ライフサイエンスコーパス: threonine phosphatase

1 4 (PP4; also called PPX and PPP4), a serine/threonine phosphatase.

2 with protein phosphatase 2A (PP2A), a serine/threonine phosphatase.

3 catalytic subunit of a type 1 protein serine/threonine phosphatase.

4 t the activity of PP2A, another major serine/threonine phosphatase.

5 hosphatase and a protein phosphatase 2A-like threonine phosphatase.

6 trols a serine/threonine kinase and a serine/threonine phosphatase.

7 ovel PKC isozyme and a bFGF-dependent serine/threonine phosphatase.

8 losporin-sensitive, calcium-regulated serine/threonine phosphatase.

9 is a highly conserved and ubiquitous serine/threonine phosphatase.

10 ture-function studies of this protein serine/threonine phosphatase.

11 during platelet aggregation activates serine/threonine phosphatases.

12 members of the PP2C class of protein serine/threonine phosphatases.

13 ut the expression and function of the serine-threonine phosphatases.

14 te with members of the PP2A family of serine/threonine phosphatases.

15 th calyculin A, a potent inhibitor of serine/threonine phosphatases.

16 P2A) is a member of the intracellular serine/threonine phosphatases.

17 A), an abundantly expressed family of serine-threonine phosphatases.

18 D was rapidly dephosphorylated by the serine-threonine phosphatase 1 alpha, and localized in the mito

19 on of mitotic FAK in vitro by protein serine/threonine phosphatase 1 restores the ability of FAK to a

20 In the cortex, mRNAs for neuronal tyrosine/threonine phosphatase 1, and microtubule-associated tau

21 of heat shock protein 90 and protein serine/threonine phosphatase 1-alpha.

22 otably, genetic disruption of protein serine/threonine phosphatase-1 (PP1) and its regulator NIPP1 de

23 in vivo evidence to show that protein serine/threonine phosphatase-1 is a major phosphatase that dire

24 ctive site is highly conserved in the serine/threonine phosphatase-1 subfamily, but not in the serine

25 P2R1A encodes a regulatory subunit of serine/threonine phosphatase 2, and ARID1A encodes adenine-thym

26 and is abolished by inhibition of serine and threonine phosphatase 2A (PP-2A).

27 Protein serine/threonine phosphatase 2A (PP2A) activity must be tightly

28 ing experiments indicate that protein serine/threonine phosphatase 2A (PP2A) can dephosphorylate thes

29 indicates that regulation of protein-serine/threonine phosphatase 2A (PP2A) involves its association

30 Protein serine/threonine phosphatase 2A (PP2A) is a critical regulator

31 Protein serine/threonine phosphatase 2A (PP2A) is a multifunctional reg

32 Protein serine/threonine phosphatase 2A (PP2A) regulates a wide variety

33 metric complex of CaMKIV with protein serine-threonine phosphatase 2A (PP2A) was identified in which

34 nase cascades, heterotrimeric protein serine/threonine phosphatase 2A (PP2A), is composed of catalyti

35 hown to stably associate with protein serine/threonine phosphatase 2A (PP2A), which was proposed to p

36 eral kinases and inhibited by protein serine/threonine phosphatase 2A (PP2A).

37 how that polyamine depletion inhibits serine/threonine phosphatase 2A (PP2A).

38 eam repressor COUP-TFII by inhibiting serine/threonine phosphatase 2A activity, and that decreased CO

39 nase 2 activity and increased protein serine/threonine phosphatase 2A activity, resulting in an incre

40 protein HOX11 interacted with protein serine-threonine phosphatase 2A catalytic subunit (PP2AC), as w

41 s control the activity of the protein serine/threonine phosphatase 2A catalytic subunit (PP2Ac), incl

42 Casein kinase 2 catalyzed protein serine/threonine phosphatase 2A phosphorylation thereby inhibit

43 asein kinase 2 complexed with protein serine/threonine phosphatase 2A.

44 n between casein kinase 2 and protein serine/threonine phosphatase 2A.

