ライフサイエンスコーパス: theaflavin

1 atments of the tea polyphenols EGCG, GCG and theaflavins.

2 involved in the inhibition by catechins and theaflavins.

3 of 14 tested polyphenols, tannic acid (TA), theaflavin-3'-gallate (TF2B) and theaflavin-3,3'-digalla

4 lyphenols, theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate (TF

5 Theaflavin-3,3'-digallate (TFdiG), theaflavin-3'-gallate, theaflavin-3-gallate, and theafla

6 aflavin (TF-1), theaflavin-3-monogallate and theaflavin-3'-monogallate mixture (TF-2), and theaflavin

7 heaflavin-3'-monogallate mixture (TF-2), and theaflavin-3,3'-digallate (TF-3) are the major black tea

8 acid (TA), theaflavin-3'-gallate (TF2B) and theaflavin-3,3'-digallate (TF3) exhibited inhibitory eff

9 cells were treated with Hcy, BT extract, and theaflavin-3,3'-digallate (TF3).

10 ith (-)-epigallocatechin-3-gallate (EGCG) or theaflavin-3,3'-digallate (TFdiG) (20 mM) for different

11 Theaflavin-3,3'-digallate (TFdiG), theaflavin-3'-gallate

12 flavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate (TFdiG), were compared with re

13 3'-digallate (TFdiG), theaflavin-3'-gallate, theaflavin-3-gallate, and theaflavin inhibited PL with I

14 mers, and black tea polyphenols, theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate, and theafla

15 Theaflavin (TF-1), theaflavin-3-monogallate and theaflavin-3'-monogallate m

16 We determined the effects of theaflavin, a black tea-derived polyphenol, on tumor nec

17 Theaflavin also significantly reduced tumor necrosis fac

18 that inhibited cell transformation, EGCG and theaflavins also inhibited AP-1-dependent transcriptiona

19 ls were exposed to varying concentrations of theaflavin and analyzed for tumor necrosis factor-alpha-

20 mpared the inhibitory efficacy of individual theaflavins and explored the underlying mechanism.

21 ack tea involves oxidation of catechins into theaflavins and other complex phenolics by endogenous en

22 had high levels of total thearubigins, total theaflavins and theaflavin fractions.

23 ating that catechins in green tea as well as theaflavins and thearubigins from black tea are the subs

24 Although black tea, which contains theaflavins and thearubigins, is widely consumed in the

25 kaempferol-3-O-glucosyl-rhamnosyl-glucoside, theaflavin, and theobromine.

26 (-)-Epigallocatechin gallate (EGCG) and theaflavins are believed to be key active components in

27 The detection limits for catechins and theaflavins are from 5 to 10 ng/ml of saliva, plasma, or

28 t to the active site, and galloyl-containing theaflavins are then predicted to perturb the protonatio

29 at certain green tea catechins and black tea theaflavins are very potent inhibitors (K(i) in the nano

30 ossible to determine the major catechins and theaflavins as well as some of the catechin metabolites.

31 the anti-tumor promotion effects of EGCG and theaflavins at the molecular level.

32 In silico modeling showed that theaflavins bind to Asn263 and Asp206, which form a pock

33 , the molecular mechanisms by which EGCG and theaflavins block carcinogenesis are not clear.

34 ract, tyrosinase increased the proportion of theaflavins by twofold compared to black tea.

35 dase used were important factors determining theaflavin concentrations.

36 catechin with tyrosinase gave a high, stable theaflavin content.

37 dation process was directed towards a higher theaflavins content, which is considered an important qu

38 ermine the individual and total catechin and theaflavin contents by HPLC and the total antioxidant ca

39 ults show that the polyphenol (catechins and theaflavins) contents were significantly influenced by p

40 ent transfections demonstrated that EGCG and theaflavins could repress the transcriptional activities

41 of total thearubigins, total theaflavins and theaflavin fractions.

42 of the levels of the different catechins and theaflavins in biological fluids and tissues.

43 flavin-3'-gallate, theaflavin-3-gallate, and theaflavin inhibited PL with IC50 of 1.9, 4.2, 3.0, and

44 ition of interleukin-8 transcription because theaflavin inhibited tumor necrosis factor-alpha-mediate

45 Theaflavin inhibited tumor necrosis factor-alpha-mediate

46 In addition, theaflavin inhibited tumor necrosis factor-alpha-mediate

47 EGCG and theaflavins inhibited epidermal growth factor- or 12-O-t

48 We conclude that theaflavin is a potent inhibitor of interleukin-8 gene e

49 itory effects on AP-1 activation by EGCG and theaflavins may further explain the anti-tumor promotion

50 the effect of black tea (Camellia sinensis) theaflavins on obesity-related targets.

51 Theaflavin (TF-1), theaflavin-3-monogallate and theaflav

52 nd their epimers, and black tea polyphenols, theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate,

53 ergo oxidative coupling for the formation of theaflavins, theasinensins and polyhydroxylated flavan-3

54 Theaflavin was significantly and positively correlated w

55 ounts of individual catechins, flavonols and theaflavins were determined by HPLC.

56 Higher levels of theaflavins were recorded in orthodox black tea from pur