ライフサイエンスコーパス: thermosensitive

1 yeast cell growth, but sec28 Delta cells are thermosensitive.

2 inducible, and mutants deficient in TPS5 are thermosensitive.

3 heat-shock response in vivo, rendering cells thermosensitive.

4 y the addition of Casamino Acids, and it was thermosensitive.

5 The prevalence of thermosensitive Adelta-fibers was too low to permit comp

6 o preferentially enhance the regeneration of thermosensitive afferents, suggesting that it may play a

7 tify powerful genetic interactions between a thermosensitive allele (sec14-1(ts)) of the structural g

8 Yeast containing a thermosensitive allele in the gene encoding Hsp90 also e

9 Schizosaccharomyces pombe strain carrying a thermosensitive allele of DNA polymerase delta (pol delt

10 In this work, thermosensitive, amine-reactive and amine-functionalized

11 mutants lacking portions of this region are thermosensitive and arrest with highly elongated buds an

12 the mitochondrial respiratory complexes were thermosensitive and function inefficiently.

13 llowed characterisation of mechanosensitive, thermosensitive and gustatory afferents.

14 d relevance of the nucleocapsid, we analyzed thermosensitive and inducible mutants in the L4R gene.

15 D sensory neurons, which are extraordinarily thermosensitive and respond to thermal fluctuations at t

16 soil microbiome, inducing the replacement of thermosensitive bacterial species with more thermotolera

17 ts cultivation temperature (Tc) and exhibits thermosensitive behaviors at temperatures relative to Tc

18 Here we report the synthesis of a thermosensitive, biodegradable hydrogel consisting of bl

19 from the protein macroinitiators resulted in thermosensitive BSA-polyNIPAAm and lysozyme-polyNIPAAm i

20 ent of airway sensory nerves, presumably the thermosensitive C-fiber afferents.

21 t activation of Kenyon cells by expressing a thermosensitive cation channel (dTrpA1) leads to a decre

22 deltorphin-II exerts its action directly on thermosensitive cells of the preoptic anterior hypothala

23 t and TrkA receptor tyrosine kinases and the thermosensitive channel TRPV1.

24 onserved molecular logic for gating of these thermosensitive channels by chemical agonists.

25 hock proteins (sHsps) prevent aggregation of thermosensitive client proteins in a first line of defen

26 Thermosensitive composite hydrogels that consist of a po

27 uch as formate, acetate, and lactate and the thermosensitive compound epigallocatechin gallate were r

28 Using a thermosensitive conjugative system, we provide evidence

29 To determine the thermosensitive contribution of persistent, TTX-sensitiv

30 nd exacerbated the mutation rate only in the thermosensitive deletion replication mutators but had no

31 on of deletion mutations specifically in the thermosensitive deletion replication mutators.

32 Furthermore, the thermosensitive DnaB allele prevents UV-induced DNA degr

33 eplication forks following inactivation of a thermosensitive DnaB helicase and found that they are di

34 d the use of a tumor-penetrating peptide and thermosensitive doxorubicin (DOX)-loaded nanoparticles i

35 of seven ventral HDB neurons (14%) remained thermosensitive during SB.

36 in iDEP devices experimentally employing the thermosensitive dye Rhodamin B (RhB) and compare the mea

37 With this thermosensitive dye, we imaged intracellular heat waves

38 We identified spontaneous suppressors of the thermosensitive eco1-1 allele in budding yeast.

39 However, in cells containing a thermosensitive eIF4E allele, their inability to grow at

40 e inserted into a conditionally replicating, thermosensitive, Escherichia coli-mycobacterial shuttle

41 een proposed to involve direct activation of thermosensitive excitatory transient receptor potential

42 e first application of a small molecule-type thermosensitive fluorescent dye, ERthermAC, to monitor t

43 e was analyzed molecularly in mutant strains thermosensitive for essential replication factors.

44 induction, showing that (i) Int is partially thermosensitive for excision at 42 degrees C and (ii) in

45 fusing it to FtsZ could partially suppress a thermosensitive ftsA mutation.

46 ing channel gating is a major determinant of thermosensitive gating.

47 lactic-co-glycolic acid) (PLGA-b-PEG-b-PLGA) thermosensitive gel (g-E).

48 a long-standing mystery; in particular, the thermosensitive genetic triggers for gonadal sex differe

49 named accordingly: the idnK gene, encoding a thermosensitive gluconate kinase, is monocistronic and t

50 oth human and Drosophila MMS19 cDNAs correct thermosensitive growth and sensitivity to killing by UV

51 The first class causes thermosensitive growth due to single amino acid substitu

52 -activated protein kinase and can rescue the thermosensitive growth of slt2 null mutants.

