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1 epends on the RTKs activating the AKT serine/threonine kinase.
2 activating phosphorylation by Mst1, a serine/threonine kinase.
3  phytochromes are autophosphorylating serine/threonine kinases.
4 amino acid sequences of human protein-serine/threonine kinases.
5  segment conformation of tyrosine and serine/threonine kinases.
6  the protein kinase D (PKD) family of serine/threonine kinases.
7 rylation at Ser133 by various protein serine/threonine kinases.
8 APK)-related kinase, MAPK interacting serine/threonine kinase 1 (MKNK1), in viral entry.
9 ric inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK-1).
10 uired caspase-8, receptor-interacting serine/threonine kinase 1 (RIPK1), and Fas-associated death dom
11 -activated protein kinase interacting serine/threonine kinase 1 activation significantly suppresses T
12 educed levels of receptor-interacting serine-threonine kinase 1 and CRC cell necroptosis.
13  lower levels of receptor-interacting serine-threonine kinase 1 and shorter survival times of patient
14 ivated protein kinase and phospho-AKT serine/threonine kinase 1 signaling pathways, as well as increa
15  Ripk1 (receptor (TNFRSF)-interacting serine-threonine kinase 1) expression, and miR-155-5p inhibitio
16 in kinase) and MNK1 (MAPK-interacting serine/threonine kinase 1) signaling.
17 TBK1 (TANK-Binding Kinase 1)-AKT (AKT serine/threonine kinase 1)-IRF3 (interferon regulatory factor 3
18 ed levels of the receptor-interacting serine-threonine kinase 1, a mediator of necroptosis, in CRC ce
19 fibroblasts from receptor interacting serine/threonine kinase 1-knockout mice or their WT littermates
20 te-oriented kinase (LOK), also called serine threonine kinase 10 (STK10), is synthesized mainly in ly
21                  The tumor suppressor serine/threonine kinase 11 (LKB1/STK11) is one of the most freq
22                  The tumor suppressor serine/threonine kinase 11 (STK11 or LKB1) is mutated in 20-30%
23                                       Serine/threonine kinase 11 (STK11, also known as LKB1) function
24  (LKB1) tumor suppressor gene, Stk11 (serine threonine kinase 11), in the fetal Mullerian duct mesenc
25  Liver kinase B1 (LKB1, also known as serine/threonine kinase 11, STK11) is a tumor suppressor mutate
26 served interactions included those of serine/threonine kinase 16 (STK16), hippocalcin-like 1 (HPCAL1)
27 containing (Nod)/receptor-interacting serine-threonine kinase 2 (Ripk2) signals in DCs.
28 mediated through receptor-interacting serine/threonine kinase 2, and the transcriptional regulator CC
29 and in vivo by microtubule-associated serine/threonine kinase 3 (MAST3 kinase), an enzyme of previous
30 cally depends on receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase doma
31 ice deficient in receptor-interacting serine-threonine kinase 3 (RIPK3).
32                We also validated that serine/threonine kinase 35 is a target of miR-377 using a dual
33 lin-1) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal differentiation.
34      Among these genes, we identified serine/threonine kinase 40 (STK40), a negative regulator of NF-
35      We identified GCK-1, a conserved serine/threonine kinase [8], as a putative novel anillin intera
36 KD2) is a member of the PKD family of serine/threonine kinases, a subfamily of the CAMK super-family.
37 ng protein kinase (HIPK) 2, a nuclear serine/threonine kinase, activates CREB through Ser271 phosphor
38 cificity kinase and both tyrosine and serine/threonine kinase activities are required for its functio
39         It is an adaptor protein with serine/threonine kinase activity and has been shown to positive
40                                  Pak2 serine/threonine kinase activity is required for stromal-derive
41 terms protein kinase activity/protein serine threonine kinase activity, response to heat and reactive
42         The p.E80K mutation abolished serine/threonine kinase activity, resulting in altered ICK subc
43 the mutation blocks both tyrosine and serine/threonine kinase activity, whereas Y243 and Y250 are mor
44 , including the regulation of protein serine/threonine kinase activity.
