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1                                           Is there an objective and systematic framework for designin
2 rmulas motivates an interesting question: Is there an optimal feedback strategy to regulate the synth
3                                              There appears to be both an anticipatory effect (future
4                                              There are a large number of published studies with depos
5                                              There are a number of techniques to represent and organi
6                                     However, there are conflicting perspectives on the roles of mosai
7 ession is regulated in epithelial cells, and there are conflicting reports about whether it plays any
8 )-A has been implicated in this context, but there are conflicting reports as to whether it is a cont
9                                              There are currently no simple, standardized, objective a
10                                              There are currently no therapies to directly inhibit hep
11                                 Furthermore, there are currently no validated biomarkers that predict
12                               In conclusion, there are distinct distribution patterns of circumferent
13                                     Although there are distinct ocular advantages to anti-VEGF pharma
14 any different histone chaperones reveal that there are few commonalities in their folds.
15                                              There are few data examining how sorafenib starting dose
16  psoriasis has been associated with obesity, there are few prospective studies with objective measure
17 ineligible for revascularization procedures, there are few therapeutic alternatives, leading to amput
18  the high or low gene flux modes, suggesting there are genetic as well as ecological drivers of horiz
19 an interfere with the induction of NAbs, but there are good arguments in favor of suppressing such "o
20                                              There are limited data on aspirin (ASA) desensitization
21                                              There are long-standing interests in the potential benef
22                                              There are mainly five functional modules in TFBSbank aim
23                                              There are many "prehygiene" communities with sewage-cont
24                                              There are many diagnostic tests that are employed in the
25                                     However, there are many gastrointestinal and hepatic diseases for
26                  Over the entire dose range, there are negative mortality dose trends for all circula
27                                   Currently, there are no approaches to assess the rheological proper
28           However, beyond BRCA1/2 mutations, there are no approved biomarkers for olaparib in high-gr
29                                     To date, there are no AR variant-specific treatments for CRPC.
30                            However, to date, there are no commercially available devices able to obta
31                                              There are no disease-modifying therapies for either FTD
32 ider communication and medication adherence, there are no empirical data on how the informational and
33  against MERS-CoV for humans or animals, and there are no large-scale clinical trials for therapies a
34                                              There are no proven treatments.
35                            To our knowledge, there are no published recommendations on the medical ma
36 m form to antimicrobial decontamination, and there are no quantitative models to study how biofilm mi
37 utations in the gene UBE3B However, to date, there are no studies that have determined the cellular o
38                                              There are no treatment options against MERS-CoV for huma
39                                              There are no widely accepted prognostic indices for extr
40 chnological parameters for whose measurement there are not accepted procedures.
41                                     Although there are numerous devices developed to isolate individu
42                                          Yet there are only a handful of studies demonstrating contro
43 y the vibrissae of a live seal and show that there are prominent signals at frequencies where the sea
44                         In cardiac myocytes, there are several Ca(2+) -sensitive potassium (K(+) ) cu
45                                   RATIONALE: There are several methods to measure cardiomyocyte and m
46               Despite sequence conservation, there are significant structural differences between mic
47                                              There are similar concerns with radiation, which especia
48                                     However, there are situations where connectivity exists without a
49  toward potential therapies have been taken, there are substantial obstacles that will need to be ove
50            Because of the nature of the ARG, there are two distinct features related to the waveguide
51 ides a unique starting point to determine if there are universal nonbiting genes in mosquitoes that c
52  for breast cancer-associated mortality, and there are unmet clinical demands for the discovery of ne
53                                              There are windows of opportunity in which vaccination wo
54 time, their enormous evolutionary diversity (there are yeast species in every subphylum of Dikarya) s
55                                              There as increases in ferulic acid levels occurred as a
56                                      Despite there being an extensive literature on the topic, the ac
57 rescribed appropriately to treat infections, there continue to be a large number of inappropriately p
58 hat, even if the Paris targets are realized, there could still be a significant adaptation imperative
59 nd results in the disease phenotype, because there does not appear to be an alternative in vivo recon
60                                        Since there exist numerous methods and techniques for scaffold
61 e association between body mass and fitness, there has been a genetic change towards lower body mass.
