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1 ction of NFkappaB (five-fold) and cyclin D1 (three-fold).
2 of thromboembolic complications some two to three fold.
3 e median survival of TET1-high AML mice over three fold.
4 up to six-fold, and its cell volume by about three-fold.
5 n findings, based on resting-state fMRI, are three-fold.
6 the hit frequency from the chemical library three-fold.
7 l plasma membrane to cytoplasmic H(+)-ATPase three-fold.
8 lated a TGF-beta reporter construct promoter three-fold.
9 the overall incidence of respiratory failure three-fold.
10 ne and NGF both increased levels of MKP-2 by three-fold.
11 The aims of this study were three-fold.
12 Case rates differed four-fold and mortality three-fold.
13 ), thus increasing the detection sensitivity three-fold.
14 iltered and reabsorbed glucose up to two- to three-fold.
15 ed in EC hyperproliferation, increased IL-32 three-fold.
16 ing examination increased the risk of an IBC three-fold.
17 on prolonged cardiac allograft survival over three folds.
19 he objective of this retrospective study was three fold: 1) to determine whether a gene signature ass
20 e contributions of the proposed approach are three-fold: 1) We consider all possible genotype models
21 onary intervention trials has ranged by over three-fold (16% to 56%) and is greater among the acute c
22 d pH 4 apoMb intermediate is composed of the three folded A, G, and H helices and contains 38% helica
24 e frequency of malformations is about two to three-fold above the background rate and is dose-related
25 bloodstream infection increased by more than three-fold after the second dressing disruption and by m
28 citation increased the dextran concentration three-fold and decreased blood flow 50% of the baseline
29 reased fluorescence intensities from two- to three-fold and similar decreases in lifetimes were obser
30 talyzed CO evolution systematically rises by three-fold and the specific activity for catalyzed H2 ev
31 at increased the incidence of ARDS by nearly three-fold and was associated with more severe nonpulmon
32 fold, monocyte vitamin D receptor expression three-fold, and 24-hydroxylase expression; therapy decre
33 n plant transcription factor interactions by three-fold, and reveals previously unknown family-specif
35 lso show that charged residues at the fibril three-fold apices provide the majority of the binding fr
36 conditions that enhance neurite outgrowth by three-fold as compared to unstimulated or wild-type (WT)
38 topes on or near protrusions surrounding the three-fold axes, raising the possibility that AAV-2 migh
39 o those of mammalian TRICs and implicate the three-fold axis in the allosteric regulation of the chan
40 identified a CTD-CTD interface at the local three-fold axis in the cryoEM map and confirmed its func
41 The location of the epitope close to the three-fold axis is consistent with the previous analysis
42 also identified subunit interactions at each three-fold axis of the capsid that are maintained throug
43 three separate protrusions surrounding each three-fold axis, and a channel at each five-fold axis.
46 on the alkynyl bonds enabled a copper-free, three-fold azide-alkyne cycloaddi-tion at 50 degrees C.
48 of bleaching-level thermal stress increased three-fold between 1985-91 and 2006-12 - a trend climate
49 s of Hhex(-/-) mice were elevated as much as three-fold between E9.5 and E11.5, and treatment of cult
52 analysis reduced these variations as much as three-fold, but only within a narrow range of focus and
56 rating action of HCO3(-) is slowed more than three-fold by the carbonic anhydrase inhibitor acetazola
57 arget for chemoprevention, was induced about three-fold by the RARalpha-selective agonist Am580, in T
59 double-jump experiments demonstrate that all three folding channels lead directly to native dimer; an
60 roduces actuation strains of up to 45% and a three-fold chemical amplification of the controlling lig
69 n a randomized study to be associated with a three-fold decrease in arterial rupture in vascular EDS
71 intestinal deletion of the HuR gene caused a three-fold decrease in tumor burden characterized by red
72 finity of semaglutide (0.38 +/- 0.06 nM) was three-fold decreased compared to liraglutide, whereas th
73 attesting that the canting spin stripes are three-fold degenerate states akin to helices and the mul
76 accuracies in current BPLM theory, including three-fold discrepancies in torsional persistence length
79 ge of 25 to 1,000 mg, and there is a 1.5- to three-fold drug accumulation at steady-state after once-
80 pecifically, our 60 vol.% Ap-SFRP displays a three-fold elevation in tensile and flexural strength, a
85 which spectrin is able to undergo a seamless three-fold extension while remaining a linear filament,
89 nd disease and a striking increase in warts: three-fold for patients on antiretroviral therapy and si
92 as a serum creatinine increase greater than three-fold from baseline, or greater than or equal to 4.