45 ing protein essential for positioning serine-threonine kinases adjacent to target phosphorylation sit
46 mice lacking specific isoforms of the serine/threonine kinase AKT and bone marrow chimeras, we found
47 hosphatidylinositol-3-OH kinase), the serine-threonine kinase Akt and the metabolic checkpoint kinase
48                 AKT3, a member of the serine/threonine kinase AKT family, is involved in a variety of
49          Here we demonstrate that the serine/threonine kinase Akt has a critical role in regulating n
50       Pharmacologic inhibition of the serine/threonine kinase Akt has recently been shown to promote
51          Although the role of the key serine/threonine kinase Akt in promoting CNS myelination has be
52      Here we examined the role of the serine/threonine kinase Akt in the generation of protective imm
53                                   The serine/threonine kinase AKT is a key mediator of cancer cell su
54                                   The serine-threonine kinase Akt is a key regulator of cell prolifer
55                     Activation of the serine-threonine kinase Akt promotes the survival and prolifera
56                                   The serine-threonine kinase AKT regulates proliferation and surviva
57 ckpoint kinase complex mTORC2 and the serine-threonine kinase Akt, and loss of this activity restores
58 depends on the activation of PI3K and serine-threonine kinase Akt, and protein synthesis relies on th
59                                   The serine/threonine kinase Akt, which regulates HTT function, resc
60 phate (PIP3), and the activity of the serine/threonine kinase AKT.
61 activation-induced phosphorylation of serine-threonine kinases Akt and mechanistic target of rapamyci
62              Akt is a family of three serine-threonine kinases, Akt1, Akt2, and Akt3.
63  kinases are tyrosine kinases, though serine/threonine kinases also play key roles in some malignanci
64                             LKB1 is a serine/threonine kinase and a commonly mutated gene in lung ade
65 ion of general control nonrepressed 2 serine/threonine kinase and increased expression of mammalian t
66 ion of general control nonrepressed 2 serine/threonine kinase and mammalian target of rapamycin (both
67 focus on coordination of postsynaptic serine/threonine kinase and phosphatase signaling by scaffold p
68       The liver kinase B1 (LKB1) is a serine/threonine kinase and tumor suppressor that couples bioen
69 ATIONALE: LKB1 (liver kinase B1) is a serine/threonine kinase and tumor suppressor, which regulates t
70               Here we explore how key serine-threonine kinases and their substrates mediate T cell si
71  expression of the oncogenic PIM1/2/3 serine/threonine kinases, and as PIMs modulate transcriptional
72 ex comprises APC, Axin, beta-catenin, serine/threonine kinases, and other proteins.
73   We show that the apically localized serine/threonine kinase aPKC directly phosphorylates an N-termi
74  the protein kinase D (PKD) family of serine/threonine kinases are major targets for tumor-promoting
75 rum glucocorticoid kinase 1 (SGK1), a serine/threonine kinase, as an essential node downstream of IL-
76 ify CDK5, a predominantly cytoplasmic serine/threonine kinase, as an important regulator of DLC1 func
77 ous to penicillin-binding protein and serine/threonine kinase associated (PASTA) domains, and binds f
78 llular penicillin-binding-protein and serine/threonine kinase-associated (PASTA) domains which bind m
79 terial Penicillin-binding-protein And Serine/Threonine kinase-Associated (PASTA) kinases is of partic
80 ent cations and contains a functional serine/threonine kinase at its carboxyl terminus.
81 1 is phosphorylated by the DNA damage serine/threonine kinase ATM, resulting in increased levels of F
82 led to reduced phosphorylation of the serine/threonine kinases ATM and Chk2 and of histone H2AX after
83 rations in FA-complex genes or in ATM serine/threonine kinase (ATM) exhibited significantly longer tr
84 ment of ataxia-telangiectasia mutated serine/threonine kinase (ATM) to the damaged site, where it pla
85 ion of Gene 33 triggers DDR in an ATM serine/threonine kinase (ATM)-dependent fashion and through pat
86 l components is phosphorylated by the serine-threonine kinase, ATM.