53 resulted in partial catalytic defects and a thermosensitive growth phenotype.

54 e first 75 amino acids (pta1-Delta75) causes thermosensitive growth, while the deletion of an additio

55 Petite cells were thermosensitive, had increased nuclear mutation frequenc

56 This thermosensitive hollow nanoparticle system provides an e

57 ntenna arrays (BNAs) with a submicron-thick, thermosensitive hydrogel coating.

58 shapes and sizes, and assessed the effect of thermosensitive hydrogels (poly(lactic-co-glycolic acid)

59 All seven strains were thermosensitive in the E. faecalis host FA2-2; colony mo

60 these properties, we propose that hTRPV3 is thermosensitive in the physiological range of temperatur

61 Thermosensitive injectable hydrogels have been used for

62 Hence, not only is VRL3 a thermosensitive ion channel but it may represent an addi

63 TRPV3 is a thermosensitive ion channel primarily expressed in epith

64 loid 3 (TRPV3) channel is a Ca(2+)-permeable thermosensitive ion channel widely expressed in keratino

65 Since this new liposome is thermosensitive, it can be used for ultrasound-mediated

66 o proprioceptive, and six principal types of thermosensitive, itch sensitive, type C low-threshold me

67 to INH and a related drug, ethionamide; (ii) thermosensitive lethality; and (iii) auxotrophy.

68 Thermosensitive liposomal doxorubicin was administered s

69 thermosensitive liposome (NTSL), traditional thermosensitive liposome (TTSL), and low temperature sen

70 cal temperature range, TTSL is a traditional thermosensitive liposome that triggers in the range of a

71 Bs) can improve tumor drug delivery from non-thermosensitive liposomes (NTSLs) and low temperature se

72 These polymer-modified thermosensitive liposomes (PTSL) demonstrated sensitivit

73 ocal drug delivery of Doxorubicin (Dox) with thermosensitive liposomes (TSL) and hyperthermia (HT) ha

74 Traditional thermosensitive liposomes are composed of lipids that un

75 a controlled manner, and when combined with thermosensitive liposomes can potentially reduce tumor b

76 Thermosensitive liposomes have emerged as a viable strat

77 vated levels of Mtg2p partially suppress the thermosensitive loss of mitochondrial DNA in a 21S rRNA

78 f an Escherichia coli fabD mutant encoding a thermosensitive malonyl coenzyme A-acyl carrier protein

79 itis elegans, this process is regulated by a thermosensitive membrane TRP channel and the DAF-16/FOXO

80 Surprisingly, a substantial number of thermosensitive mitral cells were also chemosensitive.

81 Strains carrying the thermosensitive mrsC505 allele stopped growing soon afte

82 ion) at the nonpermissive temperature in the thermosensitive mutant cell line tsBN2 caused nuclear ac

83 he four novel mutants, rad4-c17(TopBP1) is a thermosensitive mutant.

84 We have identified thermosensitive mutants of five Schizosaccharomyces pomb

85 FtsA*, FtsZL169R also can partially suppress thermosensitive mutants of ftsQ or ftsK, which encode ad

86 Spp1 is essential for cell viability, and thermosensitive mutants of spp1(+) exhibit an allele-spe

87 We generated a panel of fission yeast thermosensitive mutants of the B-subunit (termed Spb70)

88 Here, we use thermosensitive mutants to show that the replisome's pol

89 amined the effects of combining a well-known thermosensitive mutation of ftsZ, ftsZ84, with DeltaminC

90 Thermosensitive mutations in ftsA, such as ftsA27, map i

91 SNARE proteins on the vesicle docking step, thermosensitive mutations in Sed5p, Bet1p, Bos1p and Sly

92 Thermosensitive mutations of spp2(+) destabilize the Pol

93 Thermosensitive mutations were created in the mycobacter

94 ectrophysiological recordings, we identified thermosensitive neurons and examined their physiologic r

95 hat GABAA receptor induced inhibition of HDB thermosensitive neurons can modulate both thermoregulati

96 Drosophila larva are a set of exceptionally thermosensitive neurons critical for larval cool avoidan

97 Thermosensitive neurons of the preoptic/anterior hypotha

98 ition, a distinct anatomical distribution of thermosensitive neurons was found in the HDB.

