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1 89% in the mesophilic reactor and 85% in the thermophilic.
6 ysis of the recently sequenced genome of the thermophilic actinomycete Thermobifida fusca revealed an
7 that organisms develop diverse strategies of thermophilic adaptation by using, to a varying degree, t
8 ma) relied in their evolutionary strategy of thermophilic adaptation on "sequence-based" mechanism of
9 m a pair of highly homologous mesophilic and thermophilic adenylate kinases, we generated a series of
10 ynamics are investigated in two mutants of a thermophilic alcohol dehydrogenase (ht-ADH): Y25A (at th
11 tic parameters in relation to the homologous thermophilic alcohol dehydrogenase (htADH) from Bacillus
13 function of temperature in two variants of a thermophilic alcohol dehydrogenase: W87F and W87F:H43A.
14 ransfer step catalyzed by a series of mutant thermophilic alcohol dehydrogenases (ht-ADH), presenting
16 Naegleria fowleri is a climate-sensitive, thermophilic ameba found in the environment, including w
17 Naegleria fowleri is a climate-sensitive, thermophilic ameba found in warm, freshwater lakes and r
18 iter, is the highest reported thus far for a thermophilic anaerobe, although further improvements are
19 gain insights into mannan degradation by the thermophilic anaerobic bacterium Caldanaerobius polysacc
20 oxidation activator protein (CooA) from the thermophilic anaerobic bacterium Carboxydothermus hydrog
21 ing Thermoanaerobacterium saccharolyticum, a thermophilic anaerobic bacterium that ferments xylan and
24 s and intI1 decreased in all microcosms, but thermophilic anaerobic digestion, alkaline stabilization
25 c digestion, mesophilic anaerobic digestion, thermophilic anaerobic digestion, pasteurization, and al
26 g insight into the physiology and ecology of thermophilic anaerobic methanotrophy and suggesting that
29 ) (ATCC BAA-2073, JCM 16842) is an extremely thermophilic, anaerobic bacterium capable of hydrolyzing
34 lap between quinone compositions of distinct thermophilic and halophilic archaea and bacteria may ind
35 lic homologue, BBL, was less stable than the thermophilic and hyper-thermophilic variants (E3BD and P
37 etal uptake behavior previously observed for thermophilic and hyperthermophilic superoxide dismutases
39 ere performed to unfold a homologous pair of thermophilic and mesophilic cold shock proteins at high
40 res distinguish intersubunit linkages of the thermophilic and mesophilic enzyme Bacillus subtilis cho
43 the evolutionarily distant F-type motors of thermophilic and mesophilic origins, and they differ onl
44 ndant in crenarchaeota, which thrive in both thermophilic and nonthermophilic environments, with wide
45 upport the notions that Precambrian life was thermophilic and that proteins can evolve from substrate
47 sed to show a dramatic preference in certain thermophilic archaea and bacteria for disulfide bonds wi
48 ethods the number of viruses identified from thermophilic Archaea and Bacteria is still very small.
49 oses the process of allopatric speciation in thermophilic Archaea and brings us closer to a generaliz
56 evidence that four different mesophilic and thermophilic archaeal RNase P holoenzymes, reconstituted
58 re, we report the structure of Dim1 from the thermophilic archaeon Methanocaldococcus jannaschii.
59 ted in vitro the RNase P holoenzyme from the thermophilic archaeon Pyrococcus furiosus (Pfu) and furt
60 studies on the DNA alkyltransferase from the thermophilic archaeon Sulfolobus solfataricus (SsOGT).
62 a novel, low molecular weight TrxR from the thermophilic archaeon Thermoplasma acidophilum ( taTrxR)
63 e characterization of an RNA ligase from the thermophilic archaeon, Methanobacterium thermoautotrophi
64 t exploits protein engineering to "humanise" thermophilic archeal surrogate proteins as targets for s
65 conditions that allow direct comparison to a thermophilic (B. stearothermophilus) ortholog, Ec-DHFR a
67 utant subcomplex of the F(1)-ATPase from the thermophilic Bacillus PS3 (TF(1)), free of endogenous nu
69 uridine at position 54 stabilizes tRNAs from thermophilic bacteria and hyperthermophilic archaea and
70 the physiology and biochemistry of anaerobic thermophilic bacteria and, more lately, to anaerobic fun
71 r instance with a cluster of sulfur-reducing thermophilic bacteria coming together irrespective of th
72 Phenol hydroxylase gene cloning from the thermophilic bacteria Geobacillus thermoglucosidasius wa
74 esent the crystal structure of BamD from the thermophilic bacteria Rhodothermus marinus refined to 2.
