ライフサイエンスコーパス: thiamine

1 containing either thiamine pyrophosphate or thiamine.

2 all essential vitamins with the exception of thiamine.

3 hysiological concentrations of extracellular thiamine.

4 rsed at high extracellular concentrations of thiamine.

5 oxymethyl-2-methylpyrimidine (HMP) moiety of thiamine.

6 olished the biosynthesis of s(4)U but not of thiamine.

7 r the biosynthesis of 4-thiouridine, but not thiamine.

8 ification in tRNA and the thiazole moiety of thiamine.

9 selectively (turn on) after the addition of thiamine.

10 but when the SCTs bind, ThDP is modified to thiamine 2-thiazolone diphosphate.

11 Thiamine 200 mg or matching placebo twice daily for 7 da

12 In the case of the thiamine 5'-pyrophosphate (TPP) riboswitch from the Esch

13 rgy (74.1%, P = .04), iron (73.4%, P = .01), thiamine (74.0%, P = .00), and riboflavin (73.3%, P = .0

14 od, it was possible to relate the amounts of thiamine added in model cooked hams to the amounts of 2-

15 In the present work, we describe a new thiamine amperometric biosensor based on thiamine pyroph

16 mediate in the common pathway to purines and thiamine and is generated in bacteria by glutamine phosp

17 tection of 0.5 nM) and specific bioassay for thiamine and its phosphorylated derivatives can be desig

18 on of the sulfur transfer chemistry found in thiamine and molydobterin biosynthesis.

19 se, the mean +/- SD maximal concentration of thiamine and net area under the thiamine concentration-t

20 ls at 24 hours after study start between the thiamine and placebo groups (median: 2.5 mmol/L [1.5, 3.

21 The pivotal role of PUT3 mediated thiamine and polyamine homeostasis in plants, and its im

22 that PUT3 mediates phloem transport of both thiamine and polyamines.

23 alysis revealed remarkable concentrations of thiamine and pyridoxine in pistachios (57%, 79% of the r

24 attenuated among women with high intakes of thiamine and riboflavin (P < 0.05).

25 er risk of PMS in women with high intakes of thiamine and riboflavin from food sources only.

26 Intakes of thiamine and riboflavin from food sources were each inve

27 3 microM) concentration ranges, specific for thiamine and sensitive to sulfhydryl group inhibition.

28 Median Cambodian infant total plasma thiamine and TDP concentrations increased from 3.0 nmol/

29 deficient, with median (range) total plasma thiamine and TDP concentrations of 2.4 nmol/L (0-4.4 nmo

30 Day 6 median maternal total plasma thiamine and TDP concentrations were normal [18.6 nmol/L

31 rect link between the thermal degradation of thiamine and the formation of these compounds.

32 thylpyrimidine (HMP) pyrophosphate moiety of thiamine and the last intermediate in the common HMP/pur

33 ntial enzyme involved in the biosynthesis of thiamine and the tRNA thionucleoside modification, 4-thi

34 ntermediates and to enable plants to produce thiamine and thiamine pyrophosphate for growth and devel

35 was found that 5% (w/v) lactose, 0.1% (w/v) thiamine, and 0.1% (w/v) FeCl3 led to the maximal produc

36 rdiac metabolism: coenzyme Q10, l-carnitine, thiamine, and amino acids, including taurine.

37 of inorganic nitrogen, inorganic sulfur, and thiamine, and genes encoding carbohydrate active enzymes

38 magnesium; in the LEARN group for vitamin E, thiamine, and magnesium; and in the Ornish group for vit

39 les was experimentally confirmed for folate, thiamine, and riboflavin transporters.

40 micronutrients and vitamins, such as biotin, thiamine, and riboflavin.

41 hiamin pyrophosphate-dependent enzymes using thiamine antagonists - amprolium (AM), oxythiamine (OT)

42 ), lipoic acid, pectin, epigallocatechin and thiamine are also effective for Hg(II).

43 Sensory analyses highlighted the role of thiamine as a precursor of cooked ham aroma.

44 nalysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenz

45 supplementation, suggesting that blk1-R is a thiamine auxotroph.

46 Implications for thiamine-based enzymes are discussed.

47 n (CaM) and thiamine monophosphate (ThMP) to thiamine binding protein A (TbpA).

48 hyorhinis p37, renamed the extracytoplasmic thiamine-binding lipoprotein (Cypl).

