ライフサイエンスコーパス: thermotolerance

1 o protect cells from severe stress (acquired thermotolerance).

2 me facultative symbionts directly alter host thermotolerance.

3 f mtl-1 and hsp-70 promotes biofilm-mediated thermotolerance.

4 Htg6.1) from UC96US23 conferring germination thermotolerance.

5 late these genes nor does it further enhance thermotolerance.

6 dity and silencing Hsp70 reduced JGM-induced thermotolerance.

7 e thermally activated, resulting in enhanced thermotolerance.

8 a pivotal role in the response to ABA and in thermotolerance.

9 vated temperatures and defective in acquired thermotolerance.

10 Flies with Hsp70 deletions have reduced thermotolerance.

11 ability during heat shock and lower acquired thermotolerance.

12 otolerance, it is not essential for acquired thermotolerance.

13 but had a greatly reduced ability to promote thermotolerance.

14 ortant role for HsfA2 in regulating acquired thermotolerance.

15 a role in mediating the effects of acquired thermotolerance.

16 P70) synthesis and blocks the development of thermotolerance.

17 a chaperone function of an sHSP in cellular thermotolerance.

18 ved thermotolerance, whereas alkanes reduced thermotolerance.

19 vasation, indicating development of vascular thermotolerance.

20 velop lettuce lines that exhibit germination thermotolerance.

21 ce, and hot1 seeds had greatly reduced basal thermotolerance.

22 ion of these kinases did not reduce acquired thermotolerance.

23 y for JNK downregulation and is critical for thermotolerance.

24 t the hypothesis that isoprene enhances leaf thermotolerance.

25 at DnaJ plays an important role in C. jejuni thermotolerance.

26 an RpoS-dependent role in starvation-induced thermotolerance.

27 r ER molecular chaperones and thereby induce thermotolerance.

28 the proteasome inhibitors might also confer thermotolerance.

29 perature whereas a ypuN mutant has increased thermotolerance.

30 roxide dismutase genes caused an increase in thermotolerance.

31 els of Hsp1O4 are sufficient to provide full thermotolerance.

32 ting Hsp1O4 plays a critical role in induced thermotolerance.

33 ons caused a 500- to 20,000-fold increase in thermotolerance.

34 tress response which allows cells to acquire thermotolerance.

35 the induction of Hsps does not block induced thermotolerance.

36 uption is an important component of vascular thermotolerance.

37 ssolves heat-induced aggregates and promotes thermotolerance.

38 consistent with the development of vascular thermotolerance.

39 acclimation to evolve separately from basal thermotolerance.

40 49220) that both consistently showed reduced thermotolerance.

41 , particularly in assays of diet breadth and thermotolerance.

42 or NAC019 in Arabidopsis thaliana increases thermotolerance.

43 s essential to establish short-term acquired thermotolerance.

44 xhibit severely impaired HSR and compromised thermotolerance.

45 terial cells instead of improvement of their thermotolerance.

46 HSF-FoxM1 connection that mediates cellular thermotolerance.

47 n regulating thermotolerance and in acquired thermotolerance.

48 tol-sensitive mechanisms that enhance Q-cell thermotolerance.

49 inolytic peptidase B chaperonin required for thermotolerance.

50 heat-challenged adults, suggesting a role in thermotolerance.

51 , such as pathogen defense, development, and thermotolerance.

52 HSR, leading to the onset of plant acquired thermotolerance.

53 is an equatorial perennial with a high basal thermotolerance.

54 n vivo and in vitro, as well as for cellular thermotolerance.

55 ere heat shock, a phenomenon called splicing thermotolerance.

56 sh1 recA3 double mutants exhibiting enhanced thermotolerance.

57 romie et al., also confers similar increased thermotolerance.

58 teins and are molecular machines involved in thermotolerance.

59 for panA knockouts, which displayed enhanced thermotolerance.

60 NO-overproducing mutant is also defective in thermotolerance.

61 r the A. thaliana FtsH11-encoded protease in thermotolerance, a function previously reported for bact

62 on tests showed that HSFA6b was required for thermotolerance acquisition.

63 ensitive mutants (atts) that fail to acquire thermotolerance after pre-conditioning at 38 degrees C.

64 s in many organisms correlates with enhanced thermotolerance, altered growth, and development.