87 terized the activation process of the serine/threonine kinase Aurora-A by phosphorylation and by its
88              Classically defined as a serine/threonine kinase, BIK1 is shown here to possess tyrosine
89                      Mutations in the serine/threonine kinase BRAF are found in more than 60% of mela
90 ement within the RAS/ERK pathway, the serine/threonine kinase BRAF plays a key role in development an
91 h a constitutively active form of the serine/threonine kinase BRAF was expressed in neurons gated by
92              The B-Raf proto-oncogene serine/threonine kinase (BRAF) gene is the most frequently muta
93  protein kinase B-Raf proto-oncogene, serine/threonine kinase (BRAF) is an oncogenic driver and thera
94 ability, and the B-Raf protooncogene, serine/threonine kinase (BRAF), mutation) in the Nurses' Health
95  as PLK1 (Polo-like kinase 1), C-MYC, serine-threonine kinase BUB1B and regulates their expression.
96 nd protein phosphatase-1, as well the serine/threonine kinases CaMKII and PKA.
97     Here we report that the conserved serine/threonine kinase, casein kinase II (CK2), promotes miRIS
98 aining both an ion channel pore and a serine/threonine kinase (chanzyme).
99 he LNAA leucine for activation of the serine-threonine kinase complex mTORC1 and for expression of th
100 tion of their primary sequences, many serine-threonine kinases display a significant preference for s
101                                 A key serine/threonine kinase distantly related to the MAPK family is
102 ate 1970s, is composed of at least 10 serine/threonine kinases, divided into three groups based on th
103 apoptotic gene FASTKD2 (fas-activated serine/threonine kinase domains 2; rs7594645-G) with better mem
104 ral and signaling motifs, including 2 serine/threonine kinase domains, SK1 and SK2, present at the CO
105  show that the kinase activity of the serine/threonine kinase encoded by TAOK2 is required for spine
106   The Escherichia coli eukaryote-like serine/threonine kinase, encoded by yeaG, is expressed in respo
107 , we find that phosphorylation of the serine/threonine kinase ERK (pERK) preferentially occurs in end
108 nally reported as an inhibitor of the serine/threonine kinase ERK, a kinase that is distinct in the s
109 well appreciated that eukaryotic-like serine/threonine kinases (eSTKs) control essential processes in
110 ber of the protein kinase C family of serine/threonine-kinases, expression varies during human megaka
111 sactivation of microtubule associated serine/threonine kinase family member 4 (MAST4).
112 cting NEK2, a member of the NIMA-like serine-threonine kinase family, in a patient with congenital he
113                     The Fas-activated serine/threonine kinase (FASTK) family of proteins has recently
114                      TOR, an atypical serine/threonine kinase, forms two distinct complexes TORC1 and
115 tein kinase C constitutes a family of serine-threonine kinases found in all eukaryotes and implicated
116 arget of rapamycin complex 1 (mTORC1) serine/threonine kinase from the lysosomal membrane.
117 ein kinase (AMPK), a highly conserved serine/threonine kinase, functions as a critical metabolic sens
118 get of rapamycin (mTOR), an essential serine/threonine kinase, functions in biochemically distinct mu
119           Somatic inactivation of the serine/threonine kinase gene STK11/LKB1/PAR-4 occurs in a varie
120  in vitro functional studies, a novel serine/threonine kinase gene, unc-51-like kinase 4 (ULK4), as a
121         We previously showed that the serine/threonine kinase, glycogen synthase kinase, GSK-3alpha/b
122     Biallelic inactivation of LKB1, a serine/threonine kinase, has been detected in 30% of lung adeno
123                                   The serine/threonine kinase HIPK2 functions as a regulator of devel
124 53Ser46(P) by binding and stabilizing serine-threonine kinase HIPK2.
125  One of these binding partners is the serine/threonine kinase Hrr25p.
126                                       Serine/threonine kinase IKBKE is a newly identified oncogene; h
127                                   The serine/threonine kinase IL-1R-associated kinase (IRAK)4 is a cr
128 ibrain (Mnb; also known as Dyrk1A), a serine/threonine kinase implicated in autism spectrum disorder
129 (GSK-3, isoforms alpha and beta) is a serine-threonine kinase implicated in cellular processes.