49 Genes encoding high-affinity folate- and thiamine-binding proteins (FolT, ThiT) were identified i

50 ifferent species of mycoplasma show that the thiamine-binding site is likely conserved and structural

51 ding protein (TBP) from Escherichia coli for thiamine biorecognition and dye-encapsulating liposomes

52 nella enterica, sulfur is trafficked to both thiamine biosynthesis and 4-thiouridine biosynthesis by

53 ular thiamine concentration due to increased thiamine biosynthesis and transport, implicating NAD(+)

54 the analysis of several mutants defective in thiamine biosynthesis and was implicated as having a rol

55 and K96243 that are deficient in adenine and thiamine biosynthesis but replication competent in vitro

56 Genes encoding thiamine biosynthesis enzymes in microorganisms are tigh

57 Sequences with similarity to thiamine biosynthesis enzymes that are lacking in the ge

58 in purine biosynthesis and also required for thiamine biosynthesis in Salmonella enterica.

59 elevance of AphA and AnsB in contributing to thiamine biosynthesis in vivo is discussed.

60 ear-complete de novo pyrimidine, purine, and thiamine biosynthesis pathways and is unique amongst stu

61 argely unbiased in vivo approach centered on thiamine biosynthesis to identify new metabolic componen

62 nnections between cofactors biosynthesis and thiamine biosynthesis, and how metabolites from one bios

63 ily was previously thought to be involved in thiamine biosynthesis, but our characterization of TP079

64 enzyme that catalyses thiazole formation in thiamine biosynthesis.

65 ion in vivo, they cluster in chlorophyll and thiamine biosynthesis.

66 organisms that lack ThiI but are capable of thiamine biosynthesis.

67 IR), a branch point metabolite of purine and thiamine biosynthesis.

68 from one biosynthetic pathway can be used in thiamine biosynthesis.

69 scU for FeS cluster biogenesis, and ThiI for thiamine biosynthesis/tRNA thiolation), which bind at di

70 in a highly conserved amino acid encoded by thiamine biosynthesis2 (thi2).

71 hanisms exist to generate PRA sufficient for thiamine but not purine synthesis.

72 Roasting had a diminishing effect on thiamine, carotenoids and tocopherols especially in almo

73 Secondary outcomes, breast milk thiamine concentration and infant eTDP, were measured at

74 Sum1 HDAC complex elevated the intracellular thiamine concentration due to increased thiamine biosynt

75 Median Cambodian total breast milk thiamine concentration increased from 180 nmol/L (85-359

76 ne exhibits a linear relationship within the thiamine concentration range of 10-50 muM.

77 entration of thiamine and net area under the thiamine concentration-time curve were 73.4 +/- 45.6 nmo

78 ightly regulated such that low environmental thiamine concentrations activate transcription and high

79 ly lactation had higher eTDP and breast milk thiamine concentrations and their infants had higher eTD

80 n and newborn infants and higher breast milk thiamine concentrations compared with a control sauce.

81 Breast milk total thiamine concentrations were 14.4 mug/dL for the control

82 hiamine, with sharp increases in breast milk thiamine concentrations, but their breastfed infants rem

83 maternal thiamine intake reduces breast milk thiamine concentrations, placing breastfed infants at ri

84 ygotes (T/T) displayed decreased erythrocyte thiamine content on microbiological assay.

85 aracterization of 79 patients with inherited thiamine defects causing encephalopathy in childhood, id

86 Undiagnosed and untreated thiamine deficiencies are often fatal or lead to severe

87 Using the pyrithiamine-induced thiamine deficiency (PTD) animal paradigm of WKS, our la

88 In the pyrithiamine-induced thiamine deficiency (PTD) rat model of WKS, there are si

89 Pyrithiamine-induced thiamine deficiency (PTD) was used to produce a rodent m

90 f diencephalic amnesia, pyrithiamine-induced thiamine deficiency (PTD), was used to investigate dienc

91 occur during the acute and chronic phases of thiamine deficiency and describe how rodent models of We

92 mical and cognitive deficits associated with thiamine deficiency as well as proven useful toward grea

93 ley rats were assigned to one of 4 stages of thiamine deficiency based on behavioral symptoms: pre-sy

94 ignificantly, these results demonstrate that thiamine deficiency causes selective cholinergic dysfunc

95 Primary and secondary conditions leading to thiamine deficiency have overlapping features in childre

96 Rodent models of thiamine deficiency have yielded significant insight int

97 ent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes.

98 supplementation may be necessary to correct thiamine deficiency in breastfed infants.

