1 This was achieved by strategically expanding 
the scope of a building block-based synthesis platform t
 
     2     The study provides valuable insight into 
the scope of a rare hetero-Pauson-Khand reaction, a powe
 
     3  OMOs and could feasibly be completed within 
the scope of a single PhD thesis.                       
 
     4 not only improves accuracy but also broadens 
the scope of absolute cell fraction predictions from tum
 
     5  has contributed to significant expansion of 
the scope of accessible aerobic oxidation reactions.    
 
     6                This strategy greatly expands 
the scope of accessible DNA nanostructures and would fac
 
     7 ng of Salmonella were performed according to 
the scope of accreditation of the respective laboratorie
 
     8 ated hypervalent iodine reagents will expand 
the scope of aerobic oxidation chemistry in chemical syn
 
     9  We conclude that NMHS significantly extends 
the scope of analyses of multidimensional, nonlinear net
 
    10                  We have, therefore, widened 
the scope of analysis to include in vitro-induced T-cell
 
    11                                   We discuss 
the scope of applicability of most commonly used measure
 
    12 c liquids, helping the reader to distinguish 
the scope of application of different methods of calcula
 
    13           SNAPCAR-produced ssDNA will expand 
the scope of applications in nanotechnology, gene editin
 
    14 c authentication, thus potentially expanding 
the scope of applications in self-powered wearable medic
 
    15 nical connections between metabolites limits 
the scope of applications of such tools.                
 
    16                                              The scope of aryl halides and thiol partners includes ov
 
    17                                           As 
the scope of assays used in molecular genetics has expan
 
    18 ading to these types of materials as well as 
the scope of available characterization techniques will 
 
    19                                              The scope of available MRI contrast agents has expanded 
 
    20 g unsupervised clustering approaches outside 
the scope of bio-medical research, with the additional a
 
    21           Geometric isomerization can expand 
the scope of biological activities of natural products. 
 
    22                          Avoiding HF extends 
the scope of Boc SPPS to post-translational modification
 
    23 for manipulating boron in cells could expand 
the scope of boron chemistry in living systems.         
 
    24                                              The scope of both the amine nucleophiles and homoallylic
 
    25  controlled modification of graphene extends 
the scope of candidate species that would not otherwise 
 
    26 ment guidelines have significantly broadened 
the scope of candidates eligible for statin therapy.    
 
    27 ehydes and imines have dramatically expanded 
the scope of carbonyl and iminyl chemistry by facilitati
 
    28  broadly applicable strategy that can expand 
the scope of catalyst-controlled stereoselective olefin 
 
    29                        Some raised issues of 
the scope of CGS explanations versus competing ones.    
 
    30 ic acids and other polymers that lie outside 
the scope of ChEBI.                                     
 
    31 tor' nanostructures, holds promise to expand 
the scope of chemical reactions possible with plasmonic 
 
    32                                              The scope of correlation analysis was extended beyond Mn
 
    33      As part of our ongoing effort to expand 
the scope of cross-coupling reactions of alkyl electroph
 
    34 similar, unactivated C-H positions is beyond 
the scope of current chemocatalytic methods.            
 
    35 logenetic network inference lags well behind 
the scope of current phylogenomic studies.              
 
    36                        This paper summarizes 
the scope of CVD nonadherence, describes key U.S. Food a
 
    37 s to enhance access to these data, to extend 
the scope of data content and visualizations, and to pro
 
    38 footprinting approach and call into question 
the scope of detectable protein occupancy, especially fo
 
    39 l prove tremendously beneficial in expanding 
the scope of DNA-based nano- and biotechnologies.       
 
    40                        These studies enhance 
the scope of electrophiles for nitroarene arylations and
 
    41 bond formation, thus significantly expanding 
the scope of enantioselective C-H activation reactions. 
 
    42 ing intermediate switch molecules may expand 
the scope of engineered T-cell therapy to solid tumors, 
 
    43                                    We extend 
the scope of European palaeogenomics by sequencing the g
 
    44                 Collectively LOTUS-V extends 
the scope of excitable cell control and simultaneous vol
 
    45 od webs in fragmented landscapes, broadening 
the scope of existing metacommunity theory.             
 