75 very stable members of this superfamily from thermophilic bacteria to use as robust engineerable part
76 e cases of operon differences occurred among thermophilic bacteria, suggesting a much higher incidenc
77 the isolated HisF TIM barrel domain from the thermophilic bacteria, Thermotoga maritima, enabled an N
85 res of the large terminase nuclease from the thermophilic bacteriophage G20c show that it is most sim
88 ve determined the structure of NusB from the thermophilic bacterium Aquifex aeolicus and studied the
89 temperatures, we sequenced the genome of the thermophilic bacterium Caldanaerobius polysaccharolyticu
92 ystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans
93 dihydrofolate reductase from the moderately thermophilic bacterium Geobacillus stearothermophilus (B
94 Here, we show that the Cas9 protein from the thermophilic bacterium Geobacillus stearothermophilus (G
95 cterized a thermostable NOS homolog from the thermophilic bacterium Geobacillus stearothermophilus (g
96 a nisin analog encoded on the genome of the thermophilic bacterium Geobacillus thermodenitrificans N
97 hosphogluconate dehydrogenase (6PGDH) from a thermophilic bacterium Moorella thermoacetica with rever
98 xide/oxygen binding (H-NOX) protein from the thermophilic bacterium Thermoanaerobacter tengcongensis,
99 teractions of SmpB.SsrA orthologues from the thermophilic bacterium Thermoanaerobacter tengcongensis.
100 glC ORF encoding a beta-glucosidase from the thermophilic bacterium Thermobifida fusca and inserted i
103 n of gene expression during infection of the thermophilic bacterium Thermus thermophilus HB8 with the
104 T4P and natural transformation of DNA in the thermophilic bacterium Thermus thermophilus requires a u
105 ntibiotic-resistant mutants of the extremely thermophilic bacterium Thermus thermophilus, a species w
108 he dioxygen complex of the NOS enzyme from a thermophilic bacterium, Geobacillus stearothermophilus (
110 nteract with one another to generate extreme thermophilic behavior and are responsible for approximat
111 hat three residues in the active site of the thermophilic beta-1,4-xylanase from Nonomuraea flexuosa
112 d to ferment milk to obtain yogurt belong to thermophilic, bile-sensitive species of lactic acid bact
115 gment, 3'-->5' exo(-) Klenow DNA polymerase, thermophilic Bst DNA polymerase large fragment, Thermina
118 ocellum wild-type strain YS is an anaerobic, thermophilic, cellulolytic bacterium capable of directly
119 Clostridium thermocellum is an anaerobic, thermophilic, cellulolytic, and ethanogenic bacterium.
121 icus UBT1 has been described as a moderately thermophilic chemolithoautotroph with a novel nitrogenas
126 to microcrystalline cellulose under aerobic, thermophilic conditions using green waste compost as the
131 hows high homology with mesophilic and other thermophilic cpn10 sequences, except for a 25-residue C-
132 The Y-family DNA polymerase Dpo4, from the thermophilic crenarchaeon Sulfolobus solfataricus P2, of
133 overy of ammonia oxidation by mesophilic and thermophilic Crenarchaeota and the widespread distributi
134 enomes of the two closely related freshwater thermophilic cyanobacteria Synechococcus sp. strain JA-3
135 re we describe a novel pair of Phys from two thermophilic cyanobacteria, Synechococcus sp. OS-A and O
139 e discovered a tetrameric form of PSI in the thermophilic cyanobacterium Chroococcidiopsis sp TS-821
140 agnesium chelatase H subunit, ChlH, from the thermophilic cyanobacterium Thermosynechococcus elongatu
141 ize the cyanobacteriochrome Tlr0924 from the thermophilic cyanobacterium Thermosynechococcus elongatu
142 highly active dimeric b(6)f complex from the thermophilic cyanobacterium Thermosynechococcus elongatu
143 complex of oxygenic photosynthesis from the thermophilic cyanobacterium, Mastigocladus laminosus, an
144 sis of the cytochrome b(6)f complex from the thermophilic cyanobacterium, Mastigocladus laminosus, in
145 cally improve the orientation of PSII from a thermophilic cyanobacterium, Thermosynechococcus elongat
148 nd finally, how he extended these studies to thermophilic desert ants in other deserts of the world,
149 centered on Cataglyphis have rendered these thermophilic desert ants model organisms in the study of
151 y (HDX-MS) as a function of temperature in a thermophilic dihydrofolate reductase from Bacillus stear
152 rmincola ferriacetica is a recently isolated thermophilic, dissimilatory Fe(III)-reducing, Gram-posit
153 rporated into DNA by selected mesophilic and thermophilic DNA polymerases and the resulting primer ex
155 milar communities were observed in companion thermophilic enrichments on insoluble wheat arabinoxylan
156 ORFs from other organisms living in the same thermophilic environment to produce the type strain of P
159 nzyme from E. coli (EcDHFR) and the dimeric, thermophilic enzyme from Thermotoga maritima (TmDHFR).