99 It is unlikely that the thiamine deficiency is caused by impaired phosphorylatio

100 Thiamine deficiency is common in parts of Asia and cause

101 effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and

102 cofactors, particularly a low-protein diet, thiamine deficiency, alcoholism, and hypothyroidism.

103 extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterati

104 iovascular traits previously associated with thiamine deficiency, including elevated cardiac stroke v

105 In those with baseline thiamine deficiency, patients in the thiamine group had

106 iberi, a potentially fatal disease caused by thiamine deficiency, remains a public health concern in

107 lsive status epilepticus, endocrinopathy, or thiamine deficiency.

108 trations, but their breastfed infants remain thiamine deficient after 5 d of maternal supplementation

109 35% of the patients were thiamine deficient at baseline.

110 On day 1, Cambodian mothers were thiamine deficient, with median (range) total plasma thi

111 Thiamine-deficient Cambodian mothers effectively absorb

112 The thiamine-dependent E1o component (EC 1.2.4.2) of the 2-o

113 amount of holoenzyme and apoenzyme forms of thiamine-dependent enzymes, revealed episodically occurr

114 retion of organic acids that are specific of thiamine-dependent mitochondrial enzymes, mainly lactate

115 in comparison with glucose, fructose induces thiamine-dependent transketolase flux and is preferentia

116 iamine metabolite, and benfotiamine, another thiamine derivative, did not interfere with the effect o

117 Food and Drug Administration (FDA)-approved thiamine derivative.

118 Administration of thiamine did not improve lactate levels or other outcome

119 Total plasma thiamine, whole-blood thiamine diphosphate (TDP), and breast milk total thiami

120 The thiamine diphosphate (ThDP) and metal-ion-dependent enzy

121 y also show that when these herbicides bind, thiamine diphosphate (ThDP) is modified.

122 ivesite mechanism occurs during catalysis in thiamine diphosphate (ThDP)-dependent enzymes.

123 onversion of thiamine triphosphate (ThTP) to thiamine diphosphate and has an absolute requirement for

124 This reaction is catalyzed by the thiamine diphosphate and metal-ion-dependent 2-succinyl-

125 es reveal the characteristic fold that binds thiamine diphosphate and resemble closely the alpha(2)be

126 Pyruvate decarboxylase (PDC) uses thiamine diphosphate as an essential cofactor to catalyz

127 rtified fish sauce yields higher erythrocyte thiamine diphosphate concentrations (eTDP) among lactati

128 The catalytic cofactor thiamine diphosphate is found in many enzymes of central

129 Thiamine diphosphate is required as a cofactor in at lea

130 the structure of the holo form indicates how thiamine diphosphate organizes the active site pocket of

131 alidated by the determination of KD(app) for thiamine diphosphate, the TK cofactor and the inhibition

132 e of an oxygen-dependent free radical in the thiamine diphosphate-dependent Escherichia coli 2-oxoglu

133 dehyde 3-phosphate (D-GAP) and pyruvate in a thiamine diphosphate-dependent manner.

134 nto the role of metabolic cofactors, such as thiamine, during the proliferation of stem and initial c

135 ng the first day of admission: 200-500 mg IV thiamine every 8 hours, 64 mg/kg magnesium sulfate (appr

136 u(2+) ion modified C-dots in the presence of thiamine exhibits a linear relationship within the thiam

137 nadequacy (P < 0.05) in the Atkins group for thiamine, folic acid, vitamin C, iron, and magnesium; in

138 Thiamine-fortified fish sauce has the potential to preve

139 men in the control group, women who consumed thiamine-fortified fish sauce through pregnancy and earl

140 Objective: To determine if consumption of thiamine-fortified fish sauce yields higher erythrocyte

141 vo biosynthesis pathways or uptake exogenous thiamine from the environment via specific transporters.

142 aseline thiamine deficiency, patients in the thiamine group had significantly lower lactate levels at

143 also been carried out in 1.0x10(-4)molkg(-1) thiamine HCl and pyridoxine HCl solutions.

144 hols in (0.05, 0.15, 0.25 and 0.35)molkg(-1) thiamine HCl(aq) and pyridoxine HCl(aq) solutions over t

145 he complex regulatory mechanisms maintaining thiamine homeostasis in plants.

146 absorbable and could contribute toward host thiamine homeostasis, especially toward cellular nutriti

147 ant feedback between p53 transactivation and thiamine homeostasis.

148 nsport, implicating NAD(+) in the control of thiamine homeostasis.

149 fants before and after mothers received oral thiamine hydrochloride (100 mg for 5 d).

