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1 ggest that these pathways can be studied for therapeutic intervention.
2 ffect, representing an attractive target for therapeutic intervention.
3 lective options for diagnosis as well as for therapeutic intervention.
4 ms of growth and metastasis, and response to therapeutic intervention.
5 indicating potentially viable strategies for therapeutic intervention.
6 egions in cancer, and expose new targets for therapeutic intervention.
7 rovide novel targets for IMiD resistance and therapeutic intervention.
8 integration and offer a potential target for therapeutic intervention.
9 gene pair makes it an attractive target for therapeutic intervention.
10 se, and is considered a potential target for therapeutic intervention.
11 nthetic lethality-based options for targeted therapeutic intervention.
12 ance, specificity, duration, and response to therapeutic intervention.
13 y components of this pathway are targets for therapeutic intervention.
14 - and/or process-specific, and responsive to therapeutic intervention.
15 GB1-deficient patients and a wide window for therapeutic intervention.
16 as therefore been an attractive strategy for therapeutic intervention.
17 ion, US28 may provide a potential target for therapeutic intervention.
18 ity to accurately identify patients who need therapeutic intervention.
19 ches, and could supply new opportunities for therapeutic intervention.
20 is, thus, expected to provide new ground for therapeutic intervention.
21 s, which presents enormous opportunities for therapeutic intervention.
22 ification appear to be targets for potential therapeutic intervention.
23 cer immunotherapy has emerged as a promising therapeutic intervention.
24 tion and that this role can be exploited for therapeutic intervention.
25 these interactions may represent targets for therapeutic intervention.
26 pulation and the stage of development of the therapeutic intervention.
27 rogating miRNA gene function and miRNA-based therapeutic intervention.
28 ble observation has not been translated into therapeutic intervention.
29 ease progression, and identify new nodes for therapeutic intervention.
30 after HCT and as an important new target for therapeutic intervention.
31 largely driven by cancer cells that survive therapeutic intervention.
32 amilial cases, and suggest novel targets for therapeutic intervention.
33 s of poor outcomes and potential targets for therapeutic intervention.
34 S, thereby identifying potential targets for therapeutic intervention.
35 into pathogenesis and potential targets for therapeutic intervention.
36 optimization of these types of compounds for therapeutic intervention.
37 ICP changes is no longer apparent because of therapeutic intervention.
38 vealing astrocytes as a potential target for therapeutic intervention.
39 PK/ERK pathways may be promising targets for therapeutic intervention.
40 ts with LS/OS, including a model for testing therapeutic intervention.
41 ut bacterial communities may be a target for therapeutic intervention.
42 ellular aggregation as potential targets for therapeutic intervention.
43 zures naturally remits over time without any therapeutic intervention.
44 hypertension and may point to novel areas of therapeutic intervention.
45 ified a novel target that can be pursued for therapeutic intervention.
46 and neurodegeneration and to new targets for therapeutic intervention.
47 ling cascades could provide new pathways for therapeutic intervention.
48 life, thus providing a potential window for therapeutic intervention.
49 des by identifying key strategies for future therapeutic intervention.
50 ompting the need to identify new targets for therapeutic intervention.
51 determination of a suitable time window for therapeutic intervention.
52 from toxicity, providing a novel target for therapeutic intervention.
53 ons for inflammation-associated diseases and therapeutic intervention.
54 phenotypes may identify patients amenable to therapeutic intervention.
55 e prevention, pathogenesis, progression, and therapeutic intervention.
56 at may serve as a novel target for antiviral therapeutic intervention.
57 t of lethal PCa and nominate new avenues for therapeutic intervention.
58 ormation-driven synthetic lethal targets for therapeutic intervention.
59 as identified potential options for targeted therapeutic intervention.
60 ur results suggest several novel targets for therapeutic intervention.
61 ith potential implications for prognosis and therapeutic intervention.
62 g pathogenesis, and often requires high-risk therapeutic intervention.
63 tch offers a potential target for 22q11.2 DS therapeutic intervention.
64 nfection and are attractive focus points for therapeutic intervention.
65 uman disorders and is a promising target for therapeutic intervention.
66 with NAFLD and identification of targets for therapeutic intervention.
67 ing axis represents an attractive target for therapeutic intervention.
68 dentifies novel windows of preventive and/or therapeutic interventions.
69 uld be important in disease pathogenesis and therapeutic interventions.
70 hts and may potentially guide development of therapeutic interventions.
71 D at or beyond 6 hours and may trigger early therapeutic interventions.
72 -two important considerations for envisioned therapeutic interventions.
