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1 ey uptake, making it an excellent choice for therapeutic application.
2 typic alterations, with implications for its therapeutic application.
3 between homologous sequences, limiting their therapeutic application.
4 full cardiovascular activities for potential therapeutic application.
5 ptimize HLE culture conditions for potential therapeutic application.
6 ug responses and, thereby, compromises their therapeutic application.
7 ase represent a major safety concern for any therapeutic application.
8  heterogeneous group with high potential for therapeutic application.
9 ce their effects in vivo and could have wide therapeutic application.
10 ich might not be desirable in light of human therapeutic application.
11 iac progenitor cells for widespread clinical therapeutic application.
12 on in wild-type COs, which thus limits their therapeutic application.
13 t and reproducible studies of EV biology and therapeutic application.
14 y of iPSCs is an important consideration for therapeutic application.
15 strong, specific binding for engineering and therapeutic applications.
16 signaling for basic science and possibly for therapeutic applications.
17 ing receptor-specific analogs with potential therapeutic applications.
18 cokinetic properties of oligonucleotides for therapeutic applications.
19  warrant further investigation for potential therapeutic applications.
20 g gene-corrected, patient-specific iPSCs for therapeutic applications.
21 obilized for imaging, biochemical assays, or therapeutic applications.
22 62 immunomodulatory mechanisms with possible therapeutic applications.
23 rnative to wild-type SpCas9 for research and therapeutic applications.
24 ces pave the way toward biotechnological and therapeutic applications.
25 ghting the potential use of this library for therapeutic applications.
26 evising new lecithin delivery strategies for therapeutic applications.
27 tion and the prospects of targeting Bub1 for therapeutic applications.
28 1 receptor, highlighting their potential for therapeutic applications.
29 prognostic biomarker and a target for future therapeutic applications.
30 eukemia cell models to explore its potential therapeutic applications.
31 and may facilitate the development of future therapeutic applications.
32 sicles and their potential in diagnostic and therapeutic applications.
33 ecule delivery to encapsulate stem cells for therapeutic applications.
34  2-fold increased efficacy, suggesting broad therapeutic applications.
35           In addition, miR-126 has potential therapeutic applications.
36 be of value for regenerative medicine and/or therapeutic applications.
37 w a great potential for human diagnostic and therapeutic applications.
38 the use of gold quantum dots for imaging and therapeutic applications.
39 formations suggests advantages for potential therapeutic applications.
40 l biomarkers for diagnostic, prognostic, and therapeutic applications.
41 d specificity of DNA targeting for potential therapeutic applications.
42 potential of nanoparticles in diagnostic and therapeutic applications.
43 nd we discuss its stability and function for therapeutic applications.
44 tro and in vivo, and its inhibition may have therapeutic applications.
45 ting cytokine signaling as well as potential therapeutic applications.
46  development of S6K inhibitors with possible therapeutic applications.
47 of biomolecules for industrial, research and therapeutic applications.
48 development, disease modeling, and potential therapeutic applications.
49 he use of these constructs in diagnostic and therapeutic applications.
50 ghput screening and delivery for in vivo and therapeutic applications.
51  main challenges and prerequisites for their therapeutic applications.
52  reagents would be useful for diagnostic and therapeutic applications.
53 o systems targeted toward HSC generation for therapeutic applications.
54 al modeling for predictive frameworks within therapeutic applications.
55 with wide ramifications for the use of LA in therapeutic applications.
56 s is fundamental to improve their design for therapeutic applications.
57 ional cell types for biomedical research and therapeutic applications.
58  siRNA carriers for in vivo purposes towards therapeutic applications.
59  cells (MSC) have been promoted for multiple therapeutic applications.
60 g potentially harmful genomic integration in therapeutic applications.
61  development and interest for diagnostic and therapeutic applications.
62  decoction or infusion preparations used for therapeutic applications.
63 tential in numerous downstream drug and gene therapeutic applications.
64 ct from infection and reduce viral load upon therapeutic applications.
65  in a broad range of biomedical research and therapeutic applications.
66  this agent for use in future diagnostic and therapeutic applications.
67 nderstanding of myeloma biology and also for therapeutic applications.
68 because it offers numerous possibilities for therapeutic applications.
69 tional studies, for antigen discovery, or in therapeutic applications.
70 pluripotent stem cells under manufacture for therapeutic applications.