    46                                   To broaden 
the scope of existing methods based on (19)F nucleotide 
 
    47 o-extensometer (ACME), which greatly expands 
the scope of existing methods for measuring mechanical p
 
    48         To facilitate these transformations, 
the scope of existing nanocrystal cation-exchange reacti
 
    49                Future studies should broaden 
the scope of focal consumers, particularly in understudi
 
    50 he phenomena under scrutiny should be within 
the scope of formal methods.                            
 
    51                                              The scope of functionalities and applications of protein
 
    52 c properties were estimated and discussed in 
the scope of GAA self-aggregation in aqueous solutions u
 
    53            Health estimates that fall within 
the scope of GATHER include all quantitative population-
 
    54                                           As 
the scope of general surgery practice continues to evolv
 
    55                                              The scope of general surgery practice has evolved tremen
 
    56  maternal vaccination, are needed to enhance 
the scope of global prevention of GBS disease.          
 
    57 ns are carried out for 13 reactions, to test 
the scope of heavy-atom tunneling in organic chemistry, 
 
    58                           This study expands 
the scope of heterodyned 2D IR spectroscopy to tissues. 
 
    59                         These results expand 
the scope of heterogeneous-backbone foldamer design to a
 
    60 ogenicity are often associated with HGT, but 
the scope of HGT extends far beyond disease-causing orga
 
    61                                        Hence 
the scope of high-precision analytics can be extended to
 
    62                         Further, we extended 
the scope of hippocampal phase precession to include obj
 
    63  Thompson considered genetics to lie outside 
the scope of his work, even though genetics was a growin
 
    64                                              The scope of horizontal heat impacts (Sh) changed on a d
 
    65 e are widespread implications for increasing 
the scope of human genetic variation that can be detecte
 
    66 ver, competing methods tend to be limited in 
the scope of hydrosilane that can be used, which restric
 
    67                             In this context, 
the scope of implementing genomics selection for disease
 
    68 e performed on exome data, which will expand 
the scope of inferences that can be made from existing m
 
    69 ed intercalation compounds, but also extends 
the scope of investigation on high-capacity electrodes.T
 
    70 s subjected to the preparative process, with 
the scope of isolating two low-amount constituents (name
 
    71 A products in an isothermal reaction extends 
the scope of isothermal amplification to enable more use
 
    72 tabases, making it suitable for tasks beyond 
the scope of its original design.                       
 
    73 zes its response properties, and establishes 
the scope of its reactivity.                            
 
    74                This approach greatly expands 
the scope of KATs, KAT complexes, and CoA-dependent enzy
 
    75 uitment to secondary lymphoid tissues expand 
the scope of known adjuvant effects of PorB on the immun
 
    76 is acids is receiving significant attention, 
the scope of known reactions that directly exploit the p
 
    77                                              The scope of lipids as taxonomic markers in microbial ec
 
    78  breast cancer patients is increasing beyond 
the scope of locally advanced disease.                  
 
    79 y control gene knockout and greatly broadens 
the scope of loss-of-function studies in zebrafish.     
 
    80 tion of inorganic complexes further enhances 
the scope of low-voltage ionization.                    
 
    81                                     However, 
the scope of metacognition impairment among drug users i
 
    82 rk presents a tunable workflow for expanding 
the scope of MFA to the genome-scale without trade-offs 
 
    83  selected interventions in LiST to encompass 
the scope of midwifery practice, including prepregnancy,
 
    84           In this work, we report a study on 
the scope of missing values and a robust method of filli
 
    85                            Our results widen 
the scope of Mobius aromaticity dramatically and open pr
 
    86                           This study expands 
the scope of MOF materials with ultrahigh working capaci
 
    87                        Our work has expanded 
the scope of MOF-catalyzed asymmetric reactions and show
 
    88 rect human brain recordings have transformed 
the scope of neuroscience in the past decade.           
 
    89 rative catalytic system dramatically expands 
the scope of NHC organocatalysis by opening up new metal
 
    90 ikely to have a notable effect on broadening 
the scope of olefin metathesis, as the stability of meth
 
    91                           This paper updates 
the scope of Optical Coherence Tomography (OCT) for ENM/
 
    92 hree complementary research disciplines: (1) 
the scope of organic reactions that can be successfully 
 
    93 hereby generating a reduced dataset to limit 
the scope of orthology search for each gene of interest.
 
