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1 for additional office visits to confirm the therapeutic effect.
2 activity-dependent protein synthesis in the therapeutic effect.
3 and TNFR2 signaling, however, abrogated the therapeutic effect.
4 th lymphocyte responses required by IFNalpha therapeutic effect.
5 a by these cells is crucial for the observed therapeutic effect.
6 eving a comfortable and improved acupuncture therapeutic effect.
7 fect, adjusted IOP-lowering effect, and true therapeutic effect.
8 roenterologist and radiologist assessing the therapeutic effect.
9 rder to potentially modulate the process for therapeutic effect.
10 ociated downstream toxicity, demonstrating a therapeutic effect.
11 he size of established tumors and exhibits a therapeutic effect.
12 ral linear mixed models were used to examine therapeutic effect.
13 ch as the price tag, can strongly affect its therapeutic effect.
14 ulate when, where, and how a drug exerts its therapeutic effect.
15 relate of disease severity, progression, and therapeutic effect.
16 -soluble contrast) influences this potential therapeutic effect.
17 ung with sufficient efficacy for a sustained therapeutic effect.
18 es, the nanovaccine demonstrates substantial therapeutic effect.
19 fficacious, tumor-specific, and long-lasting therapeutic effect.
20 ed immune reactions that interfered with the therapeutic effects.
21 agonist immunotherapy resulting in synergic therapeutic effects.
22 ogeneity of exosomes on their biological and therapeutic effects.
23 tional properties of the siRNAs for combined therapeutic effects.
24 the catalyst environment and afford distinct therapeutic effects.
25 itumor lymphocytes, possibly weakening their therapeutic effects.
26 o ketamine or as possible transducers of its therapeutic effects.
27 mechanisms of action to enhance synergistic therapeutic effects.
28 er their poor brain uptake might limit their therapeutic effects.
29 a potential novel mechanism contributing to therapeutic effects.
30 notypes, cellular addressing and duration of therapeutic effects.
31 common neurobiological process mediating the therapeutic effects.
32 e biomarkers for target engagement and early therapeutic effects.
33 and superior photostability with activatable therapeutic effects.
34 CD44 receptors, which were essential for the therapeutic effects.
35 fy them with LEC markers, and evaluate their therapeutic effects.
36 -induced changes in neuronal activity to its therapeutic effects.
37 CDDP and pyridoxine exhibited hyperadditive therapeutic effects.
38 that they interact with to precipitate their therapeutic effects.
39 tinal scavenger, which may contribute to its therapeutic effects.
40 diseases where GSK-3beta inhibition exhibits therapeutic effects.
41 e to ketamine or have a role in its possible therapeutic effects.
42 ent co-regulators to produce tissue-specific therapeutic effects.
43 ng how anti-CTLA4 immunotherapy mediates its therapeutic effects.
44 targeting these cells can elicit potentially therapeutic effects.