65 Both basal thermotolerance and acclimation are thought to be import

66 lenging for ectotherms, which use both basal thermotolerance and acclimation, an adaptive plastic res

67 lelic variants of SSD1 regulate the level of thermotolerance and cell wall remodeling.

68 mRNA and protein, which was associated with thermotolerance and cytoprotection from TNFalpha+actinom

69 We tested thermotolerance and expression of pathogenesis-related (

70 MBF1c is required for thermotolerance and functions upstream to SA, trehalose,

71 hromatin regulation play roles in regulating thermotolerance and in acquired thermotolerance.

72 esulted in deficient maintenance of acquired thermotolerance and increased sensitivity to heat stress

73 with the purity required to study plant cell thermotolerance and its relationship to plant cell survi

74 that the mechanisms by which H(2)S increases thermotolerance and lifespan in nematodes are conserved

75 bunit IV in LACK-deficient L. major restored thermotolerance and macrophage infectivity.

76 on of JNK is therefore critical for acquired thermotolerance and may play a role in tolerance to othe

77 a novel stress response protein required for thermotolerance and mitigation of oxidative stress-induc

78 Osmotic stress is known to increase the thermotolerance and oxidative-stress resistance of bacte

79 signalling is required for differentiation, thermotolerance and pathogenesis in C. neoformans.

80 These variants were tested for both improved thermotolerance and performance in the bioscouring appli

81 or thermotolerance, uncovers a role of NO in thermotolerance and plant development.

82 nstrate that BOB1 is required for organismal thermotolerance and postembryonic development.

83 To determine P. sulfincola thermotolerance and preference, we developed a high-pres

84 upported [PSI(+)] and functioned normally in thermotolerance and protein disaggregation.

85 nterestingly, pals-22 mutants have increased thermotolerance and reduced levels of stress-induced pol

86 tes dramatically during heat shock, enhances thermotolerance and reduces aggregation of denatured pro

87 stationary phase in many organisms, enhances thermotolerance and reduces aggregation of denatured pro

88 cylic acid pathways are involved in acquired thermotolerance and that UVH6 plays a significant role i

89 ellular processes, namely the acquisition of thermotolerance and the refolding of thermally denatured

90 l signaling mechanisms that lead to acquired thermotolerance and thermoinhibition.

91 ation of protein aggregates is essential for thermotolerance and to facilitate the maintenance of pri

92 nase (RACK1), that is important for parasite thermotolerance and virulence.

93 oreover, we demonstrate that Ydj1p-dependent thermotolerance and Ydj1p localization are perturbed whe

94 phenotype in two assays of Hsp104 function (thermotolerance and yeast prion propagation), demonstrat

95 C), which is critical for the acquisition of thermotolerance, and At1g74320 encodes for choline kinas

96 Research on biology, host range and shifts, thermotolerance, and demography has provided useful info

97 d hot1 seedlings were also unable to acquire thermotolerance, and hot1 seeds had greatly reduced basa

98 ed to increased ESRE transcription, enhanced thermotolerance, and induction of a nuclear ESRE-binding

99 f pat-10 increased actin filament stability, thermotolerance, and longevity, indicating that in addit

100 1 contribute to optimum growth, development, thermotolerance, and regulation of the heat shock respon

101 l CP-sHSP isoforms was genetically linked to thermotolerance, and that the presence of the additional

102 abscisic acid (ABA) is involved in acquired thermotolerance as well.

103 In thermotolerance assays hot1-3 shows a similar, though so

104 Thermotolerance assays of PME gene T-DNA insertion lines

105 Measurement of thermotolerance at different growth stages reveals that

106 enic line were tested for basal and acquired thermotolerance at different stages of growth.

107 henotype, giving rise to an HSR and acquired thermotolerance at significantly milder heat-priming tre

108 0-day-old seedlings, and it is wild type for thermotolerance at these stages.

109 Acquired thermotolerance (AT) is the ability of cells to survive

110 dine lactam inhibitor of hsp70 induction and thermotolerance, attenuated 17-AAG-mediated hsp70 induct

111 r heat stress-responsive gene regulation and thermotolerance, because, compared with the wild type, t

112 ogether had synergistic effects in promoting thermotolerance but did not increase hsp expression beyo

113 een significantly increased exhibit improved thermotolerance but display no detectable difference in

114 eat-shock protein (Hsp) is involved in plant thermotolerance but its site of action is unknown.