161 ponding mesophilic (Ms) enzymes, because the thermophilic enzymes are less flexible (assuming that fl
162 ion in mesophiles can be aided by the use of thermophilic enzymes as starting points for protein desi
164 ons presume that the reduced dynamics of the thermophilic enzymes is the reason for their reduced cat
168 studies of RNA polymerases (RNAPs) from the thermophilic eubacteria Thermus aquaticus (Taq) and Ther
172 e, these genomes are the first described for thermophilic eukaryotes and the first complete telomere-
174 obacter pseudethanolicus 39E (ATCC 33223), a thermophilic, Fe(III)-reducing, and fermentative bacteri
175 cyanobacterium Synechocystis PCC6803 and the thermophilic, fermentative bacterium Pelotomaculum therm
176 ponse to the nonconserved E77 present in the thermophilic Fpg sequences used for the crystallography
178 potential reservoir of thermostable enzymes, thermophilic fungi are amenable to manipulation using cl
179 e we describe and compare the genomes of two thermophilic fungi, Myceliophthora thermophila and Thiel
180 the junction-resolving enzyme GEN1 from the thermophilic fungus Chaetomium thermophilum and expresse
181 res of the separase protease domain from the thermophilic fungus Chaetomium thermophilum, alone or co
182 e most stable parent, CBH II enzyme from the thermophilic fungus Humicola insolens, which suggests th
188 rAB is a heterodimeric ABC exporter from the thermophilic Gram-negative eubacterium Thermus thermophi
189 complex, and the reaction center (RC) in the thermophilic green phototrophic bacterium Chloroflexus a
190 ne boundary, while trans-Arctic dispersal in thermophilic groups may have been limited to the early E
191 e because it is halophilic, alkaliphilic and thermophilic, growing optimally at 3.5 M Na(+), pH(55 de
192 s in the lake, including both mesophilic and thermophilic habitats, had multiple virophage genotypes.
194 mined the crystal structure of DGGR from the thermophilic heterotrophic archaea Thermoplasma acidophi
195 and high temperature unfolding kinetics of a thermophilic homolog, Thermobifida fusca protease A (TFP
196 t thermal constraints by adding a moderately thermophilic homologue to the previously characterized m
198 end the frontier of metabolic engineering in thermophilic hosts, have the potential to significantly
199 cterized the conformational stability of the thermophilic HPr proteins using thermal and solvent dena
203 experimental biogas plant composed of three thermophilic leach bed reactors (51-56 degrees C) follow
204 etate formation at different OLRs within the thermophilic leach bed reactors as well as a negligible
206 while the folding core region determines the thermophilic-like behavior of this family of proteins, t
208 Archaea such as Metallosphaera sedula are thermophilic lithoautotrophs that occupy unusually acidi
210 ly been solved to 3.0-A resolution using the thermophilic Mastigocladus laminosus whose genome has no
212 genome of strain Exiguobacterium sp. AT1b, a thermophilic member of the genus Exiguobacterium whose r
214 studies that have suggested that, in certain thermophilic microbes, disulfide bonds play a key role i
217 45 degrees C) resulted in the emergence of a thermophilic microbial community specialized in fermenta
220 iments of the Guaymas Basin are inhabited by thermophilic microorganisms, including anaerobic methane
221 cations of phenotype arrays to anaerobic and thermophilic microorganisms, use of the plates in stress
222 (Moapa coriacea) is a critically endangered thermophilic minnow native to the Muddy River ecosystem
224 anosarcina mazei Go1 A-ATP synthase, and the thermophilic motor alpha3beta3gamma, from Geobacillus st
227 ect numerous redox enzymes, particularly for thermophilic ones, which can generate NAD(P)H reacted wi
229 In particular, it has been suggested that thermophilic or hyperthermophilic (Tm) enzymes have lowe
230 to design RNases H that display the desired thermophilic or mesophilic properties, as defined by the
231 Here we report that P450s derived from a thermophilic organism and containing an iridium porphyri
