ライフサイエンスコーパス: the risk of

1 the number of normal stem cell divisions and the risk of 17 cancer types in 69 countries throughout t

2 The risk of 3-month mortality was similar between patien

3 ox proportional hazards regression models on the risk of a disease milestone and death were used.

4 1 year of trastuzumab significantly reduced the risk of a disease-free survival event (HR 0.76, 95%

5 We observed a similar 59% decline in the risk of a district reaching the epidemic threshold.

6 ger than 15 years and DMD exposure decreased the risk of a first Expanded Disability Status Scale (ED

7 95% CI, 3.63-25.92) significantly increased the risk of a large metachronous SP.

8 a surgeon were significantly associated with the risk of a patient having any complication (odds rati

9 utero exposure to cigarette smoke increases the risk of AA and bronchopulmonary dysplasia (BPD) in c

10 Here, we explore the risk of accidental spread posed by self-propagating

11 The risk of acute graft-versus-host disease (GVHD) is hi

12 compared with femoral access (FA), mitigates the risk of acute kidney injury (AKI).

13 ine-based contrast material is minimized and the risk of acute nephropathy is reduced.

14 e use of cytolytic induction therapy reduced the risk of acute rejection by 32% (OR 0.68, 0.62-0.75),

15 Longstanding diabetes might increase the risk of acute rejections.

16 hether DNA methylation alterations influence the risk of AD-ND codependence or the other way around.

17 s important clinical implications because of the risk of additional tumors and the possibility of fam

18 supplementation leads to a large increase in the risk of advanced AMD in some genotype subgroups.

19 We aimed to prospectively assess the risk of advanced fibrosis in first-degree relatives

20 s no significant between-group difference in the risk of adverse events, which were reported in 68.7%

21 ggested that systemic inflammation increases the risk of age-related macular degeneration (AMD).

22 Two questions that presented the risk of AK as not progressing to cancer had the lowe

23 cin and piperacillin/tazobactam may increase the risk of AKI in hospitalized children.

24 The risk of all second cancers was 1.3-fold higher for H

25 In the first decade after donation, the risk of all-cause mortality and cardiovascular event

26 4), and fish (RR: 0.93; 95% CI: 0.88, 0.98), the risk of all-cause mortality decreased; higher intake

27 odel to examine the relation of knee SxOA to the risk of all-cause mortality.

28 biotics during the first 2 years of life and the risk of allergies/atopies including hay fever, eczem

29 The risk of allograft loss increased in patients with a

30 of immunosuppression and thus help determine the risk of alloimmune response.

31 We aimed to determine the risk of alopecia areata (AA) and vitiligo associated

32 led trials) showed that cell therapy reduced the risk of amputation by 37%, improved amputation-free

33 We determined the risk of an alcohol abuse diagnosis on incident AF, M

34 The risk of anal cancer due to high-risk human papilloma

35 The risk of any AD and several individual ADs was consis

36 ovariate) was associated with an increase in the risk of any coronary event (2091 events; hazard rati

37 sses and aeroallergen sensitization increase the risk of asthma at school age.

38 advantage at the cost of modestly promoting the risk of autoimmunity.

39 of the enhanced host catabolic activity with the risk of being eliminated by the cell's cytosolic imm

40 Studies (QUADAS-2) tool was used to evaluate the risk of bias and applicability of individual studies

41 The risk of bias and variability between studies was ass

42 ssessed using the Newcastle-Ottawa Scale and the Risk of Bias in Non-randomized Studies of Interventi

43 The risk of bias of included studies was assessed using

44 The risk of bias was low for 3 included RCTs.

45 Understanding the risk of birth defects associated with Zika virus inf

46 ed the associations of mobile phone use with the risks of brain, acoustic neuroma, and parotid gland

47 ethylation was significantly associated with the risk of breast and gynecological cancers, and it may

48 large prospective cohort study, we evaluated the risk of breast cancer in relation to indoor heating

49 r discontinuation of hormonal contraception, the risk of breast cancer was still higher among the wom

50 ain polyunsaturated fatty acid, might reduce the risk of bronchopulmonary dysplasia, but appropriatel

51 ations in the BRCA1 and BRCA2 genes increase the risk of cancer.

