ライフサイエンスコーパス: the specificity of

1 mmography in patients with dense breasts and the specificity of 2D mammography for all subgroups.

2 The specificity of (64)Cu-CBP7 for collagen was confirme

3 Herein, we investigated the specificity of 666-15 and evaluated its potential in

4 The specificity of (68)Ga-PSMA HBED-CC PET and morpholog

5 The specificity of (89)Zr-DFO-AC-10 binding to CD30 in v

6 The specificity of (99m)Tc-duramycin for apoptosis was a

7 In the present study, we examined the specificity of a broad and potent cross-neutralizing

8 The specificity of a CSF-TPPA titer of >/=1:640 was sign

9 Substitutions at this position change the specificity of a diverse panel of environmental TraA

10 modulatory protein was created that combines the specificity of a HIV-1 broadly neutralizing antibody

11 e the flexibility of chemical synthesis with the specificity of a programmable DNA-binding protein by

12 Calcium plays a key role in determining the specificity of a vast array of signalling pathways i

13 CD studies demonstrated the specificity of A-ZIP53 as it did not interact with b

14 The specificity of ABCG37 for individual coumarins was f

15 y parallel enzyme kinetics analysis detailed the specificity of ADAMTS13 and demonstrated the critica

16 s with asthma was 66.7% (10/15 subjects) and the specificity of adult healthy volunteers was 86.7% (1

17 The specificity of AF-353 for P2X3-containing receptors

18 The specificities of all the criteria were >/=90%, with

19 The specificity of all 3 radioligands for tau aggregates

20 itivity of the single dimension measure, but the specificity of all response measures (ability to ide

21 e its role, along with the MHC, in directing the specificity of allorecognition.

22 The specificities of anti-F IgG induced by the two mutan

23 These results reveal incomplete overlap in the specificities of antibodies that mediate these antiv

24 PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with

25 y specific and highly sensitive by combining the specificity of antibody staining and the sensitivity

26 remaining challenge is to increase and guide the specificities of anticancer immune responses, e.g.,

27 The specificity of AR extends to the regions flanking th

28 vealing the structure features important for the specificity of ATR inhibitors.

29 three regulatory mechanisms contributing to the specificity of ATXR5/6.

30 hat the motifs contributing significantly to the specificity of binding follow the previously propose

31 The specificity of binding was verified with a non-impri

32 Here, we compare the specificities of bNAbs and nNAbs to demonstrate that

33 sequencing, GROC-SVs substantially improves the specificity of breakpoint detection at comparable se

34 Conclusion OA/US increases the specificity of breast mass assessment compared with

35 epends on the affinity towards PDE6delta and the specificity of cargo release.

36 The specificity of CBM32 has been further elucidated by

37 ts ability to recognize diverse ligands, and the specificity of CC and CXC receptors for their respec

38 The specificity of CD in mediating alterations of the EC

39 However, less is known about the specificity of CD4+ TH responses, and whether differ

40 ctions provides a novel mechanism to sharpen the specificity of cell-cell interactions.

41 discuss have particular potential to combine the specificity of cellular-level measurements with the

42 This proxy resources to the specificity of cerium to adopt both the +III and +IV

43 cell development, recent advances regarding the specificity of chemokine signaling, and novel techni

44 The peptide-receptor relationships determine the specificities of CLE-dependent signals controlling s

45 RHBDL2 in human endothelial cells validated the specificity of CLEC14A shedding by RHBDL2.

46 e of artifact correction logic would improve the specificity of clinical event detection without comp

47 The specificity of CNV detection on OCTA compared with F

48 and reveals the interactions responsible for the specificity of CobK.

49 The specificity of coiled-coil dimer pairing is mainly b

50 se long-range inhibitory projections enhance the specificity of contextual and object memory encoding

51 The specificity of cortical activation can be considered

52 on of this genetic system largely depends on the specificity of Cre recombinase expression in targete

53 rect for this copy number effect, increasing the specificity of CRIPSR screens to identify essential

54 To evaluate the specificity of current definitions used to identify

55 mRNA in patient urine samples could improve the specificity of current PCa diagnosis.

56 We were able to increase the specificity of DeepSNV to >99.95% by applying an emp

57 The specificities of Determine, SD-Bioline, and Uni-Gold

58 We examined the specificity of different cyclin E antibodies and eva

59 red regions to enhance the affinity and tune the specificity of DNA interactions in tandem with a glo

60 nd rapid gene fusion strategy which expliots the specificity of DNA ligase and the speed of isotherma

61 rent CESA proteins and hence what determines the specificity of each CESA class.