73 rone tau, and as such, a possible target for therapeutic interventions.
74 ctures fail to heal and for developing novel therapeutic interventions.
75 studies thus provide a framework for future therapeutic interventions.
76 rate penumbra tissue, which can benefit from therapeutic interventions.
77 e pathogenesis and as an outcome measure for therapeutic interventions.
78 provide unique insight to exploit for novel therapeutic interventions.
79 ors may allow for implementation of targeted therapeutic interventions.
80 esents many potential sites for targeting in therapeutic interventions.
81 characterized, impending the development of therapeutic interventions.
82 nical follow-up documenting improvement with therapeutic interventions.
83 into RTT etiology that support personalized therapeutic interventions.
84 ynamics could be a pharmacological target in therapeutic interventions.
85 se mechanisms with differential responses to therapeutic interventions.
86 ell as assess potential new prophylactic and therapeutic interventions.
87 ed viral suppression after withdrawal of all therapeutic interventions.
88 s who might benefit from early diagnosis and therapeutic interventions.
89 -fetal transmission is needed to develop new therapeutic interventions.
90 o be novel candidates for the development of therapeutic interventions.
91 any life-threatening diseases and optimizing therapeutic interventions.
92 omplications and the target of most existing therapeutic interventions.
93 come host defenses and to maximize potential therapeutic interventions.
94 cted to help in the design of anti-infective therapeutic interventions.
95 ical trials and the development of effective therapeutic interventions.
96 te causal pathologic sequences and potential therapeutic interventions.
97 ls to further studies of etiopathologies and therapeutic interventions.
98 eneity has remained an untapped resource for therapeutic interventions.
99 hting mitochondria as a potential target for therapeutic interventions.
100 emic will require effective prophylactic and therapeutic interventions.
101 ts and successfully abolish them by targeted therapeutic interventions.
102 insights applicable to future diagnostic and therapeutic interventions.
103 or the identification and development of new therapeutic interventions.
104 , highly resistant pathogens requiring novel therapeutic interventions.
105 s a multitude of pathological conditions and therapeutic interventions.
106 uR2/3 mechanisms in primates will help guide therapeutic interventions.
107 ts towards interesting new possibilities for therapeutic interventions.
108 s cell carcinomas (HNSCCs) are refractory to therapeutic interventions.
109 and thus, may serve as targets for potential therapeutic interventions.
110 drug resistance may reveal opportunities for therapeutic interventions.
111 ut their pathogenic mechanisms and potential therapeutic interventions.
112 different infections and requiring different therapeutic interventions.
113 nd offer potentially untapped mechanisms for therapeutic interventions.
114 ved is critical for identifying or improving therapeutic interventions.
115 of their functions is currently the focus of therapeutic interventions.
116 orm about disease mechanisms and lead to new therapeutic interventions.
117 d in developing physical and pharmacological therapeutic interventions.
118 preventive vaccines, as well as immune-based therapeutic interventions.
119 he absence of rebleeding, blood transfusion, therapeutic intervention, 28 day readmission, or death.
120 focus on whether TRIM6 could be targeted for therapeutic intervention against EBOV infection.IMPORTAN
121 ediated translation strategy is a target for therapeutic intervention against this viral disease.
122 cephalitis virus, opening up new avenues for therapeutic interventions against neurotropic flavivirus
123 generation and this offers opportunities for therapeutic intervention aimed at the prevention of neur
125 ance, and may be a key point to consider for therapeutic interventions aimed at restoring network fun
126 ribes the biological phenotypes of HFpEF and therapeutic interventions aimed at targeting these pheno
127 tions holds great promise for devising novel therapeutic interventions, although it faces challenges
129 rent disease stages may open new avenues for therapeutic intervention and modification of inflammator
130 development of metastases, recurrence after therapeutic intervention and reduced overall survival.
131 ed levels of clotting factor, after a single therapeutic intervention and without the need for furthe
133 ood to identify targets for prophylactic and therapeutic interventions and develop alternative CNS-di
135 st entry may contribute to optimize targeted therapeutic interventions and help prioritize high-risk
136 n will enable the development of appropriate therapeutic interventions and mitigation strategies for
137 ession, and provide avenues for personalized therapeutic interventions and precision medicine for opt
139 model of sporadic GIST model was amenable to therapeutic intervention, and it recapitulated clinical
140 lination, making them a potential target for therapeutic intervention, and that phosphorylation of CR
141 des a potential underlying neural target for therapeutic interventions, and for identifying those at
143 ore these recently-identified mechanisms and therapeutic interventions are being tested, which hopefu
147 disease (AD) and are considered targets for therapeutic intervention as well as biomarkers for diagn
148 n immune cell function, disease etiology and therapeutic intervention, as well as broader principles
149 ant model is important for testing potential therapeutic interventions before human clinical trials.
