increase the risk for developing Alzheimer's disease (AD).

98 ppropriate secretion of aldosterone increase the risk for developing cardiovascular disease; however,

99 ropsychiatric diseases at a young age affect the risk for developing dementia.

100 the innate immune system greatly influences the risk for developing metabolic complications associat

101 ndividuals disturbs sleep and might increase the risk for developing mood disorders.

102 ating agents to treat patients with AID with the risk for developing myeloid neoplasm.

103 potential risk factors were used to examine the risk for developing nonaffective psychoses.

104 relating to cognitive deficits that increase the risk for developing psychotic symptoms and the latte

105 t into how a history of infection can impact the risk for developing recurrent infection and has impl

106 protein (Mttp) causes hepatic steatosis, yet the risks for developing hepatic fibrosis are poorly und

107 o determine how sex and APOE genotype affect the risks for developing MCI and AD.

108 ariations play a critical role in increasing the risk for development of common complex diseases, and

109 Only when such data are available can the risk for development of resistance be gauged appropr

110 lation of T cell responses, and subsequently the risk for development of T1D.

111 The risk for diabetes after starting antipsychotic treat

112 rd ratio, 3.44; 95% CI, 1.73-6.83) increased the risk for diabetes without a statistically significan

113 ABSTRACT: The risk for diastolic dysfunction increases with advanc

114 ase onset; however, blood presence increased the risk for disease development (relative risk/positive

115 re, this new vaccine candidate may not carry the risk for disease enhancement associated with Ab-base

116 The risks for disease progression and death significantl

117 o reduce the risk of subsequent PE, increase the risk for DVT, and have no significant effect on over

118 a A(H1N1) vaccination in pregnancy increases the risk for early childhood morbidity in offspring.

119 To search for rare variants contributing to the risk for EOAD.

120 However, neither medication reduces the risk for estrogen receptor-negative breast cancer or

121 or modulators that have been shown to reduce the risk for estrogen receptor-positive breast cancer an

122 After multivariate analysis, the risk for events was significantly associated with th

123 ed to detect a moderate riluzole effect, and the risk for exaggerated placebo responses was mitigated

124 prolonged mechanical ventilation, increasing the risk for failed liberation from ventilatory support.

125 patients with comorbidity had around 4 times the risk for fatal infection than those without (adjuste

126 III disrupted normal metabolism and elevated the risk for fatty liver disease in mice maintained on a

127 However, the risk for fracture is also higher.

128 among patients at higher risk but increased the risk for fracture more.

129 d colorectal cancer (CRC) but also increases the risk for gastrointestinal (GI) and cerebral hemorrha

130 The risk for graft rejection after DMEK is low, and an e

131 an selection, desensitization, and assessing the risk for graft rejection.

132 iving after an ICD shock was estimated using the risk for harm (RH) formula, and an annual RH of less

133 Prophylaxis reduced the risk for HBV reactivation (OR, 0.12 [95% CI, 0.06 to

134 onic HBV receiving solid tumor chemotherapy, the risk for HBV reactivation is similar to the risk wit

135 The risk for HCC decreased significantly 2 years after S

136 re, practitioners also need to be mindful of the risks for HCV reinfection and educate patients on pr

137 of PPIs in patients with cirrhosis increases the risk for HE; risk increases with dose.

138 ges in body composition over time may affect the risk for heart dysfunction more precisely than the c

139 ntribute to steatohepatitis, which increases the risk for hepatitis C virus (HCV)-associated hepatoce

140 of hepatitis C virus (HCV) infection reduces the risk for hepatocellular carcinoma (HCC), but a risk

141 Sitagliptin use does not affect the risk for hHF in T2DM, both overall and among high-ri

142 The risk for hHF was not higher with DPP-4 inhibitors th

143 ate, zoledronic acid, or denosumab to reduce the risk for hip and vertebral fractures in women who ha

144 The risk for HIV-associated opportunistic infections inc

145 0416), but on-treatment analysis showed that the risk for hospitalized gastrointestinal bleeding was

146 ng trials produced conflicting results about the risk for hospitalized heart failure (hHF) associated

147 ther studies are needed to better understand the risk for HPV infection among male virgins.