130  kinase kinase kinase 4 (MAP4K4) is a serine/threonine kinase implicated in the regulation of many bi
131 Protein kinase C (PKC) is a family of serine/threonine kinases implicated in a variety of physiologic
132 e c-Jun N-terminal kinases (JNKs) are serine/threonine kinases implicated in the pathogenesis of vari
133 PKD) is a family of stress-responsive serine/threonine kinases implicated in the regulation of divers
134 the highly overexpressed genes of the serine/threonine kinase in CTCL.
135 point kinase 2 (CHK2) is an important serine/threonine kinase in the cellular response to DNA damage.
136                 ULK1/Atg1 is the only serine/threonine kinase in the core autophagy pathway and thus
137 ich encodes a type I activin receptor serine/threonine kinase, in 21% of DIPG samples.
138 , we identified PIM1, a non-essential serine-threonine kinase, in a synthetic lethal interaction with
139  a target of casein kinase 2 (CK2), a serine/threonine kinase, in proliferating myoblasts.
140 ycin (TOR), an evolutionary conserved serine/threonine kinase, in the plant defense response.
141                Enzastaurin is an oral serine/threonine kinase inhibitor antitumor agent.
142                             mTOR is a serine/threonine kinase involved in a variety of cellular activ
143 rylation-regulated kinase DYRK1A is a serine/threonine kinase involved in neuronal differentiation an
144 e-3 (GSK3) are ubiquitously expressed serine-threonine kinases involved in a plethora of functions ra
145 an evolutionarily conserved family of serine/threonine kinases involved in mitosis and meiosis.
146 ously determined that a transmembrane serine/threonine kinase (IreK) and its cognate phosphatase (Ire
147                  The Aurora family of serine/threonine kinases is essential for mitosis.
148  (CK1alpha), a ubiquitously expressed serine/threonine kinase, is a key negative regulator of oncogen
149                               mTOR, a serine/threonine kinase, is a master regulator of cellular meta
150             Liver kinase B1 (LKB1), a serine/threonine kinase, is a tumor suppressor and metabolic re
151 at casein kinase 1 alpha (Csnk1a1), a serine-threonine kinase, is essential for AML cell survival in
152       Protein kinase C (PKC) theta, a serine/threonine kinase, is involved in TH2 cell activation and
153                                Akt, a serine/threonine kinase, is known to increase cell survival by
154 ber of the polo-like kinase family of serine-threonine kinases, is a master regulator of centriole du
155 PK1, a member of mammalian Ste20-like serine/threonine kinases, is lost in >95% pancreatic cancer thr
156  the phosphorylation by WNKs of other serine-threonine kinases known as SPAK-OSR1.
157 optosis signal-regulating kinase 1, a serine/threonine kinase, leads to improvement in inflammation a
158 kinase (called microtubule-associated serine/threonine kinase like [Mastl] in mammals) is essential f
159 revious study, we identified TRIB1, a serine-threonine kinase-like molecule, as a biomarker of chroni
160                     We found that the serine/threonine kinase LKB1 and one of its substrates, AMPK, r
161                                   The serine/threonine kinase LKB1 has been identified as a potent su
162                                   The serine/threonine kinase LKB1 is a tumor suppressor whose loss i
163               We demonstrate that the serine/threonine kinase LKB1 regulates MCU expression, mitochon
164 ivity of the evolutionarily conserved serine/threonine kinase mammalian target of rapamycin (mTOR).
165                                   The serine/threonine kinase mammalian/mechanistic target of rapamyc
166 -activated protein kinase-interacting serine-threonine kinases MAP kinase-interacting kinase 1 (Mnk1/
167                  In recent years, the serine/threonine kinase mechanistic target of rapamycin (mTOR)
168  show that the MAP kinase interacting serine/threonine kinase (MNK)-eukaryotic translation initiation
169  the mechanistic target of rapamycin (serine/threonine kinase; MTOR) pathway in the regulation of neu
170 ntify protein kinase C (PKC) gamma, a serine/threonine kinase mutated in the neurodegenerative diseas
171       In this study, we show that the serine/threonine kinase Ndr2 controls integrin-dependent dendri
172                     PRL activates the serine/threonine kinase NEK3, which was reported to enhance bre
173 reen, we identified a mitotic-related serine/threonine kinase, NEK6, as a mediator of androgen-indepe
174 canonical NF-kappaB signaling via the serine/threonine kinase NIK (NF-kappaB-inducing kinase) remains
175 ated by the liver kinase B1 (LKB1), a serine-threonine kinase of the calcium calmodulin family.