99 demonstrate that the HDB contains inherently thermosensitive neurons, and that a difference in therma

100 d receptor-1 (VR1, also known as TRPV1) is a thermosensitive, nonselective cation channel that is exp

101 s C, isolates could be grouped into either a thermosensitive or thermostable fraction for both egg- a

102 tion delayed virus maturation and produced a thermosensitive particle.

103 The QD-containing thermosensitive particles were assembled with protein mo

104 The thermosensitive pathway requires cGMP-gated channels in

105 combination of distinct mechanosensitive and thermosensitive pathways.

106 ral wild-type backgrounds conferred a strong thermosensitive phenotype but partially rescued ydj1-151

107 ess Gre mutants are unable to complement the thermosensitive phenotype of GreA(-):GreB(-) E. coli str

108 isruption of CNGCb or CNGC2 produced a hyper-thermosensitive phenotype, giving rise to an HSR and acq

109 unctional copy of the pgsA gene carried on a thermosensitive plasmid.

110 tion rate of rad2Delta was also reduced in a thermosensitive polymerase background, but not in a liga

111 Thermosensitive polymeric delivery system (PLA-PEG-PLA)

112 san-zinc-insulin complex incorporated in the thermosensitive polymeric delivery system can be used as

113 he combination of RNA nanoparticles with the thermosensitive polymers increased the retention of the

114 known as poloxamers) are typical examples of thermosensitive polymers, but their use in drug delivery

115 Gametogenesis is a thermosensitive process in numerous metazoans, ranging f

116 cules in such a way that they retained their thermosensitive properties, including the completely rev

117 imed at rescuing the defects of a yeast Rpt6 thermosensitive proteasome mutant, we identified a prote

118 e lower critical solution temperature of the thermosensitive PVCL polymer.

119 in sensory neurons--suggest the existence of thermosensitive receptors distinct from VR1.

120 dynamic stability and dynamics that suggests thermosensitive regions in the fold that could initiate

121 The deletion mutation rates of all the thermosensitive replication mutators decreased in a rad2

122 Both UV-induced DNA damage and thermosensitive replication proteins have been used in m

123 truncated from both ends was cloned into the thermosensitive replicon pVE6007 and used to inactivate

124 When expressed in the thermosensitive S. cerevisiae ero1-1 strain, both eroA a

125 Thermosensitive sec12 and sec16 mutations caused a colla

126 Incubation of cells with thermosensitive Sec17-1p at nonpermissive temperature ca

127 ess lacZ (beta-galactosidase gene), into the thermosensitive shuttle replicon pG+host4 and assayed fo

128 y(organophosphazenes) (I-5), a hydrogel with thermosensitive sol-gel transition behavior, almost comp

129 le poly(organophosphazenes), a hydrogel with thermosensitive sol-gel transition behavior, almost comp

130 We show that a thermosensitive splicing event in the 3' untranslated re

131 conserved catalytic residues are viable but thermosensitive, suggesting that SAPHIRE has both an imp

132 ogen bonding is utilized to yield the highly thermosensitive supramolecular polymeric materials.

133 ns, the double mutant was significantly more thermosensitive than the ftsZ84 single mutant.

134 Both mutant proteins were more thermosensitive than the wild-type protein, but AdhE(A26

135 h enables robust activation of neurons using thermosensitive transient receptor potential (TRP) catio

136 isms are a large family of proteins known as thermosensitive transient receptor potential (TRP) ion c

137 Several thermosensitive transient receptor potential channels (t

138 the cloning and characterization of a novel thermosensitive TRP channel.

139 nsic temperature sensitivity common to other thermosensitive TRP channels.

140 We were unable to confirm the presence of thermosensitive TRPV1 and TRPM8 that has previously been

141 ole for the TRPV6-ARD than in the paralogous thermosensitive TRPV1 channel.

142 vanilloid (TRPV) channels, which include the thermosensitive TRPV1-V4, have large cytoplasmic regions

143 f the mutations (R321A and D425A) elicited a thermosensitive (ts) yeast growth phenotype.

144 The thermosensitive vector pTV1-OK harboring Tn917 was used

145 lum (ER) of living cells, we made use of the thermosensitive vesicular stomatitis virus tsO45 glycopr

146 The attachment of the thermosensitive VSVGtsO45 lumenal domain to proteins pro

147 ing a mixture of depletants, one of which is thermosensitive, we induce solid-to-solid phase transiti

148 Previous studies of thermosensitive yeast COPI mutants yielded the surprisin

149 74W-A as a novel multicopy suppressor of the thermosensitive yip1-4 strain.