93 rum creatinine increase greater than two- to three-fold from baseline; stage 3 as a serum creatinine
94 opolymer could extend ibuprofen release over three-fold (from 3days to >9days) whilst the release of
95 m 15 mg to 60 mg, resulting in a two-fold to three fold gradient of mean trough drug exposure (16.0-4
96 =1.5 hrs from the health centre had a two to three fold greater risk of death than children who lived
97 of infections during the exposure period was three-fold greater (adjusted hazard ratio [AHR], 2.93; 9
99 The unadjusted mortality rate was nearly three-fold greater in the acute lung injury group (23.9%
102 rom a low-elevation provenance had more than three-fold greater recruitment to their third year than
103 e the mean in number predicted a two-fold to three-fold greater risk for an adult major depressive ep
104 variable modeling, depressed patients have a three-fold greater risk of dying than nondepressed patie
105 in efficiency of lift production is at least three-fold greater than reported for other insects.
107 2,350 +/- 826 ng x h/mL, respectively) were three-fold greater than those for oral 5-FU (38.1 +/- 7.
108 rtial thromboplastin times that were two- to three-fold greater than those observed in saline-infused
109 d larvae maintained chemical defenses nearly three-fold greater than those of siblings reared in stre
110 or by bath hypotonicity, were approximately three-fold greater when positioned next to intercalated
111 and anabolic activity (apposition rate) were three-fold greater, calcified spongiosa decreased by two
112 d higher concentrations of bound phenols and three-fold higher concentrations of lignin phenols than
114 n liberation and in vitro accessibility were three-fold higher from spinach puree compared to whole l
118 yr), the prevalence of CKD was approximately three-fold higher in those with a history of hip fractur
119 R haplotype is responsible for an average of three-fold higher insulin expression than class I VNTR i
120 t 60% of the tested primary NSCLC tumors had three-fold higher JNK2 protein and two- to three-fold hi
121 d three-fold higher JNK2 protein and two- to three-fold higher JNK2alpha mRNA expression than normal
122 six-fold higher neutrophil infiltration and three-fold higher level of myeloperoxidase activity than
123 ributable to tobacco smoking rather than the three-fold higher prevalence of oral HPV infection in th
124 ses show that the G allele confers a two- to three-fold higher promoter activity and stronger binding
125 irinotecan plus bolus 5-FU/leucovorin had a three-fold higher rate of treatment-induced or treatment
126 als with two APOL1 risk alleles had a nearly three-fold higher risk for ESRD compared with those with
128 nd a limit of detection of 1pg/ml, which was three-fold higher than aptamer alone sensor for PSA.
131 rexpressing plants was found to be more than three-fold higher than that of wild-type, but again the
132 HGF levels in obese subjects were more than three-fold higher than those of lean subjects (2,462 +/-
134 ne, and Mg/adenosine and lidocaine group had three-fold higher urinary output (2.1 mL//kg/hr [95% CI,
135 se per 1-SD higher log(e) CRP concentration (three-fold higher) were 1.63 (95% CI 1.51-1.76) when ini
137 two-fold (HR, 1.94; 95% CI, 1.72, 2.18) and three-fold (HR, 3.05; 95% CI, 2.38, 3.90) higher risk of
139 one; (2) more genes are upregulated at least three-fold in response to Eyeless+signaling factors comp
142 umber of IL-4-producing CD4+ cells increased three-fold in the trauma patients compared with healthy
144 ontrols without bipolar disorder indicates a three-fold increase (risk ratio [RR] 3.22 [95% CI 2.41-4
145 finding rate was 1.9 patients/month nearly a three-fold increase compared with our historical control
146 ited a long circulation half-life of ~45h, a three-fold increase from the unmodified native version,
147 ssed proinflammatory markers, supported by a three-fold increase in active alpha(V)beta(3) integrin.