    94                                              The scope of our approach includes possibilities for sol
 
    95 products and pathways would have been beyond 
the scope of our initial brief report [3].              
 
    96                                              The scope of our method is further highlighted through t
 
    97 ic seizures because these topics were beyond 
the scope of our objective.                             
 
    98                This software package extends 
the scope of our original CIMS package.                 
 
    99                                   We limited 
the scope of our review to large RCTs of supplementation
 
   100                                              The scope of our study was to predict this phenomenon.  
 
   101 s relevant laws and regulations and explores 
the scope of participants' legal duties and the resultin
 
   102  the early experiences of the consortium and 
the scope of participating BEST programs.               
 
   103                         Our findings broaden 
the scope of phenotypes caused by mutations in NFKB1 and
 
   104                   We empirically established 
the scope of physical parameters that govern the metabol
 
   105                                        Given 
the scope of physiological disruption, we conclude that 
 
   106                 The investigation highlights 
the scope of plasmon-mediated light emission as a unique
 
   107 tially seen as a detriment, has now expanded 
the scope of plasmonic applications to exploit the gener
 
   108                             To better define 
the scope of plausible models of archaic admixture betwe
 
   109 metadata, Perturb-seq dramatically increases 
the scope of pooled genomic assays.                     
 
   110 ency, yet their very number vastly increases 
the scope of possible GEI, making it difficult to identi
 
   111 r, are based on optical techniques, limiting 
the scope of potential applications of such powerful scr
 
   112 ns with primary amines, thereby constraining 
the scope of potential biomimetic synthetic applications
 
   113 his approach of "template catalysis" expands 
the scope of potential donors for conjugate addition rea
 
   114                       We have now determined 
the scope of potential interactions between the various 
 
   115 esidual fluid sources and endpoints to bound 
the scope of potential waste stream impacts and (b) desc
 
   116                        Little is known about 
the scope of practice and outcomes in pediatric surgery 
 
   117                                              The Scope of Practice for Primary Care score (scope scor
 
   118                                 Narrowing of 
the scope of practice of US family physicians has been w
 
   119 -hospital emergency medicine are re-defining 
the scope of pre-hospital care.                         
 
   120 ies, computational methods that reach beyond 
the scope of predefined pathways are needed.            
 
   121                                     However, 
the scope of previous studies has been restricted to a s
 
   122 nd computational power have greatly expanded 
the scope of problems that VB theory can address.       
 
   123                       This chemistry expands 
the scope of products that can be prepared from terminal
 
   124 brary of reference spectra, thereby limiting 
the scope of products that can be screened.             
 
   125 protein hydrogels could significantly expand 
the scope of protein hydrogels in biomedical application
 
   126 mediated affinity labeling approach broadens 
the scope of PTM detection by chemical means and may fac
 
   127          Our unpredictability metric expands 
the scope of quantitative biomechanical studies to inclu
 
   128 bstrate promiscuity and protein engineering, 
the scope of reactions catalysed by native metalloenzyme
 
   129                                              The scope of reactions that form C-C bonds or install fu
 
   130                                    Expanding 
the scope of recent NMR and computational studies, we ex
 
   131 e anticipate that these findings will expand 
the scope of research on biological mechanisms that prom
 
   132 mportance, and this will undoubtedly broaden 
the scope of research on the chemistry of doping and cry
 
   133 tant organs, which is important for planning 
the scope of resection and further treatment, graft impl
 
   134 tant insights into RNA structure and widened 
the scope of RNA studies.                               
 
   135                          We find that within 
the scope of scenarios broadly-consistent with the WG3 d
 
   136 evelopments in 2D IR that continue to expand 
the scope of scientific problems that can be accessed in
 
   137                     BRIE, therefore, expands 
the scope of scRNA-seq experiments to probe the stochast
 
   138 al range size was positively correlated with 
the scope of seasonal temperature variation, whereas ele
 
   139           Overall, the present study expands 
the scope of shape-persistent macrocycles to include fle
 
   140 re can be achieved sustainably provided that 
the scope of SI expands to encompass environmental weed 
 
   141                                  They extend 
the scope of small molecule substrates prone to such coo
 
   142 ing Meisenheimer complex formation, limiting 
the scope of SNAr reactions: the most common SNAr substr
 
   143                    Here, results that expand 
the scope of solid-phase peptide synthetic methodology t
 
   144 historical trends of cultural centers beyond 
the scope of specific events or narrow time intervals.  
 