45 Sp1 binding via the action of protein serine/threonine phosphatase 2A.

46 EGCG can negatively regulate protein serine/threonine phosphatase-2A (PP-2A) to positively regulate

47 osphatase-1 subfamily, but not in the serine/threonine phosphatase-2A or -2B subfamilies.

48 The catalytic subunit of protein serine/threonine phosphatase 4 (PP4C) has greater than 65% amin

49 nd regulatory subunits of the protein serine/threonine phosphatase 4 complex (PP4c/PP4R1).

50 egulatory linkage between the protein serine-threonine phosphatase 5 (PP5) and ATM.

51 Serine/threonine phosphatase 5 (PP5) can act as a suppresser of

52 ding purple acid phosphatase, protein serine/threonine phosphatases, 5'-nucleotidase, and DNA repair

53 pitated c-Fos protein with the type 2 serine/threonine phosphatase A (PP2A) and immunoblotting of c-F

54 tment with either protein tyrosine or serine/threonine phosphatases abolished its activity.

55 dephosphorylation through endogenous serine/threonine phosphatase action.

56 e transactivation, tyrosine phosphatase, and threonine phosphatase activities in their function as pa

57 Moreover, the PST/TPM and the threonine phosphatase activity are not required for in v

58 -free cell lysates, we find increased serine/threonine phosphatase activity associated with Golgi-enr

59 HOX11 also inhibited PP2A serine/threonine phosphatase activity concomitant with stimulat

60 Serine-threonine phosphatase activity dephosphorylated BAD in i

61 tination of proteins, we examined the serine/threonine phosphatase activity in our CAOV3 cells follow

62 We also find that the threonine phosphatase activity plays only a minor role d

63 of Eya1 to the nucleus, where Eya1 uses its threonine phosphatase activity to control Myc phosphoryl

64 by KCC2 is completely independent of serine-threonine phosphatase activity, suggesting that these tw

65 een shown to have modest tyrosine and serine/threonine phosphatase activity, we find that it is much

66 expressed in mammalian cells exhibit serine-threonine phosphatase activity, which requires Mn2+ and

67 lated c-Jun, and by the inhibition of serine/threonine phosphatase activity.

68 al kinase activity but to a decreased serine/threonine phosphatase activity.

69 mechanism whereby Ca(2+) can activate serine/threonine phosphatase activity.

70 ing PP1cgamma, a catalytic subunit of serine/threonine phosphatase, alpha(IIb)beta3 failed to dephosp

71 Inhibition of serine/threonine phosphatases also enhanced sickle erythrocyte

72 tingly, okadaic acid, an inhibitor of serine/threonine phosphatase, also strongly activated transcrip

73 t protein phosphatase 1) is a protein-serine/threonine phosphatase and a negative regulator of the PI

74 Loss of the PrpC serine-threonine phosphatase and the associated PrkC kinase of

75 ase C (PKC) activation, inhibition of serine/threonine phosphatase, and an active protein tyrosine ph

76 phatase-2A (PP2A), a widely expressed serine/threonine phosphatase, and the heterotrimeric G protein

77 ing several tyrosine phosphatases and serine/threonine phosphatases, and it suppresses the cell growt

78 applicable to other DUSPs and protein-serine/threonine phosphatases, and the substrate specificity da

79 otein phosphatase 2A (PP2A) family of serine-threonine phosphatases, and this interaction is required

80 Protein serine-threonine phosphatases are assembled from catalytic subu

81 All of the known protein serine/threonine phosphatases are expressed in the brain.

82 The activity and specificity of serine/threonine phosphatases are governed largely by their ass

83 phosphoprotein phosphatase family of serine/threonine phosphatases are thought to exist in different

84 osphatase-1 (PP1), a major eukaryotic serine/threonine phosphatase, are defined by the association of

85 ), potent and selective inhibitors of serine threonine phosphatases, are of interest for their antitu

86 In this review, we present protein serine/threonine phosphatases as viable therapeutic targets, di

87 cells, we identify PP2A as the first serine/threonine phosphatase associated with the multiprotein T

88 phatase 4 (PP4), a novel PP2A-related serine/threonine phosphatase, at a 50% inhibitory concentration

89 ined the regulatory interactions of a serine/threonine phosphatase (BA-Stp1), serine/threonine kinase

90 s the sequence hallmarks of a phospho-serine/threonine phosphatase belonging to the PPP family.