62 yphimurium, and E. coli were used to confirm the specificity of each probe-set, and serial 10-fold di

63 different proteasome subcomplexes, explains the specificity of Ecm29 for proteasome holoenzymes.

64 Our results help explain the specificity of Eco 6S RNA for Esigma(70) and show ho

65 crossmodal pattern classification to assess the specificity of EEG mu rhythm response to action vary

66 The specificity of effector-associated gene induction an

67 The specificity of en face OCTA alone was 92.5% for grad

68 The specificity of encapsidation of C-cluster enteroviru

69 We have previously shown that the specificity of encapsidation of poliovirus and of C-

70 veloped to assist investigators in exploring the specificity of epigenomic features across selected t

71 ther, our data demonstrate that TMM dictates the specificity of ERfs for the perception of different

72 t artifact correction significantly improved the specificity of event detection without decreasing se

73 However, determining the specificity of executive dysfunction across these di

74 se a mechanism to explain how Rad53 enhances the specificity of FHA1-mediated transient interactions.

75 The specificity of findings to tonic, but not faster, mo

76 nding of how G-proteins are regulated and of the specificity of G-protein interactions with their reg

77 The specificity of GCAP binding imparted by RetGC1 dimer

78 To increase the specificity of GSK-3beta inhibitors in chronic treat

79 equencies after receipt of the IIV reflected the specificity of high-affinity antibody production.

80 The specificity of high-risk breast screening improved a

81 or next-generation sequencing that harnesses the specificity of HIV-directed priming to enable full g

82 ng the Hoxa1 and TALE genes, indicating that the specificity of HOXA1 during development may be regul

83 by providing a quantitative explanation for the specificity of hypoxanthine-guanine phosphoribosyltr

84 oral manipulations, NTBS protocols can reach the specificity of imaging techniques.

85 This approach extends the specificity of immunocapture to metal affinity magne

86 clinical practice CCDs often interfere with the specificity of in vitro allergy diagnostics, thus im

87 It provides a useful model in which to test the specificity of in vivo binding of the putative tau l

88 icroarrays was then exploited to deconvolute the specificities of individual mAbs.

89 he modification of tail-region substituents, the specificity of inhibition for SphK1 and SphK2 could

90 The current experiments address the specificity of inhibitory mechanisms, asking whether

91 ine, SD-Bioline, and Uni-Gold were 100%, and the specificity of INSTI was 99.8%.

92 The specificity of interaction between PvTRAg38 and basi

93 The specificity of interim PET/CT based on RIW criteria

94 The specificity of IPCA was 0.96 for clinical images and

95 ions of these proteins and new insights into the specificities of ISG actions.

96 reathing motions of adjacent layers revealed the specificity of isotope engineering in a layered mate

97 The results demonstrate that the specificity of KMTs is highly sensitive to the side

98 s on methodological developments to increase the specificity of knowledge obtained regarding brain fu

99 Targeting experiments confirmed the specificity of labeled antibody to CD56+ cells.

100 Thus, the specificity of LacY for sugar is determined solely b

101 tivity within premotor circuits, but whether the specificity of learning depends on structured change

102 olipid headgroups is a simple way to control the specificity of lipid extraction from membranes by pe

103 The specificity of LPCAT1 for lyso-PC as an acyl accepto

104 In this work, we report the specificity of MALDI-TOF MS for the identification o

105 ics and pharmacological approaches confirmed the specificity of MEcPP in RSRE induction via the trans

106 The specificity of MEcPP is further confirmed by the lac

107 ve synapses is thought to be detrimental for the specificity of memory storage.

108 dicative of reduced brain uptake, confirming the specificity of MFSD2A for LPCs having mono- and poly

109 Phosphorylation at Ser-386 does not switch the specificity of Mgc's GAP activity and is not require

110 eventing off-target embolization, increasing the specificity of microsphere delivery, and reducing th

111 To control the specificity of MIPs, a different antibiotic enroflox

112 tly, serious concerns have been raised as to the specificity of MO effects, and it has been recommend

113 TRT combines the specificity of molecular and sometimes physical targ

114 The specificities of MRI versus CT (0.91 versus 0.92) an

115 signature." Thalamic WNT3 further regulates the specificity of mRNA translation and development of n

116 ation elongation factor 1alpha [eEF1A]) aids the specificity of Msn5 for aminoacylated tRNAs to form

117 sue penetration of small-molecule drugs with the specificity of much larger protein therapeutics.