62                             In recent years, there has been a huge rise in the number of publicly ava
63                                Nevertheless, there has been a negligible amount of consideration of t
64                                              There has been a sharp increase in Medicare and out-of-p
65                                     Although there has been a sustained effort to reconstruct the dyn
66                                              There has been an approximately 10% net decrease in extr
67                   Despite these limitations, there has been an increase in the understanding of patho
68 stimulators of T cells during infection, and there has been an increasing interest in harnessing thes
69                                              There has been growing interest in the mechanical behavi
70                             In recent years, there has been growing public awareness and increasing a
71                                    Recently, there has been increasing awareness of novel attributes
72                                 In contrast, there has been less systematic study of antibody specifi
73                                     However, there has been only limited success in developing cold-h
74 e requirements for the 7-nm technology node, there has been tremendous progress in demonstrating the
75 s biological and pathological conditions and there have been active research efforts to develop high-
76                                     However, there have been few neurophysiological investigations of
77  of children with and without allergies, but there have been few studies on antibiotic use and allerg
78                                    Recently, there have been increased calls for advanced in vitro mu
79                                              There have been many studies in which the spatial patter
80                                    Recently, there have been several reports describing their applica
81                                              There have, though, been contrasting reports regarding t
82 ity, a 25% load reduction is required before there is 95% certainty of observing any hypoxic area red
83                        In south east England there is a 7% chance of exceeding the current rainfall r
84 xclusively by macroscopic techniques so far, there is a clear need for local-probe measurements.
85                                 As a result, there is a clear need to identify paleoclimate records e
86                                    Moreover, there is a clear relationship between the change in magn
87 ruses are ongoing in multiple countries, yet there is a dearth of mass rearing infrastructure specifi
88       Our objective was to determine whether there is a decline in the prevalence of AD in population
89                                              There is a decrease in 2- and 3-linked arabinose oligosa
90                                     However, there is a fundamental gap in our quantitative understan
91                                   Obviously, there is a general trend of predominance of Phax conform
92                                              There is a group which displays behavioural deterioratio
93                        Results indicate that there is a high degree of variability in SaMM use and th
94 some cases may respond initially to therapy, there is a high incidence of CLAD and poor survival afte
95 bare footedness, and poor housing, and still there is a high prevalence of allergic disease.
96 s often encountered in cancer treatment, and there is a lack of effective treatment.
97                                     However, there is a lack of knowledge about fecal microbiome comp
98                                     However, there is a lack of knowledge as to which drug pharmacoki
99                                     However, there is a lack of real-world data to support this estim
100                                              There is a lack of simple and validated severity assessm
101               This scoping review found that there is a large literature on how to modify the process
102  understanding the potential energy surface; there is a low barrier for the pseudopericylic [1,3]-NO
103                                              There is a major unmet need to identify high-risk patien
104                                              There is a need for a more refined, molecularly based cl
105                                              There is a need for hepatitis C virus (HCV) therapies wi
106                                              There is a need for new greener materials (than for exam
107  regulation of protein interactions in vivo, there is a need for techniques that can yield time-resol
108                                              There is a need to develop efficient statistical methods
109                                              There is a need to develop methods that are robust to pl
110                                              There is a need to ensure that the care and welfare for
111                                              There is a need to increase awareness of the impact of g
112                                Despite this, there is a paucity of information regarding characterist
113                                        Thus, there is a pressing need for more efficient processes.
114 escent noncanonical amino acid, we show that there is a rearrangement in the eag domain-CNBHD interac
115                                              There is a scarcity of data on the amount and distributi
116                                              There is a significant need to find biomarkers of respon
117 t theory with the axiom of choice (ZFC) that there is a simple nuclear nonseparable [Formula: see tex
118                                              There is a striking enrichment of longer-range interacti
119 ipin2 seipin3 and triple seipin mutants, but there is a striking increase in seed dormancy levels.