71 ase modeling, drug screening, and cell-based therapeutic applications.
72 ds that target alternative binding sites for therapeutic applications.
73 fy aspects of its stability and function for therapeutic applications.
74 xpansion, differentiation, and use in future therapeutic applications.
75 high-quality iPSCs will be needed for future therapeutic applications.
76 tial of these enzymes for basic research and therapeutic applications.
77 ty, which might be of potential interest for therapeutic applications.
78 luable for research and potentially also for therapeutic applications.
79 iation and to solve problems associated with therapeutic applications.
80 er developments of SPI systems to a range of therapeutic applications.
81  clinically relevant rAAV serotypes for gene therapeutic applications.
82  sciences and underlines their potential for therapeutic applications.
83 ists and oncologists can best apply CBCT for therapeutic applications.
84 the balance of globin gene transcription for therapeutic applications.
85  the development of selectin antagonists for therapeutic applications.
86  intercalation has found many diagnostic and therapeutic applications.
87 tegy for improving the SBR in diagnostic and therapeutic applications.
88 y is an important property in industrial and therapeutic applications.
89 dies are critical to understand function and therapeutic applications.
90 ents with potential utility for research and therapeutic applications.
91  relevant noncoding RNA-based diagnostic and therapeutic applications.
92 er elucidating the mechanisms and developing therapeutic applications.
93 bodies highlights their potential for use in therapeutic applications.
94 and can have implications for development of therapeutic applications.
95 is work may provide new insights for CD20-Ab therapeutic applications.
96 acromolecules is a challenge in research and therapeutic applications.
97  agents that induce autophagy may have broad therapeutic applications.
98 optical control and exploration of potential therapeutic applications.
99  the way for antibody tools for research and therapeutic applications.
100 or stem cell research and advancement of its therapeutic applications.
101 e proven useful in gene function studies and therapeutic applications.
102  anti-PTM mAbs for signaling, diagnostic and therapeutic applications.
103 differentiation, cell fate specification and therapeutic applications.
104 s to generate a scalable source of cells for therapeutic applications.
105 ractive biopolymer system for diagnostic and therapeutic applications.
106 h to generate multifunctional antibodies for therapeutic applications.
107 l interest to both life science research and therapeutic applications.
108 s9 system has triggered enormous interest in therapeutic applications.
109 i-inflammatory proteins for potential future therapeutic applications.
110 coholic steatohepatitis, and their potential therapeutic applications.
111 idely studied and developed for cosmetic and therapeutic applications.
112 ogical/pathological processes, and potential therapeutic applications.
113  broadly applicable to numerous research and therapeutic applications.
114 n T cells could potentially be harnessed for therapeutic applications.
115 chemical scaffold for related imaging and/or therapeutic applications.
116 al for a variety of important diagnostic and therapeutic applications.
117 ll biology and engineering of stem cells for therapeutic applications.
118 ntial research applications and, especially, therapeutic applications.
119 ing hypoglycosylated alpha-DG, for potential therapeutic applications.
120 tem has potential use in many diagnostic and therapeutic applications.
121 r communication with possible diagnostic and therapeutic applications.
122 tion of highly specific fully human mAbs for therapeutic applications.
123 xtensively as pesticides and in a variety of therapeutic applications.
124 ing the groundwork for future diagnostic and therapeutic applications.
125 e broad utility in research, diagnostic, and therapeutic applications.
126 ons of PXR that can be explored for relevant therapeutic applications.
127 CE inhibitory potential for nutraceutical or therapeutic applications.
128 otential delivery vectors for diagnostic and therapeutic applications.
129 - or IRAK4-specific inhibitors for potential therapeutic applications.
130 he future to advance biomedical research and therapeutic applications.
131 cific brain circuits for neuroscientific and therapeutic applications.
132 ntiviral vectors (LVs) has several promising therapeutic applications.
133 rea of intense research due to its potential therapeutic applications.
134 d reduce off-target effects for research and therapeutic applications.
135 ng tool and holds immense promise for future therapeutic applications.
136 DNA binding affinity of deaminases for safer therapeutic applications.
137 ications on proteins for many biological and therapeutic applications.
138  new modes of biological activity, including therapeutic applications.
139 otherapy, stem cell reprogramming, and other therapeutic applications.
140 f protein-protein interactions for potential therapeutic applications.