52 changes in lipid and lipoprotein levels, and the risk of cardiovascular events involving 102837 parti

53 The efficacy of NHE inhibitors on the risk of cardiovascular events may be enhanced when h

54 deciliter (0.78 mmol per liter) and reduced the risk of cardiovascular events.

55 The present study aimed to determine the risk of cataractogenesis associated with radiation e

56 The time to hemodynamic stabilization, the risk of catecholamine therapy and the duration of su

57 further threatens oxygen delivery increasing the risk of cerebral infarction.

58 The risk of cerebrovascular complications is less well u

59 exposure, especially to cat, for attenuating the risk of childhood asthma, pneumonia, and bronchiolit

60 d that prenatal maternal stress may increase the risk of childhood externalizing disorders, yet no la

61 cals confers benefits for health by reducing the risk of chronic diseases via regulation of oxidative

62 m (Cd) and mercury (Hg) is known to increase the risk of chronic diseases.

63 centration should be considered in assessing the risk of citrate accumulation.

64 Obesity increases the risk of clinical decompensation in cirrhosis, possib

65 sis showed that echinocandin therapy altered the risk of clinical failure.

66 ophylactic CNS-directed therapies may reduce the risk of CNS involvement; however, no consensus exist

67 with oral corticosteroids may help to reduce the risk of CNVM development, and anti-VEGF therapy for

68 d CoB-resistant T cell populations to reduce the risk of CoBRR.

69 ocializing and social participation buffered the risk of cognitive decline resulting from housing dam

70 INTERPRETATION: We found the risk of colorectal cancer in Asian patients with ulc

71 ompt treatment is very important to decrease the risk of complications, and thus, to improve the prog

72 The risk of conversion from a clinically isolated syndro

73 ial to determine whether minocycline reduces the risk of conversion from a first demyelinating event

74 he blood eosinophil count is associated with the risk of COPD exacerbations, mortality, decline in FE

75 9 for highest vs. lowest quintile) increased the risk of COPD.

76 or (TFPI) regulating protein] gene increases the risk of coronary artery disease, the leading cause o

77 with LDL-C >/=190 mg/dL, pravastatin reduced the risk of coronary heart disease by 27% (P=0.033) and

78 (P=0.037) during the initial trial phase and the risk of coronary heart disease death, cardiovascular

79 he associations between 1) lipid species and the risk of CVD (myocardial infarction, stroke, or cardi

80 ther caffeinated or decaffeinated, may lower the risk of CVD and IHD mortality in patients with a pri

81 r, many believers still want to fast even at the risk of damaging their health.

82 th facilities resulted in a 25% reduction in the risk of death (HRR = 0.73, 95% CI:0.58 to 0.91) and

83 7-, and 8.80-fold increase, respectively, in the risk of death and myocardial infarction.

84 ear after discharge was markedly higher than the risk of death beyond the first year of discharge.

85 vors; 9/28 who died) significantly increased the risk of death compared to those with no increase or

86 icant and clinically meaningful reduction in the risk of death compared with bortezomib.

87 and ozone were associated with increases in the risk of death of 13.6% (95% CI, 13.1 to 14.1) and 1.

88 itiated at 6 to 24 hours after birth reduces the risk of death or disability at 18 months among infan

89 After adjustment, age did not increase the risk of death up to 80 years.

90 The risk of death was 3.1x more likely among patients wh

91 We estimated the risk of death-censored graft loss and mortality afte

92 contribution of each level of adjustment to the risk of death.

93 sed a matched case-cohort design to estimate the risk of deaths by suicide and attempted suicide in i

94 atients with cirrhosis, statin use decreased the risk of decompensation, mortality, and HCC in a dose

95 as associated with a significant decrease in the risk of delirium (odds ratio, 0.47; 95% CI, 0.38-0.5

96 amine the association between statin use and the risk of delirium in hospitalized patients with an ad

97 The risk of developing AF was 21.99 times higher (95% co

98 Whether a reported decline in the risk of developing age-related macular degeneration

99 one deacetylase 4 (HDAC4) is associated with the risk of developing an ED in humans.