120  we show that despite these negative trends, there is a threefold increase in widespread extreme rain
121                                              There is also evidence of herd protection against the va
122 ics, which accounts for sex differences, but there is also evidence to support underlying genetic var
123 nd also at the aggregate level (G); however, there is ambiguous evidence for the existence of g when
124                                              There is an increasing appreciation for the role of the
125 bstruction in patients with aortic stenosis, there is an independent association between post-TAVR bl
126 nces of the various systems are limited, and there is an intensive search for highly efficient electr
127 at mimics one of the reaction intermediates, there is an overall decrease in HDX in the lid and adjac
128                 Our aim being to consider if there is an overall differential control of fR and VT th
129                               In particular, there is an unmet need in rapid, reliable detection of s
130                                   Therefore, there is an urgent need to develop a high-throughput and
131                                              There is an urgent need to develop an efficacious and af
132                                     However, there is an urgent need to rigorously estimate actual mo
133 itation (PR) improves exercise capacity, but there is conflicting evidence regarding its ability to i
134                                 Furthermore, there is considerable variation in multiple aspects of s
135  under natural conditions is challenging and there is currently little data from the wild.
136                               In particular, there is currently no consensus for the band gap and ele
137 uired by law in the majority of U.S. states, there is currently no standardized method of implementat
138 tify multiple disease-related mutations, but there is currently no systematic framework for translati
139 iew identifying 13 mammalian genes for which there is evidence for polycistronic expression via trans
140                                              There is evidence implicating the role of female sex hor
141                                              There is evidence of much higher radiation-associated re
142 tion within the enzyme active site; however, there is evidence that conformational restriction of the
143  which are widely used in consumer products, there is evidence that particle size and formulation inf
144                                              There is great interest in developing alternative and su
145                                              There is growing evidence that invasions foster eutrophi
146      535 Acknowledgements 536 References 536 There is growing evidence that life has been on land for
147                                     However, there is growing evidence to suggest that glucuronides c
148                                              There is growing interest in utilizing antibody-dependen
149                                              There is growing understanding of the oncogenic and tumo
150                                              There is limited understanding of the associations betwe
151  and anaerobically germinating embryos, when there is little cell division.
152 ing most individuals in an aging population, there is little consensus regarding its precise anatomic
153 te preparation has been extensively studied, there is little information about resistance of skin mic
154                                              There is little room for cropland expansion to increase
155                              INTERPRETATION: There is more than a 50% probability that by 2030, natio
156 f all known genetic variation, and therefore there is necessarily an imbalance between the small set
157 del predicts a weaker response to therapy if there is negative feedback from differentiated tumor cel
158         Together these findings suggest that there is niche-specificity to the placental microbiota a
159                                              There is no biomarker for diagnosing active tuberculosis
160                                      To date there is no clear information on the role of VEGF-A in I
161  Our data suggests that in Sargassum muticum there is no connection between phyllotaxis and the apica
162                               Unfortunately, there is no effective pharmacologic approach for treatin
163                                              There is no evidence that, in clinical practice, lansopr
164 auses of death may diminish the benefit, and there is no evidence to recommend screening in this grou
165                                   Currently, there is no generally accepted model to predict outcomes
166 cillations start to decay immediately, since there is no means to restitute the energy dissipated.
167                                     To date, there is no regenerative treatment available.
168                                     To date, there is no standardized method for analyzing multiple-s
169                       A core problem is that there is no sufficiently fast diagnostic test to guide c
170                                              There is no support for the adaptive coevolution of the
171                                              There is now an opportunity to apply knowledge from NM t
172  accurate than several existing methods when there is one allele per species, although STELLS2 is slo
173 ompletion of The Cancer Genome Atlas (TCGA), there is opportunity for systematic analyses of the enti
174                                     Although there is some evidence for allergy-promoting effects in
175                                              There is still a high rate of short-term mortality and c
176                                              There is substantial room for improvement in diet qualit
177                     Recent studies show that there is sufficient cone structure remaining in the cent
178                                   We believe there is sufficient evidence to support referring or dai
179  Soc molecules reinforce the structure where there is the greatest strain in the gp23 hexagonal latti
180                     Conversely, knowing that there is unexplained residual phylogenetic information s
181                        Our results show that there is variability for circadian traits in the wild ba
182                                     However, there is very little information on how the clock influe
183                                              There is widespread interest in the relationship between
184                                  At present, there is, however, insufficient evidence for the primary
185 uce prevalence, but our results suggest that there may also be large benefits to vaccinating previous
186 e did not improve outcomes overall, although there may have been some effect among Fusarium ulcers.