141  be further investigated for their potential therapeutic application against CPE-associated disease.
142 drial metabolic vulnerability with potential therapeutic applications against chemotherapy-resistant
143 ptide in animal models, suggesting potential therapeutic applications against the main pathological t
144 s current SPI-based marketed products, their therapeutic application and associated clinical data.
145 verage energy, 162 keV; Egamma, 159 keV) for therapeutic application and for SPECT imaging.
146 al from Cannabis sativa with a wide range of therapeutic applications and a long history of recreatio
147 e emerged as leading gene delivery tools for therapeutic applications and biomedical research.
148  investigations concerning cancer diagnosis, therapeutic applications, and drug efficacy tests.
149  We also consider the various areas in which therapeutic applications are envisaged: wound healing, a
150                                        Broad therapeutic applications are foreseen for SIRT6 inhibito
151  its mechanistic contributions and potential therapeutic applications are not completely known.
152 e hard to manipulate, focusing translational therapeutic applications at the environments appears to
153 ences research, as well as in diagnostic and therapeutic applications, because of their ability to bi
154 r differences have been suggested in BM-MSCs therapeutic application, but the effect of the androgen
155  antitoxin agents are not only promising for therapeutic applications, but also can be used as tools
156  molecules valued not only for their diverse therapeutic applications, but also for their role in con
157 rative potential is important to develop new therapeutic applications, but the identification advance
158          Reprogramming approaches could find therapeutic applications by inducing beta cell conversio
159 er, transgene expression is not amenable for therapeutic application due to potential insertional mut
160 ious limitations for advanced prosthetic and therapeutic applications due primarily to their lack of
161 al/clinical development for prophylactic and therapeutic applications due to their potency and their
162 , (64)Cu, (44)Sc, (86)Y, (89)Zr), as well as therapeutic applications (e.g.(47)Sc, (114m)In, (177)Lu,
163 ioxidant and anti-inflammatory agent used in therapeutic applications, e.g. in the treatment of diabe
164 r more of three key properties necessary for therapeutic application: efficiency of cleavage at the d
165 ether, these findings provide a platform for therapeutic applications, especially for nervous system
166 underexplored for a majority of nanoparticle therapeutic applications, especially for targeted delive
167 the dystrophin glycoprotein complex may have therapeutic application for all DMD patients, regardless
168              These findings indicate a novel therapeutic application for mTOR inhibitors to disrupt e
169 sing on practical aspects of their potential therapeutic application for selective inhibition of smoo
170  biological processes and in their potential therapeutic application for stress-related psychopatholo
171 hus, videogame training might have important therapeutic applications for amblyopia and other visual
172 resveratrol revealed here suggests potential therapeutic applications for ANCL and possibly other hum
173 ive cancer phenotypes and offer insight into therapeutic applications for better survival of patients
174   Synthetic peptides have been developed for therapeutic applications for decades.
175 ghlighting novel technologies with potential therapeutic applications for diagnosis and treatment.
176  action of DZNep, which may be exploited for therapeutic applications for hematological diseases, inc
177       The results point to several potential therapeutic applications for molecules that selectively
178 ro, and recent studies have demonstrated new therapeutic applications for passively administered bNAb
179  the TERT and MYOCD genes into MSCs may have therapeutic applications for restoring, or rejuvenating,
180 ase gene signatures to display the potential therapeutic applications for these approaches.
181 and the approach to diagnosis, but etiologic therapeutic applications from these advances are now for
182                           In addition to the therapeutic applications, GLP-1 analogs have demonstrate
183 ing a sufficient quantity of CO for possible therapeutic applications has been studied using a cell c
184 umulating biological functions and potential therapeutic applications have drawn interest in the disc
185 as remarkable antitumor activities; however, therapeutic applications have not been possible because
186                             For a successful therapeutic application, however, FimH antagonists shoul
187 ibuted extensively to basic neuroscience and therapeutic applications; however, the dimensional and m
188 ges ahead and further expand the spectrum of therapeutic applications, hybrid lipid-polymer nanocompo
189 acid-sensing ion channels (ASICs) could have therapeutic application in a host of neurological and ps
190  Hsp90 inhibitor and may provide a potential therapeutic application in autoimmune diseases.
191 chanism of action of OSU-T315 with potential therapeutic application in CLL.