148 gt expression increased twofold, including a three-fold increase in aldosterone synthase expression i
150 rom n- to p-type, accompanied by a more than three-fold increase in carrier mobility, up to muh appro
151 rea, the Janus catalyst exhibits a more than three-fold increase in catalytic efficiency compared to
152 trols, in cirrhotic human livers there was a three-fold increase in CB1 receptors on isolated vascula
154 erved during micellization, for which only a three-fold increase in ClO4(-) concentration was necessa
155 e-CPP, Tat-induced GT-tg mice demonstrated a three-fold increase in cocaine-CPP over the response of
157 rrying versus tumor-free mice, we observed a three-fold increase in differentially expressed miRNAs.
159 amate receptor agonist that causes a two- to three-fold increase in hypocotyl elongation on Arabidops
160 mechanical ventilation was associated with a three-fold increase in in-hospital mortality (36% vs. 10
162 d, as in the circulation, but demonstrated a three-fold increase in KIR expression compared with NKG2
163 cimens, 4 + 3 cancers were associated with a three-fold increase in lethal PCa compared with 3 + 4 ca
164 micromol/kg intraperitoneally) resulted in a three-fold increase in leukocyte adhesion, compared with
167 the presence of target muscle cells causes a three-fold increase in NO production by macrophages, wit
168 a few hours after UV, we show an approximate three-fold increase in recombinants in the TLS mutants o
169 t the highest decile of risk had a more than three-fold increase in risk of melanoma compared with th
171 of the viability of the high MMP cells and a three-fold increase in the capsase-3 enzymatic activity.
172 he hemisphere ipsilateral to the hematoma, a three-fold increase in the concentration of glycine was
173 nd provides significant stabilization with a three-fold increase in the intermolecular nonbonded inte
174 les of estradiol demonstrated greater than a three-fold increase in the mortality rate for the highes
175 of non-smokers is associated with a two- to three-fold increase in the odds of developing periodonti
177 e waiting list was associated with an almost three-fold increase in the RR for death for patients wit
178 from the ER with a concomitant approximately three-fold increase in their level on the cell surface.
179 s in tumor burden in Smad3(+/-) mice, with a three-fold increase in TLR7 expression compared to contr
180 highest F1-V protein accumulation, almost a three-fold increase of F1-V protein levels in fruit than
181 P groups, but P. gingivalis LPS1690 showed a three-fold increase on IL-10 production in the NP group
182 result the particle transport experienced a three-fold increase when compared with the traditional s
183 ome peripheral blood mononuclear cells had a three-fold increased ability to differentiate into fibro
184 on of both CKD and MAC was associated with a three-fold increased risk for death compared with those
186 2% allele frequency in controls that confers three-fold increased risk of ALL in children of European
188 admission was independently predictive of a three-fold increased risk of delirium (odds ratio 3.1 [1
192 s of liver tumor formation revealed striking three-fold increases in tumor burden in Smad3(+/-) mice,
193 ion we found significant (p < .0006) two- to three-fold increases in venous and arterial F2-isoprosta
194 tion of apoptotic hepatocellular death and a three-fold increment in the number of proliferating hepa
195 in a time and dose-dependent manner, with a three-fold induction reached 8 h following gamma-irradia
196 ucture of the tubular assembly shows, at the three-fold interface, a three-helix bundle with critical
197 with >/= 2 clinical conditions, there was a three-fold, inverse association between age and mean OHI
198 of ciprofloxacin resistance increased two to three-fold, irrespective of recent sexual contact overse
203 le APOA5*3-defining allele (19W) resulted in three fold lower ApoAV plasma levels, consistent with ex
204 shows that it binds single-stranded DNA with three-fold lower affinity than ssRNA of the same length
205 vitellogenin mRNA 3'-UTR probe with a two to three-fold lower affinity than to a Drosophila dodecasat
206 te and bound to the c-myc CRD with a two- to three-fold lower affinity than to the vitellogenin mRNA
207 rate of GC apoptosis was found to be two- to three-fold lower among aggregated cells, as compared wit
210 ugh F2-isoprostane levels were approximately three-fold lower in patients randomized to hypothermia v
213 structures generated from trisulfonates with three-fold molecular symmetry are the topological equiva
214 ritic profiles containing GABA-labeling were three fold more abundant than GABA-labeled axon terminal