   145                               Here we expand 
the scope of SRM to photoactivated localization microsco
 
   146  Herein we report a significant expansion to 
the scope of substitution reactions for the dodecaborate
 
   147      This information is needed to determine 
the scope of such care, its contributions to global surg
 
   148                                     To date, 
the scope of such novel technologies is limited and may 
 
   149 nto global health initiatives do not reflect 
the scope of surgical need and many health systems do no
 
   150                    Our goal was to summarise 
the scope of surgical task-shifting in LMICs through a s
 
   151                                       Within 
the scope of synthetic biology, carboxysomes and other B
 
   152 t the use of derivatization reactions widens 
the scope of targeted molecules but also clearly points 
 
   153 ese principles and classic predictions about 
the scope of TCR cross-reactivity.                      
 
   154                                              The scope of temperate AC research and application has b
 
   155            This nano-gating membrane expands 
the scope of temperature-responsive membranes and has gr
 
   156                                    Recently, 
the scope of testing has increased to include selected s
 
   157                                     However, 
the scope of that control remains unknown: it remains un
 
   158                                 In addition, 
the scope of the [3 + 2]-annulation was evaluated and en
 
   159                           The authors review 
the scope of the abuse and overdose epidemic, prescripti
 
   160     Increasing the structural complexity and 
the scope of the accessible structures is an outstanding
 
   161                                              The scope of the acetone-linked peptides was further exp
 
   162                                              The scope of the alkyne and hydrosilane partners is subs
 
   163                         These results extend 
the scope of the already very versatile Suzuki-Miyaura r
 
   164                       This article discusses 
the scope of the antibiotic misuse in surgery for surgic
 
   165                                              The scope of the applications of breath sensors is abund
 
   166                               After defining 
the scope of the article, which excludes anionic and mos
 
   167                                              The scope of the aziridine ring-opening reaction was sub
 
   168 h threats as contaminants, and understanding 
the scope of the biochemical interactions involved in ac
 
   169                                              The scope of the catalysis is tested by employing a seri
 
   170                                              The scope of the chirality transfer [2+2] cycloaddition 
 
   171       The recommendations concern: expanding 
the scope of the current guideline; requirements to asse
 
   172                                              The scope of the current methodology was further extende
 
   173                                              The scope of the current work was the development of a h
 
   174  range of aldehydes were employed to examine 
the scope of the cyclization.                           
 
   175                                  We expanded 
the scope of the database by including somatic mutations
 
   176  of two interatomic potentials and to extend 
the scope of the DFT studies.                           
 
   177 alized heterocycles, while further expanding 
the scope of the distortion/interaction model.          
 
   178                          Our results broaden 
the scope of the ecomorphological diversification of Mes
 
   179 athogenesis, and transmission potential, and 
the scope of the epidemic was largely hidden, owing to g
 
   180 ic testing hampers our ability to understand 
the scope of the epidemic, implications for vaccine impl
 
   181  it to verification of this claim, extending 
the scope of the experiment to various complex networks 
 
   182 with wastewater reuse for agriculture within 
the scope of the FEW nexus and propose strategies for cl
 
   183 y of phenotypic variation, greatly narrowing 
the scope of the functional genome.                     
 
   184 on campaigns while paying close attention to 
the scope of the geographic extension of the campaigns. 
 
   185 pid Guideline Development Work Group defined 
the scope of the guideline, gathered evidence, determine
 
   186 ents with low bone mineral density is beyond 
the scope of the guideline.                             
 