148 and exhibition swine is central to assessing the risk for human infections with variant viruses, incl

149 ffect of hydration during STEC infections on the risk for HUS.

150 Among once-weekly GLP-1RAs, the risk for hypoglycemia was similar, whereas taspoglut

151 improved glucose tolerance did not increase the risk for hypoglycemia, nor did it rely upon hyperins

152 tors of serotonin reuptake actually increase the risk for ICH and the effect of concomitant use of an

153 To assess the risk for ICH associated with the use of SSRIs compar

154 variation at the LRRK2 locus contributes to the risk for idiopathic PD.

155 The risk for in-hospital mortality was similar between t

156 ortional hazards regression models estimated the risk for incident fractures based on mental disorder

157 Relatively little is known about the risk for incident liver disease in psoriasis (PsO),

158 and only if the potential benefits outweigh the risks for individual patients and after a discussion

159 g colonized athletes decreased significantly the risk for infection (relative risk reduction = 0.33;

160 ble therapeutic measures aimed at preventing the risk for infection in WHIM patients are discussed.

161 to bind the complement may help to stratify the risk for inferior outcomes associated with dnDSA.

162 Among elderly Medicare enrollees, the risk for interval CRC was higher in black persons th

163 At 8 months, the risk for iron deficiency was reduced in the delayed

164 xaban and dabigatran significantly decreased the risk for ischemic stroke or systemic embolism (p = 0

165 y of thrombocytopenia did not correlate with the risk for IVH, and platelet transfusions did not redu

166 (PIH) but can pose a clinical dilemma given the risk for laser-induced or exacerbated PIH.

167 (PIH) but can pose a clinical dilemma given the risk for laser-induced or exacerbated PIH.

168 disease (CV) and cerebrovascular disease to the risk for late-onset Alzheimer disease (LOAD) has bee

169 g radiotherapy (RT) for childhood cancer and the risk for later cataract.

170 iated with neuropsychological impairment and the risk for later psychiatric disorders.

171 Fetal growth also predicts the risk for later psychopathology.

172 ernal emotional well-being likewise predicts the risk for later psychopathology.

173 here were also no significant differences in the risk for life-threatening/serious systemic hemorrhag

174 t proton pump inhibitors (PPIs) may increase the risk for listeriosis.

175 8-1.11), whereas history of stroke increased the risk for LOAD (OR, 1.96; 95% CI, 1.56-2.46).

176 own that antecedent CV risk factors increase the risk for LOAD, although other investigations have fa

177 demographic and clinical factors predicting the risk for long-term effects of cancer therapy are wel

178 to the STS score significantly reclassified the risk for longer term mortality (integrated discrimin

179 deviation (SD) in BMI (4.65 Kg/m(2)) raised the risk for lung cancer overall (OR = 1.13; P = 0.10).

180 Aspirin increased the risk for major bleeding (RR, 1.54; 95% CI, 1.30-1.82

181 The risk for major depression was approximately three ti

182 luenza A(H1N1) vaccination does not increase the risk for major pregnancy and birth adverse outcomes,

183 The small increase in the risk for malformations observed with risperidone req

184 may be observed with serial imaging because the risk for malignancy is low.

185 LR9 activation via the cag island may modify the risk for malignancy within the context of H. pylori

186 effects shape brain function, behavior, and the risk for mental illness.

187 radiation used in cancer treatment increases the risk for metabolic disease later in life.

188 mTOR complex 1 (mTORC1) signalling increases the risk for metabolic diseases, including type 2 diabet

189 In this study, we evaluated the risk for misclassification when using the IDF single

190 correlated with nodal status after NCT, and the risk for missing nodal metastases without axillary s

191 h OUD, with the further benefit of obviating the risk for misuse and diversion of daily buprenorphine

192 diac resynchronization therapy (CRT) reduces the risk for mortality and heart failure-related events

193 esium was associated with a 49% reduction in the risk for mortality due to liver diseases.

194 The risk for mortality was similarly decreased for any r

195 od pressure of less than 150 mm Hg to reduce the risk for mortality, stroke, and cardiac events.

196 y sex and how these differences compare with the risk for mortality.

