ライフサイエンスコーパス: thoracic aortic aneurysm

1 t insertion for the management of descending thoracic aortic aneurysm.

2 bruary 1996, we operated on 512 patients for thoracic aortic aneurysm.

3 condition, which is commonly associated with thoracic aortic aneurysm.

4 mortality during the resection of ascending thoracic aortic aneurysms.

5 at underwent elective surgery for descending thoracic aortic aneurysms.

6 ase PWS in finite element analysis models of thoracic aortic aneurysms.

7 WS) in finite element analysis of descending thoracic aortic aneurysms.

8 ceptors in AngII-induced atherosclerosis and thoracic aortic aneurysms.

9 repair for many patients with abdominal and thoracic aortic aneurysms.

10 emodeling and intimal expansion of ascending thoracic aortic aneurysms.

11 om loss of VSMCs occurs in primary ascending thoracic aortic aneurysms.

12 e contained 1010 patients: 670 patients with thoracic aortic aneurysm, 195 with chronic type B aortic

13 .2, and 0.4 deaths per 100 patient-years for thoracic aortic aneurysm, acute type B aortic dissection

14 .9, and 3.2 deaths per 100 patient-years for thoracic aortic aneurysm, acute type B aortic dissection

15 smooth muscle isoform of alpha-actin, cause thoracic aortic aneurysms, acute aortic dissections, and

16 Thoracic aortic aneurysm affecting the arch and proximal

17 iscusses published data on genes involved in thoracic aortic aneurysm and attempts to explain diverge

18 Thoracic aortic aneurysm and dissection (TAAD) is an aut

19 ing pathology observed in heritable forms of thoracic aortic aneurysm and dissection (TAAD).

20 however, excess TGF-beta signaling promotes thoracic aortic aneurysm and dissection in multiple diso

21 been identified to cause autosomal dominant thoracic aortic aneurysm and dissection.

22 muscle actin, have been identified to cause thoracic aortic aneurysm and dissection.

23 that individual mechanisms may contribute to thoracic aortic aneurysm and dissection.

24 pression in aortic tissue from patients with thoracic aortic aneurysm and found increased S100A12 exp

25 al controversies and uncertainties regarding thoracic aortic aneurysm and its treatment.

26 y feasible method for treatment of traumatic thoracic aortic aneurysm and may be an effective alterna

27 Thoracic aortic aneurysms and acute aortic dissections (

28 ficiency does not affect AngII-induced AAAs, thoracic aortic aneurysms and atherosclerosis.

29 lood Institute GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions)

30 al registry of GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions)

31 n of all patients with clinically recognized thoracic aortic aneurysms and constitute the majority of

32 lies identified with dominant inheritance of thoracic aortic aneurysms and dissections (TAA/dissectio

33 most common genetic alterations for familial thoracic aortic aneurysms and dissections (TAAD) are mis

34 Although thoracic aortic aneurysms and dissections (TAAD) can be

35 Thoracic aortic aneurysms and dissections (TAAD) cause s

36 Familial thoracic aortic aneurysms and dissections (TAAD) occur a

37 Thoracic aortic aneurysms and dissections (TAAD) represe

38 Heterozygous ACTA2 mutations cause familial thoracic aortic aneurysms and dissections (TAAD), but on

39 Heritable thoracic aortic aneurysms and dissections (TAAD), includ

40 A2, are the most prevalent cause of familial thoracic aortic aneurysms and dissections (TAAD).

41 e responsible for 14% of inherited ascending thoracic aortic aneurysms and dissections (TAAD).

42 Non-syndromic thoracic aortic aneurysms and dissections (TAADs) are in

43 ic isoform of alpha-actin (alpha-SMA), cause thoracic aortic aneurysms and dissections and occlusive

44 Thoracic aortic aneurysms and dissections are associated

45 es for the medical and surgical treatment of thoracic aortic aneurysms and dissections are becoming i

46 Marfan syndrome, that predispose persons to thoracic aortic aneurysms and dissections are understood

47 genetic contribution to the pathogenesis of thoracic aortic aneurysms and dissections has revealed p

48 hat these variants predispose individuals to thoracic aortic aneurysms and dissections includes the f

49 First, the pathogenesis of thoracic aortic aneurysms and dissections is better unde

50 ominant non-syndromic hearing loss, familial thoracic aortic aneurysms and dissections, and multiple

51 patients with conditions that predispose to thoracic aortic aneurysms and dissections, including MFS

52 esponsible for 25% of families with familial thoracic aortic aneurysms and dissections.

53 mutation responsible for a large family with thoracic aortic aneurysms and dissections.

54 could lead to new therapeutic strategies for thoracic aortic aneurysms and dissections.

55 This review focuses only on thoracic aortic aneurysms and dissections.

56 ooth-muscle cells (SMCs) can cause inherited thoracic aortic aneurysms and dissections.

57 S100A12 is enriched in human thoracic aortic aneurysms and dissections.

58 SNPs at the FBN1 locus associated with both thoracic aortic aneurysms and dissections.

59 the relevance of S100A12 expression to human thoracic aortic aneurysms and type A thoracic aortic ane

60 eases affecting the ascending aorta, such as thoracic aortic aneurysms and type I and II dissections,

61 ity is high in the midterm for patients with thoracic aortic aneurysm, and managing modifiable risk f

62 he variability of penetrance of both BAV and thoracic aortic aneurysm as well as the variability of t

63 ts contribute to the initiation of ascending thoracic aortic aneurysms (ATAAs) in patients with bicus

64 n syndrome (MFS) is known to cause ascending thoracic aortic aneurysms (ATAAs).