118 Additionally, the specificity of mutant proteins, with variants of ami

119 Overall, these data demonstrate the specificity of neuronal circuit changes induced by a

120 veal a novel cellular mechanism that ensures the specificity of neuronal kinase signaling.

121 The specificity of nucleic acid amplification tests (NAA

122 exible-loop insertion, which may account for the specificity of one enzyme for substrates delivered b

123 Our results show how the specificity of one RBP (Pum) is modulated by coopera

124 nformation and identify key interactions for the specificity of ORF112.

125 The specificity of our cccDNA probe set was confirmed by

126 d the proliferative phenotype, demonstrating the specificity of our epigenetic targeting.

127 eral interactions by reverse co-IP, supports the specificity of our screening process.

128 d, partly due to difficulties in determining the specificity of P-TEFb toward the various heptad repe

129 trans-interacting partner residues, altered the specificities of Pcdh interactions.

130 A-binding specificity and RNA-seq to measure the specificity of perturbing the transcriptome.

131 o CA1 synapses, but there are concerns about the specificity of PKC activators and inhibitors.

132 cal role in regulating both the kinetics and the specificity of PME.

133 The specificity of posttreatment PET/CT (Deauville) was

134 -for example, the difficulty in establishing the specificity of postulated associations.

135 The specificity of presynaptic and postsynaptic interact

136 ly targets long transposable elements due to the specificity of primary small RNAs to cleave full-len

137 ess typically influence kinetics rather than the specificity of prion conversion.

138 ), TMS8 (W351F), and TMS10 (T414S) broadened the specificity of PrnB, enabling it to recognize more e

139 The specificity of probes was investigated on DNA microa

140 nt peptide hormone maturation are scarce and the specificity of processing enzyme(s) is largely unkno

141 TERS combines the specificity of Raman spectroscopy with the high spat

142 ity against FR-negative cells, demonstrating the specificity of redirection by folate-FITC.

143 the G-protein cycle itself may contribute to the specificity of response regulation in plants by affe

144 mework emphasizes the common links, but also the specificities of responses to drivers and the ecosys

145 Furthermore, these results illustrate the specificity of retinal connections, which cannot be

146 the 2 legs opposite one another, can explain the specificity of Rev for the RRE.

147 We used the amino acid code governing the specificity of RNA binding by PPR repeats to infer c

148 challenge for the field will be to elucidate the specificities of Rpn11, Usp14, and Uch37 in greater

149 ing compact RNA structures without improving the specificity of self-assembly.

150 ribe a technology (BiSeqS) that can increase the specificity of sequencing by at least two orders of

151 nfirm positive results in the VLP-MAC-ELISA, the specificity of serodiagnosis, especially for JEV inf

152 ation may exist, which likely contributes to the specificity of signal-response coupling.

153 To address the specificity of SM transport to the plasma membrane,

154 cities in vitro, contrary to the claim about the specificity of some Ate1 isoforms for N-terminal Cys

155 en alga Chlamydomonas reinhardtii to examine the specificity of spatial and temporal dynamics of Ca(2

156 ucture-guided protein engineering to improve the specificity of Streptococcus pyogenes Cas9 (SpCas9).

157 The specificity of structural OCT alone was 97.5% for gr

158 Here, we investigate the specificity of subcritical water with respect to the

159 play a role in either process, demonstrating the specificity of subdistal appendages for these events

160 However, mechanisms contributing to the specificity of such interactions remain poorly under

161 edge, this is the first study to demonstrate the specificity of such modifications in a defined motor

162 The specificity of such Pumby-RNA interactions was high,

163 e implement an electrochemical setup and use the specificity of superoxide dismutase-1 (SOD1) to show

164 We recently demonstrated the specificity of surface-induced amyloidogenesis but t

165 disease requires a detailed understanding of the specificity of T cells for gluten.

166 In this study, we redirected the specificity of T cells to SLAMF7 through expression

167 synthetic fusion proteins that can redirect the specificity of T cells toward designated antigens.

168 ADS domain protein complexes plays a role in the specificity of target gene regulation.

169 However, questions remain about the specificity of target site recognition.

170 The specificity of TF imaging with (64)Cu-NOTA-FVIIai wa

171 activity likely plays a role in establishing the specificity of thalamocortical connectivity and the

172 orting, and deep sequencing, we have defined the specificities of the first two kinases in this pathw

173 e profiling method to uncover differences in the specificities of the human and P. falciparum proteas

174 umors grown in wild-type mice, demonstrating the specificity of the (18)F tracer for MMR and macropha

175 t in different ROS signatures that determine the specificity of the acclimation response and help tai

176 The specificity of the activity was confirmed with a Nan

177 In particular, the specificity of the additional information provided b

178 k for schizophrenia and depression confirmed the specificity of the Alzheimer's disease polygenic ris

179 The specificity of the Amy13K CBMs provides a molecular

180 r sensor specificity change through altering the specificity of the aptamer.