197 orn by Caesarean because of FPD is 2.8 times the risk for mothers born vaginally.

198 The risk for MRSA skin and soft tissue infection within

199 hat remains during DNA replication increases the risk for mutagenesis.

200 ses; however, their chronic intake increases the risk for mycobacterial infections.

201 nsplantation is associated with reduction in the risk for myocardial infarction (MI) in patients with

202 Further study is needed to determine whether the risk for myocardial infarction increases with second

203 ions in regulation of these processes impact the risk for NASH and NASH cirrhosis.

204 wer effective dose of bevacizumab may reduce the risk for neurodevelopmental disability or detrimenta

205 rd cytochrome P450 activity, which increases the risk for new compounds to be susceptible to AOX nucl

206 .05 for intermediate vs. high volume) as was the risk for new dialysis post PCI.

207 However, the risk for nonfatal CHD is consistently lower for blac

208 In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relati

209 Parental stress exposures are implicated in the risk for offspring neurodevelopmental and neuropsych

210 rnal inflammation during pregnancy increases the risk for offspring psychiatric disorders and other a

211 D4(+) T-cell depletion is linked directly to the risk for opportunistic infections and infection-asso

212 hat early omega-3 supplementation may reduce the risk for or delay the onset of AD symptoms in APOE4

213 piness scale (ESS) were applied to determine the risk for OSAS.

214 However, the association of aspirin use with the risk for other cancer types and the potential popula

215 These CNVs also increase the risk for other neurodevelopmental disorders, such as

216 of 2.3 (95% CI, 1.8 to 2.9), comparable with the risk for patients with the lowest eGFR/lowest ACR.

217 re 16 weeks' gestation significantly reduces the risk for PE.

218 Maternal obesity increases the risk for pediatric obesity; however, the molecular m

219 ri colonizes the human stomach and increases the risk for peptic ulcer disease and gastric carcinoma.

220 To examine the risk for perinatal complications in women with a his

221 -derived beta3-AR agonists included reducing the risk for phospholipidosis, the risk of formation of

222 The risk for PME is low and the number of patients benef

223 that the MTHFR C677T polymorphism increases the risk for POAG development in Saudi population and ca

224 ecipients will likely increase and with that the risk for post-transplant KS.

225 nticoagulant effects of heparin and to limit the risk for postoperative bleeding.

226 The risk for postoperative LD after resection for HCC in

227 y whether pretransplant malignancy increases the risk for posttransplant malignancy.

228 reduce maternal smoking not only will lower the risk for preterm birth but also will improve late re

229 terine inflammatory condition that increases the risk for preterm birth, death, and disability becaus

230 ) promote more severe wheezing illnesses and the risk for progression to asthma.

231 estimated to confer a 7% to 9% reduction in the risk for prostate cancer death per year of MLT.

232 Maternal inflammation and diabetes increase the risk for psychiatric disorders in offspring.

233 d HRCT findings were investigated to predict the risk for PTB.

234 association between fluoroquinolone use and the risk for RD.

235 es in the experience of morbidity, including the risk for readmission to the hospital after an initia

236 The risk for recurrence in patients with a first unprovo

237 conditions associated with AKI may increase the risk for recurrent AKI.

238 This study evaluated the risk for recurrent myocardial infarction (MI), CHD e

239 od pressure of less than 140 mm Hg to reduce the risk for recurrent stroke.

240 ing the life expectancy of patients; however the risk for relapse remains, due to persistence of leuk

241 upper-respiratory viral infections increase the risk for relapse.

242 the presentation of severe PVS, and examined the risk for restenosis after intervention using either

243 the current use of oral fluoroquinolones and the risk for retinal detachment (RD), but the existence

244 (3) Genetic counseling and testing clarify the risk for retinoblastoma in children with a family hi

245 oss creatinine and urine output domains with the risk for RRT and likelihood of renal recovery and su

246 Mupirocin was observed to reduce the risk for S. aureus infections by 59% (cpRR, 0.41; 95

247 A model developed to calculate the risk for SCD in trials with systematic collection of

248 ry of infections have independent effects on the risk for schizophrenia, and the common genetic risk

249 number variants contribute significantly to the risk for schizophrenia, with the 22q11.2 locus consi

250 am reveal mechanisms explaining efficacy and the risk for secondary autoimmunity with treatment of MS

251 re compartment and thereby likely increasing the risk for seeding of autoimmune B cell responses.