45 enchymal stem cell (MSC) studies assume that therapeutic effects accrue from local myocardial effects
47 embered ring (11-cis-6mr)-retinal, which has therapeutic effects against certain degenerative retinal
48 IFNAR1 by UV as a major mechanism of the UV therapeutic effects against the psoriatic inflammation a
50 effects of opioids that underlie both their therapeutic effects (analgesia) and their adverse effect
51 repeated measurement was used to examine the therapeutic effect and changes in BDNF and cytokine leve
52 d clarify the underlying mechanisms of their therapeutic effect and define the appropriate conditions
53 BCM-PTX injection further improved the tumor therapeutic effect and elongated the survival time of th
54 nalog of NSC-370284, exhibited a more potent therapeutic effect and prolonged the median survival of
56 cal HIFU system revealed correlation between therapeutic effect and thermal parameters, which was abs
58 Theranostics, systems that have combined therapeutic effects and diagnostic capabilities, have ga
60 diated killing is essential for the observed therapeutic effects and that natural killer cells consti
61 ce the toxicity and side effect, improve the therapeutic effect, and exhibit great potential in clini
62 xhibits enhanced stability, more significant therapeutic effects, and a more than 10-fold improvement
69 ring effect was almost identical to the true therapeutic effect at each of the 3 time points (0.43 [3
71 Combined RAF and EGFR inhibition exerts a therapeutic effect, but resistance invariably develops t
72 Also, these findings showed that CR has a therapeutic effect by attenuating the deleterious effect
73 e the desired specificity and a long-lasting therapeutic effect by inducing myelin-specific regulator
74 d IOP-lowering effect overestimated the true therapeutic effect by mean (SD) 2.5 (4.8), 3.1 (3.8), an
75 r data suggest that anti-CD48 mAb exerts its therapeutic effects by both limiting CD4(+) T cell proli
77 method monitored mAb-IR700 distribution and therapeutic effects during PIT at different intratumor l
79 rug-protein interactions contribute to their therapeutic effect (even when DNA is the dominant target
82 l for understanding a variety of natural and therapeutic effects for example in bone tissue healing a
84 consistent with the idea that its potential therapeutic effects for treating posttraumatic stress di
85 These findings suggest that aSWNTs may have therapeutic effects for treatment of METH addiction by o
86 tantly, the in vitro and in vivo anti-cancer therapeutic effects have been shown efficacious, implyin
87 preclinical studies of lung injury, but its therapeutic effects have never been investigated in acut
88 reactive oxygen species (ROS) diminishes the therapeutic effect in a hypoxic environment, such as sol
89 on by Tregs is a fundamental aspect of their therapeutic effect in autoimmunity and transplantation.
90 Thus, targeting CTSK would have a potential therapeutic effect in both the bone system and the immun
91 3K/AKT/mTOR signaling can have a synergistic therapeutic effect in cells from a subgroup of CLL patie
92 g for idiopathic pulmonary fibrosis, for its therapeutic effect in cGVHD mouse models with distinct p
93 could potentially be exploited to achieve a therapeutic effect in other HIV-seropositive individuals
94 thought to contribute to how ECP exerts its therapeutic effect in patients with chronic graft-versus
95 cycle in the brain, we wished to assess its therapeutic effect in patients with glucose transporter
96 rigger mTNF-alpha, might contribute to their therapeutic effect in the treatment of certain inflammat
99 naeus ensis (Met e 1), and to evaluate their therapeutic effects in a Balb/c mouse model of Met e 1 h
100 educes lysosomal lipid accumulations and has therapeutic effects in animal models of Niemann-Pick dis
101 ly, JNK inhibitors exerted potent antifungal therapeutic effects in both mouse and human cells infect
105 amounts of IL-10, Tr1 cells may have unique therapeutic effects in disease-associated inflammasome a
106 chanisms and targets through which GCs exert therapeutic effects in diseases such as asthma remain in
107 e findings suggest that BET inhibitors exert therapeutic effects in leukemia by evicting BRD4-NSD3-CH
109 ges its intended targets and exerts profound therapeutic effects in models of intestinal inflammation
111 central nervous system (CNS) and explore its therapeutic effects in our SBMA mouse model that harbors
112 r (HDACi) treatment, potentially linking the therapeutic effects in P23H rhodopsin animals and negati
113 adverse effect profile, this agent's overall therapeutic effects in patients with Alzheimer's disease
114 ecfidera; Biogen, Cambridge, MA), have shown therapeutic effects in several disease models, prompting
115 phocytes (CAR-T cells) has had less striking therapeutic effects in solid tumors than in lymphoid mal
119 tor, show comparable alpha-syn clearance and therapeutic effects in the PD mouse model, the latter ad
121 logic analysis was used to demonstrate local therapeutic effects in treated brain tumor sections.
122 netic or pharmacological MGL ablation exerts therapeutic effects in various preclinical disease model
123 and PSMA-IgG-IR700 conjugate showed similar therapeutic effects in vitro and in vivo on PSMA-positiv
128 acute ischemic stroke patients and that the therapeutic effect may be based on the modulation of XXM
130 hronic and blast phase CML cells resulted in therapeutic effects mediated by murine effector cells.