232 [a]P-N2-dG (G*), by UvrABC nuclease from the thermophilic organism Bacillus caldotenax was investigat
234 :quinone oxidoreductase (complex I) from the thermophilic organism Thermus thermophilus HB8 has been
236 hydrofolate reductase (DHFR) from a moderate thermophilic organism, Bacillus stearothermophilus, has
237 first structure for a monomeric DHFR from a thermophilic organism, indicating a high degree of conse
239 plain the high optimal growth temperature in thermophilic organisms and are in excellent quantitative
241 ochondrial carriers from both mesophilic and thermophilic organisms exhibit poor stability in mild de
242 coming limitations include sourcing CAs from thermophilic organisms, using protein engineering to evo
250 g point, Bryant et al. have discovered a new thermophilic phototroph from a poorly characterized bact
251 genus Caldicellulosiruptor contains the most thermophilic, plant biomass-degrading bacteria isolated
253 ), we discovered three related proteins from thermophilic prokaryotes, which we grouped into a novel
255 terise the transition state for folding of a thermophilic protein at the relatively high temperature
258 on of the MD trajectories indicates that the thermophilic protein samples conformations productive fo
259 low the same unfolding pathway, but with the thermophilic protein showing much slower unfolding.
262 derstand the origin of enhanced stability in thermophilic proteins by analyzing thermodynamic data fo
263 ise comparisons of homologous mesophilic and thermophilic proteins can help to identify the energetic
264 structural features normally associated with thermophilic proteins such as an increase in salt bridge
266 d state is encoded in the sequences of these thermophilic proteins, we subjected the RNase H from Chl
270 Cel7A) from mesophilic Hypocrea jecorina and thermophilic Rasamsonia emersonii and two variants of th
271 ow fiber membrane (HFM) module in continuous thermophilic reactors, CO did not inhibit the process ev
272 was almost no phycobilisome mobility in the thermophilic red alga Cyanidium caldarium that was not c
273 unction in mesophilic red algae; however, in thermophilic red algae, this process is replaced by nonp
275 stablishes a system to comprehensively study thermophilic replisomes and evolutionary links between a
276 emical attractants E. coli exhibits a steady thermophilic response, the magnitude of which decreases
277 ormational basis for reduced activity of the thermophilic ribonuclease HI enzyme from Thermus thermop
278 y important when using crystal structures of thermophilic ribosomes to interpret genetic results from
279 vable that phenotypes of mutations affecting thermophilic ribosomes, for instance, will be influenced
280 In this work, we describe the ability of the thermophilic RNA ligase MthRnl from Methanobacterium the
283 he genome of Heliobacterium modesticaldum, a thermophilic species belonging to this unique group of p
284 ectra (MALDI-TOF-MS) of cell lysates of five thermophilic species of Campylobacter: jejuni, coli, lar
285 served composition of the same set in extant thermophilic species than in extant mesophilic species,
286 roteins have been analyzed from a variety of thermophilic species, suggesting different structural fe
288 se trends in SRR, members of the potentially thermophilic, spore-forming, Desulfotomaculum were detec
289 inated by a single phylotype affiliated with thermophilic sulfate reducers belonging to Firmicutes.
291 Dpo4, an archetypal Y-family member from the thermophilic Sulfolobus solfataricus, was used to extend
293 ferences in the catalytic parameters between thermophilic Thermus aquaticus and mesophilic Deinococcu
295 tro at high temperature, making it the first thermophilic topoisomerase IB characterized so far.
296 (rRNA and tRNAs) in A. cellulolyticus showed thermophilic traits suggesting the importance of adaptat
298 ease of ordered water molecules and, for the thermophilic variant, a relaxation of monomer-tertiary s
300 the novel genomes, one belongs to a putative thermophilic virus infecting the bacterium Hydrogenobacu
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