100 (HRs) and 95% confidence intervals (CIs) for the risk of developing breast cancer using Cox proportio

101 ortional hazards models were used to compare the risk of developing CKD in HCV patients compared with

102 nsive awareness of the factors that increase the risk of developing CNS cancers in affected individua

103 We aimed to assess the risk of developing diabetes mellitus and its effects

104 opeptide therapy does not appear to increase the risk of developing diabetes mellitus in NET patients

105 associations of ASB and SSB consumption with the risk of developing DM and the potential benefit of r

106 ng pathophysiological mechanisms may explain the risk of developing epilepsy following incident depre

107 The risk of developing glaucoma increases with age; ther

108 Specifically, the risk of developing heart failure is higher in patien

109 dify the clinical course of AMD and increase the risk of developing specific sub-phenotypes.

110 The risk of developing weak grip strength (assessed as a

111 There was no significant difference in the risk of DFS events (hazard ratio [HR], 1.00; 95% CI,

112 Strategies aim to reduce the risk of DGF could potentially improve graft survival

113 , but less is known about their influence on the risk of diabetes.We examined the associations betwee

114 pe 2 diabetes (P=6.1x10(-4)) associated with the risk of diabetic kidney disease.

115 oding alleles of lower frequency influencing the risk of diabetic kidney disease.

116 response associations between LTPA, BMI, and the risk of different HF subtypes.

117 the viral genome, for the telomere, and for the risk of disease associated with carrier status is ha

118 adjuvant and adjuvant immunotherapies reduce the risk of disease relapse after resection of murine PD

119 Evidence-based estimates of the risks of disease-related outcomes comparing IPNI and

120 ed barriers to diabetes care may help reduce the risk of DR.

121 bidity does not seem to significantly affect the risk of dying from PCa.

122 after the first separation attempt increases the risk of dying.

123 urgery months 13-24 as the reference period, the risk of ED visit or hospitalization in the 0- to 12-

124 The risk of emerging pandemic influenza A viruses (IAVs)

125 ltivariable prediction models for estimating the risk of EOS among late preterm and term infants base

126 To determine the effect of depression on the risk of epilepsy and seizure outcomes.

127 etween nut and peanut butter consumption and the risk of esophageal and gastric cancers and their dif

128 southern Beaufort Sea (SB), which may alter the risks of exposure to pathogens and contaminants.

129 an be resource demanding, thereby increasing the risk of failure of the overall antibody discovery pr

130 significantly more disability and 1.8 times the risk of falls compared with CIPN- ( P < .0001).

131 tly increase the confidence in calls, reduce the risk of false positives, and help characterize compl

132 ovide appropriate and renewed assessments of the risks of feeding modes for the future development of

133 ds ratios (aORs) of the exposure to PM10 and the risks of fetal cardiovascular malformations.

134 A number of factors can increase the risk of FGR, one of which is poor maternal diet.

135 However, the risk of FTR associated with increasing complications

136 g liver health may be important for reducing the risk of future CHF events, particularly among HIV an

137 investigate whether HIV infection increases the risk of future HFrEF and HFpEF and to assess if this

138 oderate the effect of adverse life events on the risk of GAD.

139 lowest intakes of nuts or peanut butter and the risk of gastric cardia adenocarcinoma, esophageal ad

140 r consumption were inversely associated with the risk of gastric noncardia adenocarcinoma.

141 whether the protective effect of statins on the risk of glaucoma varies depending on the daily dosag

142 tive genetic risk score analyses showed that the risk of gout increased for individuals with the grow

143 The risk of graft failure in young kidney transplant rec

144 odds ratios and 95% confidence intervals for the risk of GWs according to HPV-6 variants were calcula

145 associated with a considerable reduction in the risk of HCC.

146 avidity index and DNAemia may help to assess the risk of HCMV fetal transmission.

147 ex (CHVI) based on factors known to increase the risks of health effects from air pollution and wildf

148 al cadmium in adolescents may play a role in the risk of hearing loss.

