ライフサイエンスコーパス: thermosensory

1 These studies imply that thermosensory activity coupled to serotonergic signaling

2 Disruption of thermosensory and pain integration may account for the c

3 demonstrate that an individual DAG-dependent thermosensory behavior of an organism is effected specif

4 functions in a neural network that regulates thermosensory behavior.

5 nderlying experience-dependent plasticity in thermosensory behavior.

6 he downstream effector for DAG regulation of thermosensory behavior.

7 f tax-6 and that it acts in the formation of thermosensory behavioral memory in C. elegans.

8 TRP) family of cation channels contribute to thermosensory behaviors in animals from flies to humans.

9 The AFD sensory neurons are essential for thermosensory behaviors, but the molecular mechanisms by

10 t cell autonomously to regulate AFD-mediated thermosensory behaviors.

11 migration in vitro and in wound healing and thermosensory behaviours in vivo.

12 nstrate that keratinocytes can indeed act as thermosensory cells and that they do so via at least two

13 . sensory innervation and trafficking of the thermosensory channel TRPV1 and the mechanosensory chann

14 tion of developmental mechanisms between the thermosensory circuit in C. elegans and the vertebrate p

15 urons are newly identified components of the thermosensory circuit, and that different combinations o

16 can identify much of the previously reported thermosensory circuitry as well as identify several unre

17 he finger cell neurons (AFD) are the primary thermosensory class in H. contortus.

18 itize TRPV1-expressing afferents revealed no thermosensory consequences of TRPV2 absence.

19 OCHROME INTERACTING FACTOR 4 (PIF4)-mediated thermosensory growth and architecture adaptations are di

20 ificance, the molecular mechanisms that link thermosensory growth and defense responses are not known

21 This study reveals a molecular link between thermosensory growth and immunity in plants.

22 blue-light receptor CRYPTOCHROME2 (CRY2) in thermosensory growth responses.

23 al circuit in the rat POA that processes the thermosensory information and outputs thermoregulatory e

24 ng pathway, showing that ttx-3 specifies AIY thermosensory information processing of both motor and a

25 ow that H2A.Z-containing nucleosomes provide thermosensory information that is used to coordinate the

26 trace the connections that relay peripheral thermosensory information to higher brain centres, and s

27 erm plasticity, and the ability to transform thermosensory input into different patterns of motor out

28 sions on the basis of temporal variations in thermosensory input, thereby augmenting the likelihood o

29 hermotactic behavior and exhibit deregulated thermosensory inputs into a neuroendocrine signaling pat

30 ensitivity and dynamics of the conversion of thermosensory inputs into motor responses.

31 e-lock their calcium dynamics to oscillatory thermosensory inputs.

32 at reveals the central inhibition of pain by thermosensory integration.

33 r potential vanilloid subtype I (TRPV1) is a thermosensory ion channel that is also gated by chemical

34 tion of TRPA1 activity is critical: when the thermosensory isoform is expressed in chemosensors, flie

35 These data reveal a new type of thermosensory molecule and uncover a functional distinct

36 The short life span of thermosensory mutants at warm temperature is completely

37 Thermosensory mutations shorten life span by decreasing

38 innocuous cold transducer in nociceptive and thermosensory nerve endings.

39 ecular mechanism for physiological tuning of thermosensory nerve fibres.

40 eathes the NREs of 12 neurons, including the thermosensory neuron AFD.

41 sses, the gustatory neuron class ASE and the thermosensory neuron class AFD, from the nematode Caenor

42 protein, to quantify the activity of the AFD thermosensory neuron of individual worms freely navigati

43 hold of responsiveness (T *(AFD)) of the AFD thermosensory neuron pair to temperature stimuli.

44 ot cell-autonomous but rather depends on the thermosensory neuron, AFD, which senses ambient temperat

45 ts by monitoring the activity of this single thermosensory neuron.

46 cytoprotective response is regulated by the thermosensory neuronal circuitry of C. elegans.

47 d for temperature-evoked activity in the AFD thermosensory neurons (T*(AFD)) in C. elegans is set by

48 n be generated via different combinations of thermosensory neurons acting degenerately, and emphasize

49 By recording from the C. elegans thermosensory neurons AFD in vivo, we found that cooling

50 Our data suggest that thermosensory neurons affect life span at warm temperatu

51 omous control of chaperone expression by the thermosensory neurons allows C. elegans to respond diffe

52 ted as thermosensory neurons, but additional thermosensory neurons are also predicted to play a role

53 SI and the previously identified AFD and AWC thermosensory neurons are necessary and sufficient under

54 s underlying the development and function of thermosensory neurons are poorly understood.