181 The specificity of the assay was evaluated with nonglyca

182 The specificity of the assay was tested with EDTA plasma

183 The specificity of the assay with respect to other prote

184 the skin tests or the IgE assays, confirming the specificity of the assay.

185 restricted inclusion of non-CP-CRE to assess the specificity of the assays.

186 s to kill autoreactive B lymphocytes through the specificity of the B cell receptor (BCR).

187 The current understanding of the specificity of the bacterial class I release factors

188 sylases preserve genome integrity and define the specificity of the base excision repair pathway for

189 th sensitivity set at 85% for a triage test, the specificity of the best 3-antigen model was 34% (95%

190 The specificity of the biomarker suite was 94%.

191 The specificity of the biosensor was tested against four

192 dition of a supplemental immunoblot improved the specificity of the C6 EIA to 98.6%.

193 c CD4(+) T cell memory, we hypothesized that the specificity of the CD4(+) T cell response was a crit

194 The specificity of the CHIR-AIV interaction was further

195 and unfavorable effects of LXR by exploiting the specificity of the coactivator thyroid hormone recep

196 ow these associations are acquired, or about the specificity of the conditioned response modalities.

197 cellular uptake in 3D culture, demonstrating the specificity of the construct.

198 elationships (QSARs), but they improved with the specificity of the descriptor.

199 e intensive sequence of testing in GB, it is the specificity of the DIVA test, rather than the sensit

200 Additionally, the specificity of the drug action on A20 was confirmed

201 by PT2399 in resistant tumours, illustrating the specificity of the drug.

202 ly specific responses, respectively, showing the specificity of the early left hemispheric dominance

203 xact role of the four amino acid residues in the specificity of the enzymes is still unresolved.

204 y critical molecular determinants that drive the specificity of the epsin and VEGFR2 interaction and

205 The specificity of the evaluated MAbs, P1B1 and P4W2 wer

206 The specificity of the folding landscape is further enha

207 Despite the specificity of the fuel composition, emission ratios

208 s provide sufficient contrast to: 1) analyze the specificity of the histamine receptor subtypes for d

209 elated Hsp60 altered TH activity, confirming the specificity of the Hsc70 effect.

210 To show the specificity of the ICA, we produced Ag-specific Abs

211 se of binding antibody responses and altered the specificity of the IgG responses, correlating with t

212 y increased sensitivity without compromising the specificity of the immunoassay.

213 The specificity of the immunosensor was inspected by det

214 es in vigilant attention, as corroborated by the specificity of the influence of a genetic biomarker,

215 Immunoprecipitation analysis confirmed the specificity of the interaction between Munc13-4 and

216 This pattern of results confirms the specificity of the interaction between oxytocin and

217 The specificity of the interaction between the TCR heter

218 Making use of the specificity of the IR spectral range, we are able to

219 y of Gtfs and S. mutans biofilms, signifying the specificity of the lead compound.

220 thereby preclude obtaining information as to the specificity of the leaving group and therefore the m

221 cell RNA-Seq data for a case of melanoma and the specificity of the ligand-receptor interactions and

222 The specificity of the majority of the members of RHOGAP

223 ation of Smk1 on Y209 also appears to modify the specificity of the MAPK by suppressing Y kinase and

224 eous detachment from the hippocampus reduces the specificity of the memory.SIGNIFICANCE STATEMENT Thi

225 Perfect and mismatch probes established the specificity of the microarray in sewage, and fluores

226 ndividuals, what is currently unclear is how the specificity of the molecular response is modified by

227 earch has failed to convincingly demonstrate the specificity of the mu rhythm, meaning that it is unc

228 the clinical features of disease to increase the specificity of the new criteria for underlying PSP p

229 The specificity of the NF-kappaB-luciferase signal to th

230 e, enabling pharmacological interrogation of the specificity of the offspring response.