149 Little is known whether PH heightens the risk of heart failure (HF) admission or mortality am

150 Statin use also decreases the risk of hepatocellular carcinoma (HCC) in patients w

151 gical stress is commonly thought to increase the risk of herpes zoster by causing immunosuppression.

152 Although the risk of HF remained elevated among those with cAVB i

153 cardiac radiation exposure and may increase the risk of HF.

154 ound evidence that HSV-2 infection increases the risk of HIV acquisition, but these reviews are now m

155 However, the risk of hospitalization (adjusted hazard ratio, 1.34

156 ssion, anxiety, and AD in adults and examine the risk of hospitalization and suicide.

157 rpose The aim of this study was to determine the risk of human papillomavirus (HPV)-related carcinoma

158 either indoor activity or sleeping time with the risk of hyperglycemia among offspring born to GDM mo

159 an improve glucose control while alleviating the risk of hypoglycaemia in adults with HbA1c below 7.5

160 f egg protein from age 4 to 6 months reduces the risk of IgE-mediated egg allergy in infants with her

161 elian randomization suggest that ALT reduces the risk of IHD, probably through reducing triglyceride

162 The risk of incident ASCVD may be estimated in patients

163 Here we aimed to establish the risk of incident cardiometabolic multimorbidity (ie,

164 h diabetes prevalence and HBV infection with the risk of incident diabetes.

165 6-80, smoking was positively associated with the risk of incident respiratory diseases, hypertension

166 Vitamin A deficiency strongly predicted the risk of incident tuberculosis disease among HHCs of

167 -GS and should be further explored to reduce the risk of infection.

168 uggest that novel oral anticoagulants reduce the risk of intraocular bleeding by approximately one-fi

169 To characterize the risk of intraocular bleeding with novel oral anticoa

170 It is unclear if the risk of intraocular bleeding with novel oral anticoa

171 SECM investigations to ionic processes, but the risk of irreversible Hg amalgam saturation limits th

172 evidence of a developmental contribution to the risk of later allergic disorders and suggest that in

173 t recommended would lead to more lowering of the risk of left ventricular hypertrophy (LVH) in patien

174 that natural killer (NK) cells can decrease the risk of leukemia relapse, we initiated a phase 1 dos

175 ry spares surrounding normal liver, reducing the risk of liver failure.

176 Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring

177 The risk of long-term overall stroke was significantly h

178 ctive strategy that must be balanced against the risk of loss to follow-up, particularly among patien

179 aternal age at birth independently increases the risk of low birth weight (<2,500 g) and preterm birt

180 , .15-.84), with nonsignificant decreases in the risk of low birth weight (0.68; .29-1.57) and fetal

181 ect of malaria infection during pregnancy on the risk of low birthweight (LBW; <2,500 g) may depend u

182 iple micronutrient supplementation decreases the risk of low birthweight and potentially improves oth

183 rnal tobacco smoking independently increased the risk of LRTI 1.76-fold (95% CI: 1.24-2.51) after adj

184 e to antimicrobial and steroid therapies and the risk of lung infection.

185 ients with hypertension and whether reducing the risk of LVH explains the reported cardiovascular dis

186 The risk of MACCE with CABG or PCI was compared using mu

187 otent P2Y12 inhibitors significantly reduced the risk of MACE by 14% in women (hazard ratio [HR]: 0.8

188 d glucose tolerance, acarbose did not reduce the risk of major adverse cardiovascular events, but did

189 inhibitors to fibrinolytic therapy increased the risk of major bleeding by 1.27-8.82-times compared w

190 The risk of meningioma was assessed by using data from t

191 population could prove useful in determining the risk of metastatic disease, and its manipulation mig

192 ared with less intensive glucose control, on the risk of microvascular events.

193 The risks of MiP and malaria-attributable low birthweigh

194 e exposed to higher MF levels had 2.72 times the risk of miscarriage (hazard ratio = 2.72, 95% CI: 1.