91 cells, it was determined that PP2A, a serine/threonine phosphatase, binds and dephosphorylates Rb2/p1

92 ase kinase-3-like kinase (BIN2) and a serine/threonine phosphatase (BSU1).

93 The serine-threonine phosphatase calcineurin (Cn)A plays a critical

94 1) cell cycle arrest, implicating the serine/threonine phosphatase calcineurin as one Ca(2+)/CaM-depe

95 ) and the Ca(2+)/calmodulin-activated serine/threonine phosphatase calcineurin exist and play a role

96 The serine/threonine phosphatase calcineurin is an important regula

97 e revealed that the calcium-dependent serine/threonine phosphatase calcineurin mediates the effects o

98 tion is modulated by Ca(2+)-dependent serine/threonine phosphatase calcineurin, an important target o

99 o explore the redox regulation of the serine/threonine phosphatase calcineurin, we have investigated

100 y of the calcium/calmodulin-dependent serine/threonine phosphatase calcineurin.

101 nals regulate MEF2 activity through a serine/threonine phosphatase calcineurin.

102 , an immunosuppressant inhibiting the serine/threonine phosphatase calcineurin.

103 sphorylation are all modulated by the serine/threonine phosphatase calcineurin.

104 sphorylation by the calcium-dependent serine/threonine phosphatase calcineurin.

105 ecificity phosphatase (cdc25b), and a serine/threonine phosphatase (calcineurin).

106 discovered to be an inhibitor of the serine/threonine phosphatase, calcineurin, and its signaling pa

107 the calcium and calmodulin activated serine/threonine phosphatase, calcineurin.

108 and treatment of cRaf-1 with protein (serine/threonine) phosphatases can deactivate it, at least part

109 ent of CKIepsilon with any of several serine/threonine phosphatases causes a marked increase in kinas

110 The mRNA encoding a tyrosine/threonine phosphatase (CL100/MKP-1) was also NO inducibl

111 (PP2A) is a family of multifunctional serine/threonine phosphatases consisting of a catalytic C, a st

112 hatase-1, revealed that this class of serine/threonine phosphatases contain in their putative active

113 (PP2A) is an abundant heterotrimeric serine/threonine phosphatase containing highly conserved struct

114 ation and PDZ-mediated formation of a serine/threonine phosphatase-containing complex by syndecan-4 a

115 in view of literature suggesting that serine/threonine phosphatases could be subject to redox control

116 The protein serine/threonine phosphatase designated PP5 has little basal ac

117 Inhibition of serine/threonine phosphatases did not affect the activity of th

118 the dephosphorylation events via the serine/threonine phosphatases during the integrin outside-in si

119 nlike kinases, it remains unclear how serine/threonine phosphatases engage the signaling networks tha

120 gh homology to the dual-specificity tyrosine/threonine phosphatase family of proteins.

121 ubiquitously expressed member of the serine-threonine phosphatase family that is involved in regulat

122 inases Cdk7 and Cdk9, whereas protein serine/threonine phosphatase FCP1 dephosphorylates CTD.

123 We have identified a novel type 2C serine-threonine phosphatase, FIN13, whose expression is induce

124 rprisingly, this structure revealed a serine/threonine phosphatase fold that unexpectedly targets tyr

125 omologue of the PPM family of protein-serine/threonine phosphatases found in all eukaryotes as well a

126 phatase 2A (PP2A) is one of the major serine/threonine phosphatases found in eukaryotic cells.

127 ene for a putative PPP family protein-serine/threonine phosphatase from the microcystin-producing cya

128 (ORFs) encoding two potential protein-serine/threonine phosphatases from the cyanobacterium Synechocy

129 A putative protein serine/threonine phosphatase gene has been isolated from the hu

130 inant for the targeting of the type 1 serine/threonine phosphatase (Glc7) to the bud neck.