150 re and characterize nanoliposomes containing thiamine hydrochloride and study their physicochemical s

151 specialized and regulated uptake process for thiamine in a cellular model of human retinal pigment ep

152 eveloped was applied to the determination of thiamine in certified reference material (BCR-485), phar

153 Pharmacokinetics of thiamine in deficient populations are unknown.

154 riments is that raising the plasma levels of thiamine in FeLV-infected cats may ameliorate the pathog

155 The detection of thiamine in human body is very important to prevent vari

156 esults point towards insufficient amounts of thiamine in the food.

157 crobiota synthesize a considerable amount of thiamine in the form of thiamine pyrophosphate (TPP).

158 t strain could grow independent of exogenous thiamine in the presence of cysteine, suggesting there w

159 s strong a recommendation as for prescribing thiamine in this setting.

160 se in mortality over time in those receiving thiamine in this subgroup (p = 0.047).

161 y (AdSV), for determination of vitamin B(1) (thiamine) in pharmaceutical preparation and food is desc

162 closely intercorrelated way when the dose of thiamine increases.

163 ion for the presence of a thiazolium ring in thiamine instead of the otherwise generally more availab

164 Low maternal thiamine intake reduces breast milk thiamine concentrati

165 amino acids, sodium and potassium chloride, thiamine, iron, zinc, magnesium, hypoxanthine, and pyruv

166 rupt thiamine uptake into cells and, because thiamine is an essential nutrient, whether this disrupti

167 oxymethyl-2-methylpyrimidine (HMP) moiety of thiamine is synthesized from 5-aminoimidazole ribotide (

168 Of these deficiencies, thiamine is the most important for the practicing clinic

169 Thiamine levels in the seeds and cotyledons were lower i

170 y to achieve sufficiently high intracellular thiamine levels.

171 sauce consumption for 6 months: control (no thiamine), low-concentration (2 g/L), or high-concentrat

172 ress often associated with the impairment in thiamine metabolism and its functions.

173 Using thiamine metabolism as an example, we also show that app

174 Impairment in thiamine metabolism can be induced experimentally via in

175 of folate metabolism, the down-regulation of thiamine metabolism, and tight regulation of oxidative p

176 Since Breslow's initial report on the thiamine mode of action, the study of catalytic acyl car

177 Thiamine monophosphatase (TMPase, also known as fluoride

178 he binding of Ca(2+) to calmodulin (CaM) and thiamine monophosphate (ThMP) to thiamine binding protei

179 c for TPP and not affected by free thiamine, thiamine monophosphate, or choline.

180 A thiamine monosuccinate-PEG-biotin derivative was synthes

181 Addition of thiamine or cysteine also enabled us to study the effect

182 overexpressing plants were supplemented with thiamine or thiamine pyrophosphate throughout the life c

183 ciated with poor intake of energy (P = .04), thiamine (P = .02), and riboflavin (P = .01).The proport

184 The high-throughput method relies upon the thiamine periplasmic binding protein (TBP) from Escheric

185 We characterized thiamine pharmacokinetics in Cambodian mothers and their

186 This study shows that thiamine plays a major role in the formation of three ke

187 Similar to thiamine, polyamines are an essential set of charged mol

188 health concern in Cambodia and regions where thiamine-poor white rice is a staple food.

189 Strains lacking yjgF synthesize the thiamine precursor phosphoribosylamine (PRA) by a TrpD-d

190 thylpyrimidine phosphate, an intermediate of thiamine pyrophosphate (coenzyme B1) biosynthesis.

191 new thiamine amperometric biosensor based on thiamine pyrophosphate (ThDP)-dependent transketolase (T

192 The structure shows thiamine pyrophosphate (TPP) and two calcium ions are bo

193 We analyzed the structure of the native thiamine pyrophosphate (TPP) riboswitch aptamer domain a

194 The thiamine pyrophosphate (TPP) riboswitch employs modular

195 The thiamine pyrophosphate (TPP) riboswitch is a cis-regulat

196 g is central to the regulatory mechanisms of thiamine pyrophosphate (TPP) riboswitches and has not be

197 Thiamine pyrophosphate (TPP), a biologically active form

198 s known in bacteria responds to the coenzyme thiamine pyrophosphate (TPP), which is a derivative of v

199 The evolutionary relationships of the thiamine pyrophosphate (TPP)-dependent family of enzymes

200 Thiamine pyrophosphate (TPP)-dependent oxalate oxidoredu

201 Thiamine pyrophosphate (TPP)-sensitive mRNA domains are

202 nsiderable amount of thiamine in the form of thiamine pyrophosphate (TPP).