176 ocated within STK32C, which encodes a serine/threonine kinase, of unknown function.
177 of these binding partners include the serine/threonine kinases, p21-activated kinase 1 (PAK1), apopto
178  determined that d-flow activated the serine/threonine kinase p90RSK, which subsequently phosphorylat
179       Ovaries in flies mutant for the serine/threonine kinase Pak exhibit a novel phenotype, in which
180                                       Serine/threonine kinase PAK1 is activated by estrogen and plays
181                     The p21-activated serine-threonine kinase (PAK1) regulates cell motility and adhe
182                 We determine that the serine/threonine kinase Par1b defines lumen position in concert
183        The protein kinase D family of serine/threonine kinases, particularly PKD1, has been implicate
184 The hypoxia-inducible, pro-oncogenic, serine-threonine kinase PIM1 (Proviral Integration site for Mol
185              PKD is a family of three serine/threonine kinases (PKD-1, -2, and -3) involved in the re
186      We found that RhoA activated the serine-threonine kinases PKN1 and PKN2 that bind and phosphoryl
187                        In eukaryotes, serine/threonine kinases play a central role in antiviral respo
188                Dysregulated oncogenic serine/threonine kinases play a pathological role in diverse fo
189                              IRAK4, a serine/threonine kinase, plays a key role in both inflammation
190                    The Akt protein, a serine/threonine kinase, plays important roles in cell survival
191                       The polo family serine threonine kinase Plk4 has been proposed as a therapeutic
192                 GSK3 is a pleiotropic serine-threonine kinase point of convergence of numerous cell-s
193                We have identified the serine/threonine kinase Polo-like kinase 1 (PLK1) as a host kin
194 role for the cell division regulating serine/threonine kinase polo-like kinase 2 (PLK2).
195 terphase of the cell cycle by NEK7, a serine-threonine kinase previously linked to mitosis.
196 coupled receptor kinase 5 (GRK5) is a serine/threonine kinase previously shown to mediate polymicrobi
197 RIPK1 and RIPK3, a pair of homologous serine/threonine kinases previously implicated in the regulatio
198 horylated by the MST1 (Hippo homolog) serine-threonine kinase, previously shown to be an AR repressor
199 echanistic target of rapamycin (mTOR) serine/threonine kinase promotes myelination, but factors that
200 A bioinformatic screen identified the serine-threonine kinase protein kinase D2 (PRKD2) as a potentia
201 the expression of the Golgi-localized serine-threonine kinase protein kinase D3 (PKD3) is elevated in
202 dually suppressed RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK signaling through the intera
203 ike kinase 1 (ALK1) is an endothelial serine-threonine kinase receptor for bone morphogenetic protein
204  and both protein-tyrosine kinase and serine/threonine kinase receptor transactivation concomitantly
205                          In contrast, serine/threonine kinase receptor transactivation is mediated by
206                    Here, we show that serine-threonine kinase receptor-associated protein (STRAP) is
207                                Type 1 Serine/Threonine Kinase Receptors (STKR1) transduce a wide spec
208 ediate signals via transactivation of serine/threonine kinase receptors, most notably the transformin
209                               The RAF serine/threonine kinases regulate cell growth through the MAPK
210 n synthase kinase-3 (GSK-3) family of serine/threonine kinases regulates several of these pathways, b
211 ng protein kinase (Hipk), a conserved serine-threonine kinase, regulates numerous factors during tiss
212 cell polarity protein Par-1 (MARK), a serine-threonine kinase, regulates the localization and activat
213 a B (AURKB) and Aurora C (AURKC), are serine/threonine kinases required for the control of mitosis (A
214 c approach identified PKCtheta as the serine/threonine kinase responsible for alphaPIX serine phospho
215 P-dependent protein kinase (PKA) is a serine/threonine kinase responsible for most of the effects of
216  siRNA-mediated inhibition of various serine/threonine kinases revealed ERK1/2 as a positive regulato
217 RNA virus, triggers activation of the serine-threonine kinases RIP1 and RIP3, which damages mitochond
218                                   The serine/threonine kinase RIPK1 is recruited to TNFR1 to mediate
219          Necroptosis is driven by two serine threonine kinases, RIPK1 (Receptor Interacting Protein K
220 e translocation and activation of the serine/threonine kinase ROCK1, a downstream target of the RhoA
221 ORC1 activation deploys the ribosomal serine/threonine kinase S6K1 and Polycomb proteins at genomic r
222 ess downregulates the activity of the serine/threonine kinase Shaggy (Sgg; also known as GSK-3).