65 Repair of thoracoabdominal and thoracic aortic aneurysm by the traditional clamp-and-go

66 t-to-treat complications in the treatment of thoracic aortic aneurysms by endovascular stent-grafting

67 nd in approximately 25% of clinically stable thoracic aortic aneurysm cases.

68 e is remarkably similar to a subset of human thoracic aortic aneurysms caused by mutations in SMC con

69 ents undergoing elective surgical repair for thoracic aortic aneurysm, despite similar preoperative r

70 0A12 protein expressed in all cases of acute thoracic aortic aneurysm dissection and in approximately

71 o human thoracic aortic aneurysms and type A thoracic aortic aneurysm dissection and to study mechani

72 ts who underwent repair of chronic ascending thoracic aortic aneurysms from 1986 to present.

73 se models and the discovery of several novel thoracic aortic aneurysm genes, the involvement of the t

74 A genetic predisposition to thoracic aortic aneurysm has been established, and gene

75 Overall survival for thoracic aortic aneurysms has improved significantly in

76 rly experiences with endovascular grafts for thoracic aortic aneurysms have met with good to moderate

77 Managing thoracic aortic aneurysms identified incidentally by inc

78 patients that underwent TEVAR for descending thoracic aortic aneurysm in the MOTHER database and 231

79 ort the hypothesis that FBN1 mutations cause thoracic aortic aneurysms in patients who do not have th

80 trophy is thought to be a cause of ascending thoracic aortic aneurysms in the elderly.

81 Thoracic aortic aneurysm is a potentially life-threateni

82 Although a virulent disease, thoracic aortic aneurysm is an indolent process.

83 The risk of developing thoracic aortic aneurysm is increased more than 17-fold

84 modern understanding of the pathogenesis of thoracic aortic aneurysm is quite limited.

85 including both abdominal aortic aneurysm and thoracic aortic aneurysm, is the cause of death of 1% to

86 of the SMC contractile unit, cause familial thoracic aortic aneurysms leading to acute aortic dissec

87 redisposition for progressive enlargement of thoracic aortic aneurysms leading to type A dissection (

88 ellular remodeling of the media in ascending thoracic aortic aneurysms may be an initial adaptive res

89 an unspecified site, which may include some thoracic aortic aneurysms, may have underestimated the t

90 mputed tomographic angiography of descending thoracic aortic aneurysms (n=10 total, 5 fusiform and 5

91 Up to 20% of individuals who have thoracic aortic aneurysms or acute aortic dissections bu

92 had any significant effect on AngII-induced thoracic aortic aneurysms or atherosclerosis.

93 ted the hypothesis that FBN1 mutations cause thoracic aortic aneurysms or dissections in patients who

94 cation of individuals at risk for developing thoracic aortic aneurysms or dissections.

95 Ruptured descending thoracic aortic aneurysm (rDTAA) is a life-threatening d

96 ach for the treatment of ruptured descending thoracic aortic aneurysms (rDTAA).

97 DHCA has been implemented in ascending thoracic aortic aneurysm resection whenever the anatomy

98 This study examined trends in mortality from thoracic aortic aneurysm (TAA) and aortic dissection (AD

99 n aortic collagen and elastin content during thoracic aortic aneurysm (TAA) development in a murine m

100 Mutations in fibrillin-1 are associated with thoracic aortic aneurysm (TAA) in Marfan syndrome.

101 Thoracic aortic aneurysm (TAA) is a common progressive d

102 issection (AoD) is a serious complication of thoracic aortic aneurysm (TAA).

103 Genetic aortopathy (GA) underlies thoracic aortic aneurysms (TAA) in younger adults.

104 N) with 7247 (65%) nonruptured, degenerative thoracic aortic aneurysms (TAA), 2701 (24%) descending a

105 ng-term survival of patients with descending thoracic aortic aneurysms (TAAs) after open and endovasc

106 Thoracic aortic aneurysms (TAAs) and valvular insufficie

107 Thoracic aortic aneurysms (TAAs) are common, but experim

108 Thoracic aortic aneurysms (TAAs) develop secondary to ab

109 The cause of thoracic aortic aneurysms (TAAs) is poorly understood.

110 Marfan syndrome and other forms of inherited thoracic aortic aneurysm taking CCBs display increased r

111 ACTA2, are the most common cause of familial thoracic aortic aneurysms that lead to dissection (TAAD)

112 From 1992 to 1996, 85 patients with thoracic aortic aneurysm underwent stent-graft placement

113 amily with autosomal-dominant inheritance of thoracic aortic aneurysms variably associated with the b

114 areas per examination was 1.6 (18 of 11) in thoracic aortic aneurysms versus 0.25 (14 of 57) in abdo

115 genes known to be associated with BAV and/or thoracic aortic aneurysm was performed.

116 l ascending thoracic aortas and 29 ascending thoracic aortic aneurysms was performed by directly meas

117 which men are affected predominately, 51% of thoracic aortic aneurysms were identified in women who w

118 Thoracic aortic aneurysms were significantly more likely

119 by use of genomic DNA from two patients with thoracic aortic aneurysms who did not have the Marfan sy