131 phosphatase X (PPX)), a PP2A-related serine/threonine phosphatase, has been shown to be involved in

132 Ptc1p, a serine/threonine phosphatase, has previously been shown to regu

133 Okadaic acid-sensitive serine/threonine phosphatases have been shown to regulate inter

134 ere we provide evidence that ppm-1, a serine/threonine phosphatase homologous to human PP2Calpha(PPM1

135 The inhibition of serine/threonine phosphatases, however, has no effect on AChR r

136 haromyces cerevisiae, is an essential serine/threonine phosphatase implicated in the regulation of a

137 tein phosphatase 2A (PP2A), the major serine/threonine phosphatase in eukaryotic cells, is a heterotr

138 rdgC) gene encodes an unusual protein serine/threonine phosphatase in that it contains at least two E

139 PTC1 encodes a serine/threonine phosphatase in the high-osmolarity glycerol re

140 r the involvement of a type 1 protein serine/threonine phosphatase in the ultraviolet radiation-induc

141 In this review, we concentrate on serine/threonine phosphatases in apicomplexan parasites, with t

142 nterference (RNAi)-based screening of serine/threonine phosphatases in Drosophila S2 cells, we identi

143 hosphatase 2A (PP2A), one of the main serine-threonine phosphatases in mammalian cells, maintains cel

144 vity of calcineurin, a Ca2+-dependent serine/threonine phosphatase, increases synaptic expression of

145 w that LTD expression is increased by serine/threonine phosphatase inhibition, and negatively regulat

146 The serine-threonine phosphatase inhibitor (OA) decreased NO releas

147 red for iNOS transcription, while the serine-threonine phosphatase inhibitor (OA) had no effect on iN

148 [PV], phenylarsine oxide [PAO]) and a serine-threonine phosphatase inhibitor (okadaic acid [OA]).

149 staglandin E(2), cAMP-raising agents, serine/threonine phosphatase inhibitor and activation of protei

150 The serine/threonine phosphatase inhibitor calyculin A (5 nM) sensi

151 e Ca(2+) ionophore ionomycin, and the serine/threonine phosphatase inhibitor calyculin A increased Se

152 We show that the serine/threonine phosphatase inhibitor calyculin A induces the

153 s citrate and tartrate or the protein serine/threonine phosphatase inhibitor okadaic acid.

154 ated by treatment with calyculin A, a serine/threonine phosphatase inhibitor that elevates MLC phosph

155 kinases A and C, and okadaic acid (a serine/threonine phosphatase inhibitor) decreased the current c

156 -fibrinogen blocker) or okadaic acid (serine/threonine phosphatase inhibitor) dramatically enhanced E

157 t of eosinophils with okadaic acid, a serine/threonine phosphatase inhibitor, at the concentrations t

158 s, the tumor promoter okadaic acid, a serine-threonine phosphatase inhibitor, increased binding of ac

159 n by nickel; however, okadaic acid, a serine/threonine phosphatase inhibitor, induced Cap43 to a grea

160 n cells were lysed in the presence of serine/threonine phosphatase inhibitor, NaF, the PKA-enhancing

161 ere treated with okadaic acid (OA), a serine/threonine phosphatase inhibitor, to induce tau phosphory

162 ansport stimulated by okadaic acid, a serine/threonine phosphatase inhibitor, was also 45% lower with

163 KCC2 is completely resistant to this serine-threonine phosphatase inhibitor.

164 The addition of the serine/threonine phosphatase inhibitors calyculin A and microcy

165 ivo skin and esophagus cultures, with serine/threonine phosphatase inhibitors causes a dramatic incre

166 Treatment of cells with serine and threonine phosphatase inhibitors had no effect on ankyri

167 cytosol, is resistant to the classic serine/threonine phosphatase inhibitors okadaic acid and microc

168 ment of cells with the cell-permeable serine/threonine phosphatase inhibitors okadaic acid or calycul

169 Treatment of erythroid cells with serine and threonine phosphatase inhibitors stimulated the hyperpho

170 el activation are inhibited by type 1 serine/threonine phosphatase inhibitors.