195 rom individual appointments and investigated the risk of missing a general practice appointment using

196 SBP was continuously related to the risk of mitral regurgitation with no evidence of a n

197 linear association between PCSK9 levels and the risk of mortality (hazard ratio [HR]: 1.24; 95% conf

198 a later-generation fluoroquinolone had half the risk of mortality compared with participants either

199 rkplace interventions on arsenic exposure on the risk of mortality from all causes, heart disease, an

200 The risk of mortality of RPM+ patients was similar to st

201 er hemolysis nor thrombotic events increased the risk of mortality.

202 anced physiological and cognitive ageing and the risk of mortality.

203 t the effect of ADHD medication treatment on the risk of MVCs remains unclear.

204 , and Scopus) and sought unpublished data on the risk of NDI after invasive GBS disease in infants <9

205 dance of bovine-origin products might reduce the risk of necrotising enterocolitis, but the absolute

206 consensus guidelines effectively stratified the risk of neoplasia and malignancy.

207 enetically influenced regulation in brain on the risks of nicotine dependence, heavy smoking and cons

208 d a positive association of TV watching with the risk of obesity, and an inverse association of eithe

209 DH before and after the development of POAG, the risk of ODH for POAG, and risk factors for ODH were

210 nd was associated with a >2-fold increase in the risk of offspring obesity at ages 6-11 y (adjusted R

211 than qSOFA and CRB, significantly increasing the risk of over-treatment and being comparable with the

212 ts, especially yogurt and cheese, may reduce the risk of overall and CVD mortality.

213 The risk of overall impaired vision increased by 1.20 ti

214 of these overdiagnosed cancers, may increase the risk of patient harms.

215 OUND & AIMS: A system is needed to determine the risk of patients with Barrett's esophagus for progre

216 nts without PBC is increased irrespective of the risk of PBC development.

217 e agency's failure to adequately account for the risks of perchlorate-a well-characterized endocrine-

218 Clinicians should consider the risk of perforation and counsel patients/families ac

219 obesity with other risk factors may increase the risk of periodontitis.

220 ined with diet-induced overweight/obesity on the risk of periodontitis.

221 However, the risk of PET false-negative results in the presence o

222 nvironmental interventions that might offset the risk of post-traumatic stress disorder after cardiov

223 To investigate the risk of posterior capsular rupture (PCR) during cata

224 Resective neurosurgery carries the risk of postoperative cognitive deterioration.

225 s of nepafenac 0.3% over vehicle in reducing the risk of postoperative ME, with the integrated analys

226 , compared with standard management, reduced the risk of postoperative organ dysfunction.

227 Our objective was to assess the risk of posttransplant cancer in this patient group.

228 stic regression models were used to estimate the risk of pre-treatment (pre-ART) loss from care and e

229 No difference between the groups in the risk of prednisolone use for exacerbation was found

230 Maternal asthma increased the risk of preeclampsia.

231 groups can lead to a considerable change in the risk of premature death.

232 contribute to the duration of gestation and the risk of preterm birth, robust associations with gene

233 Based on multivariable analysis, the risk of primary nonadherence was 16 percentage point

234 ers with respect to the stage of disease and the risk of progression.

235 The risk of psoriasis development was found to be high a

236 s found between domestic or commuting PA and the risk of PTB.

237 nostic criteria based on the results to rank the risk of PTB.

238 nd diagnostic radiation treatments to reduce the risk of radiation-related adverse systemic effects.

239 d once 25% or more of the retina is involved the risk of RD and visual loss increases significantly.

240 used to undertake a pragmatic comparison of the risk of re-presentation to hospital with vivax malar

241 The risk of re-presentation with vivax malaria within 1

242 ir tamponade duration beyond 2 hours reduced the risk of rebubbling (HR 0.36 [95% CI 0.18-0.71, P = .

243 For 96 eyes with recurrent pterygium, the risk of recurrence 6 months after CAG was reduced by

244 Although the risk of recurrence beyond MC decreased over time, it

245 The risk of recurrent ischemic and bleeding events after

246 supplements have not been shown to decrease the risk of relapse in patients with Crohn's disease.