115 en a genetic approach to dissecting acquired thermotolerance by characterizing loss-of-function therm

116 tudy not only suggests that AtPARK13 confers thermotolerance by degrading misfolded protein targets,

117 It has been suggested that isoprene improves thermotolerance by helping photosynthesis cope with high

118 Hsp100/ClpB chaperone (AtHsp101) in acquired thermotolerance by isolating recessive, loss-of-function

119 an Arabidopsis line engineered for increased thermotolerance by overexpressing the cytosolic isoform

120 increased Mg(2+) accumulation might enhance thermotolerance by protecting the integrity of proteins

121 to Hsf1 activation and subsequently induced thermotolerance by thiol-reactive compounds, but not by

122 Potential thermotolerance candidate loci contained within our QTL

123 genes critical for cognition, olfaction, and thermotolerance, consistent with the observed patterns o

124 the reversible inhibitor MG132 was removed, thermotolerance decreased rapidly, while synthesis of hs

125 In addition to exhibiting a thermotolerance defect as assayed by hypocotyl elongatio

126 s and its expression in yeast complemented a thermotolerance defect caused by a deletion of the HSP10

127 Mutants were assessed for thermotolerance defects in seed germination, hypocotyl e

128 In addition to thermotolerance defects, bob1-3 exhibits pleiotropic dev

129 was performed to define the nature of their thermotolerance defects.

130 ly resistant to guanidine, and the degree of thermotolerance did not correlate with [PSI(+)] stabilit

131 Although thermotolerance did not correlate with hsp content, anot

132 ce, consistent with the observed patterns of thermotolerance differences and assortative mating.

133 ently involved an NPR1-dependent pathway but thermotolerance during HS did not.

134 for the priming process that sustains pollen thermotolerance during microsporogenesis.

135 SA promoted thermotolerance during the HS itself and subsequent reco

136 previously unrecognized strategy to achieve thermotolerance, especially for the protection of reprod

137 ) were more defective in basal than acquired thermotolerance, especially under high light.

138 on/repair pathway for denatured proteins and thermotolerance expression in vivo.

139 Hsp70 is a broadly conserved thermotolerance factor, but inhibits growth at normal te

140 NBD) of Hsp104 (NBD1 and NBD2) eliminate its thermotolerance function in vivo.

141 t is not toxic but specifically inhibits the thermotolerance function of WT Hsp104.

142 ells subject to nutrient limitation, but its thermotolerance function remained unaffected.

143 8 degrees C sensitivity, but did not restore thermotolerance function to hot1-4, and Class 2 suppress

144 d Class 2 suppressors that restored acquired thermotolerance function to hot1-4.

145 hock protein that has both developmental and thermotolerance functions and may play a role in both of

146 contribution to this phenotype or that other thermotolerance genes encode essential or redundant func

147 However, the evidence for the thermotolerance hypothesis is indirect and one of three

148 ed in processes predicted to be required for thermotolerance (i.e. protection of proteins and of tran

149 evidence for SA-dependent signaling in basal thermotolerance (i.e. tolerance of HS without prior heat

150 in bacteria and yeast, is also essential for thermotolerance in a complex eukaryote.

151 show that elevated levels of AtPARK13 confer thermotolerance in A. thaliana.

152 lipid metabolism and TAG formation increases thermotolerance in addition to the genetically encoded H

153 nhibition of DDL-1/2 increases longevity and thermotolerance in an hsf-1-dependent manner.

154 n bridging factor 1c), is a key regulator of thermotolerance in Arabidopsis thaliana.

155 at BABA also significantly enhances acquired thermotolerance in Arabidopsis.

156 r heat stress-responsive gene expression and thermotolerance in Arabidopsis.

157 ic analysis showed that the loss of acquired thermotolerance in AtTS02 was a recessive trait.

158 evidence that Hsp101, which is required for thermotolerance in bacteria and yeast, is also essential

159 t exposure to H2S increases the lifespan and thermotolerance in Caenorhabditis elegans, and improves

160 e and secondary metabolites ingrained higher thermotolerance in cv. Unnat Halna, among others.

161 okaryotic homolog of Hsp90, is essential for thermotolerance in cyanobacteria, and in vitro it suppre

162 ppears to be a major contributor to acquired thermotolerance in mammalian cells.

163 vides an excellent prospect for manipulating thermotolerance in other species.