223 fibrosis-relevant tyrosine kinase and serine/threonine kinase signaling pathways.
224 d by mass spectrometry identified the serine-threonine kinase SPEG as the only novel binding partner
225 d by mass spectrometry identified the serine-threonine kinase SPEG as the only novel binding partner
226                         Silencing the serine/threonine kinase STK11 (also known as LKB1) in HT-29 cel
227 kers, one (rs10937625) located in the serine/threonine kinase STK32B and one (rs17590046) in the tran
228        YAP1 is under the control of a serine-threonine kinase, STK4.
229 o interferes with the activity of the serine/threonine kinase StkP, the central regulator of pneumoco
230              In plants and algae, the serine/threonine kinase STN7/STT7, orthologous protein kinases
231  Trans-membrane signaling involving a serine/threonine kinase (Stt7 in Chlamydomonas reinhardtii) dir
232 ranscription factor NF-kappaB via the serine/threonine kinase TAK1.
233 dentifying degrader hits based on the serine/threonine kinase TANK-binding kinase 1 (TBK1) and have g
234 enerated Taok3(-/-) mice, lacking the serine/threonine kinase Taok3, and found cell-intrinsic defects
235  that shRNA-mediated knockdown of the serine/threonine kinases TESK1 or LIMK2 promoted mesenchymal-to
236                             mTOR is a serine/threonine kinase that acts as a central cellular censor
237            LKB1 is a multi-functional serine/threonine kinase that associates with actin at the cellu
238  MEKK2 (MAP/ERK kinase kinase-2) is a serine/threonine kinase that belongs to the MEKK/STE11 family o
239 istic target of rapamycin (mTOR) is a serine-threonine kinase that coordinates nutrient and growth fa
240 et of rapamycin (mTOR) is an atypical serine/threonine kinase that exerts its main cellular functions
241 et of rapamycin (mTOR) is a conserved serine/threonine kinase that forms two complexes, mTORC1 and mT
242 protein kinase 2 (HIPK2) is a nuclear serine/threonine kinase that functions in development and tumor
243     Integrin-linked kinase (ILK) is a serine/threonine kinase that has been linked to human and exper
244                        LKB1 encodes a serine/threonine kinase that has critical roles in cell growth,
245 eta1 (LKB1, also known as STK11) is a serine/threonine kinase that has multiple cellular functions in