203 c conditions instead of its modern catalyst, thiamine pyrophosphate (TPP).

204 Thiamine pyrophosphate 1 is an essential cofactor in all

205 ic structural model of PtDXS in complex with thiamine pyrophosphate and Mg(2+) was built by homology

206 rredoxin oxidoreductase family, OOR contains thiamine pyrophosphate and three [Fe(4)S(4)] clusters.

207 Both of these metabolites compete with thiamine pyrophosphate for binding with the enzyme.

208 and to enable plants to produce thiamine and thiamine pyrophosphate for growth and development.

209 Thiamine pyrophosphate is a required coenzyme that conta

210 rexpressing lines in media containing either thiamine pyrophosphate or thiamine.

211 distinct [4Fe-4S] iron-sulfur clusters and a thiamine pyrophosphate radical upon reduction by pyruvat

212 lso found in the structure of the eukaryotic thiamine pyrophosphate riboswitch in the context of a he

213 r the aptamer domain of the Escherichia coli thiamine pyrophosphate riboswitch RNA.

214 present models of the ligand-free state of a thiamine pyrophosphate riboswitch that are derived from

215 contrast, Type II riboswitches, such as the thiamine pyrophosphate riboswitch, contain binding pocke

216 the selection outcome, and to isolate novel thiamine pyrophosphate riboswitches from a complex libra

217 ng plants were supplemented with thiamine or thiamine pyrophosphate throughout the life cycle, they g

218 ion of expression of the human mitochondrial thiamine pyrophosphate transporter (the product of the S

219 Two aptamers that recognize theophylline and thiamine pyrophosphate were embedded in tandem in the 5'

220 d in Muller cells in the presence/absence of thiamine pyrophosphate, an inhibitor of RFC.

221 thetic theophylline- and naturally occurring thiamine pyrophosphate-binding RNA aptamers as test case

222 lation of the MEP pathway and indicates that thiamine pyrophosphate-dependent enzymes may often be af

223 e in a manner very similar to the binding of thiamine pyrophosphate.

224 Because thiamine regulates intracellular glucose metabolism and

225 Using a thiamine-repressible promoter (pthiA), we showed that ge

226 when it was expressed under the control of a thiamine-repressible promoter.

227 abnormality and visual disturbances occur in thiamine-responsive megaloblastic anaemia (TRMA), an aut

228 viously defined enhancer region bound by the thiamine-responsive Thi2/Thi3/Pdc2 transcriptional activ

229 ed at the conclusion of each stage following thiamine restoration and subjects were perfused 24 hours

230 However, dietary thiamine restriction causes widespread, rapid (within 10

231 increased the risk of TB, but low vitamin A, thiamine, riboflavin, and iron status did not.

232 al phenolics, reducing sugar and B vitamins (thiamine, riboflavin, and niacin) content of steamed spr

233 vided adequate nutrient density for protein, thiamine, riboflavin, and vitamins B-6, B-12, and C but

234 Thiamine, riboflavin, niacin, vitamin B-6, folate, and v

235 Thiamine, riboflavin, pyridoxine, lutein, zeaxanthin, be

236 Most thiT genes are preceded by a thiamine riboswitch.

237 r structure and function when fed a regular (thiamine-rich) diet.

238 many Firmicutes, sometimes next to folate or thiamine salvage genes.

239 Here, thiamine status was systematically investigated in three

240 fide replaced ThiI by donating sulfur to the thiamine sulfur carrier protein ThiS.

241 R mutant phenotypes are rescued by exogenous thiamine supplementation, suggesting that blk1-R is a th

242 cells to redistribute metabolites to ensure thiamine synthesis and may define a general paradigm of

243 synthesis of AIR and thus demonstrates that thiamine synthesis can be uncoupled from the early purin

244 g enzymes and of genes involved in toxin and thiamine synthesis.

245 in nonenzymatic PRA formation sufficient for thiamine synthesis.

246 Based on a pharmacokinetic assessment of thiamine, the banana bag approach likely fails to optimi

247 Thiamine, the fursultiamine metabolite, and benfotiamine

248 We have determined that multiple thiamine (THI) genes in Saccharomyces cerevisiae are als

249 ly specific for TPP and not affected by free thiamine, thiamine monophosphate, or choline.

250 Two biosynthetic routes to the thiamine thiazole have been identified.

251 nated trees across all 10 cultivars, whereas thiamine thizole synthase and CP12, a Calvin Cycle maste

252 pproach likely fails to optimize delivery of thiamine to the central nervous system.