164 associated with the concomitant induction of thermotolerance in PDT-treated cells.

165 nscription factors play an important role in thermotolerance in plants and other organisms, controlli

166 rone that is required for the development of thermotolerance in plants and other organisms.

167 protein101 (HSP101) is required for acquired thermotolerance in plants and other organisms.

168 ast ortholog, Hsp104, are required to confer thermotolerance in plants and yeast (Saccharomyces cerev

169 ere recently shown to play a central role in thermotolerance in plants, a key regulator of these resp

170 To identify the various mechanisms of thermotolerance in plants, we isolated a series of Arabi

171 -generated stress signal that enhances basal thermotolerance in plants.

172 cs associated with the induction of acquired thermotolerance in response to heat shock and acquired f

173 In a genetic analysis of the determinants of thermotolerance in S. enterica serovar Typhimurium, we i

174 CA) cycle metabolite, increased lifespan and thermotolerance in the nematode C. elegans.

175 ost and its expression resulted in increased thermotolerance in tobacco.

176 lar functions, including endowing cells with thermotolerance in vivo and being able to act as molecul

177 educed the ability of the protein to provide thermotolerance in vivo.

178 Hsp104 disaggregase provides thermotolerance in yeast by recovering proteins from agg

179 ind ClpB supports both prion propagation and thermotolerance in yeast if it is modified to interact w

180 Our findings show prion propagation and thermotolerance in yeast minimally require cooperation o

181 ibutions in acquired cellular resistance or "thermotolerance" in mammalian cells is presently unknown

182 dependent of Hsp synthesis, are required for thermotolerance, including protection of membrane integr

183 xidative damage is the likely cause of shot1 thermotolerance, indicating HSP101 repairs protein oxida

184 Acquired thermotolerance is a complex physiological phenomenon th

185 Our data thus provide evidence that splicing thermotolerance is acquired through maintenance of SRSF1

186 itive to heat stress and because the reduced thermotolerance is correlated with lower expression of m

187 A(+)) mRNA accumulation upon heat shock, and thermotolerance is decreased in a nup42 nab2-T178A/S180A

188 Acquisition of thermotolerance is likely to be of particular importance

189 nteraction analysis that the role of Tps1 in thermotolerance is not dependent upon Hsf1-dependent tra

190 Although SA promotes basal thermotolerance, it is not essential for acquired thermo

191 ult longevity (Age), and increased intrinsic thermotolerance (Itt).

192 mperature incubation step, and the resulting thermotolerance landscape allowed the discovery of mutat

193 We argue that acquisition of thermotolerance may represent a positive selection for t

194 d for the extension of lifespan and enhanced thermotolerance mediated by extra copies of the deacetyl

195 tolerance by characterizing loss-of-function thermotolerance mutants in Arabidopsis.

196 cribes a procedure for selection of acquired thermotolerance mutants, and provides the physiological

197 The thermotolerance of anaerobically grown cells is not due

198 Thermotolerance of cells expressing mutant proteins was

199 The thermotolerance of cells in anaerobic conditions was imm

200 established role for ethylene in germination thermotolerance of Compositae seeds.

201 tenfold reduced level, resulting in reduced thermotolerance of germinating seeds and underscoring th

202 re a substantial and durable increase in the thermotolerance of hybrid poplar (Populus tremulaxPopulu

203 recessive alleles of four loci required for thermotolerance of hypocotyl elongation, hot1-1, hot2-1,

204 Thermotolerance of luciferase activity and of ion leakag

205 It is concluded that thermotolerance of photosynthesis is a substantial benef

206 is an important mechanism for improving the thermotolerance of plant photosystems as temperatures in

207 ce that leaf-internal isoprene increases the thermotolerance of plants and protects them against oxid

208 h6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival.

209 otein of Bacillus subtilis also enhanced the thermotolerance of S. enterica.

210 hanism by which high osmolality enhances the thermotolerance of Salmonella enterica serovar Typhimuri

211 y high temperature and did not contribute to thermotolerance of seedlings.

212 Because thermotolerance of Synechocystis depends on HSP16.6, a p

213 However, the thermotolerance of the two species differs: while A. fum

214 Furthermore, this "thermotolerance" of SRSF10 phosphorylation, like that of

215 ression of SEC-1 in Escherichia coli confers thermotolerance on the bacterium.

216 arental lines, we mapped seven QTL affecting thermotolerance on the second and third chromosomes.