   187      Here, we used RNA sequencing to uncover 
the scope of the H2O2 (peroxide)-stress regulon and to f
 
   188 ful in a clinical setting, especially within 
the scope of the increasing use of eye-salvage treatment
 
   189                        These results broaden 
the scope of the invariant recognition framework for und
 
   190                          This method extends 
the scope of the library to include spectra of "nearest-
 
   191 ave been incorporated to widen and diversify 
the scope of the light-driven liquid crystalline materia
 
   192 ancomycin-resistant enterococci (VRE) due to 
the scope of the medical threat posed by these pathogens
 
   193                                              The scope of the method was enlarged to 35 GC and 63 LC 
 
   194                                              The scope of the method was investigated and aromatic, a
 
   195                                 To determine 
the scope of the method, protein pharmaceuticals of diff
 
   196                               To demonstrate 
the scope of the method, the assembly of a set of bivale
 
   197                                              The scope of the methodology becomes apparent from 14 ex
 
   198               A novel protocol for extending 
the scope of the Mitsunobu reaction to include amine nuc
 
   199                                              The scope of the modular platform is illustrated by prep
 
   200 n of massive sequencing data has illuminated 
the scope of the mutational burden in cancer genomes, id
 
   201                                              The scope of the new method for the synthesis of 2H-1,4-
 
   202 , the extent of donor and recipient consent, 
the scope of the obligation that the organization has to
 
   203                                       Due to 
the scope of the outbreak combined with the lack of avai
 
   204         Collectively, our findings unraveled 
the scope of the peroxide stress regulon and expand the 
 
   205 from 1 generic to another, initiated outside 
the scope of the prescriber, must be avoided as they are
 
   206 ith phosphate amendments is a viable option, 
the scope of the problem and conditions in urban setting
 
   207 ic health care network, a better estimate of 
the scope of the problem can be obtained.               
 
   208 hould be sensitizing in the case of Yb(III); 
the scope of the process extends to Ln(III) for which it
 
   209                                              The scope of the process is explored, demonstrating effi
 
   210                                              The scope of the propargylic amination to yield opticall
 
   211                                              The scope of the protocol in organic synthesis has been 
 
   212                                   To enlarge 
the scope of the PubAngioGen application, our database a
 
   213                                              The scope of the radical precursor includes alpha-iodo k
 
   214                                              The scope of the reaction has been successfully tested w
 
   215                                    Moreover, 
the scope of the reaction is demonstrated through protei
 
   216                                              The scope of the reaction is limited to unbranched aliph
 
   217                                              The scope of the reaction is quite broad, tolerating a v
 
   218                                              The scope of the reaction is quite decent, allowing for 
 
   219                                              The scope of the reaction is very broad with respect to 
 
   220                                              The scope of the reaction was achieved from 6-(2-aminoph
 
   221                                              The scope of the reaction was demonstrated.             
 
   222                 On the basis of this result, 
the scope of the reaction was extended to the synthesis 
 
   223                                              The scope of the reaction was studied by varying the ald
 
   224 to possess enhanced reactivity, has expanded 
the scope of the reaction while maintaining a high level
 
   225                                   To explore 
the scope of the reaction, 20 different 1,3-diazabicyclo
 
   226                             As an example of 
the scope of the reaction, four 1,5-shift reactions have
 
   227                                              The scope of the reaction, using symmetric and unsymmetr
 
   228 together with some suggestion for increasing 
the scope of the reaction, with special attention to the
 
   229                                              The scope of the reductive isomerization was investigate
 
   230                                              The scope of the reforms should address failures in the 
 
   231  that can generate secondary findings beyond 
the scope of the research.                              
 
   232                                              The scope of the review covers multiscale materials and 
 
   233 he methods used to measure, and the scale of 
the scope of the studies means that no general picture c
 
   234 ional efforts culminated in the expansion of 
the scope of the substitution to various heteroatom-base
 
   235         This transformation greatly improves 
the scope of the TMM cycloaddition technology and provid
 
   236 eterocycles were studied in order to broaden 
the scope of the transformation in synthetically interes
 
   237                                              The scope of the transformation is wide, and the limitat
 
   238 n has hitherto limited their general use and 
the scope of the transformation.                        
 
   239 tion models of category learning and broaden 
the scope of the transitive inference paradigm.SIGNIFICA
 
   240 cess to nonstandard amino acids by expanding 
the scope of the translational apparatus.               
 
   241 ng systems and emphasize the need to broaden 
the scope of the underlying data.                       
 
   242 uring government officials to severely limit 
the scope of the work.                                  
 
   243 ree to which the programs may be privatized, 
the scope of their cost-sharing structures for beneficia
 
   244  have a relatively low output power limiting 
the scope of their potential applications.              
 