231 The specificity of the peptide reporter was evaluated an

232 (PMEIs; 76 members in Arabidopsis) questions the specificity of the PME-PMEI interaction and the func

233 Although this interaction defines the specificity of the pollen rejection response, the id

234 The specificity of the proposed magnetic probes toward E

235 e disorders provide a basis for re-examining the specificity of the prospective association of manic

236 In summary, the specificity of the proteasome can be regulated by ra

237 We further refined the specificity of the proteins identified by combining

238 The specificity of the scoring function that we use is d

239 The specificity of the sensor was designed to address th

240 The specificity of the sensor was examined by blind test

241 The specificity of the sensor was validated by performin

242 r imprinted layer reported first time boosts the specificity of the sensor.

243 ylbenzene, and diisopropylbenzene) highlight the specificity of the shape selectivity exhibited by CD

244 The specificity of the signal was demonstrated by blocki

245 gaps regarding the fate of seeds in soil and the specificity of the soilborne fungi that are their mo

246 However, the specificity of the species barrier is primarily affe

247 nisms underpinning disease manifestation and the specificity of the subunits mutated are incompletely

248 raged locomotor characteristics must reflect the specificity of the task and the neurological states.

249 The specificity of the test, detecting the absence of si

250 The specificity of the transmission of depression across

251 ific platform for conjugation that relies on the specificity of the transpeptidase Sortase A (SrtA) f

252 The specificity of the TST was 69% (95% CrI: 63%, 76%).

253 A preliminary analysis of the specificity of the two most active peptides indicate

254 he antibody for the target ligand determines the specificity of therapeutic delivery and off-target s

255 The specificity of these antibodies for the normal form

256 at and contain the commensal microbiota, yet the specificity of these antibodies remains elusive.

257 The specificity of these antibodies was concomitantly in

258 The specificity of these cellular changes for virus-indu

259 Metabolic rescue experiments confirm the specificity of these effects and demonstrate that un

260 However, the specificity of these effects is unknown.

261 nal deployment early in the etiology of ASD, the specificity of these effects to ASD remains to be de

262 We demonstrate here that the specificity of these enzymes for their substrates is

263 we demonstrate that we can predictably alter the specificity of these factors in vivo.

264 We further demonstrate the specificity of these inhibitors for FGF2 because tyr

265 cellular processes, but the rules governing the specificity of these interactions are poorly underst

266 s, yet our ability to accurately re-engineer the specificity of these interactions using computationa

267 from uninjured adult mice, thereby limiting the specificity of these markers in inducible models (e.

268 We demonstrate the specificity of these membrane interactions and the d

269 leoprotein (RNP) complex that is critical to the specificity of these small molecules for SMN2 over o

270 Combining the specificity of these three methodologies is of great

271 The specificity of these viral protein-FND conjugates to

272 n in the anaesthetised rat brain, supporting the specificity of this approach in the study of altered

273 ) necessary to produce pyocyanin, supporting the specificity of this biomarker.

274 imetic which reveals the molecular basis for the specificity of this cognate E2/RBR E3 pair.

275 E2 Ub in an open conformation and explains the specificity of this cognate RBR E3/E2 pair.

276 The specificity of this convergent architecture to these

277 The specificity of this effect for different divalent io

278 hanges in WT binding of (18)F-AV45 undermine the specificity of this effect.

279 Attesting to the specificity of this finding, self-esteem was predict

280 The specificity of this immunosensor was tested using ot

281 The specificity of this increase may be related to the d

282 As further illustration of the specificity of this phenomenon, serum collected from

283 Further analyses investigated the specificity of this prediction.

284 The specificity of this proposed method to detect nitrit

285 The specificity of this transport was highlighted by the

286 We analyzed the specificity of three IGHV4-34*01 IgG antibodies isol

287 inimal chemical difference that can modulate the specificity of TMD interactions and the activity of

288 th concurrent training within the context of the specificity of training adaptation.

289 The specificities of transcription factors are most comm

290 e sequence and structural elements governing the specificity of TRUB1, achieving near-perfect predict

291 ike nuclease-proficient Cas9 in human cells, the specificity of truncated gRNAs (18 nt of complementa

292 The specificity of Tunisian VOOs was evaluated by compar

293 We characterized the specificities of two proteasome-associated deubiquit

294 n residues was also identified as modulating the specificity of type I cohesin-dockerin interactions

295 The specificity of unipolar EMB was better than bipolar

296 To delineate the specificity of vaccine-elicited cross-reactive tier

297 Finally, we confirmed the specificity of VU590 action by inhibition of native

298 Our findings show that the specificity of WD40-bHLH-MYB complexes is in part de

299 epends on interactions between TCS proteins, the specificity of which is poorly understood.

300 The specificity of within-normal-limits global classific