217 but insufficient is known about its role in thermotolerance or how this relates to SA signaling in p

218 lpha-decarboxylase had significantly greater thermotolerance (P<or=0.05) during germination.

219 otein level was correlated with the acquired thermotolerance phenotype.

220 in complex patterns of genetic variation in thermotolerance phenotypes in nature.

221 (Oregon-R and 2b) that were not selected for thermotolerance phenotypes, but exhibit significant gene

222 nderstand and identify the genes controlling thermotolerance phenotypes, we have used a mapping popul

223 These findings indicate that increased thermotolerance post-bleaching resulted from symbiont co

224 induction temperatures for maximum acquired thermotolerance prior to a high temperature challenge we

225 accumulation levels (our measure of acquired thermotolerance) ranging from 10% to 98% of control seed

226 JGM treatments led to increased thermotolerance, recorded as decreased mortality under h

227 ere directed primarily by Hsp40 Sis1p, while thermotolerance relied mainly on Hsp40 Ydj1p.

228 ock, indicating that a significant degree of thermotolerance remains in the absence of Hsp70.

229 ing cpr5 genotypes having lowest and highest thermotolerance, respectively.

230 s, such as mitochondrial protein maturation, thermotolerance, senescence, or enriched subcellular loc

231 L66A causes severe defects in thermotolerance, suggesting that oligomeric stability of

232 , mutants lacking components of the acquired thermotolerance system were isolated.

233 t mutants are the first mutants defective in thermotolerance that have been isolated in a higher euka

234 cumulate heat shock protein 70 and develop a thermotolerance that, upon transfer of cells to 32 degre

235 and were reduced in plants that had acquired thermotolerance through a mild heat pretreatment.

236 , by inference, sumoylation facilitate basal thermotolerance through processes that are SA independen

237 unusual in that it not only fails to develop thermotolerance to 45 degrees C after acclimation at 38

238 bidopsis thaliana that are unable to acquire thermotolerance to high-temperature stress and have defi

239 Plants acquire thermotolerance to lethal high temperatures if first exp

240 ed that HSFA1a/HSFA1b/HSFA1d are involved in thermotolerance to mild heat stress at temperatures as l

241 The ability of organisms to acquire thermotolerance to normally lethal high temperatures is

242 to hot temperatures), which is required for thermotolerance, uncovers a role of NO in thermotoleranc

243 BABA did not enhance basal thermotolerance under a severe heat-shock treatment.

244 phenotypic effects other than a decrease in thermotolerance under both photoautotrophic and photomix

245 Increased thermotolerance was also not observed in C3-dominated co

246 The role of ABA in BABA-induced thermotolerance was complex.

247 This thermotolerance was dependent on heat shock protein 101,

248 Thermotolerance was increased by proline or tryptophan s

249 n of HsfA2 in heat stress response (HSR) and thermotolerance was investigated in different tissues of

250 Development of thermotolerance was not associated with Akt or ERK1 and

251 In contrast, thermotolerance was not attainable in hsf1(-/-) cells, a

252 BABA-enhanced thermotolerance was partially compromised in the ABA-ins

253 A similar induction of hsps and thermotolerance was seen with another proteasome inhibit

254 ionally important for innate and/or acquired thermotolerance, we combined the use of a barcoded pool

255 tify molecular events important for acquired thermotolerance, we compared viability and transcript pr

256 interact with HSP101 or that are involved in thermotolerance, we screened for extragenic suppressors

257 expressed in hsf1-m3 cells is sufficient for thermotolerance, we used heterologous promoters to regul

258 and salicylic acid in BABA-induced acquired thermotolerance were identified by mutant analysis.

259 Estimates of heritability of larval thermotolerance were low, but significant, and all life-

260 Nineteen variants with further improved thermotolerance were produced.

261 , 36 single site mutants exhibiting improved thermotolerance were produced.

262 Predicted growth-limiting factors for thermotolerance were validated through nutrient suppleme

263 ch do not make isoprene, exhibited increased thermotolerance when isoprene was supplied in the airstr

264 Other short-chain alkenes also improved thermotolerance, whereas alkanes reduced thermotolerance

265 Endogenous SA correlated with basal thermotolerance, with the SA-deficient NahG and SA-accum

266 At 38 degrees C, GCP acquire thermotolerance within 24 h, but their expansion is limi