252 lence, and stimulation-induced patterns, and the risk for seizures.

253 To compare the risk for selected birth outcomes by maternal ART reg

254 y limiting collateral damage to the host and the risk for sepsis.

255 isions about treatment should be informed by the risk for serious adverse health effects and the symp

256 uterine cancer after RRSO was not increased, the risk for serous/serous-like endometrial carcinoma wa

257 unities in infants during childhood increase the risk for several diseases, highlighting the importan

258 at having a slightly older sibling increases the risk for severe neonatal HPeV infections.

259 The risk for skin cancer has been well characterized in

260 be considered in OTRs who develop cancer if the risk for skin cancer is of concern.

261 s a modifiable behavior that can help reduce the risk for skin cancer, prevent sunburns, mitigate pho

262 The risks for SMN and death due to SMN were increased af

263 e newly identified variants likely influence the risk for smoking-related diseases such as lung cance

264 uld be transfused prophylactically to reduce the risk for spontaneous bleeding in hospitalized adult

265 nin reuptake inhibitors (SSRIs) may increase the risk for spontaneous intracranial hemorrhage (ICH),

266 The risk for sporadic AD may consequently depend on incr

267 The risk for stroke after transcatheter aortic valve rep

268 od pressure of less than 140 mm Hg to reduce the risk for stroke or cardiac events.

269 and is associated with a 5-fold increase in the risk for stroke.

270 on rate, identify risk factors, and estimate the risk for subsequent infection, associated with the c

271 zation in asymptomatic athletes and estimate the risk for subsequent MRSA infection.

272 The risk for such in-breast events persists over time, t

273 In the current therapeutic era, the risk for sudden cardiac death (SCD) after non-ST-seg

274 However, the recognition of the risk for sudden cardiac death among basketball playe

275 Objective: To describe the risk for suicide during the 90 days after hospital d

276 ) locus genetic variants are associated with the risk for systemic lupus erythematosus (SLE); however

277 llectual disability-associated CNVs increase the risk for SZ but have not yet been implicated in SZ b

278 regard to the secondary efficacy end point, the risk for the composite of major adverse cardiovascul

279 esence of nonobstructive LM plaque increased the risk for the composite outcome in women (adjusted ha

280 Chronic intestinal inflammation increases the risk for the development of CRC.

281 intake can lead to obesity, which increases the risk for the development of diabetes and cancer.

282 e of the APOE gene, apoE4 strongly increases the risk for the development of late-onset Alzheimer's d

283 the increased risk was relatively lower than the risk for the lowest GS quintile and obesity class II

284 -C of less than 70 mg/dL, evolocumab reduced the risk for the primary endpoint (hazard ratio [HR], 0.

285 Existing SAVR risk models accurately predict the risks for the population undergoing SAVR, but compar

286 The aim of this study was to compare the risk for thromboembolic events, bleeding, and mortal

287 likely to produce sustained benefits without the risk for tolerance or adverse effects associated wit

288 isability (MMD) (that is, MMD burden) and on the risk for transitions into and out of MMD.

289 The risks for transplant outcomes associated with baseli

290 nical concern and has been shown to increase the risk for treatment failure.

291 oss unconnected systems of care may increase the risk for unsafe prescribing, particularly in persons

292 Objective: To determine the risk for uterine cancer and distribution of specific

293 ciation between oral fluoroquinolone use and the risk for uveitis-associated systemic illnesses, whic

294 loxacin or ciprofloxacin appears to increase the risk for uveitis.

295 anges in sRBC biomechanics, thereby reducing the risk for vaso-occlusion in our models.

296 The risk for venous thromboembolism (VTE) is increased i

297 investigate the relationship between RWT and the risk for ventricular tachyarrhythmia (VA) in patient

298 gic treatment with bisphosphonates to reduce the risk for vertebral fracture in men who have clinical

299 The risk for violent reinjury among high-risk, assault-i

300 Background: Because of the risk for Zika virus infection in the Americas and th