171 hibitor of type 1 and type 2A protein serine/threonine phosphatase, inhibits both receptor-induced ac

172 phatases modulate GPCR signaling, how serine/threonine phosphatases integrate with G protein signalin

173 oskeletal associated protein, proline serine threonine phosphatase interacting protein (PST PIP), via

174 ed in the identification of proline, serine, threonine phosphatase interacting protein (PSTPIP), a no

175 2BP1 and its murine ortholog, proline-serine-threonine phosphatase interacting protein (PSTPIP1), are

176 ology family protein PSTPIP2 (proline-serine-threonine phosphatase interacting protein 2), spontaneou

177 imilarity with the PST PIP (proline, serine, threonine phosphatase interacting protein)/CDC15 family

178 oskeletal-associated protein, proline-serine-threonine phosphatase-interacting protein (PSTPIP), whos

179 interaction between pyrin and proline serine threonine phosphatase-interacting protein 1 (PSTPIP1), t

180 ant missense mutations in the proline-serine-threonine phosphatase-interacting protein 1 gene (PSTPIP

181 Missense mutation in the proline-serine-threonine phosphatase-interacting protein 2 (Pstpip2) ge

182 Missense mutation (L98P) of proline-serine-threonine phosphatase-interacting protein 2 (Pstpip2) in

183 ouse Lupo (I282N) mutation in proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2) le

184 ns of anti-inflammatory IL37, proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), a

185 of the F-BAR domain protein, proline serine threonine phosphatase-interacting protein 2 (PSTPIP2), l

186 We now show that proline serine threonine phosphatase-interacting protein [PSTPIP1, or C

187 utations in the gene encoding proline serine threonine phosphatase-interacting protein-1 (PSTPIP1) ha

188 phatase 2A (PP2A) is a heterotrimeric serine/threonine phosphatase involved in essential cellular fun

189 osphatase-2A (PP2A) is a multisubunit serine/threonine phosphatase involved in intracellular signalin

190 ein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cell proli

191 The multifunctional activity of many serine/threonine phosphatases is achieved through their associa

192 ein phosphatase 1 (PP1), a ubiquitous serine/threonine phosphatase, is a novel potent positive physio

193 Calcineurin, a serine-threonine phosphatase, is activated by calcium and calmo

194 2A (PP2A) is an essential eukaryotic serine/threonine phosphatase known to play important roles in c

195 receptors such as CTLA-4 and CD28 and serine/threonine phosphatases may represent a novel mechanism f

196 ne-Threonine)-rich transactivation domain, a threonine phosphatase motif (TPM), and a tyrosine protei

197 ae, we isolated PTC2, which encodes a serine/threonine phosphatase of type 2C.

198 Addition of the inhibitor-of-protein serine/threonine phosphatases, okadaic acid, blocks the ATRA-me

199 Affinity isolation of protein serine/threonine phosphatases on the immobilized phosphatase in

200 alcineurin because inhibitors of this serine/threonine phosphatase partially rescue the block to adip

201 IRS1 and increased expression of the serine/threonine phosphatase Phlpp1.

202 by inducing the expression of the serine and threonine phosphatase Phlpp1.

203 PPM1A, a metal ion-dependent protein serine/threonine phosphatase, physically interacts with and dep

204 ggest that the PPEF family of protein serine/threonine phosphatases plays a specific and conserved ro

205 nduced activation of NF-kappaB, while serine-threonine phosphatases posttranscriptionally regulate iN

206 Protein serine/threonine phosphatase (PP) 2A is a ubiquitous enzyme wit

207 lated with inhibition of the major Rb serine/threonine phosphatase PP1.

208 Serine/threonine phosphatases PP1 and PP2A, which are closely r

209 not significantly inhibit the protein serine/threonine phosphatases PP1 and PP2A.

210 activated inhibitor of type 1 protein serine/threonine phosphatase (PP1), in a yeast two-hybrid scree

211 tor that activates the type 1 protein serine/threonine phosphatase (PP1), which dephosphorylates eIF-

212 Type-1 protein serine/threonine phosphatases (PP1) are uniquely inhibited by t

213 2) selectively inhibit type 1 protein serine/threonine phosphatases (PP1).

