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1                           This enzyme has also emerged as a therapeutic target for cardiovascular disease due to its abil
2             Thus, cardiac D1R has the potential to become a therapeutic target for preventing heart failure-associated ve
3 ulate diversity in neuronal sensitization and may provide a therapeutic target for many neuroinflammatory pain conditions
4   Collectively, our results suggest that IL-27 represents a therapeutic target to limit susceptibility and improve infect
5  of vascular tone and BP and suggest a novel mechanism, and therapeutic target, for aging-induced essential hypertension
6                Thus, p38beta MAPK is a central mediator and therapeutic target of cancer-induced muscle wasting.
7               Toll-like receptor 7 (TLR7) is an established therapeutic target in myriad autoimmune disorders, but no TLR
8 making Ca(2+)-CaM dependent regulation of RyR2 an important therapeutic target for cardiac alternans.
9 one H3 lysine 27 (H3K27me3) and has emerged as an important therapeutic target with inhibitors targeting its methyltransf
10 ally exclusive in leukemic sub-clones, causing dichotomy in therapeutic target choices.
11                                                       A key therapeutic target in PD is alpha-synuclein (alphaS), which i
12 ls (GSCs), that maintain the bulk tumor and represent a key therapeutic target.
13 l, skeletal muscle and hepatic function may represent a new therapeutic target for treating disordered energy metabolism
14 receptor subtype 2 (CB2R) represents an interesting and new therapeutic target for its involvement in the first steps of
15                                TPCs might represent a novel therapeutic target against HIV-1 infection and HIV-associated
16  In some cases, this has resulted in the pursuit of a novel therapeutic target and resultant clinical trial.
17                                     Thus, we report a novel therapeutic target expressed on a range of immune cells with
18  AIF-mediated apoptosis, and that AIF may represent a novel therapeutic target for HPV-induced cervical cancer.
19           These findings support mTOR activation as a novel therapeutic target for iMCD, which is being investigated thro
20 ys in obese asthmatic Th cells, identifying them as a novel therapeutic target for obesity-related asthma, a disease that
21 k between inflammation and metabolism, representing a novel therapeutic target for patients with obesity.
22 ycolysis by activating PFKFB3 and suggest PFKFB3 as a novel therapeutic target in AML.
23 d pressure-dependent outflow suggests potential for a novel therapeutic target in treating glaucoma.
24 m performance rather than autophagy and may provide a novel therapeutic target to treat cardiac proteinopathies.
25 st that the CD82-PKCalpha signaling axis may be a potential therapeutic target for attenuating chemoresistance signaling
26    Therefore, the inhibition of NETs represents a potential therapeutic target for COVID-19.
27 er, our findings uncover a druggable pathway as a potential therapeutic target for disorders with reduced SHANK3 dosage,
28 e in GBM invasion and suggest GBP2 may serve as a potential therapeutic target for inhibiting GBM invasion.
29 tic HAX-1 inactivation suggest that this may be a potential therapeutic target for metabolic disease intervention.
30 rational failure of oligodendrocytes and offers a potential therapeutic target for prevention of diffuse WMI in premature
31 is and that the NLRP3-dependent inflammasome is a potential therapeutic target for the cutaneous manifestations of autoim
32 T1-related cancer stemness networks, marking it a potential therapeutic target in colorectal cancer.
33 ntenance of the CSC phenotype, indicating it is a potential therapeutic target in HNSCC.
34 y LYN as a key regulator of pMo development and a potential therapeutic target in inflammatory diseases regulated by pMos
35 mmunity and implicate the MCL/MINCLE pathway as a potential therapeutic target in MS.
36                                   Thus, Plk1 is a potential therapeutic target in pediatric B-ALL and selective targeting
37           Previous results showed that HMGA2 is a potential therapeutic target of anticancer and anti-obesity drugs by in
38 fficacy of immunotherapy and identify ALKBH5 as a potential therapeutic target to enhance immunotherapy outcome in melano
39 contributes to immune activation and represents a potential therapeutic target to prevent non-acquired immunodeficiency s
40  for parasite infection of host macrophages and a potential therapeutic target.
41 or this reason the system could represent a novel potential therapeutic target for DS.
42 eness and patient survival and represents a novel potential therapeutic target to tackle this devastating pathology.
43         Our study points to CeA(GA) as a potential powerful therapeutic target for alleviating chronic pain.
44 G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharma
45 is highly expressed in the brain and represents a promising therapeutic target for the treatment of Huntington's disease
46               These findings establish FATP4 as a promising therapeutic target to improve the visual cycle, as well as su
47 nical trials using L-AZM as a novel and clinically relevant therapeutic target to improve cardiac recovery and reduce hea
48 y updates from the IUPHAR/BPS Guide to Pharmacology and the Therapeutic Target Database.
49  of extravasation and suggest that it may represent a valid therapeutic target for inhibiting metastasis.
50 increases in BLA activity mediated by LC-NE may be a viable therapeutic target for individuals with stress- and trauma-re