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1 ated with therapeutics targeting the IL-1 pathway; however, there are a number of identified CAPS patients who show only
5 t how LMP1 expression is regulated in epithelial cells, and there are conflicting reports about whether it plays any role
6 th factor (VEGF)-A has been implicated in this context, but there are conflicting reports as to whether it is a contribut
12 al studies of many different histone chaperones reveal that there are few commonalities in their folds.
13 Although psoriasis has been associated with obesity, there are few prospective studies with objective measures.
14 tients who are ineligible for revascularization procedures, there are few therapeutic alternatives, leading to amputation
15 all into either the high or low gene flux modes, suggesting there are genetic as well as ecological drivers of horizontal
17 es against V3 can interfere with the induction of NAbs, but there are good arguments in favor of suppressing such "off-ta
27 en patient-provider communication and medication adherence, there are no empirical data on how the informational and rela
28 eatment options against MERS-CoV for humans or animals, and there are no large-scale clinical trials for therapies agains
29 e potential to advance rational vaccine development but yet there are no licensed vaccines against malaria based on antig
31 a in the biofilm form to antimicrobial decontamination, and there are no quantitative models to study how biofilm might b
32 Observational data in this area are conflicting, and there are no randomized clinical trials to guide practitioner
33 mal recessive mutations in the gene UBE3B However, to date, there are no studies that have determined the cellular or enz
38 Multi-antigen vaccines are under development, and there are presently far more candidate antigens than antigen
39 nals received by the vibrissae of a live seal and show that there are prominent signals at frequencies where the seal tac
44 the fact that there is rapidly accruing literature on CBCT, there are still no current evidence-based guidelines on its n
45 the first steps toward potential therapies have been taken, there are substantial obstacles that will need to be overcome
48 W. smithii provides a unique starting point to determine if there are universal nonbiting genes in mosquitoes that could
49 the main reason for breast cancer-associated mortality, and there are unmet clinical demands for the discovery of new bio
50 At the same time, their enormous evolutionary diversity (there are yeast species in every subphylum of Dikarya) sparke
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