214 s of highly expressed skeletal muscle serine/threonine phosphatases (PP1, PP2A, PP2B, and PP2C) on AS

215 cal regulation of two major mammalian serine/threonine phosphatases, PP1 and PP2A.

216 stable and active complexes with the serine/threonine phosphatases PP1beta and PP1gamma, enzymes tha

217 Inhibition of the serine/threonine phosphatase, PP2-A, with okadaic acid resulted

218 a was due, in part, to an increase in serine/threonine phosphatase PP2A activity.

219 Furthermore, we found that the serine/threonine phosphatase PP2A also regulates FoxO3a.

220 due to the combined activities of the serine/threonine phosphatase PP2A and the tyrosine phosphatase

221 We find that the serine/threonine phosphatase PP2A can physically associate with

222 usly unrecognized requirement for the serine-threonine phosphatase PP2A in the function of T(reg) cel

223 family of tyrosine phosphatases, the serine/threonine phosphatase PP2A, and cholesterol.

224 hosphatase activity that contains the serine/threonine phosphatase PP2A, the tyrosine phosphatase HeP

225 is mediated by the activation of the serine/threonine phosphatase PP2A.

226 ssion of the catalytic subunit of the serine-threonine phosphatase PP2A.

227 is dependent upon the activity of the serine/threonine phosphatase PP2A.

228 an inhibitor of the major PPP family serine/threonine phosphatases PP2A and protein phosphatase 1 (P

229 sed by SCF through phosphorylation of serine/threonine phosphatase (PP2A) and correlated well with fe

230 lated by a tightly associated protein serine-threonine phosphatase (PP2A).

231 mediated, in part, by type 2A protein serine/threonine phosphatases (PP2A).

232 ied with the main two subunits of the serine/threonine phosphatase, PP2A.

233 n a strain lacking functional type 2C serine/threonine phosphatases (PP2C), Ptc1 and Ptc3.

234 Two serine/threonine phosphatases, PP2Calpha and PP2A, were not sig

235 hysiological evidence for the protein serine/threonine phosphatase, PP5, as an effector of Rac GTPase

236 The serine/threonine phosphatase PPM1D/Wip1 inactivates p53 and pro

237 e show that the oncogenic p53-induced serine/threonine phosphatase, PPM1D (or Wip1), dephosphorylates

238 now identify a potential role for the serine-threonine phosphatase PPM1G in translational regulation

239 Selective inhibitors for each serine/threonine phosphatase (PPP) are essential to investigate

240 at identifies the PP2A heterotrimeric serine/threonine phosphatases PPP2R2A, PPP2R2D, PPP2R5A, and PP

241 conserved regions within the protein-serine/threonine phosphatases (PPs) of the PP1/2A/2B superfamil

242 regulation of okadaic acid-sensitive serine/threonine phosphatases; presumably, these phosphatases a

243 enes or the disruption of the general serine-threonine phosphatase protein phosphatase 2A (PP2A) can

244 The serine/threonine phosphatase protein phosphatase 2A (PP2A) play

245 the post-translational level, by the serine-threonine phosphatase protein phosphatase 2A (PP2A).

246 The serine/threonine phosphatase protein phosphatase 5 (PP5) regula

247 ) and gamma chain and also endogenous serine/threonine phosphatase protein phosphates 1 and/or 2A act

248 hibition of tyrosine phosphatases and serine/threonine phosphatases protein phosphatase 1 (PP1), PP2A

249 pproach, we have identified a protein serine/threonine phosphatase, protein phosphatase 2A (PP2A), as

250 lso inactivated by treatment with the serine/threonine phosphatase, protein phosphatase 2A; okadaic a

251 Mycobacterium tuberculosis, only one serine/threonine phosphatase, PstP, has been identified.

252 SH2-B with protein phosphatase 2A, a serine/threonine phosphatase, reduces the many forms to two.

253 Elucidating how serine/threonine phosphatases regulate kinase function and bact

254 rotein phosphatase 2A (PP2A), a major serine-threonine phosphatase, regulates similar biologic proces

255 n phosphatase 1 (PP1) is a ubiquitous serine/threonine phosphatase regulating many cellular processes

256 se I (PP1) is an essential eukaryotic serine/threonine phosphatase required for many cellular process

257 orylation pathway mediated by PKC and serine/threonine phosphatase(s).