216 The encapsulated hUCMSCs synthesized nearly three-fold more bone minerals than the hBMSCs in vitro.
217 centile, the APOA5*3 haplotype was more than three-fold more common in the group with high plasma tri
218 ng drug elution--near zero-order release was three-fold more efficient at depositing drug in the sten
219 pitalized longer (i.e., >7 days) are two- to three-fold more likely to be infected with a pathogen po
221 tment or nontreatment, the post-PET plan was three-fold more likely to lead to treatment than nontrea
222 Cs formed 70% larger bone nodules containing three-fold more mineralized bone compared with long-bone
223 wever, in the long-term animals, two-fold to three-fold more new bone width (</= 0.004) was seen arou
225 uding differential up- and down-regulation (>three folds) of eight flowering time-associated genes (i
226 biomass in the nutrient-rich crust increased three-fold one week after watering, whereas it did not c
229 estricted rats, Cp mRNA expression increased three-fold (P < 0.01) and protein expression increased 1
230 exposure increased the k3-tidal strain slope three-fold (p = 0.009), without significant lung edema.
231 in-treated net significantly reduced (nearly three-fold, p<0.0001) culicine landings inside enclosure
233 g properties of catalytic Pd on-top sites vs three-fold Pd hollow sites and is therefore of major rel
236 a conformational epitope at the vertex of a three-fold protrusion on the viral surface, thereby simu
240 of the eccentric contractions varied over a three-fold range and overlapped with that of the isometr
241 gh flow indicates that increasing blood flow three-fold recruited injured vessels and/or increased va
242 omen shows a similar tendency with an almost three fold reduction in the probability to have a Down s
243 These experiments reveal an approximately three-fold reduction in activation energy for ion transp
244 ,25(OH)(2)D(3) levels were associated with a three-fold reduction in FGF23 levels that were increased
245 rapy results in central tumor necrosis and a three-fold reduction in human tumor vascular density.
247 myloid precursor protein (hAPP) results in a three-fold reduction in the number of parenchymal amyloi
248 levels of catalase in the brain resulting in three-fold reductions in inflammation and complete neuro
254 k of developing bipolar disorder (BD), and a three-fold risk of developing major depressive disorder
255 NMR spectroscopy, we determined a symmetric three-fold rotational potential with a barrier of 10.2 k
256 ctroscopy, show that the molecule exhibits a three-fold rotational symmetry and adopts a folded confo
258 he octahedral symmetry of the ligand and the three-fold rotational symmetry of the TolC entrance dete
259 e-containing fungus Neocallimastix that have three-fold sequence repeats and signature motifs that, a
260 educed intimal and medial cell proliferation three-fold seven days after stenting and virtually elimi
261 A analogues were chemically synthesized; all three folded significantly faster in the glutathione-bas
265 ife of approximately 40 hours, approximately three-fold steady-state accumulation, dose-proportional
266 nd torsional behaviors; Z-DNA to be at least three-fold stiffer than random-sequence dsDNA, with a ne
271 e-directed, catalyst-assisted synthesis of a three-fold symmetric, extended pyridinium-based, cage-li
273 parin (LMWH) binds to Abeta40 fibrils with a three-fold-symmetric (3Q) morphology with higher affinit
276 the icosahedral virus surface, 60 with quasi-three-fold symmetry and 20 coincident with the icosahedr
278 ment, with carbonyl O atom positioned on the three-fold symmetry axis of the NH3(+) group (angle C(ep
281 imately 5-7 A M35-M35 distance in the fibril three-fold symmetry structure is likely to relate to M35
283 molecular machine through twelve-, six- and three-fold symmetry, and provides insights into molecula
287 ophic chondrocyte zone in the cKO-mice was > three-fold thicker than that in the age-matched control,
288 vaccine approach, HAd-H5HA vaccine induced a three-fold to eight-fold increase in HA-518-epitope-spec
293 oindolinone to the target structures are the three-fold use of ruthenium catalysts, first in azepine
295 the CDDP IC(50) and increased cell survival three-fold, while attenuating AXL in overexpressing cell
296 increased the steady-state current by about three-fold, while the peak current was reduced by 30% on
297 ond post-transplantation rituximab increased three-fold with each V allele (robust z = 2.08, P = .038
300 nces to the tumors of HCC-bearing mice about three-fold without a parallel increase in normal tissues
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