187     Differences of opinion regarding whether there may, or may not, have been protective efficacy in
188 236)U by the Elbe River is negligible, while there might be a maximum input of 12 g/yr via the Baltic
189 iduals of European ancestry, suggesting that there might be different genetic factors affecting susce
190  metabolic homeostasis, we hypothesized that there might be thermogenic lipokines that activate BAT i
191 crease in skeletal density, we conclude that there must be biochemical influences that probably inclu
192 ge and advances in prevention and treatment, there remain many questions about this decline.
193                                     However, there remains a need to anticipate supply given the rapi
194 lume fluid administration for major surgery, there remains little consensus on optimal strategies, du
195                                              There remains the need, however, for a soluble, versatil
196 e needle biopsies used for genomic analysis, there should be a preference for using lower gauge needl
197                                              There should be close monitoring, for the increased risk
198                                              There, the conformation of transmembrane helices constit
199 At the latest median follow-up of 19 months, there was 100% (death-censored) renal allograft survival
200  18 (7.6%) of 237 patients at screening, and there was a clear age gradient.
201                                              There was a considerable degree of heterogeneity in the
202 icrobiota composition was heterogeneous, but there was a correlation between NET complexes and both m
203                                 Furthermore, there was a dose-dependent association between the preva
204                                              There was a graded association also in the cosibling des
205                                              There was a high agreement regarding sensibility of the
206                                              There was a quenching effect of the honey matrix on lept
207                           Following the MIP, there was a robust induction of depressed mood in the co
208  while total FoxM1 levels remained constant, there was a significant decrease of the phosphorylated,
209                                 In addition, there was a significant group effect showing higher trac
210                                              There was a significant increase in the kinetic uptake c
211                                              There was a significant interaction between travel time
212                                              There was a significant interaction of BCPR with age.
213                                              There was a significant reduction of left ventricular vo
214                                              There was a small non-clinically relevant but statistica
215 in and provided 218 +/- 8 kcal/d.During CVVH there was a substantial net uptake of both glucose and c
216 ntent analysis of 200 citing articles showed there was a tendency to describe the cell line in accord
217                                              There was a wide variation in the number of opioid pills
218                                              There was also no improvement in the rate of successful
219 ce decreased after antibody binding, because there was an additional amount of protein bound to the s
220                        If parents consented, there was an additional randomisation (1:1) of type of h
221                                              There was an association between %5 mC and LTL in female
222  the primary model included geographic site, there was an attenuated nonsignificant association betwe
223 ature control mode (60 degrees C/50 W) until there was approximately 80% EGM amplitude reduction.
224  cases (95% confidence interval, 1.3%-6.7%), there was clinically meaningful diagnostic discordance,
225                          In 5 of 6 patients, there was concordance in the number of metastases identi
226 E. lecanii-corni and E. lavatrina, for which there was considerable log score overlap.
227 of 516 MSM who had at least 3 clinic visits, there was general stability across risk classes; MSM had
228 20.16+/-0.35 degrees C, which indicated that there was good thermal stability of the starch.