246                            GSK-3 is a serine/threonine kinase that has numerous substrates.
247  Escherichia coli is a eukaryote-like serine-threonine kinase that inhibits cell growth and induces p
248 eptor-interacting protein (RIP1) is a serine/threonine kinase that integrates inflammatory and necrop
249     Specifically, we show that NLK, a serine/threonine kinase that interacts with ATXN1, modulates di
250                             AMPK is a serine/threonine kinase that is activated by upstream kinases L
251 t cyclin-dependent kinase 5 (Cdk5), a serine-threonine kinase that is highly active in postmitotic ne
252 osal and the activation of Akt/PKB, a serine/threonine kinase that is obligate for insulin-stimulated
253 osphatidylinositol 3-kinase-dependent serine/threonine kinase that is rapidly induced in response to
254                             Cdc7 is a serine-threonine kinase that phosphorylates components of the p
255 F2K), a Ca(2)(+)/calmodulin dependent serine/threonine kinase that phosphorylates eEF2 and regulates
256 1-like kinase 1 (ULK1) is a conserved serine-threonine kinase that plays a central role in the initia
257    p21-activated kinase-1 (Pak1) is a serine/threonine kinase that plays a key role in mediating anti
258 uiring enzyme 1alpha (IRE1alpha) is a serine-threonine kinase that plays crucial roles in activating
259 is a highly conserved and pleiotropic serine/threonine kinase that promotes many prosurvival and proi
260 re we identify Stk2, a staphylococcal serine/threonine kinase that provides efficient immunity agains
261 alian target of rapamycin (mTOR) is a serine/threonine kinase that regulates a diverse array of cellu
262 e A (PKA) is a ubiquitously expressed serine/threonine kinase that regulates a variety of cellular fu
263 alian target of rapamycin (mTOR) is a serine/threonine kinase that regulates processes including mRNA
264 Tumor progression locus 2 (Tpl2) is a serine-threonine kinase that regulates Th1 differentiation, sec
265     Integrin-linked kinase (ILK) is a serine-threonine kinase that transduces extracellular matrix-re
266 ed kinases (PAKs) are a family of six serine/threonine kinases that act as key effectors of RHO famil
267 OCK1 and ROCK2) are highly homologous serine/threonine kinases that act on substrates associated with
268                                       Serine-threonine kinases that activate NKCC2 have been identifi
269  The p21-activated kinases (Paks) are serine/threonine kinases that are major effectors of the Rho gu
270  LegK1-4 proteins are eukaryotic-like serine/threonine kinases that are translocated by the Dot/Icm t
271 CK) is a member of a diverse group of serine/threonine kinases that feature cytoskeletal association.
272                NEK family kinases are serine/threonine kinases that have been functionally implicated
273 nase catalytic subunit (DNA-PKcs) are serine-threonine kinases that orchestrate the cellular response
274 ceptor-associated kinases (IRAKs) are serine/threonine kinases that play critical roles in initiating
275 ho kinases, or ROCKs, are a family of serine-threonine kinases that serve as key downstream effectors
276 repeats, a transmembrane domain and a serine/threonine kinase, the rice (Oryza sativa) protein XA21 c
277 gnaling pathway consists of conserved serine/threonine kinases to maintain optimal organ sizes.
278           The translocation of Akt, a serine/threonine kinase, to the plasma membrane is a critical s
279                                   The serine-threonine kinase TOR, the Target of Rapamycin, is an imp
280                   The testis-specific serine/threonine kinases (TSSKs) comprise a family of post-meio
281                                   The serine/threonine kinase tumor progression locus 2 (Tpl2, also k
282 through binding and activation of the serine/threonine kinase type II TGF-beta receptor (TbetaRII), w
283 n of the MTOR complex 1 (RAPTOR), the serine/threonine kinase V-Akt murine thymoma viral oncogene hom
284          TSSK1, -2, -4, and -6 (small serine/threonine kinase) were all found to associate with HSP90
285 pe II (TbetaRII) and type I (TbetaRI) serine/threonine kinases, whereby Smad2 and Smad3 are phosphory
286 kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly active in the nervous s
287  CASK (a calcium/calmodulin-activated serine/threonine kinase), which binds to neurexins, and mutatio
288  interacts with calmodulin-associated serine/threonine kinase, which is implicated in X-linked mental
289 PAK4 is a member of the PAK family of serine/threonine kinases, which act as effectors for several sm
290                   AMPK is a conserved serine/threonine kinase whose activity maintains cellular energ
291 se II (CaMKII) is a calcium-regulated serine threonine kinase whose functions include regulation of s
292  protein kinase (AMPK) is a conserved serine/threonine kinase with a critical function in the regulat
293 ied MAST205 (a microtubule-associated serine/threonine kinase with a molecular mass of 205 kDa) as a
294 coupled receptor kinase 2 (GRK2) is a serine/threonine kinase with an important function in the desen
295 racting protein kinase 3 (RIPK3) is a serine/threonine kinase with essential function in necroptosis.
296 eting oncogenic mutations in the BRAF serine/threonine kinase with small molecule inhibitors can lead
297  polo-like kinases (PLK), a family of serine/threonine kinases with well-known roles in cell cycle re
298         Two of these genes encode the serine-threonine kinases WNK1 and WNK4.
299                                       Serine threonine kinase WNK4 (With No K = lysine member 4) and
300                 One such protein, the serine/threonine kinase YopO (YpkA in Yersinia pestis), uses mo

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