258 r to be mediated by the activation of serine-threonine phosphatase, since they are blocked by low dos

259 m molybdate) but not by inhibitors of serine/threonine phosphatases (sodium fluoride, okadaic acid, a

260 e precise role of the co-transcribing serine/threonine phosphatase (SP-STP) has remained enigmatic.

261 important property of eukaryote-type serine/threonine phosphatase (SP-STP) of group A Streptococcus

262 he presence or absence of the cognate serine/threonine phosphatase Stp1 affects Stk1 function and GBS

263 mechanism was identified involving a serine/threonine phosphatase, Stp1.

264 id the taste, is dependent on several serine/threonine phosphatase substrates and the PP1-binding pro

265 nhibition of all known subfamilies of serine/threonine phosphatases, suggesting that multiple phospha

266 PP5 is a serine/threonine phosphatase that also contains four copies of

267 Here, we identify PP1 as a serine/threonine phosphatase that associates with and dephospho

268 phosphatase 2A (PP2A) is a multimeric serine/threonine phosphatase that carries out multiple function

269 Calcineurin is a serine/threonine phosphatase that contributes to the effects of

270 iments were performed to identify the serine/threonine phosphatase that dephosphorylates FOXO1.

271 p53-induced phosphatase 1 (WIP1) is a serine/threonine phosphatase that dephosphorylates proteins in

272 in is a calcium-calmodulin-regulated, serine-threonine phosphatase that functions as a key inducer of

273 Calcineurin is a calcium-dependent, serine/threonine phosphatase that functions as a signaling inte

274 Calcineurin is a serine/threonine phosphatase that is activated by calcium and c

275 binds to and inhibits calcineurin, a serine/threonine phosphatase that is activated by TCR engagemen

276 hatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many cellular

277 have recently reported that a protein serine/threonine phosphatase that is designated PP5 and contain

278 The Wip1 gene is a serine/threonine phosphatase that is induced in a p53-dependent

279 ylation of this site is mediated by a serine/threonine phosphatase that is inhibited by okadaic acid

280 Calcineurin is a serine/threonine phosphatase that is inhibited by the immunosup

281 uced phosphatase PPM1D (or Wip1) is a serine/threonine phosphatase that is transcriptionally upregula

282 ates protein phosphatase 2A (PP2A), a serine/threonine phosphatase that modulates essential signaling

283 phosphatase 2A (PP2A) is an important serine/threonine phosphatase that plays a role in many biologic

284 tein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that regulates a wide variety of c

285 (Cn) is a Ca(2+)/calmodulin-dependent serine/threonine phosphatase that regulates differentiation-spe

286 n phosphatase 1 (PP1) is a ubiquitous serine/threonine phosphatase that regulates many cellular proce

287 inhibited activity of calcineurin, a serine/threonine phosphatase that regulates NFAT activation.

288 B) is a calcium/calmodulin-activated, serine-threonine phosphatase that transmits signals to the nucl

289 se 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the control o

290 onserved between different eukaryotic serine/threonine phosphatases, these results should apply to al

291 ion of protein phosphatase 1 gamma, a serine/threonine phosphatase, to rat liver cytosol reduced acti

292 F appears to be mediated by a protein serine/threonine phosphatase type 1 or 2A.

293 A complete cDNA of a unique serine/threonine phosphatase type five (TbPP5) was cloned and c

294 se active site has been identified in serine-threonine phosphatases using a descriptor built from the

295 early events, the activity of protein serine/threonine phosphatases was markedly increased in the cel

296 ed cancer genes was PPP6C, encoding a serine/threonine phosphatase, which harbored mutations that clu

297 belongs to the PPM family of protein serine/threonine phosphatases, which, in spite of a low level o

298 phosphatase-2A (PP2A) is an abundant serine/threonine phosphatase with anti-inflammatory activity.

299 PX or PPP4) is a PP2A-related protein serine/threonine phosphatase with important roles in a variety

300 ontains a mutation in PTC1, a type 2c serine/threonine phosphatase with widespread influences.