229                                              There was limited correlation between outcomes for SAVR
230                                     Although there was loss of abundance relative to uncrowded myoglo
231                                 In controls, there was minimal change in J-ST point elevation, conduc
232 0,170 person-years of follow-up (1982-2012), there was no association between risk of hearing loss an
233                                              There was no association between stent fracture and the
234                                              There was no correlation between subjective complaints a
235 ency team implementation across study sites, there was no difference between predicted (hospital mean
236  20 patients who received intensive therapy, there was no difference between the proportion of respon
237                                 In addition, there was no difference in mean visual outcome of the fi
238                                     However, there was no difference in nonfatal stroke, cardiovascul
239 as more frequent with WBRT than with SRS and there was no difference in overall survival between the
240                                              There was no difference in the primary endpoint of day 1
241 able rhythms (from 58.9% to 69.2%; P<0.001), there was no difference in unadjusted rate of successful
242 ditions through a TBK1-binding domain (TBD), there was no direct impact of the TBD on viral replicati
243                                              There was no effect on endothelial function as measured
244                                              There was no evidence of a threshold in the exposure-res
245                                              There was no evidence of improvement in complete respons
246                                              There was no evidence that iCST has an effect on cogniti
247 ition, as with intracerebroventricular CGRP, there was no general increase in anxiety as measured in
248                                              There was no increase in vascular occlusive events with
249                                              There was no interference in protection between the diff
250                                              There was no shift to shorter acyl chain lengths observe
251                                              There was no significant association between younger age
252                                              There was no significant association with sex or Chinese
253                                              There was no significant between-group difference in cha
254 %/y [95% CI, -5.6% to -1.0%], P = .004), but there was no significant change in the combined outcome
255                                              There was no significant difference in mutation load in
256                                              There was no significant difference in the levels of inh
257 f a trial involving patients undergoing PCI, there was no significant difference in the rate of targe
258                                      Results There was no significant difference in the size or shape
259 , 2.5; 95% CI, 1.1 to 6.0; P = .03), whereas there was no significant effect of negative microscopic
260                                              There was no survival difference between PB-type cancers
261 URT possess different pathogenic properties, there was significant overlap in the most upregulated ho
262                                              There was some evidence for a stronger association at hi
263 ed for CD4 cell count and ART duration), and there was some evidence of association with HSIL-CIN2+ (
264                                              There was some evidence of heterogeneity by tumor grade
265                    That work determined that there was substantial agreement on the need for a mixtur
266                                Surprisingly, there was very little difference between the two proteom
267                                              There were 1290 eligible patients, 259 treated for 1-3 d
268       Data from 2093 patients were analyzed; there were 1293 men (61.8%) and 800 women (38.2%) (media
269                                              There were 13 trials (n = 9850) that included kidney tra
270                                              There were 132 eligible thrombectomy patients and 132 ma
271                                              There were 29823 patients (12822 women and 17001 men; me
272                                              There were 63 new cases of IIH, yielding an overall age-
273                                              There were 922 subjects in the ICS+ group (248 African A
274                                   At day 90, there were also relative improvements in tear breakup ti
275                                              There were also significant differences in growth of EFW
276                                              There were also some slight differences in gepotidacin d
277                                              There were clinical trends in permanent stoma rates and
278 el 2 facilities in the 3 countries for which there were data.
279                                              There were five cohort studies, one case series, and sev
280                                              There were lower levels of in vitro-polarized TH2 cells
281                                              There were many similarities but, crucially, some differ
282                                              There were nine treatment-related deaths.
283                                              There were no adverse events either immediately or at 2-
284 ceptability of the intervention was high and there were no adverse events.
285                                              There were no associations between induction, graft loss
286 ar glaucoma was noted in 1 patient (2%), and there were no cases of corneal opacity.
287                                              There were no differences in allergic disease between LE
288 y development of intestinal inflammation and there were no differences in previously published metabo
289                                              There were no indications of acute toxicity up to 7 days
290                                              There were no significant differences between groups in
291 nts and family members compared to controls, there were no significant differences in allele frequenc
292 eneficiaries treated by a general internist, there were no significant differences in overall 30-day
293                                              There were no significant differences in transplant and
294                                              There were no significant interactions of genotypes with
295                                              There were not enough studies for meta-analysis in other
296                                              There were significant correlations between COPD readmis
297                                              There were significantly more cases categorised as non-A
298                                              There were three overall themes: Effects of day shift le
299                         Until very recently, there were two main evolutionary narratives for this rat
300                               On ultrasound, there were well-defined, heterogeneous, predominantly hy

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