192 terial collagenase inhibitors with potential therapeutic application in humans.
193 richuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (
194 for the development of a drug candidate with therapeutic application in mitochondrial oxidative stres
195 r to identify the best donor populations for therapeutic application in muscular dystrophies.
196 rough distinct pathways, providing potential therapeutic application in ocular vascular disease.
197 s been widely documented and their potential therapeutic application in regenerative medicine or angi
198 icate a new role for activation of Epac as a therapeutic application in renal injury associated with
199 8a acts as a tumor suppressor and might have therapeutic application in the treatment of NSCLC.
200  (CLL) cells, which may indicate a potential therapeutic application in this disease
201 t peptide motifs and provide a blueprint for therapeutic applications in a variety of cancers and per
202  safer and better alternative to BM-MSCs for therapeutic applications in cancer patients.
203  and PEA have endogenous roles and potential therapeutic applications in conditions of intestinal hyp
204  valuable pharmacological agent with several therapeutic applications in controlling pain and inflamm
205 protein polymers; furthermore, they may have therapeutic applications in diseases associated with oxi
206 th receptor activation should have important therapeutic applications in diseases such as nonalcoholi
207 nity, and tumor progression and its possible therapeutic applications in human disease.
208 ibitors of BET proteins could have important therapeutic applications in inflammatory renal diseases.
209 n this RDEB model strongly supports proposed therapeutic applications in man.
210 n this RDEB model strongly supports proposed therapeutic applications in man.Journal of Investigative
211 h respect to proof-of-concept cardiovascular therapeutic applications in mouse models-which might eve
212 benign adipose tissue expansion and may have therapeutic applications in obesity or lipodystrophy.
213 diovascular basic science research, possible therapeutic applications in patients with cardiovascular
214  represent a safer alternative for potential therapeutic applications in patients with ischemic myoca
215 integration and provide motivation for novel therapeutic applications in patients with lexical-semant
216                      The use of exosomes for therapeutic applications in stroke is also highlighted.
217 s to explore cellular immunity and potential therapeutic applications in the SIV model.
218 terminate seizures as well as have potential therapeutic applications in treating other neurological
219                        siRNAs have potential therapeutic applications in various dermatological disea
220 ization of acoustic droplet vaporization for therapeutic applications, in particular with respect to
221                                    Potential therapeutic applications include ganglionated plexus abl
222 , skin rejuvenation and hair growth, and for therapeutic applications including influenza vaccination
223  or stromal cells (MSCs) have many potential therapeutic applications including therapies for cancers
224                                 However, for therapeutic applications, intracellular delivery of pept
225      The promise of iPS cell derivatives for therapeutic applications is encouraging albeit very earl
226 d MSCs are widely studied and considered for therapeutic applications, it has remained challenging to
227                                              Therapeutic application of (131)I in RANTES-NIS-MSC-trea
228 port on initial dosimetry data and the first therapeutic application of (131)I-BA52, a novel melanin-
229                Here we report the successful therapeutic application of a complement component, a rec
230 of venous thrombi in vivo, and the potential therapeutic application of a p53 agonist as a treatment
231                                              Therapeutic application of a specific CB2 antagonist als
232 ry human samples could ultimately inform the therapeutic application of an emerging class of chromati
233                                    Moreover, therapeutic application of CNTF reduced body weight in m
234                     Because of the potential therapeutic application of GAG polymers, fragments, and
235 ese findings have important implications for therapeutic application of GHRH agonists to ischemic dis
236 owever, one of the major limitations for the therapeutic application of human MSC (hMSC) is the lengt
237 nd carries major implications for design and therapeutic application of kinase inhibitors.
238                    In addition, the possible therapeutic application of NIR probes to block the patho
239           This study emphasizes the possible therapeutic application of NRF2 inducers in autoimmune d
240  disorders and lay the groundwork for future therapeutic application of optogenetics.
241  has implications for ongoing studies of the therapeutic application of OT in NDD.
242  an explosion of new work with regard to the therapeutic application of proresolving ligands in exper
243             Insulin provides a model for the therapeutic application of protein engineering.
244 taste aversion may open the possibility of a therapeutic application of PYY for the treatment of obes
245                            The potential for therapeutic application of splice-switching oligonucleot
246                 Next, we tested the possible therapeutic application of the Fcmu-drug conjugate in im
247 sensory functions that could be rescued with therapeutic application of the heat shock protein in viv
248 toxicity, paving the way for prophylactic or therapeutic application of the peptide in vivo.