247 isms by which stressful life events increase the risk of relapse in recovering cocaine addicts are no

248 The risk of reoperation was significantly increased in p

249 INTERPRETATION: The risk of residual or recurrent CIN2+ is significantly

250 CHOP ROP model was applied weekly to predict the risk of ROP.

251 We aimed to assess the risk of Sabin 2 transmission after a polio vaccinati

252 The risk of SAP increased in a dose-response manner with

253 The risk of SCC after organ transplantation has declined

254 ck accurate tool to aid clinical judgment of the risk of seizures in critically ill patients.

255 n 67.2% of those in the placebo group, or in the risk of serious adverse events (in 8.3% in the vacci

256 The risk of serious complications was higher in the elde

257 The risk of serious infection should not be a key discri

258 We assessed the risk of serious infections for biologics used to tre

259 INTERPRETATION: Immediate ART reduces the risk of several severe bacterial infections in HIV-p

260 This variant reduces the risk of severe malaria by 40% and has recently incre

261 rology is superior to CRD alone in assessing the risk of severe reactions to hazelnut, particular in

262 immunodeficiency virus (HIV) RNA levels and the risk of sexual HIV transmission.

263 gression analysis was performed to calculate the risks of SHMs that occurred after WDTC treatment and

264 To study temporal trends for the risk of skin cancer, particularly SCC, after organ t

265 The risk of sporadic colorectal cancer in Asian populati

266 Knowledge of factors affecting the risk of spread are key components for surveillance p

267 on ZA every 3 months was more CE in reducing the risks of SRE than monthly denosumab.

268 The risk of SSTI and respiratory infection decreased aft

269 irth weight remains strongly associated with the risk of stillbirth and infant death and neonatal mor

270 t supplements did not significantly increase the risk of stillbirth or neonatal, 6-month, or infant m

271 The risk of subdural hematoma was highest when a VKA was

272 with a PFO who had had a cryptogenic stroke, the risk of subsequent ischemic stroke was lower among t

273 mania, disrupting normal life and increasing the risk of suicide greatly.

274 m the Swedish national registers to estimate the risk of suicide in OCD and identify the risk and pro

275 ity or substance use disorder also increased the risk of suicide.

276 After demographic adjustment, the risk of surgical delay was significantly increased i

277 brain injury (TBI), but it is possible that the risk of TBI is greater in the prodromal period of PD

278 t connections to the hippocampus, we control the risk of temporal lobe seizures during a specific tim

279 nsider dietary supplements that might reduce the risk of the disease progressing from the intermediat

280 , evolocumab treatment significantly reduced the risk of the primary end point (1344 patients [9.8%]

281 clonal haemopoiesis significantly increased the risk of therapy-related myeloid neoplasm development

282 To investigate the risk of these impacts, we investigated the effect of

283 hancing mechanical properties while reducing the risk of thrombogenesis.

284 y thrombin-dependent feedback loops enhances the risk of thrombosis.

285 Of importance, the risk of TLF and TLR for patients with BVS was higher

286 slate into clinical improvement and outweigh the risk of transfusion.

287 mutations in the Gag P2/NC CS could increase the risk of treatment failure if there is increased use

288 and adaptive immunity can effectively reduce the risk of tumor recurrence after surgery, facilitating

289 ncreasing body mass index (P=2.2x10(-5)) and the risk of type 2 diabetes (P=6.1x10(-4)) associated wi

290 The risk of type 2 diabetes was significantly greater du

291 uency missense variant in ADCY7 that doubles the risk of ulcerative colitis.

292 t to simplify diagnosis could be overcome by the risk of undiagnosed HBP.

293 imprecise, there was no alarming increase in the risk of upper gastrointestinal bleeding; the effect

294 We performed a meta-analysis to evaluate the risk of venous thromboembolism (VTE) in pregnant wom

295 quired for proteinase inactivation, increase the risk of venous thrombosis.

296 reased by 1.20 times (95% CI, 1.01-1.43) and the risk of visual impairment/severe visual impairment/b

297 k skin and low exposure to sunlight increase the risk of vitamin D insufficiency in children.The aim

298 The risk of VL relapse in coinfected patients was high,

299 therapy showed a nonsignificant reduction in the risk of waitlist dropout due to progression (relativ

300 nd a period of weight stabilization (WS) and the risk of weight regain.In this randomized controlled