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1 e in a manner very similar to the binding of thiamine pyrophosphate.
2 to the hydroxyl group of thiamine to produce thiamine pyrophosphate.
3 hiamine inhibits the enzymatic production of thiamine pyrophosphate.
4 completely protected from phosphorylation by thiamine pyrophosphate.
5 nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate.
8 a 27-fold increase in the apparent K(m) for thiamine pyrophosphate and 8-fold increase in the K(i) f
10 ic structural model of PtDXS in complex with thiamine pyrophosphate and Mg(2+) was built by homology
11 upon removal of the osmolyte, when cofactor thiamine pyrophosphate and the transacylase component of
12 rredoxin oxidoreductase family, OOR contains thiamine pyrophosphate and three [Fe(4)S(4)] clusters.
14 under the above conditions it is the lack of thiamine pyrophosphate, and not decreased CoA levels, th
15 the amino acid residues which interact with thiamine pyrophosphate are highly conserved among enzyme
16 residue Asp-260, which is located within the thiamine pyrophosphate binding motif of the alpha-ketode
17 the human E1alpha mutations in the putative thiamine pyrophosphate-binding pocket that are studied,
18 thetic theophylline- and naturally occurring thiamine pyrophosphate-binding RNA aptamers as test case
20 ration of purines and the essential cofactor thiamine pyrophosphate branch after sharing five enzymat
22 presence of the substrate, pyruvate, and the thiamine pyrophosphate cofactor, indicating close proxim
23 complex (approximately 4-5 x 10(3) kDa) is a thiamine pyrophosphate-dependent enzyme, comprising two
24 lation of the MEP pathway and indicates that thiamine pyrophosphate-dependent enzymes may often be af
28 consistent with a planar, hydroxyethylidene-thiamine pyrophosphate (HE-TPP) pi-radical, in which spi
29 does so by oxidizing the 1, 2-dihydroxyethyl thiamine pyrophosphate intermediate of transketolase and
33 ndria, could control KGDHC activity and that thiamine pyrophosphate is required for maximal enzyme ac
36 on is regulated by thiamine and suggest that thiamine pyrophosphate, or a molecule derived form it, i
37 ucose, pyridoxamine and, to a lesser extent, thiamine pyrophosphate proved to be novel and effective
38 distinct [4Fe-4S] iron-sulfur clusters and a thiamine pyrophosphate radical upon reduction by pyruvat
39 lso found in the structure of the eukaryotic thiamine pyrophosphate riboswitch in the context of a he
41 present models of the ligand-free state of a thiamine pyrophosphate riboswitch that are derived from
42 contrast, Type II riboswitches, such as the thiamine pyrophosphate riboswitch, contain binding pocke
43 the selection outcome, and to isolate novel thiamine pyrophosphate riboswitches from a complex libra
44 new thiamine amperometric biosensor based on thiamine pyrophosphate (ThDP)-dependent transketolase (T
47 ng plants were supplemented with thiamine or thiamine pyrophosphate throughout the life cycle, they g
49 the biosyntheses of histidine, purines, and thiamine pyrophosphate (TPP) contain examples of converg
50 eased KGDHC activity only in the presence of thiamine pyrophosphate (TPP) indicating that KGDHC requi
58 g is central to the regulatory mechanisms of thiamine pyrophosphate (TPP) riboswitches and has not be
59 ese compounds are normally incorporated into thiamine pyrophosphate (TPP) via steps in the purine pat
60 y labeled substrate (pyruvate) and coenzyme (thiamine pyrophosphate (TPP)), were analyzed by spectral
62 s known in bacteria responds to the coenzyme thiamine pyrophosphate (TPP), which is a derivative of v
69 ion of expression of the human mitochondrial thiamine pyrophosphate transporter (the product of the S
70 Two aptamers that recognize theophylline and thiamine pyrophosphate were embedded in tandem in the 5'
71 heterotetramer (alpha beta gamma delta), but thiamine pyrophosphate, which is required for catalytic
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