249 tors or inhibitors and discuss the potential therapeutic application of their ligands.
250               We also evaluate the potential therapeutic application of these compounds in different
251                               To explore the therapeutic application of these protocols, we studied t
252 croRNAs and represent a step toward possible therapeutic application of this reprogramming approach.
253  between patients, which will be crucial for therapeutic application of this technology.
254 psychiatric and neurodegenerative disorders, therapeutic application of VEGFD may help to stabilize d
255             These results showcase potential therapeutic applications of 17e in both vaccine adjuvant
256  desirable in basic stem cell technology and therapeutic applications of cells.
257                                     However, therapeutic applications of Delta(9)-tetrahydrocannabino
258 orted populations, underlining the potential therapeutic applications of GP2.Pancreatic progenitors (
259 hylactic reaction would also limit potential therapeutic applications of IV.3.
260 eep disorders, and depression, new potential therapeutic applications of melatonergic ligands includi
261 iscussed are the potential bioanalytical and therapeutic applications of mismatch-binding ligands.
262                 Finally, we examine possible therapeutic applications of Na(v) ligands and provide an
263 ew could have important implications for the therapeutic applications of oxytocin in conditions chara
264                                              Therapeutic applications of peptides are currently limit
265 ellum of the AS mouse model and on potential therapeutic applications of rapamycin.
266                                       Recent therapeutic applications of recombinant APC in ischemic
267 hat caution should be exercised in potential therapeutic applications of resveratrol in human inflamm
268 elerate a wide array of biotechnological and therapeutic applications of the CRISPR-Cas technology.
269                                The potential therapeutic applications of these analogues are limited
270 ever, the study of iNKT cell biology and the therapeutic applications of these cells are greatly limi
271                                        Human therapeutic applications of these technologies will ulti
272 xploited as carriers for in vivo imaging and therapeutic applications, owing to their capability to e
273 roy target proteins for biotechnological and therapeutic applications.Proteases are promising therape
274                           Consequently, each therapeutic application requires different settings: non
275 ials for diverse analytical, biomedical, and therapeutic applications requires determination of surfa
276 ntial markers and targets for diagnostic and therapeutic applications, respectively.
277 ic nanoparticles are promising new tools for therapeutic applications, such as magnetic nanoparticle
278 vo cardiac function of IF1 and the potential therapeutic application targeting IF1 remain obscure.
279 delivery, and explore the array of potential therapeutic applications that have been reported.
280 9) limits its utility for basic research and therapeutic applications that use the highly versatile a
281 ly broad translatability of our strategy for therapeutic applications.The therapeutic use of single-c
282 lthough Pep2-8 itself may not be amenable to therapeutic applications, this study demonstrates the fe
283 ilitate exciting new avenues of research and therapeutic applications through AAV-based delivery of C
284 ion in claudin-low tumors offers a potential therapeutic application to disrupt the EMT program on mu
285 ntly under investigation for their potential therapeutic application to Down syndrome and Alzheimer's
286 mis-splicing and provide a framework for its therapeutic application to neurodegenerative conditions
287 tive disorders, but also seem to have unique therapeutic applications to directly target and remodel
288              Although there are many current therapeutic applications to manipulate IFN-I pathways, w
289 opriate hydrolytic stability to expand their therapeutic applications towards more advanced areas.
290                               With regard to therapeutic applications, two undesired features of this
291  of new molecular targets for diagnostic and therapeutic applications using in vitro methods is an im
292 onal networks, thereby setting the stage for therapeutic applications using this platform.
293 s, representing a new alternative for future therapeutic applications via this route.
294 f this gated nanozyme for use in imaging and therapeutic applications was demonstrated through trigge
295                                       Toward therapeutic applications, we also show that CD4-LV can b
296 uction of pluripotent stem cells (iPSCs) for therapeutic applications will require practical methods
297 m will enable new industrial, diagnostic and therapeutic applications with engineered cells.
298  it ideal for a wide range of diagnostic and therapeutic applications with great promise for potentia
299 izure-induced astrocyte injury and potential therapeutic applications with mTOR inhibitors.
300 e mature stem cell-derived somatic cells for therapeutic applications without the requirement of gene

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