150 me diversification, and identify targets for therapeutic intervention by disrupting an essential RNA-
152 received an extinction learning session as a therapeutic intervention by repeated exposure to the ton
153 ain processing of drug-associated cues where therapeutic interventions could be effective in treating
155 wever, preclinical trials aimed at improving therapeutic interventions do not take advantage of real-
156 s is key to uncovering new opportunities for therapeutic intervention during early metastatic dissemi
157 ce and represents a new potential avenue for therapeutic intervention during the transition period.
158 ErbB4/EGFR as a novel, druggable target for therapeutic intervention, especially because several pan
159 tory-inhibitory balance could be a promising therapeutic intervention for aggression arising in certa
160 only class of antiviral drugs available for therapeutic intervention for AIV-infected patients, stud
164 cells, which make miR-30a a novel target of therapeutic intervention for human diabetic cataract.
165 ion of these proteins has emerged as a novel therapeutic intervention for IBD although its effect on
166 tion that targeting HuR might be a potential therapeutic intervention for managing autoimmune disorde
167 e eosinophils and offer new entry points for therapeutic intervention for obesity and its complicatio
168 suggest that CSE inhibition may be a useful therapeutic intervention for preventing CB-driven sleep
169 ammatory disease diagnosis and the effect of therapeutic intervention for RA on periodontal disease.
170 BA, an FDA-approved drug, has potential as a therapeutic intervention for RyR1 myopathies that are as
171 ay therefore serve as a potential target for therapeutic intervention for stress-related pathology.SI
173 ause of ataxia is essential due to potential therapeutic interventions for immune and some genetic at
174 ave important implications for the design of therapeutic interventions for MS at different stages of
178 will help to better develop and design novel therapeutic interventions for the treatment of HIV-assoc
179 ablishing their potential use as targets for therapeutic intervention has been limited by the lack of
180 ive pressures including genetic alterations, therapeutic interventions, heterocellular components and
181 nds are required for a plethora of GPCRs for therapeutic intervention, however GPCR X-ray structures
182 scuss preclinical studies targeting Fyn as a therapeutic intervention in AD and our recent experience
183 ling events is highly relevant to successful therapeutic intervention in advanced human prostate canc
187 of B cell homeostasis, and it is a target of therapeutic intervention in autoimmune diseases and lymp
188 le offering potent new tools for approaching therapeutic intervention in autoimmunity and inflammator
189 l mechanism could open new possibilities for therapeutic intervention in cardiovascular diseases.
190 ust CD8(+) T cell responses is necessary for therapeutic intervention in chronic infectious diseases
191 vbeta1 integrin could thus hold promise as a therapeutic intervention in CKD characterized by renal f
192 ons, thereby laying the foundation for a new therapeutic intervention in corresponding human patients
194 ith CypD provides a promising new target for therapeutic intervention in diabetic encephalopathy.
195 ht into disease pathogenesis, diagnosis, and therapeutic intervention in difficult-to-treat subjects.
198 d ERG activation that could be exploited for therapeutic intervention in ERG-positive prostate cancer
199 ng and targeting sleep as a standard part of therapeutic intervention in individuals with autism.
200 to the UPR(ER) will provide new avenues for therapeutic intervention in metabolic disease, neurodege
202 ht the complexity of targeting microglia for therapeutic intervention in neurodegenerative diseases.
206 suggest that squalamine could be a means of therapeutic intervention in Parkinson's disease and rela
207 tor H a promising pharmaceutical product for therapeutic intervention in patients suffering from comp
208 line be considered in the decision for early therapeutic intervention in patients with primary membra
209 with ruxolitinib is an important option for therapeutic intervention in patients with STAT1 GOF muta
211 They are of broad interest as a site for therapeutic intervention in serious mental illness, yet
212 ansformation, highlighting opportunities for therapeutic intervention in specific myeloid and lymphoi
213 ults highlight EZH2 as a rational target for therapeutic intervention in sunitinib-resistant ccRCC as
215 rception of space has been guiding effective therapeutic interventions in a number of unilateral chro
216 e will allow mechanism-based design of novel therapeutic interventions in AD and promises coherent im
217 te that SIRT2 will be a potential target for therapeutic interventions in aging- and stress-induced c
221 ame aversive outcome, precisely the goals of therapeutic interventions in human anxiety disorders.