131 im of this study was to directly compare the therapeutic effect of (177)Lu-DOTA-octreotate, an SSTR a
136 ession PD model, we demonstrate a beneficial therapeutic effect of AZD1480, a specific inhibitor of J
137 IIIA/CD16, contributing significantly to the therapeutic effect of CD20 monoclonal antibodies (mAb).
141 This study sought to determine whether the therapeutic effect of culture-expanded MSCs persists, ev
144 drugs used in 78 diseases indicates that the therapeutic effect of drugs is localized in a small netw
145 interactome, proximity helps us uncover the therapeutic effect of drugs, as well as to distinguish p
147 ecovery of retinal laser injury, whereas the therapeutic effect of exosomes was abolished when MSC-Ex
148 roinjecting anisomycin into mPFC blocked the therapeutic effect of extinction on cognitive flexibilit
152 cular endothelial growth factor enhances the therapeutic effect of human amniotic fluid stem cells in
154 del that can be used to evaluate in vivo the therapeutic effect of increasing IKAP levels by correcti
155 The present study aimed to investigate the therapeutic effect of injections of local bone marrow me
157 g agent (111)In-3BP-227, we investigated the therapeutic effect of its (177)Lu-labeled analog on the
159 me these limitations and further improve the therapeutic effect of LMWH, we designed a novel combinat
160 Recent clinical evidence suggests that the therapeutic effect of massage involves the immune system
161 er, Leitzinger, and colleagues delineate the therapeutic effect of methanobactin (MB), a potent bacte
167 urther investigated the relation between the therapeutic effect of pHIFU and thermal parameters in bu
168 e concept that targeted HNPs can enhance the therapeutic effect of photothermal ablation, which prese
169 tralization of IL-27 completely reversed the therapeutic effect of R848 in the experimental asthma mo
170 e (RELAX) trial, physiological variables and therapeutic effect of sildenafil were examined relative
173 e of Cox-2 in the mechanisms of NIHL and the therapeutic effect of the Cox-2 inhibitor NS398 on NIHL
181 Our data provide further evidence for a therapeutic effect of TSO in IBD, yet caution is require
182 CdR, and provided valuable insights into the therapeutic effects of 5-Aza-CdR in current clinical tri
184 of acupuncture needles further enhances the therapeutic effects of acupuncture treatment in CRC rats
190 his study uncovers mechanisms underlying the therapeutic effects of BETi in melanoma and reveals the
191 offered a strong support for the beneficial therapeutic effects of bis(heptyl)-cognitin in the treat
192 ed efficacy.Humans are less sensitive to the therapeutic effects of botulinum neurotoxin B (BoNT/B) t
194 d by an antagonist of GPR55, suggesting that therapeutic effects of CBD are mediated through this lip
195 etent mouse tumor models, we reveal that the therapeutic effects of CD47 blockade depend on dendritic
198 accumulation in the CNS and to evaluate the therapeutic effects of compounds targeting alpha-syn.
199 f this study is to investigate the potential therapeutic effects of cortistatin in two well-establish
205 e contribution of GLP-1 as a mediator of the therapeutic effects of dipeptidyl peptidase 4 (DPP-4) in
207 cell function and has been implicated in the therapeutic effects of drugs used to treat epilepsy and
211 is responsible, at least partially, for the therapeutic effects of fenofibrate on diabetic nephropat
212 n adult mice treated with FGF2 precluded the therapeutic effects of FGF2 on anxiety behavior, suggest
213 gene regulatory pathway that contributes to therapeutic effects of GCs in DMD through proergogenic m
214 fection progression due to Coc ingestion and therapeutic effects of highly specific drugs are measura
216 IONALE: Paracrine secretions seem to mediate therapeutic effects of human CD34(+) stem cells locally
217 imal models have demonstrated the beneficial therapeutic effects of infections by parasitic worms (he
224 to develop the concept that the multifaceted therapeutic effects of low-dose aspirin may reflect plei
225 reduced mortality, probably by extending the therapeutic effects of lung protective ventilation.