   245 small-molecule screening library, depends on 
the scope of their protein interactions in cells, a para
 
   246 ts are milder, but their low basicity limits 
the scope of their reactions.                           
 
   247                  To determine quantitatively 
the scope of these "losses by design", we have assessed 
 
   248                                      Despite 
the scope of these changes, backwards compatibility is m
 
   249                         To better understand 
the scope of these changes, we recorded from pairs of mo
 
   250                                    To expand 
the scope of these processes to gas streams containing v
 
   251 en considerable recent interest in expanding 
the scope of these reactions by developing new catalysts
 
   252                                              The scope of these reagents for various organic transfor
 
   253                                              The scope of these relay cyclizations has been dramatica
 
   254 ic and ecological impacts, but understanding 
the scope of these requires quantitative information on 
 
   255                                              The scope of these studies has gradually expanded to inc
 
   256                                              The scope of these transformations is discussed as well 
 
   257                              This was beyond 
the scope of this article.                              
 
   258 aditionally resistant substrates, broadening 
the scope of this asymmetric Nazarov cyclization.       
 
   259 nterrupted Cope rearrangements and expanding 
the scope of this classic reaction to the design of new 
 
   260                                              The scope of this COS includes clinical effectiveness tr
 
   261                                              The scope of this design concept is explored by studying
 
   262  and luciferin can be reengineered to extend 
the scope of this light-emitting reaction.              
 
   263                                              The scope of this meta-selective borylation is demonstra
 
   264                                   Studies of 
the scope of this method revealed that cages containing 
 
   265                  Eventually, we extrapolated 
the scope of this methodology to the formal total synthe
 
   266                                              The scope of this methodology was demonstrated with a ra
 
   267                                     However, 
the scope of this modification both in bacteria and in e
 
   268                                    Moreover, 
the scope of this myoglobin-mediated transformation coul
 
   269                                              The scope of this novel transformation was studied in te
 
   270                                              The scope of this one-pot coupling has been also extende
 
   271 istinct axon guidance receptor families, but 
the scope of this overlap is unclear, as is the impact o
 
   272 avoid or limit the artifacts would go beyond 
the scope of this paper but technical ways to reduce the
 
   273                                              The scope of this reaction is demonstrated with highly e
 
   274                         Aside from surveying 
the scope of this reaction, we provide details about the
 
   275                                              The scope of this review article is to discuss the local
 
   276                                              The scope of this review has been limited to well-charac
 
   277                                              The scope of this review includes the modeling and simul
 
   278                                              The scope of this review is to assess systematically the
 
   279                                              The scope of this review ranges from the purely fundamen
 
   280  opposed to N-functionalization) are outside 
the scope of this review.                               
 
   281 of translation may not have been captured by 
the scope of this review.                               
 
   282  and cessation, this is a large topic beyond 
the scope of this Seminar.                              
 
   283                                              The scope of this statement will extend beyond the reach
 
   284                                              The scope of this strategy encompasses a series of enant
 
   285 compendium has revealed 13 terms relevant to 
the scope of this study.                                
 
   286                                    We define 
the scope of this survey and a classification schema fir
 
   287 FM available to only a few groups worldwide, 
the scope of this technique is unnecessarily limited.   
 
   288 ical labeling, should significantly increase 
the scope of this technology.                           
 
   289 nalization of enol ethers was developed, and 
the scope of this transformation was explored.          
 
   290  were observed for earlier probes, expanding 
the scope of this type of probe beyond Hg(2+) detection.
 
   291                                              The scope of this unprecedented enzymatic approach to no
 
   292                                              The scope of this unusual reaction has been investigated
 
   293                                       Hence, 
the scope of this workshop was to determine the basic fu
 
   294                           This study expands 
the scope of translating mussel adhesion from simple Dop
 
   295 ional holidays are associated with shifts in 
the scope of travel.                                    
 
   296 otential and novel modes of action, to widen 
the scope of treatment and to overcome emerging drug res
 
   297  that 90% of the papers in PubMed are out of 
the scope of UniProt, that a maximum of 2-3% of the pape
 
   298           These results significantly expand 
the scope of using functionalized benzotriazinyls as sta
 
   299 are the strengths and weaknesses, as well as 
the scopes, of various bioinformatics tools.            
 
   300 As a consequence, the key steps that control 
the scope of viable substrates and various aspects of se