253 elial cells play a pivotal role in supplying thiamine to the highly metabolically active retina but n

254 gulation or biological processes involved in thiamine transport in these cells.

255 Mice lacking the gene for the high-affinity thiamine transporter (Slc19a2) have normal cochlear stru

256 face entry receptor for FeLV-A is a putative thiamine transporter (THTR1).

257 r20 was equally efficient in upregulation of thiamine transporter 1 (THTR1) by all antagonists.

258 or, KoRV-B employs a different receptor, the thiamine transporter 1 (THTR1), to infect cells.

259 y locus, uncovering a previously unsuspected thiamine transporter whose genetic variants predicted se

260 eca-spanning membrane protein related to the thiamine transporter, which functions as a pH-dependent

261 ve disorder caused by mutations in the human thiamine transporter-1 (hTHTR-1).

262 us that encodes a previously uncharacterized thiamine transporter.

263 sting that it may obtain exogenous TPP via a thiamine transporter.

264 Arabidopsis (Arabidopsis thaliana) PUT3 as a thiamine transporter.

265 ingle nucleotide polymorphisms (SNPs) in two thiamine transporters (SLC19A2/3) and their transcriptio

266 e, we hypothesized that variants in specific thiamine transporters are associated with risk of severe

267 e cat ortholog of the other of the two known thiamine transporters in mammals, THTR2, and we show tha

268 e cognate genes allowed us to establish that thiamine transporters Thi7 and Thi72 can efficiently tak

269 In this predefined subgroup, those in the thiamine treatment group had statistically significantly

270 the kinetic properties of recombinant mouse thiamine triphosphatase (mThTPase) and determined its so

271 Mammalian soluble thiamine triphosphatase (ThTPase) is a 25-kDa cytosolic

272 ith a substrate- and product-bound mammalian thiamine triphosphatase and with previously reported str

273 Homologs of Y. pestis AC-IV, including human thiamine triphosphatase, span the three kingdoms of life

274 hat specifically catalyzes the conversion of thiamine triphosphate (ThTP) to thiamine diphosphate and

275 of adenosine triphosphate, the hydrolysis of thiamine triphosphate, and the synthesis and breakdown o

276 ced experimentally via interference with the thiamine uptake and/or inhibition of the thiamin pyropho

277 essed whether FeLV-A infection might disrupt thiamine uptake into cells and, because thiamine is an e

278 Thiamine uptake is energy- and temperature-dependent, pH

279 Thiamine uptake mediated by feTHTR1 was indeed blocked b

280 epithelial ARPE-19 cells to characterize the thiamine uptake process.

281 how that FeLV-A infection can indeed disrupt thiamine uptake with pathological consequences.

282 ine THTR1 (feTHTR1) and feTHTR2 both mediate thiamine uptake, but feTHTR2 does not function as a rece

283 used a concentration-dependent inhibition in thiamine uptake, whereas the anti-trypanosomal drug, mel

284 in Escherichia coli, which catalyzed [(3)H]-thiamine uptake.

285 osphate (TPP), a biologically active form of thiamine (vitamin B(1)), is an essential cofactor in all

286 Recently, thiamine (vitamin B1) deficiency has emerged as a possib

287 Thiamine (vitamin B1) is ubiquitous and essential for ce

288 Sequence homology to a putative yeast thiamine (vitamin B1) transporter prompted us to express

289 BP) to provide high affinity recognition for thiamine (vitamin B1), an analyte of great importance to

290 n" fluorescent sensor for rapid detection of thiamine (vitamin B1).

291 nt deficiencies after gastric bypass include thiamine, vitamin B(1)(2), vitamin D, iron, and copper.

292 The lead film was formed and thiamine was accumulated at -1.25 V (vs. Ag/AgCl) on a g

293 Uptake of thiamine was adaptively regulated by extracellular subst

294 The crystalline nature of thiamine was analyzed by X-ray diffraction studies.

295 Then, the preconcentrated thiamine was reduced by scanning the potential of the el

296 ine diphosphate (TDP), and breast milk total thiamine were measured in 16 healthy Cambodian mothers a

297 zyme copurifies with a thiazole precursor to thiamine, whereas the mutant enzyme does not.

298 Total plasma thiamine, whole-blood thiamine diphosphate (TDP), and br

299 nt Cambodian mothers effectively absorb oral thiamine, with sharp increases in breast milk thiamine c

300 iption, but takes 14-16 hours to induce upon thiamine withdrawal.