222 hese consequences are the precisely goals of therapeutic interventions in human anxiety disorders.
223 rotein synthesis supports their potential as therapeutic interventions in human diseases associated w
225 ath pathways will help in the development of therapeutic interventions in intestinal pathologies.
226 providing the platform for potential future therapeutic interventions in neuro-inflammatory patholog
227 21(low) B cells may provide a new option for therapeutic interventions in patients with expanded CD21
229 anolol may be a useful adjunct to behavioral therapeutic interventions in recently traumatized indivi
230 eraction might provide some novel target for therapeutic interventions in the course of pathological
232 nt neuronal plasticity is crucial to finding therapeutic interventions in the myriad of disorders whe
233 tasis and provides a rationale for potential therapeutic interventions in the treatment of breast can
234 ggest promising molecular targets for future therapeutic interventions in these devastating disorders
237 an attractive target for the development of therapeutic interventions, including drugs and vaccines
238 ty promotes positive energy balance, and the therapeutic intervention inhibiting JNK activities repre
239 types, pointing to a cellular mechanism for therapeutic intervention into aging-related neuronal dis
240 s suggest the suitability of this vector for therapeutic intervention into diseases of the central ne
242 a wide range of traumatic injuries for which therapeutic intervention is not immediately feasible.
244 emain high, and there are few evidence-based therapeutic interventions known to clearly improve patie
246 scovery strategy with the potential to offer therapeutic interventions not achievable with existing a
248 f anaphylaxis and identify a new pathway for therapeutic intervention of IgE-mediated reactions.
249 tory cycle by hCG opens new perspectives for therapeutic intervention of inflammatory liver diseases.
251 ght the current and future opportunities for therapeutic intervention of mast cell functions in infla
255 activity will facilitate early diagnosis and therapeutic intervention of this novel disorder.The NRF2
257 homeostasis and, thus, are prime targets for therapeutic interventions of diseases such as cancer and
258 als describing pathophysiology, genetics, or therapeutic interventions relevant to specific cardiovas
260 an disease, where targeting demyelination by therapeutic interventions remains a major open challenge
262 pite advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections c
266 nner provides a basis for tACS as a putative therapeutic intervention.SIGNIFICANCE STATEMENT Gamma os
267 These measures could be used to evaluate therapeutic intervention strategies in animal models of
268 specific components of the EMT pathways as a therapeutic intervention strategy to prevent chlamydia-r
272 allowed for the development of more precise therapeutic interventions targeting the most relevant mo
273 utcomes, but there is a paucity of effective therapeutic interventions targeting these deficits.
274 ddressed by a constantly growing armament of therapeutic interventions targeting tumor-supportive imm
275 is then utilized to simulate anti-angiogenic therapeutic interventions targeting VEGFR2-ERK1/2 axis.
276 ally more treatment refractory to subsequent therapeutic interventions than previously untreated pati
277 These findings may provide the basis for therapeutic interventions that affect IL-22 production b
278 ensitization and oral food immunotherapy are therapeutic interventions that allow individuals who rea
279 pathways of immune activation and also that therapeutic interventions that reduce viral disease acti
280 This result is encouraging for designing new therapeutic interventions that remediate falls risk.
281 gy and cancer may point to novel avenues for therapeutic interventions that stand to benefit both dis
282 l dysfunction and IG release may be a viable therapeutic intervention to help reduce the incidence of
284 uring CA-MRSA infection may serve as a novel therapeutic intervention to limit the associated tissue
285 s and failure, and suggest a potential early therapeutic intervention to mitigate progression of isch
287 pathway mediators could thus be developed as therapeutic interventions to alleviate or prevent neuroi
288 s tractable for investigation and testing of therapeutic interventions to ameliorate or potentially r
289 observations reveal opportunities for novel therapeutic interventions to improve graft outcomes as w
291 ity in sensory behavior, informing metabolic therapeutic interventions to restore perceptual abilitie
292 toms and complications of CKD; develop novel therapeutic interventions to slow CKD progression and re
294 is review article presents the pathogenesis, therapeutic interventions, treatment approaches, and str
295 identify N17 as a potential target for novel therapeutic intervention using the molecular tweezer CLR
296 immune-mediated diseases and to develop new therapeutic interventions using glycan-binding proteins.
297 ogy in the context of neurologic disease and therapeutic interventions, which may lead to the develop
298 an help guide the rational design of complex therapeutic interventions, which target the colorectal c
299 Our analysis demonstrates that successful therapeutic intervention will be highly dependent on the
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