55 Surprisingly, inhibiting the function of thermosensory neurons by mutation or laser ablation caus

56 , we study the physiological role of the AFD thermosensory neurons by quantifying intracellular calci

57 P (transient receptor potential) channels in thermosensory neurons detect a variable range of tempera

58 emperature variations carried out by the DOG thermosensory neurons emerges in distinct motor response

59 Thermosensory neurons enable the nematode to remember it

60 Excitation of the AFD thermosensory neurons enhances serotonin release.

61 Random optogenetic stimulation of the DOG thermosensory neurons evokes behavioral patterns that mi

62 ium and voltage imaging reveals that the DOG thermosensory neurons exhibit activity patterns with sen

63 We discover three thermosensory neurons in each dorsal organ ganglion (DOG

64 ent begins with the activation of peripheral thermosensory neurons innervating the body surface.

65 r (HSF1), we show that excitation of the AFD thermosensory neurons is sufficient to activate HSF1 in

66 se in Caenorhabditis elegans is regulated by thermosensory neurons led us to consider whether neurona

67 range, suggesting that neuromodulation among thermosensory neurons maintains coherence of behavioral

68 ponses, uncover unique functional classes of thermosensory neurons mediating heat and cold sensing, a

69 , the expression of IR93a and IR25a includes thermosensory neurons of the arista.

70 We show that thermosensory neurons play a regulatory role in the temp

71 utamine expansion-expressing animals with WT thermosensory neurons readily express protein aggregates

72 specific roles of these channels in central thermosensory neurons remain unclear.

73 ed immunity through ADF chemosensory and AFD thermosensory neurons that regulate longevity.

74 ated at the organismal level by a network of thermosensory neurons that senses elevated temperatures

75 ame PLC that leads to activation of TRPA1 in thermosensory neurons was also required in the TRPA1-exp

76 ilateral AFD neurons have been implicated as thermosensory neurons, but additional thermosensory neur

77 either pan-neuronally or specifically in AFD thermosensory neurons, converted wild-type worms to a pk

78 at is expressed in olfactory, gustatory, and thermosensory neurons, implicating this channel in multi

79 a key role in the control of immunity by AFD thermosensory neurons, it did not control longevity thro

80 s are post-synaptic to most chemosensory and thermosensory neurons, it is probable that these activit

81 However, when the putative thermosensory neurons, the finger cell neurons (AFD), we

82 The internal AC (anterior cell) thermosensory neurons, which express TRPA1, detect warm

83 og ttx-1 specifies the identities of the AFD thermosensory neurons.

84 C. elegans senses temperature using the AFD thermosensory neurons.

85 dult AIY interneuron pair, which connects to thermosensory neurons.

86 uitry as well as identify several unreported thermosensory neurons.

87 but not temperature sensitivity, of the AFD thermosensory neurons.

88 ession, morphology, and functions of the AFD thermosensory neurons.

89 using RNA from sorted AWB olfactory and AFD thermosensory neurons.

90 The ttx-3-dependent thermosensory pathway also couples to the temperature-mo

91 Here, we report a thermosensory pathway that triggers physiological heat-d

92 e integration of parallel mechanosensory and thermosensory pathways.

93 ring and nonshivering thermogenesis, whereas thermosensory perception and heat conservation were norm

94 nucleosomes performs a central role in plant thermosensory perception.

95 The thermosensory phenotype is recapitulated in Caenorhabdit

96 ing in vivo calcium imaging, we describe the thermosensory projection neurons selectively activated b

97 nd that multiple domains contribute to their thermosensory properties.

98 rly understood that involves mobilization of thermosensory receptors to the neuronal surface.

99 m, a region we now define as a major site of thermosensory representation.

100 We show that a bidirectional thermosensory response (increasing temperature raises an

101 By analyzing the thermosensory response of AFD dendrites severed from the

102 However, because AFD thermosensory responses appear to be similar at all exam

103 gans, because BBS mutants manifest deficient thermosensory responses at both physiological and nocice

104 cultivation temperature (T(c)) modulates the thermosensory responses exhibited by C. elegans on therm

105 e independent tuning of an animal's distinct thermosensory responses.

106 Identification of thermosensory rGCs in C. elegans provides insight into m

107 We describe a major thermosensory role for the phytochromes (red light recep

108 members of the TRPA subfamily have distinct thermosensory roles in Drosophila, and mammalian TRPA1 i

109 In contrast, thermosensory signal transduction, which also requires t

110 Caenorhabditis elegans and in particular for thermosensory signaling and behavior.

111 erved GPCRs that are required for initiating thermosensory signaling cascades.

112 es (19 degrees to 24 degrees C) depends on a thermosensory signaling pathway that includes a heterotr

113 by glutamatergically transmitting cutaneous thermosensory signals received from spinal somatosensory

114 proteins in the acquisition of mechano- and thermosensory stimuli and highlight potentially clinical

115 We propose that this thermosensory system allows C. elegans to reduce the eff

116 of Caenorhabditis elegans indicate that its thermosensory system exhibits exquisite temperature sens