228 dy was designed to assess the preventive and therapeutic effects of NRG4 overexpression on high fat d
231 ify candidate factors that contribute to the therapeutic effects of porcine MSC-derived EVs, we chara
233 tion in patients with PAH, and the potential therapeutic effects of pyridostigmine (PYR), an oral dru
234 immune-suppressive phenotype that limits the therapeutic effects of radiation on invasive PDAs and ac
235 xamination of angiotensin peptide levels and therapeutic effects of recombinant human ACE2 (rhACE2) o
237 nd investigate the in vivo antimicrobial and therapeutic effects of TA-nHP66 biomaterials and their i
239 ological activity, the structural basis, and therapeutic effects of the family of multitargeted compo
242 ment of neurological disorders; however, the therapeutic effects of these cells on CNS neurons are no
243 o determine the key ingredient mediating the therapeutic effects of YQHX and to examine its effect on
244 growth factor receptor 2 yielded an additive therapeutic effect on both area and number of spontaneou
246 ergy; however, its safety, tolerability, and therapeutic effect on cardiac structure and function hav
248 thy tissues during radiation and the minimal therapeutic effect on the organ-of-interest (target) is
252 from certain medications without recognized therapeutic effects on Borrelia burgdorgeri to stem cell
254 Moreover, IL-3 showed the preventive and therapeutic effects on cartilage degeneration induced by
255 nia with particular emphasis on its putative therapeutic effects on each of the three above-mentioned
256 alpha-specific inhibitor, had preventive and therapeutic effects on metabolic disorders that were dep
257 positive symptoms but typically have minimal therapeutic effects on negative symptoms and cognitive d
258 wer intraocular pressure (IOP); however, its therapeutic effects on outflow physiology are location-
259 nd did not result in weight-loss-independent therapeutic effects on postprandial glycemic control.
260 novel mechanism by which ketamine exerts its therapeutic effects on stress-induced cognitive dysfunct
261 of small diameter afferent nerve fibres and therapeutic effects on the associated visceral organs, w
264 significantly improved pharmacokinetics and therapeutic effects over the native protein/peptide upon
265 f continuous treatment is required to elicit therapeutic effects, prolonging the period of depression
269 chemia in diabetic patients yielded a modest therapeutic effect resulting from cell dysfunction.
270 e, a broad treatment window and long-lasting therapeutic effects should make the RP2 gene therapy att
271 mGlu5 NAM activity is sufficient to produce therapeutic effects similar to full mGlu5 NAMs, but with
272 ent of inflammatory diseases would produce a therapeutic effect superior to global inhibition of pros
274 preparations show antidepressant activity, a therapeutic effect that has been linked to hippocampal n
275 warrant further investigation to examine the therapeutic effects that STN HFS may have on relapse in
276 ty of HU may significantly contribute to its therapeutic effects, the underlying mechanisms remain po
277 t low doses of mGluR2/3 stimulation may have therapeutic effects through unexpected postsynaptic acti
278 eting specificity, thus resulting in limited therapeutic effects toward the tumor but severe drug-ind
279 rferons and nucleotide analogs, have limited therapeutic effects, underscoring the need to identify e
280 f relapsing multiple sclerosis and may exert therapeutic effects via activation of the nuclear factor
281 se results suggest a novel mechanism for PDM therapeutic effects via initial PDM DAT inhibition follo
282 unadjusted effect of treatment and the true therapeutic effect was 0.55 (95% CI, 0.23-0.76), and the
284 ental periodontitis was induced in vivo, and therapeutic effect was evaluated with microcomputed tomo
288 r the Fc domain of HJ8.5 is required for the therapeutic effect, we engineered single-chain variable
289 ween chondrocytes and nanocapsules and their therapeutic effect, we pursued a complementary analytica
294 irement for an additional visit to check the therapeutic effect when commencing therapy in the second
295 europhysiology in post-stroke dysphagia with therapeutic effects which are critically dependent on th
297 arget enables the possibility of an enhanced therapeutic effect with reduced off-target toxic side ef
299 ic profiling of pre-existing drugs for novel therapeutic effects with often intractable pathological
300 the ability to introduce specific beneficial therapeutic effects without disrupting the integrity of
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